Santa María Vacation Packages

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    Save up to CA $1,096 when you book a flight and hotel together*
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Ready to book your vacation to Santa María?

 

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Santa María Hotel Deals

Hotel Saint George

Hotel Saint George

4 out of 5
Avenida Cordoba 148, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
The price is CA $122 per night from Sep 7 to Sep 8
CA $122
CA $122 total
Sep 7 - Sep 8
Hotel Saint George
Gran Melia Iguazú

Gran Melia Iguazú

5 out of 5
Parque Nacional Iguazu, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
The price is CA $799 per night from Sep 1 to Sep 2
CA $799
CA $799 total
Sep 1 - Sep 2
9/10 Wonderful! (1,000 reviews)
"My stay was very enjoyable and the service and attentiveness from the staff was amazing. The convenience of being right by the paths and within the park made it worth it."

Reviewed on Aug. 3, 2025

Gran Melia Iguazú
Mercure Iguazu Hotel Iru

Mercure Iguazu Hotel Iru

4.5 out of 5
Selva Iryapu S N - Predio 600 Has, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
The price is CA $225 per night from Sep 4 to Sep 5
CA $225
CA $225 total
Sep 4 - Sep 5
9/10 Wonderful! (509 reviews)
"Top-shelf room and property that exudes class but be warned - the hotel is not within walking distance of downtown except in dire need. Going anywhere will necessitate hiring a driver. Pool and jacuzzi were cold and unusable during my stay."

Reviewed on Jul. 12, 2025

Mercure Iguazu Hotel Iru
See all 375 properties in Misiones Province
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
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Frequently asked questions

How much does a Santa María vacation package cost?
You can pick up a vacation package to this popular destination on Expedia. But how much your vacation to Santa María costs will depend on the season, length of stay and hotel choice.
What are the cheapest months to go to Santa María?
You can typically find lower prices and greater availability in April, May and June. Browse our cheap Santa María vacation packages and you could get some great off-season deals.
How many days is enough for Santa María?
Generally, a handful of days is enough to explore the major sights during your Santa María vacation. But if you prefer to have more time to rest or go on day tours, think about extending your itinerary.
How to find the best Santa María package deals?
Begin your search for a Santa María package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Santa María package deal right away, simply change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Marían escape underway.
Is it cheaper to book a Santa María vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll usually snag a better deal than booking each component individually. And you'll still get the flexibility to create a customized Santa María vacation by choosing your favourite accommodation type, airline and car class.
When to book a vacation package to Santa María?
If you have your Santa María travel dates locked in, book early to grab some incredible deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for setting off on a whim.
How to plan a trip to Santa María?

  1. Choose your travel dates: What you want to do in Santa Marían and your preferred season can help you decide when to get away.
  2. Work out your budget: Ensure you have enough money to cover everything from transportation and food to activities and flights. Your hotel will probably be the largest expense during your trip to Santa María.
  3. Determine how many days away: Start by listing all the activities and attractions you'd like to get to in Santa María. Then, estimate how long you'll need for each, as well as any travel time.
  4. Bundle your flights and hotel: Awesome destination, check. Length of stay, check. All that's left is to find a Santa María vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.