Santa María Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Ready to book your vacation to Santa María?

 

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Santa María Hotel Deals

Gran Melia Iguazú

Gran Melia Iguazú

5 out of 5
Parque Nacional Iguazu Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
The price is CA $1,054 per night from Dec 6 to Dec 7
CA $1,054
CA $1,066 total
Dec 6 - Dec 7
9.4/10 Exceptional! (1,000 reviews)
"Everything was great. Specially feeling like being in middle of wilderness"

Reviewed on Nov 5, 2026

Gran Melia Iguazú
Hotel Saint George

Hotel Saint George

4 out of 5
Avenida Cordoba 148 Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
The price is CA $176 per night from Nov 12 to Nov 13
CA $176
CA $186 total
Nov 12 - Nov 13
9/10 Wonderful! (1,007 reviews)
"Limpio, muy céntrico. Y muchas facilidades. Desayuno excelente"

Reviewed on Nov 9, 2026

Hotel Saint George
Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

5 out of 5
Selva Iriapu Sin Numero Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
The price is CA $471 per night from Nov 24 to Nov 25
CA $471
CA $484 total
Nov 24 - Nov 25
9.2/10 Wonderful! (1,003 reviews)
"Everything was nice about the property. The location was a little further than we liked."

Reviewed on Nov 6, 2026

Loi Suites Iguazú Hotel
See all 405 properties in Misiones Province
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Santa María vacation package cost?
You can pick up a vacation package to this popular destination on Expedia. But how much your vacation to Santa María costs will depend on the season, length of stay and hotel choice.
What are the cheapest months to go to Santa María?
You can typically find lower prices and greater availability in April, May and June. Browse our cheap Santa María vacation packages and you could get some great off-season deals.
How many days is enough for Santa María?
Generally, a handful of days is enough to explore the major sights during your Santa María vacation. But if you prefer to have more time to rest or go on day tours, think about extending your itinerary.
How to find the best Santa María package deals?
Begin your search for a Santa María package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Santa María package deal right away, simply change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Marían escape underway.
Is it cheaper to book a Santa María vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll usually snag a better deal than booking each component individually. And you'll still get the flexibility to create a customized Santa María vacation by choosing your favourite accommodation type, airline and car class.
When to book a vacation package to Santa María?
If you have your Santa María travel dates locked in, book early to grab some incredible deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for setting off on a whim.
How to plan a trip to Santa María?

  1. Choose your travel dates: What you want to do in Santa Marían and your preferred season can help you decide when to get away.
  2. Work out your budget: Ensure you have enough money to cover everything from transportation and food to activities and flights. Your hotel will probably be the largest expense during your trip to Santa María.
  3. Determine how many days away: Start by listing all the activities and attractions you'd like to get to in Santa María. Then, estimate how long you'll need for each, as well as any travel time.
  4. Bundle your flights and hotel: Awesome destination, check. Length of stay, check. All that's left is to find a Santa María vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.