Mark Twain

St. Louis


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Mark Twain Hotel Deals

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is CA $250 per night from Apr 5 to Apr 6
CA $250
CA $293 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,362 reviews)
The staff at the Drury Inn bu the Arch are second to none! They were friendly, helpful, and efficient. The included meals and pool made traveling with our kids a relaxed and enjoyable time

Reviewed on Apr 1, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is CA $174 per night from Apr 5 to Apr 6
CA $174
CA $203 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,911 reviews)
Would not recommend. Staff was rude. Snack and breakfast areas were disgusting and not refilled throughout the duration. Rooms were gross.

Reviewed on Apr 1, 2026

Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is CA $139 per night from Apr 19 to Apr 20
CA $139
CA $162 total
Apr 19 - Apr 20
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is CA $207 per night from Apr 5 to Apr 6
CA $207
CA $249 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,707 reviews)
Outstanding hotel! Everything about it was great. Easy walks to Enterprise Center, to Busch Stadium and the Arch!

Reviewed on Apr 1, 2026

21C Museum Hotel St Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is CA $235 per night from Apr 12 to Apr 13
CA $235
CA $277 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (3,986 reviews)
The front desk associates were amazing! The valet attendants were amazing! Dinner at Ruth Chris was amazing! We enjoyed our stay!

Reviewed on Apr 1, 2026

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is CA $153 per night from Apr 6 to Apr 7
CA $153
CA $199 total
Apr 6 - Apr 7
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,197 reviews)
room very clean pretty plain for a suite very spacious and comfortable

Reviewed on Apr 1, 2026

Hollywood Casino & Hotel St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Mark Twain

Central West End

Central West End

4/5(6 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.

Midtown

While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.

Midtown
The Grove

The Grove

The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.

The Grove
Downtown West

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

Downtown West
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The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.

The Gate
University City

University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City


Mark Twain

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