Texas Medical Center Vacation Packages

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    Save up to CA $1,096 when you book a flight and hotel together*

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Top Holiday Package Deals in Texas Medical Center

Price found within the past 48 hours. Click for updated prices.
Palace Inn Blue Edgebrook

Palace Inn Blue Edgebrook

3 out of 5
Southeast Houston
Price was CA $765, price is now CA $589 per person
CA $589
per person
Apr 25 - Apr 29
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Houston (IAH)
9.4/10 Exceptional! (142 reviews)
The breakfast was packed muffins, waffles, cereal, no hot breakfast at all.

Reviewed on Jan 10, 2026

The Lancaster Hotel

The Lancaster Hotel

4 out of 5
Downtown Houston
Price was CA $2,857, price is now CA $2,002 per person
CA $2,002
per person
May 3 - May 8
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Houston (IAH)
9.8/10 Exceptional! (1,004 reviews)
Room was good and people were nice however breakfast was inedible really really bad. Juice in the room fridge was also spoiled. This place is very closer to the theatre which we like but the amenities were certainly not in line with the price. Should also note that it took three separate calls to book a room and then they quoted 40 dollars more than Expedia. When I asked about the difference I was just repeated the rate quoted before. We have stayed here multiple times but next time I think we will go to one of the Marriotts or even the Hilton 😞shame because the rooms are nice and the location is excellent.

Reviewed on Feb 16, 2026

Hotel Saint Augustine

Hotel Saint Augustine

3.5 out of 5
Montrose
Price was CA $2,112, price is now CA $1,485 per person
CA $1,485
per person
May 3 - May 8
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Houston (IAH)
9.8/10 Exceptional! (56 reviews)
I did not have breakfast.

Reviewed on Jan 12, 2026

Hampton Inn & Suites Houston Heights I-10

Hampton Inn & Suites Houston Heights I-10

2.5 out of 5
Washington Ave./ Memorial Park
Price was CA $1,300, price is now CA $916 per person
CA $916
per person
Apr 15 - Apr 20
found 20 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Houston (IAH)
9/10 Wonderful! (1,003 reviews)
Stay was great, had no issues. Continental breakfast was also very good.

Reviewed on Feb 20, 2026

ECLIPZ Modern CEO Corp House

ECLIPZ Modern CEO Corp House

5 out of 5
Price was CA $4,678, price is now CA $3,560 per person
CA $3,560
per person
Mar 23 - Mar 28
found 14 hours ago
Roundtrip flight included
Calgary (YYC) to Houston (IAH)
No reviews

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Discovery Green which includes city views, a square or plaza and a skyscraper

Downtown Houston

3 out of top 10 points of interest in this area
4/5(79 area reviews)

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Find hotels in Downtown Houston

Texas Medical Center Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
The price is CA $259 per night from Feb 22 to Feb 23
CA $259
CA $303 total
Feb 22 - Feb 23
includes taxes & fees
9/10 Wonderful! (3,751 reviews)
The room was spacious. The evening staff was unfriendly and room have clean only had 2 big towels aand calling front desk was impossible. Text them requesting towel set afte check in never received them

Reviewed on Feb 21, 2026

Blossom Hotel Houston, Curio Collection by Hilton
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is CA $240 per night from Feb 22 to Feb 23
CA $240
CA $298 total
Feb 22 - Feb 23
includes taxes & fees
9.2/10 Wonderful! (1,117 reviews)
Everything above!

Reviewed on Feb 20, 2026

The Westin Houston Medical Center/Museum District
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $190 per night from Feb 22 to Feb 23
CA $190
CA $224 total
Feb 22 - Feb 23
includes taxes & fees
9.2/10 Wonderful! (2,368 reviews)
Yes No microwave in room.

Reviewed on Feb 21, 2026

Hyatt Place Houston Medical Center
See all 6,568 properties in Texas Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
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Family Vacations

Frequently asked questions

How much does a Texas Medical Center vacation package cost?
Much less than you might think — from only CA $589, in fact! By bundling flights, hotels and car rentals into a tailor-made vacation package, your getaway to Texas Medical Center is just a few clicks away.
How do I get a cheap travel package to Texas Medical Center?
Browse and lock in everything in the one place with our Texas Medical Center vacation packages. You'll discover bargains on flights, hotels, tours and more that'll keep your hip pocket happy and your adventurous spirit alive. And, with more than 550 airlines and 1,000,000 properties all over the world to select from, you'll have the flexibility to mix and match as you please.
Where should I stay in Texas Medical Center?
Choose a place close to Houston Zoo. This famous sight is in the middle of the action and on the must-see lists of many travelers.
What are the top hotels in Texas Medical Center?
Hilton Garden Inn Houston Medical Center, TX and Home2 Suites by Hilton Houston Medical Center, TX are two of the most well-known hotels in Texas Medical Center. Why not have a look at the rates and amenities at each and then decide?
How far in advance should I book my Texas Medical Center vacation?
Browse Expedia to compare international flights as soon as you know your travel dates. You can normally purchase a ticket up to a year in advance. If it's too early for your preferred air carrier, or you have to book last minute, don't stress. Low prices to Texas Medical Center occasionally appear just weeks before the date of departure.
What does an Expedia Texas Medical Center travel package include?
Expedia has all you need to lock in Texas Medical Center trip, but how your package is structured is your choice. Choose from a combination of rental cars, flights and hotels. In search of a few activities to keep you busy? Once you've made your booking, you can add them too. Whatever your style or budget, there's a package deal to match your needs.
What should I know before booking a Texas Medical Center travel package?
Our prices are already low. However, you'll snap up even more savings when you book your flights, hotels and car rentals together. With an Expedia travel package, you'll get transparent pricing and a terrific range of choice.
Can I choose my airline with a Texas Medical Center Expedia vacation package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines around the world. Our packages give you the flexibility to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Texas Medical Center vacation package?
It's difficult to predict what tomorrow might bring, so it's good to know that you can change or cancel your Texas Medical Center vacation package. If you made your booking in the last 24 hours, you may be eligible for a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to learn more.

Discover the most popular places to visit in Texas Medical Center

MD Anderson Cancer Center

Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.

MD Anderson Cancer Center

Things to do

The Official Houston City Tour

NASA's Space Center Admission Plus Houston City Tour

CA $149
per adult
92% of travellers recommend
NASA's Space Center Admission Plus Houston City Tour
Astroville Tunnel Tour of Downtown Houston

Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)

CA $34
per adult
100% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
Houston: Houston Botanic Garden Entry Ticket

Houston: Houston Botanic Garden Entry Ticket

CA $16
per adult
80% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
See all activities in Houston
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.