Central Missouri Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $1,096 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Central Missouri Vacation

Whether you plan to visit Central Missouri for its rural countryside, spectacular views or something else entirely, this is one destination you'll never forget. Create your ultimate getaway with one of our Central Missouri vacation packages. With so much to see on a trip to Central Missouri, it can be tricky to know where to start. Kick off your journey in Columbia at Mizzou Arena and Columbia Mall — two much-loved attractions here. Another top city worth adding to your itinerary is Osage Beach. Don't miss Bagnell Dam and Lake of the Ozarks and Bagnell Dam Viewpoint. Find some travel buddies and start packing, because your Central Missouri vacation is only a few clicks away with Expedia.

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now

Where to stay in Central Missouri

Find the best Central Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Central Missouri
Default Image

Shawnee Bend

While Shawnee Bend isn't home to many top sights, Sycamore Creek Golf Club and Osage Beach Premium Outlets are some notable places to visit nearby.

Find hotels in Shawnee Bend

Ready to book your vacation to Central Missouri?

 

Choose your dates

Central Missouri Hotel Deals

Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (1,365 reviews)
Lovely king suite with whirlpool.

Reviewed on Mar 3, 2026

Get rates
Stoney Creek Hotel Columbia
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
The price is CA $134 per night from Mar 29 to Mar 30
CA $134
CA $151 total
Mar 29 - Mar 30
includes taxes & fees
9.6/10 Exceptional! (1,389 reviews)
We did not use the pool. Our room was generally clean, although the floor in the bathroom and the corners were not spotless. Staff was polite, friendly, and helpful. The beds were comfortable and breakfast and the evening's food were tasty and adequate for a couple or a family, and most welcome on ...

Reviewed on Mar 3, 2026

Drury Plaza Hotel Columbia East
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
Fully refundableReserve now, pay when you stay
The price is CA $119 per night from Mar 26 to Mar 27
CA $119
CA $134 total
Mar 26 - Mar 27
includes taxes & fees
9/10 Wonderful! (1,752 reviews)
Starting to falter on the edges

Reviewed on Mar 2, 2026

Country Inn & Suites by Radisson, Columbia, MO
See all 4,825 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Central Missouri

Ha Ha Tonka State Park which includes caves and forests as well as a family

Ha Ha Tonka State Park

This state park at the top of a bluff features evocative castle ruins, as well as caves, a natural bridge, sinkholes and a scenic lake.

Ha Ha Tonka State Park
Norwood Hall 320 W 12 Street Rolla Missouri Photo taken on November 2, 2021 One of the first building constructed on the campus of University of Missouri Science and Technology campus.

Missouri University of Science and Technology

Take a campus tour or just explore the area of Missouri University of Science and Technology, during your trip to Rolla. Stroll along this family-friendly area's lakeside, or simply enjoy its coffeehouses.

Missouri University of Science and Technology

Fort Leonard Wood

After visiting Fort Leonard Wood, make a plan to see the other sights and activities in St. Robert. While in this family-friendly area, you can savor the top-notch restaurants.

Fort Leonard Wood

What to do in Central Missouri

Copperhead Mountain Coaster

Copperhead Mountain Coaster - Branson’s Best Mountain Coaster

CA $25
per adult
100% of travellers recommend
Copperhead Mountain Coaster - Branson’s Best Mountain Coaster
2023 Lineup

Legends in Concert Branson Missouri

CA $73
per adult
90% of travellers recommend
Legends in Concert Branson Missouri
Amazing Acrobats: Grand Shanghai Circus Show in Branson

Amazing Acrobats: Grand Shanghai Circus Show in Branson

CA $66
per adult
92% of travellers recommend
Amazing Acrobats: Grand Shanghai Circus Show in Branson
See all activities in Central Missouri

Frequently asked questions

Can I cancel my flight booking to Central Missouri due to COVID-19?
Our handy Customer Service Portal has useful information about canceling or changing your flight due to COVID-19. Before booking, it's wise to check the terms and conditions of your airfare too.
What's the best way to find cheap flights to Central Missouri that have flexible change policies?
It's as easy as can be with Expedia. Firstly, enter your preferred travel dates and click "Search." Next, check the "No change fee" box directly under the "Flexible change policies" heading to the left of your screen. Step 3. Book your cheap and flexible airfare to Central Missouri.
What are some of the general tips for travelers to Central Missouri during the COVID-19 outbreak?
The COVID-19 outbreak may have changed how we travel, but it hasn't stopped our desire to explore. Here are some tips on how to navigate travel's new challenges:
  • Before locking in your flight, see if any travel bans or restrictions apply — in both your origin and destination. Keep informed with the latest updates by checking government and airport websites.
  • You're required to wear a face mask at the airport, including at screening checkpoints. Be prepared to lower your mask for ID purposes when asked by a TSA employee.
  • To reduce the likelihood of cross-contamination, place your boarding pass on the reader yourself and then hold it up for inspection. Do not hand your pass directly to a TSA officer.
  • One liquid hand sanitizer container is now allowed in your carry-on luggage. It must be no bigger than 12 oz (350 ml), and you'll have to remove it from your bag for screening.
  • To minimize handling during the screening process, place personal items such as your phone, wallet and keys into your carry-on instead of the bins.
  • If you're planning to take food on the plane, put it in a clear plastic bag and then into a screening bin. This reduces the likelihood that a TSA employee will need to handle your carry-on bag or food container for inspection.

Which airlines fly to Central Missouri?
United Airlines operates flights into or near Central Missouri, including 52 that touch down at Cape Girardeau Municipal Airport (CGI) each month. Work out your travel dates and then secure your ticket early to score the best deal.
How can I find cheap tickets to Central Missouri?
To get your hands on a great deal to Central Missouri, book well ahead. Also consider using Expedia's handy "flexible dates" feature at the top of your search results. This will list prices for the days around your travel dates. In the last seven days, was the best price for a flight to Central Missouri.
How much is a flight to Central Missouri?
If you were jetting one way from (), you could've locked in a low-cost fare for in the last seven days. Return flights to Central Missouri ranged from to over the same period.
What are the most popular airports to fly into in Central Missouri?
Get ready to pack your suitcase and jet into Cape Girardeau Municipal Airport (CGI), Central Missouri's leading flight hub. Book a fare on one of the 52 flights that touch down at this top destination every month.
When is the cheapest time to fly to Central Missouri?
If you'd prefer to spend your vacation money exploring the delights of Central Missouri rather than on getting there, take off early in the week. The most affordable day to fly is usually Tuesday, with Monday coming in second. With many folks traveling on the weekend, Saturday typically has the highest ticket prices.
How much is a plane ticket to Central Missouri?
In the last seven days, airfares to Central Missouri varied between and . Prices usually rise as your travel date nears, so secure a terrific deal today.
Which airlines with flights to Central Missouri employ COVID-19 cleanliness policies?
Travel by plane now and you'll probably see that things have changed. For instance, most reputable carriers have implemented social distancing and improved hygiene standards. A couple of good examples are:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.