Title: Book The Best Hotels in Vance, SC for 2026 from CA $88 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Vance](https://expedia.ca/Vance-Vacation-Rentals.d3000456153.Travel-Guide-VacationRentals)[Vance Car Rentals](https://expedia.ca/Car-Rentals-In-Vance.d3000456153.Car-Rental-Guide)[Vance Vacation Packages](https://expedia.ca/Vance.d3000456153.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Vance Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Vance%2C+South+Carolina%2C+United+States+of+America®ionId=3000456153&latLong=33.433774%2C-80.422866&adults=2&startDate=2026-02-05&d1=2026-02-05&endDate=2026-02-07&d2=2026-02-07&amenities=PETS) Pool [](https://www.expedia.ca/Hotel-Search?destination=Vance%2C+South+Carolina%2C+United+States+of+America®ionId=3000456153&latLong=33.433774%2C-80.422866&adults=2&startDate=2026-02-05&d1=2026-02-05&endDate=2026-02-07&d2=2026-02-07&amenities=POOL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Vance%2C+South+Carolina%2C+United+States+of+America®ionId=3000456153&latLong=33.433774%2C-80.422866&adults=2&startDate=2026-02-05&d1=2026-02-05&endDate=2026-02-07&d2=2026-02-07&travelerType=family_friendly) Condo [](https://www.expedia.ca/Hotel-Search?destination=Vance%2C+South+Carolina%2C+United+States+of+America®ionId=3000456153&latLong=33.433774%2C-80.422866&adults=2&startDate=2026-02-05&d1=2026-02-05&endDate=2026-02-07&d2=2026-02-07&lodging=CONDO) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Vance%2C+South+Carolina%2C+United+States+of+America®ionId=3000456153&latLong=33.433774%2C-80.422866&adults=2&startDate=2026-02-05&d1=2026-02-05&endDate=2026-02-07&d2=2026-02-07&lodging=COTTAGE) ## Check prices for these dates Tonight [Jan 22 - Jan 23](https://www.expedia.ca/Hotel-Search?regionId=3000456153&startDate=2026-01-22&endDate=2026-01-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=3000456153&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=3000456153&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=3000456153&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Vance hotels ![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/b0419165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/ee0f57db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bells Marina & Resort [](https://www.expedia.ca/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) Eutawville 8.6/10 Excellent (86 reviews) "Super quaint, quiet, nice little get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $131 CA $145 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/e17744ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/515ae417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/ad05322a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109320000/109319000/109318932/a22ac41a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Budget Inn By Belvilla St George I-95 [](https://www.expedia.ca/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) St. George 7.6/10 Good (170 reviews) "This is a great value for a budget hotel. It's an older complex but clean and well maintained. It's close to decent food options for tired travelers and the front desk staff was pleasant and helpful. If you are looking for a convient, well priced stopover, I recommend this location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim [](https://www.expedia.ca/Reevesville-Hotels-Budget-Inn-St-George-I-95.h109318932.Hotel-Information) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e088653f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/a66aad1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e85d0e8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham St George [](https://www.expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) St. George 7.6/10 Good (1,000 reviews) "Clean, relaxing, friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Smith CA $120 CA $134 total includes taxes & fees Jan 23 - Jan 24 [](https://www.expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/1ffbf2b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) Santee 9.6/10 Exceptional (1,001 reviews) "Liked the size of the room, the staff and the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virginia CA $172 CA $190 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5ef3d5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/6fa02d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very good (989 reviews) "Very good" ![China](https://a.travel-assets.com/egds/marks/flags/cn.svg) Wendeng CA $155 CA $172 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/d654e116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1,000 reviews) "Clean spacious room, nice amenities and good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $167 CA $186 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/4686cd8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/9e846421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/5b49de0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee [](https://www.expedia.ca/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) Santee 6.6/10 (642 reviews) "A good option if traveling with pets. The hotel is clean and well maintained but dated. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $90 CA $100 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/d34bd120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/13247169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/2def81ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Santee I-95 [](https://www.expedia.ca/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) Santee 6.4/10 (548 reviews) "The grounds and property were clean and you could tell they take pride in what they're offering." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $84 CA $93 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/0b55a618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very good (1,006 reviews) "Clean rooms, nice staff, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale CA $142 CA $158 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/dc3438b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2262fc91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) Santee 6.8/10 (441 reviews) "The staff was very friendly and helpful. Room was clean and beds were so comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy CA $104 CA $115 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/4c792a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/e77a8624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee I-95 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) Santee 6.0/10 (467 reviews) "Most importantly room was clean. Check in was good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marjan CA $75 CA $91 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ec6d0d77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/044c704d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/67da47be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1,001 reviews) "Nuce, clean room, pleasant staff. Convenient access for overnight stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wayne CA $165 CA $183 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/3a41c72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/efa2345e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/b034ff09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peach Tree Inn [](https://www.expedia.ca/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) St. George 7.4/10 Good (154 reviews) "Clean rooms and pleasant staff. Could use newer towels. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $93 CA $101 total includes taxes & fees Jan 23 - Jan 24 [](https://www.expedia.ca/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/6c8567ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/0af71c77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/51caeaed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/7dca4a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Santee [](https://www.expedia.ca/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) Santee 6.4/10 (310 reviews) "Last minute arrangements stay was quiet and peaceful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iasia CA $87 CA $97 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/w2876h2156x4y4-cb52be76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/cbf250f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/9e537497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6140000/6132900/6132858/4d4cc6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Saint George, SC – I-95 [](https://www.expedia.ca/St-George-Hotels-Knights-Inn-Saint-George.h6132858.Hotel-Information) St. George 6.6/10 (186 reviews) "The room is clean and a nice size ,water was hot for a nice relaxing shower.The bed is very comfortable Just wish had a coffee maker in room .very friendly check in .would definitely recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice CA $80 CA $88 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/St-George-Hotels-Knights-Inn-Saint-George.h6132858.Hotel-Information) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/5b7ee831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Santee 7.0/10 Good (688 reviews) "Nice quiet room and a delicious breakfast at a reasonable rate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph B CA $86 CA $95 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1,415 reviews) "Always a great stay. Clean room, friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $104 CA $115 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11093b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/d3f2bbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/27b2c420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn St George, SC [](https://www.expedia.ca/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) St. George 7.4/10 Good (647 reviews) "Great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Swetlana CA $92 CA $102 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/40f69ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) Santee 9.2/10 Wonderful (693 reviews) "Stay was great felt so welcomed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesse CA $148 CA $164 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![1 bedroom](https://images.trvl-media.com/lodging/38000000/37990000/37985500/37985493/6d344ac6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom](https://images.trvl-media.com/lodging/38000000/37990000/37985500/37985493/2e74c3af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom](https://images.trvl-media.com/lodging/38000000/37990000/37985500/37985493/939e2a74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/38000000/37990000/37985500/37985493/409142e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Starlight Stays [](https://www.expedia.ca/Manning-Hotels-OYO-Hotel-Manning-SC.h37985493.Hotel-Information) Manning 7.0/10 Good (7 reviews) "It was nice for the area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kendrell CA $80 CA $89 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Manning-Hotels-OYO-Hotel-Manning-SC.h37985493.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-05&endDate=2026-02-06®ionId=3000456153&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FVance-Hotels.d3000456153.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FVance-Hotels.d3000456153.Travel-Guide-Hotels) ## Learn more about Vance Head to sights like Lake Marion as you discover the local area in Vance. [See all hotels in Vance](https://www.expedia.ca/Hotel-Search?startDate=2026-02-05&endDate=2026-02-06&adults=2®ionId=3000456153) ![Aerial of Lake Marion Dam and Santee river in South Carolina providing drinking water, hydro power and recreational activities](https://images.trvl-media.com/place/3000456153/853d0648-5ca3-4a52-8d03-1e972c294c7d.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## More cheap stays in Vance ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street Santee SC CA $104 CA $115 total Jan 26 - Jan 27 includes taxes & fees 7.8/10 Good! (1,424 reviews) [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn by Marriott Orangeburg 663 Citadel Road Orangeburg SC CA $116 CA $129 total Feb 10 - Feb 11 includes taxes & fees 8.2/10 Very Good! (711 reviews) [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Days Inn by Wyndham St George](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham St George 139 Motel Dr St. George SC CA $120 CA $134 total Jan 23 - Jan 24 includes taxes & fees 7.4/10 Good! (1,004 reviews) [](https://expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC CA $148 CA $164 total Feb 2 - Feb 3 includes taxes & fees 9.2/10 Wonderful! (683 reviews) [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Santee 9074 Old Number Six Hwy Santee SC CA $167 CA $186 total Feb 2 - Feb 3 includes taxes & fees 9.6/10 Exceptional! (1,006 reviews) [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Santee-I-95 9060 Old Number Six Hwy Santee SC CA $172 CA $190 total Feb 9 - Feb 10 includes taxes & fees 9.6/10 Exceptional! (1,005 reviews) [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ## Hotels in Vance with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.ca/4Star-Vance-Hotels.s40-0-d3000456153.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 8 properties [](https://expedia.ca/3Star-Vance-Hotels.s30-0-d3000456153.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 49 properties [](https://expedia.ca/2Star-Vance-Hotels.s20-0-d3000456153.Travel-Guide-Filter-Hotels) ## Recent reviews of Vance hotels ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 5/5 Excellent "Check in courteous and efficient, Room was clean with plenty of space, breakfast was good" A verified traveller stayed at Fairfield Inn & Suites by Marriott Santee Posted 3 days ago [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 5/5 Excellent "Very nice! Very friendly check in, great beds & shower, very clean. Easy to reach from I 95." A verified traveller stayed at Tru By Hilton Santee Posted 5 days ago [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e_y.jpg) ### Comfort Inn & Suites Santee 5/5 Excellent "Staff was very friendly and the room was large and very clean. " A verified traveller stayed at Comfort Inn & Suites Santee Posted 5 days ago [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 5/5 Excellent "The room is elegant" A verified traveller stayed at Hampton Inn Santee-I-95 Posted 7 days ago [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 5/5 Excellent "The outside of the building is nothing to look at, but the room was modern, clean, had good bathrooms, was spacious. Had a larger refrigerator and a microwave. Very comfortable for an overnight stay. The price was great too" A verified traveller stayed at Baymont by Wyndham Santee Posted 7 days ago [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 5/5 Excellent "Some recent updates are much appreciated. Staff is always very nice. The grounds and the room are very clean." A verified traveller stayed at Best Western Plus Santee Inn Posted 7 days ago [](https://expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27_y.jpg) ### Fairfield Inn by Marriott Orangeburg 5/5 Excellent "The room was nice " A verified traveller stayed at Fairfield Inn by Marriott Orangeburg Posted 7 days ago [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Days Inn by Wyndham St George](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd_y.jpg) ### Days Inn by Wyndham St George 5/5 Excellent "Clean room " A verified traveller stayed at Days Inn by Wyndham St George Posted 10 days ago [](https://expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Peach Tree Inn](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/3a41c72c_y.jpg) ### Peach Tree Inn 5/5 Excellent "Nice" A verified traveller stayed at Peach Tree Inn Posted 12 days ago [](https://expedia.ca/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ## Frequently asked questions ### When is the best time to go to Vance? > As you delve into the peak season, which spans from March to May, you'll find that this is an ideal time for tourists who enjoy engaging with the local culture and history. The streets of Vance are bustling with life, and you can partake in various events and festivals that showcase the city's rich heritage. This lively atmosphere allows for a wonderful blend of leisurely strolls and cultural immersion. > > > For those who appreciate a more serene experience, February offers a quieter alternative. While the temperatures may dip between 3 to 10°C, this month can provide unique opportunities to witness the charm of Vance without the crowds. Plus, you might find some great deals on accommodations and attractions, ensuring good value for your travel budget. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Vance hotel booking with Expedia? ### How much is the nightly rate at a Vance hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [Alcolu Hotels ](https://www.expedia.ca/Alcolu-Hotels.d3000422483.Travel-Guide-Hotels) - [B&B in Bowman ](https://www.expedia.ca/Bowman-Bed-And-Breakfast.d553248634998681915-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Red Roof Inn Hotels in Bowman ](https://www.expedia.ca/Bowman-Hotels-Red-Roof-Inn.0-0-d553248634998681915--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Bowman Hotels ](https://www.expedia.ca/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Branchville Hotels ](https://www.expedia.ca/Branchville-Hotels.d3000455875.Travel-Guide-Hotels) - [Farmstay in Cameron ](https://www.expedia.ca/Cameron-Agritourism.d553248634998916920-aaAgritourism.Travel-Guide-Accommodation) - 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