The best area to stay in Mount Vernon is near the town centre, particularly around US Highway 280 and US Highway 221.This area is the main commercial hub of Mount Vernon, offering the most convenient access to local amenities and dining options. You'll find most of the town's businesses, including eateries and shops, situated along or just off these main roads. It's a practical and straightforward area for visitors.For travellers passing through or those on a business trip, staying in this central area is ideal. Its proximity to the main highways makes for easy navigation, whether you're arriving, departing, or simply need a place to stop for the night.