Santa Rosa Vacation Rentals

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Our top choices for Santa Rosa vacation rentals

Charming cottage with 2 separate beds and a beautiful view of the river

Charming cottage with 2 separate beds and a beautiful view of the river
Santa Rosa
10.0 out of 10, Exceptional, (1 review)
"Wir fanden die Unterkunft aufgrund der guten Wegbeschreibung sofort. Die Empfang war sehr nett. Das Haus war sehr sehr sauber und wir haben uns sehr wohl gefühlt. Alles war perfekt. Es war die sauberste/beste Unterkunft die wir bei unserer Panama Rundtour in Panama hatte. Erik und Alba alles Gute und vielen Dank."
Germany
Birgit U.
The price is CA $172
CA $200 total
includes taxes & fees
May 11 - May 12
Charming cottage with 2 separate beds and a beautiful view of the river

Panama View House – A Hilltop Retreat with Stunning Canal Views

Panama View House – A Hilltop Retreat with Stunning Canal Views
Panama City
The price is CA $49
CA $111 total
includes taxes & fees
May 11 - May 12
Panama View House – A Hilltop Retreat with Stunning Canal Views

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (193 reviews)
"Nice place, convenient and nicely priced"
United States
Camille L
The price is CA $68
CA $266 total
includes taxes & fees
May 13 - May 14
Boutique Apartments Panamá Coco del Mar

LILIA HOUSE 10 MINUTES AIRPORT

LILIA HOUSE 10 MINUTES AIRPORT
Panamá
8.0 out of 10, Very good, (1 review)
The price is CA $62
CA $108 total
includes taxes & fees
May 16 - May 17
LILIA HOUSE 10 MINUTES AIRPORT

Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
7.8 out of 10, Good, (291 reviews)
"Inhouse laundry service was very useful. Shops and restaurants nearby."
United States
Dustin
The price is CA $50
CA $205 total
includes taxes & fees
May 21 - May 22
Boutique Apartments Panama

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (548 reviews)
"Nice clean room..and good breakfast"
United States
GEORGE
The price is CA $127
CA $139 total
includes taxes & fees
May 12 - May 13
Torres de Alba Hotel & Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.2 out of 10, Wonderful, (285 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is CA $164
CA $253 total
includes taxes & fees
May 14 - May 15
Arcadia Condo Suites

w* | Refined 1BR in Casco Antiguo

w* | Refined 1BR in Casco Antiguo
Casco Viejo
10.0 out of 10, Exceptional, (3 reviews)
"It’s very good for solo traveler. Juan is a great host and responds very quickly. Great location in the old city."
United States
Dongmei
The price is CA $59
CA $100 total
includes taxes & fees
May 17 - May 18
w* | Refined 1BR in Casco Antiguo

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.0 out of 10, Very good, (94 reviews)
"Friendly staff "
United States
Charles
The price is CA $88
CA $287 total
includes taxes & fees
May 11 - May 12
Yoo Panamá by Boutique Apartments

Centrally located 2 bedroom apartment

Centrally located 2 bedroom apartment
San Francisco
10.0 out of 10, Exceptional, (1 review)
"Maria was responsive. Her apartment was spacious and accommodating "
United States
Karyn W.
The price is CA $88
CA $176 total
includes taxes & fees
May 12 - May 13
Centrally located 2 bedroom apartment

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
8.0 out of 10, Very good, (1 review)
"Review checkin process. Find entry codes and details about key fobs. Find out if there is construction next door as i was awaken every morning at 7am by construction noise. Verify everything works upon entry and request immediate fix. I was without internet for a day and had to wait various days for repairmen to come fix things without having a set time for their visit. Great place to stay. Walking distance of many things and great amenities but had some minor inconveniences. Staff was very...
United States
Will
The price is CA $62
CA $279 total
includes taxes & fees
May 14 - May 15
Living 73 Panamá by Boutique Apartments

La Moderna by Wynwood House

La Moderna by Wynwood House
3.0 star property
Casco Viejo
7.4 out of 10, Good, (45 reviews)
"Super easy self checkin and check out. Great location. Very nice and spacious place."
United States
Robyn
The price is CA $76
CA $128 total
includes taxes & fees
May 17 - May 18
La Moderna by Wynwood House

Central Apartment with Balcony | Casco Viejo | M1

Central Apartment with Balcony | Casco Viejo | M1
Casco Viejo
9.2 out of 10, Wonderful, (5 reviews)
"The room was absolutely clean and wonderful, but the spa was under construction until the last day"
United States
Jeremiah T.
The price is CA $78
CA $161 total
includes taxes & fees
May 25 - May 26
Central Apartment with Balcony | Casco Viejo | M1

La Palma Experience

La Palma Experience
3.0 star property
Amador
8.4 out of 10, Very good, (8 reviews)
"Air conditioner has good working. People are nice and good response for us. Basically room are clean but I can see small ants some of them on the table and on floor. I doesn't matter for it. In neighbor restaurant made big sounds at night to midnight."
Japan
Shuntaro
The price is CA $89
CA $98 total
includes taxes & fees
May 11 - May 12
La Palma Experience

w* | Sunny Loft in Plaza Catedral

w* | Sunny Loft in Plaza Catedral
Casco Viejo
9.0 out of 10, Wonderful, (4 reviews)
"The room is spotless and the host is very courteous, responsive and helpful. Location is super convenient for us staying Old Town, so many museums and cathedrals are within walking distance. Night music on the street after 11 pm is a little noisy, but the host provides ear plugs, which make our sleep easier. "
United States
James
The price is CA $78
CA $153 total
includes taxes & fees
May 24 - May 25
w* | Sunny Loft in Plaza Catedral

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (189 reviews)
"Our stay at Las Clementines was beyond compare! We chose it due to its wonderful location in Casco Antigua, but it was so much more. The staff was incredibly helpful and kind. Marcos told us the history of the hotel and took time to show us the details that make this place so wonderful. Mahalo, the restaurant, on the main floor makes absolutely delicious food...try the ceviche for sure. Overall, this was a highlight of our 8 day trip."
United States
Shelley
The price is CA $174
CA $192 total
includes taxes & fees
May 14 - May 15
Las Clementinas

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Casco Viejo
9.8 out of 10, Exceptional, (6 reviews)
"Perfect location "
Canada
Mark D.
The price is CA $76
CA $159 total
includes taxes & fees
May 27 - May 28
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Casa Love by Wynwood House

Casa Love by Wynwood House
3.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (24 reviews)
"Super "
France
Stephen
The price is CA $105
CA $154 total
includes taxes & fees
May 12 - May 13
Casa Love by Wynwood House

w Bright 1BR w Private Balcony in San Francisco

w Bright 1BR w Private Balcony in San Francisco
2.0 star property
San Francisco
The price is CA $145
CA $204 total
includes taxes & fees
May 12 - May 13
w Bright 1BR w Private Balcony in San Francisco

Duplex with pool in front of national theater D6

Duplex with pool in front of national theater D6
Casco Viejo
9.0 out of 10, Wonderful, (6 reviews)
"Beautiful place, loved the pool and the closeness to Casco Viejo. 5 stars, highly recommend, would stay here again!"
United States
Danielle G.
The price is CA $97
CA $182 total
includes taxes & fees
May 20 - May 21
Duplex with pool in front of national theater D6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Rosa Hotel Reviews

Find out more about Santa Rosa

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Rosa. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there vacation rentals in Santa Rosa?

Yes, we have vacation rentals close to well known points of interest in Santa Rosa, or you can select a more remote option if you're looking for relaxation.

What are some of the best vacation rentals in Santa Rosa?

Oasis with pool near panama canal: Visitors like this Santa Rosa vacation home rental. It offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind.

What can I see and do in Santa Rosa?

Explore the area and family-friendly sights such as Summit Botanical Gardens & Zoo, or get out into nature at a spot like Chagres River. Albrook Shopping Mall and Gamboa Rainforest Resort are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Rosa?

Vacation rentals are privately owned properties you can stay in for a long or short time in Santa Rosa. Vacation rentals offer extras such as laundry facilities and kitchens so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of security away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive option for a family trip or a small group gathering.