Missouri Adults Only Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to CA $1,096 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Flight and Adults Only hotel deals in Missouri
Price found within the past 48 hours. Click for updated prices.
Moonrise Hotel
Delmar Loop
Price was CA $1,359, price is now CA $1,176 per person
CA $1,176
per person
Nov 26 - Dec 1
found 1 day ago
Roundtrip flight included
Vancouver (YVR) to St. Louis (STL)
9/10 Wonderful! (1,865 reviews)
The staff was great-so welcoming and engaged. Loved our stay here, and the rooftop is beautiful.
Reviewed on Sep. 3, 2025
3 Night Adults Only holidays in Missouri
Price found within the past 48 hours. Click for updated prices.
Moonrise Hotel
Delmar Loop
Price was CA $1,167, price is now CA $1,037 per person
CA $1,037
per person
Oct 21 - Oct 24
found 6 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
9/10 Wonderful! (1,865 reviews)
The staff was great-so welcoming and engaged. Loved our stay here, and the rooftop is beautiful.
Reviewed on Sep. 3, 2025
4 Night Adults Only holidays in Missouri
Price found within the past 48 hours. Click for updated prices.
Moonrise Hotel
Delmar Loop
Price was CA $1,390, price is now CA $1,246 per person
CA $1,246
per person
Oct 13 - Oct 17
found 1 day ago
Roundtrip non-stop flight included
Hamilton (YHM) to St. Louis (STL)
9/10 Wonderful! (1,865 reviews)
The staff was great-so welcoming and engaged. Loved our stay here, and the rooftop is beautiful.
Reviewed on Sep. 3, 2025
Adults Only Hotels in Missouri
Luxury Log Cabin - Fireplace - Bath - WIFI - Cable - Porch - Pool - Resort
Branson
Stay at this cabin in Branson. Enjoy free WiFi, a water park, and a fitness center. Popular attractions Branson Landing and Silver Dollar City are located ...
Westport Inn
3817 N Main St., Joplin, MO
The price is CA $95 per night from Sep 6 to Sep 7
CA $95
CA $101 total
Sep 6 - Sep 7
includes taxes & fees
Stay at this motel in Joplin. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions George A. Spiva Center for the Arts and Webb City ...
Historic Iron Horse Inn
207 E. 4th Street, Hermann, MO
Stay at this 3.5-star B&B in Hermann. Enjoy free breakfast, free parking, and a garden. Popular attractions Deutschheim State Historic Site and Hermannhof Vineyards ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More vacations you might like
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
