A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

St. Charles Vacation Rentals

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Our top choices for St. Charles vacation rentals

1. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (183 reviews)
"Great place to stay. Our go to when visiting St.Charles or STL"
United States
jeramy p.
The price is CA $174
CA $363 total
includes taxes & fees
Aug 16 - Aug 17
The Lofts of North Main Street

2. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (37 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is CA $151
CA $325 total
includes taxes & fees
Aug 16 - Aug 17
Historic Main Street Studio | Dog-Friendly

3. St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (161 reviews)
"Very nice historical place "
United States
Shawntell C.
The price is CA $182
CA $390 total
includes taxes & fees
Aug 12 - Aug 13
St. Charles 1860's Gem - Sleeps 6!

4. Cottage on Historic Main Street- Low Cleaning fee

Cottage on Historic Main Street- Low Cleaning fee
St. Charles Historic District
10.0 out of 10, Exceptional, (20 reviews)
"Great location to Main Street. "
United States
Daneen H.
The price is CA $146
CA $389 total
includes taxes & fees
Aug 13 - Aug 14
Cottage on Historic Main Street- Low Cleaning fee

5. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (116 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveller
The price is CA $174
CA $364 total
includes taxes & fees
Aug 13 - Aug 14
Prime Loft of Main Street

6. Cottage on Main st- Low Cleaning Fee

Cottage on Main st- Low Cleaning Fee
St. Charles Historic District
10.0 out of 10, Exceptional, (9 reviews)
"Good location. Decorated very nicely. "
United States
Debbie A.
The price is CA $158
CA $403 total
includes taxes & fees
Aug 25 - Aug 26
Cottage on Main st- Low Cleaning Fee

7. Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
St. Charles Historic District
9.6 out of 10, Exceptional, (80 reviews)
"Quaint and quiet, with easy access to downtown St Charles."
United States
Jeffrey E.
The price is CA $174
CA $355 total
includes taxes & fees
Aug 25 - Aug 26
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

8. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (67 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is CA $174
CA $364 total
includes taxes & fees
Aug 13 - Aug 14
Amazing Renovated Historic Loft on Main Street

9. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (25 reviews)
"Great location"
United States
todd p.
The price is CA $188
CA $400 total
includes taxes & fees
Aug 24 - Aug 25
Pet-Friendly Duplex | Historic Main

10. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
The price is CA $138
CA $398 total
includes taxes & fees
Aug 13 - Aug 14
6th street 101 - Walk to Main St

11. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is CA $188
CA $503 total
includes taxes & fees
Aug 18 - Aug 19
Historic Main St. Customs House Upstairs Apartment

12. 5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1

5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
St. Charles Historic District
8.8 out of 10, Excellent, (15 reviews)
"House was beautiful. Very nice quiet stay"
United States
Amy S.
The price is CA $138
CA $352 total
includes taxes & fees
Aug 16 - Aug 17
5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1

13. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is CA $138
CA $351 total
includes taxes & fees
Aug 13 - Aug 14
1st Capitol Mansion - Suite 401

14. Near Streets of St Charles | 2 King Beds

Near Streets of St Charles | 2 King Beds
Saint Charles
9.0 out of 10, Wonderful, (12 reviews)
"We really enjoyed our stay. The house was clean, spacious, and very accommodating. We stayed for a dance competition and the proximity to the convention center was unbeatable. "
United States
Chloe
The price is CA $158
CA $431 total
includes taxes & fees
Aug 24 - Aug 25
Near Streets of St Charles | 2 King Beds

15. Historic 1908 Frenchtown Home

Historic 1908 Frenchtown Home
St. Charles Historic District
8.6 out of 10, Excellent, (25 reviews)
"yes the kitchen was fully equipped."
Canada
David M.
The price is CA $188
CA $458 total
includes taxes & fees
Aug 23 - Aug 24
Historic 1908 Frenchtown Home

16. Dog-Friendly 2BR | Near Streets of St Charles

Dog-Friendly 2BR | Near Streets of St Charles
Saint Charles
9.0 out of 10, Wonderful, (19 reviews)
"Wish we would have had more time to stay a little longer. Will definitely stay again in the future!"
United States
Rebecca O.
The price is CA $166
CA $439 total
includes taxes & fees
Aug 16 - Aug 17
Dog-Friendly 2BR | Near Streets of St Charles

17. HotTub-2br2b-near Historic Main Street

HotTub-2br2b-near Historic Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (15 reviews)
"Easy check in, very clean, great location. Amazing hot tub! Perfect for a girl's weekend!"
United States
Kara A.
The price is CA $238
CA $458 total
includes taxes & fees
Aug 18 - Aug 19
HotTub-2br2b-near Historic Main Street

18. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
9.8 out of 10, Exceptional, (8 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is CA $226
CA $448 total
includes taxes & fees
Aug 16 - Aug 17
Walk to Main | Pet-Friendly Yard & Workspace

19. Stunning 1890's Home - Sleeps 8!

Stunning 1890's Home - Sleeps 8!
St. Charles Historic District
10.0 out of 10, Exceptional, (131 reviews)
"Super cute property, fantastic location. Very well maintained and clean, would definitely stay here again. "
United States
Jason T.
The price is CA $251
CA $558 total
includes taxes & fees
Aug 24 - Aug 25
Stunning 1890's Home - Sleeps 8!

20. Driftwood Den | Boho 2BR | Dog-Friendly

Driftwood Den | Boho 2BR | Dog-Friendly
St. Charles Historic District
10.0 out of 10, Exceptional, (4 reviews)
"Loved our stay here. Clean, comfortable, convenient. Couldn’t have been easier, in all aspects. Already plan to stay there again!!!"
United States
Kourtney S.
The price is CA $181
CA $447 total
includes taxes & fees
Aug 23 - Aug 24
Driftwood Den | Boho 2BR | Dog-Friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Find out more about St. Charles

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with St. Charles. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, you can find vacation rentals near popular attractions in St. Charles, or you can choose a secluded option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theater scene are some other things you might like to check out during your trip.

What are some of the best vacation rentals that St. Charles has to offer?

St. Charles 1860's Gem - Sleeps 6!: This St. Charles vacation home rental is located on a river and has a garden, a selection of books, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Some other top choices in St. Charles are The St. Charles Guest House, lovely historic home, fun for families and groups and 🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟.

How many vacation rentals are there in St. Charles?

Expedia has 84 vacation rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and Frontier Park.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned accommodations you can book for several days or more in St. Charles. Vacation rentals provide amenities such as laundry facilities and kitchens to help you enjoy your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for a family getaway.