Mayo Clinic Vacation Packages

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Top Holiday Package Deals in Mayo Clinic

Price found within the past 48 hours. Click for updated prices.
Westgate Painted Mountain Golf Resort

Westgate Painted Mountain Golf Resort

4 out of 5
East Mesa
Price was CA $1,342, price is now CA $635 per person
CA $635
per person
Oct 16 - Oct 20
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to Phoenix (PHX)
8.4/10 Very Good! (1,002 reviews)
Beautiful pool area. Very respectful staff. My only complaint would be the floors in the room looked clean, but they turned your feet black.

Reviewed on Aug. 30, 2025

Mountain Shadows Resort Scottsdale

Mountain Shadows Resort Scottsdale

4.5 out of 5
Price was CA $2,225, price is now CA $1,219 per person
CA $1,219
per person
Oct 2 - Oct 6
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Phoenix (PHX)
9.6/10 Exceptional! (1,015 reviews)
I loved the rooms very modern. The resort gave upscale luxury the amenities and customer service was exceptional

Reviewed on Sep. 1, 2025

Arizona Biltmore, LXR Hotels & Resorts

Arizona Biltmore, LXR Hotels & Resorts

5 out of 5
Camelback East
Price was CA $2,272, price is now CA $1,407 per person
CA $1,407
per person
Nov 23 - Nov 29
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to Phoenix (PHX)
9/10 Wonderful! (1,005 reviews)
This is a beautiful hotel,with top notch service and very friendly staff.We had a great time and we'll definitely be back

Reviewed on Aug. 31, 2025

Lantern Light Inn - Romantic Getaway

Lantern Light Inn - Romantic Getaway

3.5 out of 5
West Sedona
Price was CA $2,394, price is now CA $1,491 per person
CA $1,491
per person
Nov 15 - Nov 22
found 1 day ago
Roundtrip flight included
Vancouver (YVR) to Phoenix (PHX)
9.4/10 Exceptional! (1,000 reviews)
I love the antique furniture in the units and the very private court yards. The units are very quiet! It is for adults, no children or pets. Staff is very helpful and friendly. This is my 2 nd time staying here. Love it!

Reviewed on Aug. 14, 2025

Hotel Valley Ho

Hotel Valley Ho

4.5 out of 5
Old Town
Price was CA $2,021, price is now CA $1,263 per person
CA $1,263
per person
Nov 6 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Phoenix (PHX)
9.6/10 Exceptional! (1,898 reviews)
Tower suite is perfect!

Reviewed on Sep. 1, 2025

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most. Learn more about Mayo Clinic
Downtown Phoenix showing signage and night scenes

Downtown Phoenix

3 out of top 10 points of interest in this area
3.5/5(148 area reviews)

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

Find hotels in Downtown Phoenix
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Mayo Clinic vacation package cost?
Starting from as low as CA $635, a package is your gateway to low-priced travel. Customize your Mayo Clinic trip by choosing from our extensive range of hotels, flights and rental cars.
How do I get a cheap travel package to Mayo Clinic?
Our Mayo Clinic vacation packages promise plenty of savings for the savvy globetrotter. For the best deals, simply combine your flights, hotels and activities into an affordable package. But low prices are just the beginning of your next unforgettable adventure. Book with Expedia and and you'll have over 550 airlines and 1,000,000 properties throughout the world to pick from. No matter your budget or style, there's a vacation package that's perfect for you.
Where should I stay in Mayo Clinic?
Cross Tournament Players Club of Scottsdale off your must-see list and then stay right near it. Soak up the exciting vibe around this terrific attraction and drop by whenever the mood strikes!
What are the top hotels in Mayo Clinic?
Whether you plan to stay for a night or a week in Mayo Clinic, you'll get a great night's rest at Sonesta Select Scottsdale at Mayo Clinic Campus. This option is popular with plenty of travelers.
How far in advance should I book my Mayo Clinic vacation?
Search Expedia to compare international flights as early as possible. In most cases, you can purchase a seat up to 12 months prior to departure. If it's too early for your preferred carrier, or you have to book last minute, don't despair. Cheap fares to Mayo Clinic sometimes occur within weeks of departure.
What does an Expedia Mayo Clinic travel package include?
It all depends on what sort of trip you have in the works. Mayo Clinic vacation deals can include car rentals, hotels and flights. You can mix and match to find the travel package that suits your style and budget. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Mayo Clinic travel package?
When you book your flights, hotels and car rentals together, you'll walk away with awesome discounts. Whether you're planning a beach break in a villa or want to stay in a fancy hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Mayo Clinic Expedia vacation package?
You can, and with over 550 airlines to choose from all over the world, you've got lots of choice. Take a look at the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mayo Clinic vacation package?
You sure can, and we'll help you every step of the way. You may be able to cancel and rebook your Mayo Clinic vacation package at no cost if you booked in the last 24 hours. But you may incur a fee from your hotel, airline or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, have a look at our Customer Service Portal for further information.

Discover the most popular places to visit in Mayo Clinic

Arizona State University

Arizona State University

Explore the campus of Arizona State University, a top college in Tempe. Amble around the area's lakeside or seek out the jogging trails.

Arizona State University
Phoenix Convention Center

Phoenix Convention Center

During your trip, find out what's happening at Phoenix Convention Center, a top convention center in Phoenix. Experience the acclaimed theater scene and fascinating museums in this vibrant area.

Phoenix Convention Center
Grand Canyon University

Grand Canyon University

Enjoy the collegiate vibe with a visit to Grand Canyon University, a well-known college in Phoenix. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Grand Canyon University

Things to do

Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert

Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert

CA $141
per traveller
100% of travellers recommend
Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert
Phoenix Zoo Admission Ticket

Phoenix Zoo Admission Ticket

CA $55
per adult
86% of travellers recommend
Phoenix Zoo Admission Ticket
Scottsdale: Museum of Illusions Ticket at Arizona Boardwalk

Scottsdale: Museum of Illusions Ticket at Arizona Boardwalk

CA $35
per adult
Scottsdale: Museum of Illusions Ticket at Arizona Boardwalk
See all activities in Phoenix
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.