Title: Book The Best Hotels in Santa María for 2026 from CA $40 - Fully Refundable Options - Expedia.ca

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## Check prices for these dates

Tonight

[Mar 6 - Mar 7](https://www.expedia.ca/Hotel-Search?regionId=553248634664650762&startDate=2026-03-06&endDate=2026-03-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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[Mar 7 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=553248634664650762&startDate=2026-03-07&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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[Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=553248634664650762&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=553248634664650762&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Top Santa María Hotel Reviews

## More cheap stays in Santa María

![Hosteria Casa Blanca Iguazu](https://images.trvl-media.com/lodging/16000000/15370000/15361700/15361606/2a938436_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hosteria Casa Blanca Iguazu

Av. Guaraní 121 Puerto Iguazú Misiones

CA $37

CA $40 total

Mar 8 - Mar 9

[](https://expedia.ca/Puerto-Iguazu-Hotels-Hosteria-Casa-Blanca-Iguazu.h15361606.Hotel-Information)

![Don Raul](https://images.trvl-media.com/lodging/125000000/124510000/124504100/124504070/161d1f33_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Don Raul

Paraguay 417 Puerto Iguazú Misiones

CA $52

CA $55 total

Mar 25 - Mar 26

10/10 Exceptional! (1 review)

[](https://expedia.ca/Puerto-Iguazu-Hotels-Don-Raul.h124504070.Hotel-Information)

![Posada los Tajibos](https://images.trvl-media.com/lodging/20000000/19250000/19249400/19249345/8bdcc929_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Posada los Tajibos

Fray Mamerto Esquiu 48 Puerto Iguazú Misiones

CA $82

CA $85 total

Mar 13 - Mar 14

8.2/10 Very Good! (154 reviews)

[](https://expedia.ca/Puerto-Iguazu-Hotels-Posada-Los-Tajibos.h19249345.Hotel-Information)

![Posada 21 Oranges](https://images.trvl-media.com/lodging/11000000/10630000/10626400/10626379/663486d0_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Posada 21 Oranges

Calle Montecarlo y Av. los inmigrantes Puerto Iguazú Misiones

CA $91

CA $94 total

Mar 16 - Mar 17

9.6/10 Exceptional! (83 reviews)

[](https://expedia.ca/Puerto-Iguazu-Hotels-Posada-21-Oranges.h10626379.Hotel-Information)

![ Z Hotel Boutique](https://images.trvl-media.com/lodging/32000000/31750000/31741300/31741235/86b6191f_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

###  Z Hotel Boutique

Ombu 349 Puerto Iguazú 

CA $96

CA $99 total

Mar 8 - Mar 9

8.8/10 Excellent! (57 reviews)

[](https://expedia.ca/Puerto-Iguazu-Hotels-Z-Apart-Iguazu.h31741235.Hotel-Information)

![Hotel Lilian](https://images.trvl-media.com/lodging/18000000/17340000/17335100/17335004/fa1096c8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Lilian

Fray Luis Beltrán 183 Puerto Iguazú Misiones

[Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F03%2F2026&endDate=21%2F03%2F2026&selected=17335004&PinnedHotelID=17335004&HadPinnedHotel=true&regionId=553248634664650762)

[](https://expedia.ca/Puerto-Iguazu-Hotels-Hotel-Lilian.h17335004.Hotel-Information)

## Frequently asked questions

### What is the best area to stay in Santa María?

> This central area is the heart of Santa María, offering easy access to the town's main facilities and attractions. You'll find most of the local shops, restaurants, and amenities clustered around the square and along the streets branching off it, such as Calle San Martín and Calle Belgrano. The town centre is quite compact and easy to navigate on foot.
> 
>   
> For couples looking for a relaxed and convenient base, staying near Plaza San Martín is ideal. You'll be within a short walk of the historic church, local museums, and the craft market, allowing for pleasant strolls and easy access to evening meals.
> 
>   
> For families, the town centre also offers practical advantages. Being close to the main square means children can enjoy the open space, and you're never far from a cafe for a quick snack or a shop for essentials.

### When is the best time to go to Santa María?

> During these months, you'll experience mild temperatures, typically ranging from 20°C to 28°C, with less humidity than the peak summer months. This makes it ideal for outdoor activities like visiting the nearby Jesuit Missions, exploring the local markets, or simply enjoying the natural surroundings. You'll also find that these periods are less crowded than the summer holidays, allowing for a more relaxed and authentic experience.
> 
>   
> For those who prefer slightly cooler weather and are interested in outdoor adventures without the intense heat, the autumn months of April to June are particularly good. The lush greenery is still prominent, and the air is crisp, great for extended walks or touring the region's historical sites.
> 
>   
> Alternatively, the spring months of September to November offer a wonderful opportunity to see the region come alive with blooming flora. The temperatures are warming up, and the days are generally sunny, providing excellent conditions for sightseeing and enjoying the local culture.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Santa María hotel booking with Expedia?

### How much is the nightly rate at a Santa María hotel?

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