Santa María Vacation Packages

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  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Ready to book your vacation to Santa María?

 

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Santa María Hotel Deals

Gran Melia Iguazú

Gran Melia Iguazú

5 out of 5
Parque Nacional Iguazu Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
The price is CA $935 per night from Nov 7 to Nov 8
CA $935
CA $947 total
Nov 7 - Nov 8
9.4/10 Exceptional! (1,000 reviews)
"Everything was great"

Reviewed on Oct 28, 2026

Gran Melia Iguazú
Hotel Saint George

Hotel Saint George

4 out of 5
Avenida Cordoba 148 Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
The price is CA $188 per night from Nov 3 to Nov 4
CA $188
CA $197 total
Nov 3 - Nov 4
9/10 Wonderful! (1,001 reviews)
"This hotel is located in the central part of Puerto Iguacu. It is close to restaurants, bars and shopping. The rooms are spacious and well maintained. The pool is beautiful. My only negative was with the spa services. I found the massage to be mediocre and rushed. I wouldn't recommend that service. ..."

Reviewed on Oct 27, 2026

Hotel Saint George
Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

5 out of 5
Selva Iriapu Sin Numero Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
The price is CA $523 per night from Dec 1 to Dec 2
CA $523
CA $535 total
Dec 1 - Dec 2
9.2/10 Wonderful! (1,001 reviews)
"The place is nice enough. Unless you are an infant, you'll probably die of old age waiting for your food or drink orders to be filled. Breakfasts are good. The breakfast food quality is acceptable and it's buffet style, so you don't have to wait on the server to bring you the food. If you want a ..."

Reviewed on Oct 30, 2026

Loi Suites Iguazú Hotel
See all 406 properties in Misiones Province
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Santa María vacation package cost?
You can pick up a vacation package to this popular destination on Expedia. But how much your vacation to Santa María costs will depend on the season, length of stay and hotel choice.
What are the cheapest months to go to Santa María?
You can typically find lower prices and greater availability in April, May and June. Browse our cheap Santa María vacation packages and you could get some great off-season deals.
How many days is enough for Santa María?
Generally, a handful of days is enough to explore the major sights during your Santa María vacation. But if you prefer to have more time to rest or go on day tours, think about extending your itinerary.
How to find the best Santa María package deals?
Begin your search for a Santa María package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Santa María package deal right away, simply change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Marían escape underway.
Is it cheaper to book a Santa María vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll usually snag a better deal than booking each component individually. And you'll still get the flexibility to create a customized Santa María vacation by choosing your favourite accommodation type, airline and car class.
When to book a vacation package to Santa María?
If you have your Santa María travel dates locked in, book early to grab some incredible deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for setting off on a whim.
How to plan a trip to Santa María?

  1. Choose your travel dates: What you want to do in Santa Marían and your preferred season can help you decide when to get away.
  2. Work out your budget: Ensure you have enough money to cover everything from transportation and food to activities and flights. Your hotel will probably be the largest expense during your trip to Santa María.
  3. Determine how many days away: Start by listing all the activities and attractions you'd like to get to in Santa María. Then, estimate how long you'll need for each, as well as any travel time.
  4. Bundle your flights and hotel: Awesome destination, check. Length of stay, check. All that's left is to find a Santa María vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.