Title: Book The Best Hotels in Whetsell, SC for 2026 from CA $86 - Fully Refundable Options - Expedia.ca [Whetsell Travel Guide](https://expedia.ca/Whetsell.dx553248635974902828)[Vacation Rentals in Whetsell](https://expedia.ca/Whetsell-Vacation-Rentals.d553248635974902828.Travel-Guide-VacationRentals)[Whetsell Car Rentals](https://expedia.ca/Car-Rentals-In-Whetsell.d553248635974902828.Car-Rental-Guide)[Whetsell Vacation Packages](https://expedia.ca/Whetsell.d553248635974902828.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Whetsell Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-21&d1=2026-03-21&endDate=2026-03-23&d2=2026-03-23&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-21&d1=2026-03-21&endDate=2026-03-23&d2=2026-03-23&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Whetsell%2C+South+Carolina%2C+United+States+of+America®ionId=553248635974902828&latLong=33.333771%2C-80.590096&adults=2&startDate=2026-03-21&d1=2026-03-21&endDate=2026-03-23&d2=2026-03-23&amenities=PETS) ## Check prices for these dates Tonight [Mar 7 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=553248635974902828&startDate=2026-03-07&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 8 - Mar 9](https://www.expedia.ca/Hotel-Search?regionId=553248635974902828&startDate=2026-03-08&endDate=2026-03-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=553248635974902828&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=553248635974902828&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Whetsell hotels ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/6c8567ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/1f93ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/51caeaed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/0af71c77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Santee [](https://www.expedia.ca/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) Santee 6.4/10 (311 reviews) "Last minute arrangements stay was quiet and peaceful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iasia CA $93 CA $103 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/6fa02d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5f0b6fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very good (1,002 reviews) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $172 CA $191 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/0b55a618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very good (1,007 reviews) "Clean rooms, nice staff, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale CA $141 CA $156 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/4686cd8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/070e1043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/9e846421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee [](https://www.expedia.ca/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) Santee 6.6/10 (646 reviews) "A good option if traveling with pets. The hotel is clean and well maintained but dated. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $79 CA $88 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/e77a8624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/4c792a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee I-95 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) Santee 6.0/10 (478 reviews) "Clean room but needs an exhaust fan in the bathroom " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leesa CA $74 CA $89 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1,442 reviews) "Room were very clean and staff was very helpful. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charolette CA $109 CA $120 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/5b7ee831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/ebe97e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Santee 7.0/10 Good (703 reviews) "Nice quiet room and a delicious breakfast at a reasonable rate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph B CA $85 CA $95 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/67da47be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ec6d0d77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/044c704d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1,008 reviews) "Courteous reception,clean rooms and great breakfast! Have been there many times in the last 15 years and I will return.!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Roger CA $152 CA $169 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/1ffbf2b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) Santee 9.6/10 Exceptional (1,004 reviews) "Liked the size of the room, the staff and the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virginia CA $172 CA $191 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/40f69ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) Santee 9.2/10 Wonderful (750 reviews) "Large, clean room, friendly staff, nice breakfast. Would stay again. Also a nice Mexican restaurant nearby for dinner. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $155 CA $172 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/77599f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/dc3438b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) Santee 6.8/10 (444 reviews) "The staff was very friendly and helpful. Room was clean and beds were so comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy CA $102 CA $113 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/d654e116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1,012 reviews) "Room had everything we wanted... very clean & fresh, microwave, fridge, comfy beds. Hotel was very nice and close to everything needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia CA $170 CA $188 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/d34bd120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/13247169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/daa776a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/2def81ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Santee I-95 [](https://www.expedia.ca/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) Santee 6.4/10 (552 reviews) "Room was clean. Staff was friendly. Bartender was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dean CA $108 CA $119 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/b0419165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Tent | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/9123f55d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bells Marina & Resort [](https://www.expedia.ca/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) Eutawville 8.6/10 Excellent (90 reviews) "Super quaint, quiet, nice little get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen [](https://www.expedia.ca/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/e17744ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/515ae417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/38babe0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/a22ac41a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Budget Inn By Belvilla St George I-95 [](https://www.expedia.ca/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) St. George 7.6/10 Good (185 reviews) "This is a great value for a budget hotel. It's an older complex but clean and well maintained. It's close to decent food options for tired travelers and the front desk staff was pleasant and helpful. If you are looking for a convient, well priced stopover, I recommend this location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim [](https://www.expedia.ca/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e088653f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e85d0e8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/59cd1b4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham St George [](https://www.expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) St. George 7.6/10 Good (1,003 reviews) "Clean, relaxing, friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Smith CA $136 CA $151 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/c62bc9b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/815a509d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/90e33e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/4d4cc6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Saint George, SC – I-95 [](https://www.expedia.ca/St-George-Hotels-Knights-Inn-Saint-George.h6132858.Hotel-Information) St. George 6.6/10 (193 reviews) "The room is clean and a nice size ,water was hot for a nice relaxing shower.The bed is very comfortable Just wish had a coffee maker in room .very friendly check in .would definitely recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice CA $78 CA $87 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/St-George-Hotels-Knights-Inn-Saint-George.h6132858.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/666bcafd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/e5d82d39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/f02ed3ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/890000/889300/889204/e2987c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge St. George [](https://www.expedia.ca/St-George-Hotels-Econo-Lodge-St-George.h889204.Hotel-Information) St. George 6.4/10 (268 reviews) "It was nice all together " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia CA $80 CA $86 total includes taxes & fees Mar 20 - Mar 21 [](https://www.expedia.ca/St-George-Hotels-Econo-Lodge-St-George.h889204.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/b034ff09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/bc8b5a93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/efa2345e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peach Tree Inn [](https://www.expedia.ca/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) St. George 7.4/10 Good (171 reviews) "Clean rooms and pleasant staff. Could use newer towels. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia [](https://www.expedia.ca/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/d3f2bbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/27b2c420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11ccce69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn St George, SC [](https://www.expedia.ca/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) St. George 7.4/10 Good (659 reviews) "Breakfast was an overstatement!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicki CA $102 CA $113 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-21&endDate=2026-03-22®ionId=553248635974902828&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=HTG_SPRING_PROMO_553248635974902828) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWhetsell-Hotels.d553248635974902828.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWhetsell-Hotels.d553248635974902828.Travel-Guide-Hotels) ## Top Whetsell Hotel Reviews ## Recent Reviews in Whetsell ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516_y.jpg) ### Comfort Inn & Suites Santee 8/10 Good "The stay was good though not as good as other Comfort Inn and Suites. Room was very clean but toilet seat looked like it had come " [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3_y.jpg) ### Holiday Inn Santee by IHG 8/10 Good "Parking was easy. There are not many if any restaurants nearby. Some fast food places but I didn't explore much. My room was quiet and clean. Easy check-in and checkout. The lady at the desk was friendly. " [](https://expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26_y.jpg) ### Fairfield Inn by Marriott Orangeburg 8/10 Good "We stayed here in order to visit nearby Congaree National Park. Overall it was a good stay." [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 8/10 Good "Lovely staff who were very helpful " [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3_y.jpg) ### Best Western Plus Santee Inn 8/10 Good "Clean and comfortable ," [](https://expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Peach Tree Inn](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d_y.jpg) ### Peach Tree Inn 6/10 Okay "We had a quick overnight stay while traveling down I-95\. The front desk person seemed to have a little bit of an attitude, there were stains on the chairs in the room, the built-I. AC in the room wasn’t pleasant to look at (dirty/old). The included breakfast was lacking. There was only cereal and homemade waffles. It didn’t taste bad, but they didn’t haven’t butter out for it and they don’t have creamer for coffee, only milk. You typically get what you pay for, but I’m not sure if we would stay here again. " [](https://expedia.ca/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "It is conveniently located off I-95\. The property was clean. The staff was friendly and even gave us restaurant recommendations that we enjoyed." [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg) ### Baymont by Wyndham Santee 6/10 Okay "No hot water for shower, however, oddly the sink did have hot water. Perhaps the shower head was faulty." [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "Parking easy. Friendly, helpful staff. Quiet room with a comfortable bed. A good night’s sleep in a nice area." [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ## More cheap stays in Whetsell ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street Santee SC CA $109 CA $120 total Mar 8 - Mar 9 includes taxes & fees 8/10 Very Good! (1,442 reviews) [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Days Inn by Wyndham St George](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e088653f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham St George 139 Motel Dr St. George SC CA $136 CA $151 total Mar 8 - Mar 9 includes taxes & fees 7.6/10 Good! (1,003 reviews) [](https://expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites Santee 221 Britain St Santee SC CA $141 CA $156 total Mar 15 - Mar 16 includes taxes & fees 8/10 Very Good! (1,007 reviews) [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Santee Inn I 95 Exit 98 Santee SC CA $152 CA $169 total Mar 8 - Mar 9 includes taxes & fees 8.8/10 Excellent! (1,008 reviews) [](https://expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC CA $155 CA $172 total Mar 16 - Mar 17 includes taxes & fees 9.2/10 Wonderful! (750 reviews) [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Peach Tree Inn](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Peach Tree Inn 111 Conners Dr St. George SC [Get rates](https://expedia.ca/Hotel-Search?startDate=21%2F03%2F2026&endDate=22%2F03%2F2026&selected=2911319&PinnedHotelID=2911319&HadPinnedHotel=true®ionId=553248635974902828) 7.4/10 Good! (171 reviews) [](https://expedia.ca/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ## Hotels in Whetsell with star rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.ca/4Star-Whetsell-Hotels.s40-0-d553248635974902828.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 6 properties [](https://expedia.ca/3Star-Whetsell-Hotels.s30-0-d553248635974902828.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 41 properties [](https://expedia.ca/2Star-Whetsell-Hotels.s20-0-d553248635974902828.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Whetsell? > This district is the heart of Whetsell, known for its well-preserved 19th-century architecture and tree-lined streets. Main Street is where you'll find a good selection of independent shops, local eateries, and art galleries. Court Street, running parallel, features several historic homes and the county courthouse. The area is quite walkable, making it easy to explore on foot. > > > Couples often find the Historic District ideal for a relaxing getaway. You can enjoy strolls through the historic streets, dine at intimate restaurants, and visit local boutiques. The proximity to the Whetsell Riverfront Park offers pleasant views and walking paths great for an evening amble. > > > For business travellers, staying in the Historic District offers convenience and quality. Many of the town's professional services and government offices are located within or very close to this area. ### When is the best time to go to Whetsell? > During spring, you'll experience mild temperatures, typically ranging from 15°C to 25°C, with blooming flora adding to the scenic beauty. This is a great time for couples to enjoy strolls through the historic downtown area, perhaps along Main Street, where many local shops and eateries are located. The warmer but not overly hot weather is superb for exploring the nearby Whetsell Riverfront Park, which often hosts local events and provides lovely views. > > > Autumn also brings comfortable temperatures, generally between 18°C and 28°C, along with the beautiful changing colours of the leaves. This season is particularly appealing for solo travellers looking for a relaxed yet engaging visit. The cooler evenings are superb for dining al fresco at one of the many restaurants around the market square or simply enjoying a quiet walk. Nature enthusiasts will appreciate the comfortable conditions for hiking the trails in the Whetsell State Park, just a short drive from the town centre. > > > While the summer months (June to August) are warm and sunny, with temperatures often exceeding 30°C and high humidity, they can be quite hot for those not accustomed to it. Winter (November to March) is mild but can be a bit chilly, with occasional dips below freezing, making some outdoor activities less appealing. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Whetsell hotel booking with Expedia? ### How much is the nightly rate at a Whetsell hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Bamberg Hotels ](https://www.expedia.ca/Bamberg-Hotels.d55570.Travel-Guide-Hotels) - [B&B in Bowman ](https://www.expedia.ca/Bowman-Bed-And-Breakfast.d553248634998681915-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Red Roof Inn Hotels in Bowman ](https://www.expedia.ca/Bowman-Hotels-Red-Roof-Inn.0-0-d553248634998681915--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Bowman Hotels ](https://www.expedia.ca/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Cheap Hotels in Branchville ](https://www.expedia.ca/Branchville-Hotels-Cheap-Hotels.0-0-d3000455875-tCheapHotels.Travel-Guide-Filter-Hotels) - 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