Title: Hotels by Independent in South Carolina Midlands from CA $86 | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/183000/183997-State-House.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Independent in South Carolina Midlands from CA $86 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 21 - Sep 22](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-09-21&endDate=2025-09-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 22 - Sep 23](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-09-22&endDate=2025-09-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Carolina Midlands Independent Hotels ## Our top choices for South Carolina Midlands Independent ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/8f02222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/f75cb7bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/60008f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Crossroads Lake City 9.4/10 Exceptional (777) "Fantastic restaurant on site, clean rooms and friendly staff. Very nice hotel." CA $160 CA $180 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Fitness facility](https://images.trvl-media.com/lodging/23000000/22220000/22214300/22214254/d9ec3f2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/23000000/22220000/22214300/22214254/ec6dc1ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/23000000/22220000/22214300/22214254/63a2bab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Darling Suite](https://images.trvl-media.com/lodging/23000000/22220000/22214300/22214254/84e046fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Trundle Downtown Columbia 9.8/10 Exceptional (949) "Such a cute hotel, I really enjoyed my stay." CA $238 CA $273 total includes taxes & fees Sep 22 - Sep 23 [](https://www.expedia.ca/Columbia-Hotels-Hotel-Trundle.h22214254.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/b733a543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/e9758649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/917b8b10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/cfa3fc89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Columbia-Irmo Harbison Irmo 8.6/10 Excellent (308) "This property was a great stay with our fur babies. I love the spacious room and of course being a pet friendly property. " CA $160 CA $174 total includes taxes & fees Sep 22 - Sep 23 [](https://www.expedia.ca/Irmo-Hotels-StayAPT-Suites-Columbia-Irmo-Harbison.h71943321.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/11000000/10940000/10931100/10931075/fed76e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/11000000/10940000/10931100/10931075/4f102d5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/11000000/10940000/10931100/10931075/df26a103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10940000/10931100/10931075/7dcea9ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carriage House Inn Aiken 9.4/10 Exceptional (446) "The beautiful property was in a great location within walking distance to great shops and restaurants." CA $274 CA $307 total includes taxes & fees Sep 23 - Sep 24 [](https://www.expedia.ca/Aiken-Hotels-Carriage-House-Inn.h10931075.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/39339da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Queen Suite | Private kitchen](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/83bdb053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/acb68e54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Regal mid-King Suite | Private kitchen](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/ff7460f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mantissa Hotel Hartsville 9.2/10 Wonderful (260) "Excellent stay" CA $217 CA $244 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Florence-Hotels-The-Mantissa-Hotel.h15719033.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/900000/893900/893817/6791971c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 King Bed (No Pets Allowed)](https://images.trvl-media.com/lodging/1000000/900000/893900/893817/c1013b0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/900000/893900/893817/91ea3903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/900000/893900/893817/c7965fbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Landmark Inn Hartsville 7.0/10 Good (309) "Great staff" CA $110 CA $128 total includes taxes & fees Sep 22 - Sep 23 [](https://www.expedia.ca/Florence-Hotels-The-Landmark-Inn.h893817.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/119000000/118280000/118271000/118270906/fa9ca9dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 1 Double Bed, Non Smoking, City View](https://images.trvl-media.com/lodging/119000000/118280000/118271000/118270906/804da3ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/119000000/118280000/118271000/118270906/bba65765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/119000000/118280000/118271000/118270906/200d9d49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Broad St Inn Sumter 6.0/10 (6) "I like the price, and the staff. I never experienced bugs or dirty room at all. It was literally a crash spot for me while I was working. For the price and clean room and staff, you get a bang for your buck. " CA $113 CA $127 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Sumter-Hotels-Broad-St-Inn.h118270906.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/102000000/101070000/101069700/101069646/8025f028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101070000/101069700/101069646/bf872483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room, Non Smoking](https://images.trvl-media.com/lodging/102000000/101070000/101069700/101069646/535333df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/102000000/101070000/101069700/101069646/867ff45e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Regency Inn Rock Hill 7.4/10 Good (113) "it is located in a convenient area for shopping, transportation, and quiet " CA $77 CA $86 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Rock-Hill-Hotels-Royal-Regency-Inn.h101069646.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/7895bf64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/cdf5b3db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/bf118dbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite | Private kitchen](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/bca415cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Affordable Suites Florence Florence 9.2/10 Wonderful (110) "Parking was good and quiet spot" CA $87 CA $98 total includes taxes & fees Sep 22 - Sep 23 [](https://www.expedia.ca/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/6000000/5860000/5856000/5855904/bc8bacf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/6000000/5860000/5856000/5855904/43f55277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/6000000/5860000/5856000/5855904/70516945.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5860000/5856000/5855904/99ae65de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Houndslake Houndslake 9.2/10 Wonderful (276) "Amazing place for a relaxing vacation." CA $205 CA $230 total includes taxes & fees Sep 22 - Sep 23 [](https://www.expedia.ca/Aiken-Hotels-The-Inn-At-Houndslake.h5855904.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-05&endDate=2025-10-06®ionId=6057938&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Hotels-Independent.0-0-d6057938--bIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Hotels-Independent.0-0-d6057938--bIndependent.Travel-Guide-Filter-Hotels) ## Top South Carolina Midlands Hotel Reviews ![Super 8 by Wyndham Harbison/Parkridge Hospital](//images.trvl-media.com/lodging/1000000/530000/523100/523046/42de4f92_y.jpg) ### Super 8 by Wyndham Harbison/Parkridge Hospital 10/10 Excellent "The staff was very friendly. Had a great week with my family." [](https://expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-HarbisonParkridge-Hospital.h523046.Hotel-Information) ![Hilton Garden Inn Columbia/Harbison](//images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "Everyone was so nice and helpful" [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![La Quinta Inn by Wyndham Columbia SE / Fort Jackson](//images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e_y.jpg) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson 10/10 Excellent "Staff was very friendly and helpful" [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![Baymont by Wyndham Columbia Fort Jackson](//images.trvl-media.com/lodging/1000000/580000/574500/574461/c68af965_y.jpg) ### Baymont by Wyndham Columbia Fort Jackson 10/10 Excellent "Great location great staff just a great place " [](https://expedia.ca/Columbia-Hotels-Baymont-By-Wyndham-Columbia-Fort-Jackson.h574461.Hotel-Information) ![Sleep Inn Near Ft Jackson](//images.trvl-media.com/lodging/1000000/130000/120500/120428/f4f5ae62_y.jpg) ### Sleep Inn Near Ft Jackson 10/10 Excellent "The service was very friendly and professional. I didn’t get a early check in, but other than, I enjoyed my stay and service." [](https://expedia.ca/Columbia-Hotels-Sleep-Inn-Near-Ft-Jackson.h120428.Hotel-Information) ![Marriott Columbia](//images.trvl-media.com/lodging/1000000/20000/17400/17353/4bcf0c43_y.jpg) ### Marriott Columbia 10/10 Excellent "Convenient located downtown with very nice rooms." [](https://expedia.ca/Columbia-Hotels-Marriott-Columbia.h17353.Hotel-Information) ![ La Quinta Inn by Wyndham Columbia NE/Fort Jackson](//images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50_y.jpg) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson 10/10 Excellent "Very clean and great breakfast " [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Clarion Pointe Near University](//images.trvl-media.com/lodging/1000000/30000/22100/22006/69d65d2e_y.jpg) ### Clarion Pointe Near University 10/10 Excellent "Nice room. Good area. Comfortable stay for a road trip. " [](https://expedia.ca/Rock-Hill-Hotels-Clarion-Pointe-Rock-Hill-Near-Training-Camp.h22006.Hotel-Information) ![Tru By Hilton Columbia Downtown](//images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3840h2557x0y3-1e9d91e1_y.jpg) ### Tru By Hilton Columbia Downtown 10/10 Excellent "The hotel is immaculate! Everything is so clean and new. The breakfast in the morning was delicious!!! Definitely NOT your typical free breakfast! Had many hot items including a breakfast taco bar that amazing!" 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