Barrio de Santiago

Mérida

A historic stone gate with intricate carvings and two towers.
A gallery with six framed artworks on the walls and a chandelier hanging from the ceiling.
A street scene with a colorful cart, parked cars, and buildings.
A street with a restaurant, outdoor seating, and parked cars.
A staircase with ornate railings, a star-shaped light fixture, and a chessboard in the background.

Stay near popular Barrio de Santiago attractions

Casa Frederick Catherwood

9.0/10 (4 reviews)
<p>Casa Frederick Catherwood offers a vibrant cultural atmosphere, showcasing stunning galleries that celebrate art and history, making it a must-visit for any traveller in the area.</p>
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Things to do

Isla Columpios & Progreso Day Trip

Isla Columpios, Corchito & Progreso Day Tour

CA $112
per adult
94% of travellers recommend
Isla Columpios, Corchito & Progreso Day Tour
Mérida: Panoramic Sightseeing Tour Bus Ticket with 2 Routes

Mérida México: Panoramic Sightseeing City Tour with 2 Routes

CA $13
per adult
84% of travellers recommend
Mérida México: Panoramic Sightseeing City Tour with 2 Routes
The red ones

Las Coloradas, Río Lagartos and Playa Cancunito Tour from Mérida

CA $153
per adult
90% of travellers recommend
Las Coloradas, Río Lagartos and Playa Cancunito Tour from Mérida
Cenote Yuum Kimil

4 Cenotes Tour in Homún all inclusive from Merida

CA $110
per adult
94% of travellers recommend
4 Cenotes Tour in Homún all inclusive from Merida
Kabah

Tour to Uxmal Kabah and Chocolate Museum from Mérida

CA $105
per adult
100% of travellers recommend
Tour to Uxmal Kabah and Chocolate Museum from Mérida
Chichen Pueblos Magicos, Izamal + Valladolid Day Trip

Chichen Itza, Izamal & Noolha Cenote Day Trip - Traditional Lunch Included

CA $168
per adult
92% of travellers recommend
Chichen Itza, Izamal & Noolha Cenote Day Trip - Traditional Lunch Included
See all activities in Mérida

Barrio de Santiago Hotel Deals

Hotel Casa 57

Hotel Casa 57

3 out of 5
539 C. 57 Centro Mérida Yuc.
The price is CA $55 per night from Nov 2 to Nov 3
CA $55
CA $66 total
Nov 2 - Nov 3
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hotel Casa 57
Hotel Ambassador Merida

Hotel Ambassador Merida

3 out of 5
Calle 59 No.546 X 68 Mérida YUC
The price is CA $44 per night from Nov 3 to Nov 4
CA $44
CA $54 total
Nov 3 - Nov 4
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (1,000 reviews)
"Por el precio esta bien, el precio es razonable por las instalaciones. Ss viejo y la regadera se ve muy vieja y ocupa renovación al igual que todo el hotel elevador, pasillos etc. pero igual esta bien ubicado y a buen precio"

Reviewed on Oct 24, 2026

Hotel Ambassador Merida
Casa Loreto 1893

Casa Loreto 1893

5 out of 5
619 Calle 59 Mérida
The price is CA $245 per night from Nov 29 to Nov 30
CA $245
CA $295 total
Nov 29 - Nov 30
includes taxes & fees
Book a stay at this luxury hotel in Mérida. Enjoy free WiFi, free parking, and room service. Popular attractions Plaza Grande and Paseo de Montejo are located ...
9.8/10 Exceptional! (178 reviews)
"Amazing place, super recommended, amenities and people are amazing, and the food really good, I’m coming back with the rest of the family"

Reviewed on Oct 26, 2026

Casa Loreto 1893
Casa Aura Hotel, Mérida

Casa Aura Hotel, Mérida

3.5 out of 5
Calle 57, 543-A, entre 66 y 68 Mérida YUC
The price is CA $61 per night from Nov 29 to Nov 30
CA $61
CA $73 total
Nov 29 - Nov 30
includes taxes & fees
Book a stay at this boutique hotel in Mérida. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ...
Casa Aura Hotel, Mérida
Hotel Unknown

Hotel Unknown

3.5 out of 5
559 Calle 53 Mérida YUC
The price is CA $119 per night from Nov 27 to Nov 28
CA $119
CA $143 total
Nov 27 - Nov 28
includes taxes & fees
Book a stay at this spa hotel in Mérida. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (473 reviews)
"Staff is wonderful."

Reviewed on Oct 26, 2026

Hotel Unknown
Casona 61 Boutique Hotel

Casona 61 Boutique Hotel

3.5 out of 5
Calle 61 entre 66 y 68 Mérida YUC
The price is CA $72 per night from Nov 10 to Nov 11
CA $72
CA $87 total
Nov 10 - Nov 11
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (433 reviews)
"This was a perfect stay. The staff were very helpful and available at all hours of the day. The property was very clean and the room was spacious and comfortable. I did not get to take advantage of the breakfast, but I know it was available every day. I would stay again! I highly recommend."

Reviewed on Oct 29, 2026

Casona 61 Boutique Hotel
See all 1,383 properties in Barrio de Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Barrio de Santiago

Find the best Barrio de Santiago areas and neighborhoods for the activities you enjoy most. Learn more about Barrio de Santiago
Learn more about Barrio de Santiago
A historic building with a clock tower, a street with light trails from moving vehicles, and a red building with a sign.

Mérida Centro

Mérida Centro is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Plaza Grande or Paseo 60.
A historic building with ornate architecture, palm trees, and well-maintained landscaping.
Photo by Tony Lozano
Open Photo by Tony Lozano

Zona Paseo Montejo

While visiting Zona Paseo Montejo, you might make a stop by sights like Paseo 60 and Paseo de Montejo.
A long pier extending into the ocean with clear turquoise water and a clear blue sky.

Chelem

You might make a stop by Chelem Park while you're exploring Chelem.
A row of boats on a beach with a sunset in the background.
Photo by Alex Vizcaino
Open Photo by Alex Vizcaino

Chicxulub Puerto

Travelers like the beaches in Chicxulub Puerto, and Playa Uaymitun is a top attraction you might want to visit.
A meal with tacos, a salad, and a drink at a restaurant.
Photo by Alba and John
Open Photo by Alba and John

Santa Lucia

While there might not be top attractions in Santa Lucia, you can explore the larger area and discover places like Plaza Grande and Paseo 60.

Barrio de Santiago

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