Title: Book The Best Hotels in Lyon, MS for 2026 from CA $107 - Fully Refundable Options - Expedia.ca

[Hotels in Lyon](https://expedia.ca/Lyon-Hotels.d553248634998705303.Travel-Guide-Hotels)[Vacation Rentals in Lyon](https://expedia.ca/Lyon-Vacation-Rentals.d553248634998705303.Travel-Guide-VacationRentals)[Lyon Car Rentals](https://expedia.ca/Car-Rentals-In-Lyon.d553248634998705303.Car-Rental-Guide)

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## Go beyond your typical stay in Lyon

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Lyon%2C+Mississippi%2C+United+States+of+America&regionId=553248634998705303&latLong=34.217887%2C-90.542043&adults=2&startDate=2026-03-03&d1=2026-03-03&endDate=2026-03-05&d2=2026-03-05&amenities=PETS)

## Check prices for these dates

Tonight

[Feb 17 - Feb 18](https://www.expedia.ca/Hotel-Search?regionId=553248634998705303&startDate=2026-02-17&endDate=2026-02-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel)

Tomorrow

[Feb 18 - Feb 19](https://www.expedia.ca/Hotel-Search?regionId=553248634998705303&startDate=2026-02-18&endDate=2026-02-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel)

This weekend

[Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=553248634998705303&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel)

Next weekend

[Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=553248634998705303&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel)

## Our top choices for Lyon hotels

![Exterior](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/d859aa54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![First Floor East](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/3bdb990c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/f4c15177.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/7467caab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travelers Hotel

[](https://www.expedia.ca/Clarksdale-Hotels-Travelers-Hotel.h34868083.Hotel-Information)

Clarksdale

9.8/10

Exceptional

(279 reviews)

"Great location, clean and simple accomodation."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barry

CA $207

CA $226 total

includes taxes & fees

Feb 21 - Feb 22

[](https://www.expedia.ca/Clarksdale-Hotels-Travelers-Hotel.h34868083.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/ee0738d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/55faa465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/e34ceb08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/20bde9f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Clarksdale

[](https://www.expedia.ca/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information)

Clarksdale

8.2/10

Very good

(350 reviews)

"Staff was great and very hospitable, but the bathroom wasn't very clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ROBERT

CA $185

CA $201 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/766fdf07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/41578708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/d6d31cff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/94b5934f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Clarksdale

[](https://www.expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information)

Clarksdale

7.4/10

Good

(718 reviews)

"The rooms could be a little more clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Courtney

CA $121

CA $131 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/c0e992b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Smoking](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/2606ec8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/e3029007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Smoking](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/4b0df372.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Americas Best Value Inn & Suites Clarksdale

[](https://www.expedia.ca/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information)

Clarksdale

5.8/10

(410 reviews)

"Good location in town"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samuel

CA $98

CA $107 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/e0dd2ca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/3e64df31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/82cb9926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/569f0e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Auberge Clarksdale Blues Hostel

[](https://www.expedia.ca/Clarksdale-Hotels-Auberge-Clarksdale-Blues-Hostel.h38924451.Hotel-Information)

Clarksdale

9.6/10

Exceptional

(93 reviews)

"Great hosts, restrooms, and location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karl

[](https://www.expedia.ca/Clarksdale-Hotels-Auberge-Clarksdale-Blues-Hostel.h38924451.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-03&endDate=2026-03-04&regionId=553248634998705303&adults=2&sort=RECOMMENDED&openPlayBack=true)

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## Top Lyon Hotel Reviews

## Recent Reviews in Lyon

![Casa D’Amore!!!!  Adorable home less than 1/2 mile from downtown Clarksdale](https://images.trvl-media.com/lodging/114000000/113250000/113243700/113243634/467c648a_y.jpg)

### Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale

10/10 Excellent

" Very easy check in. Rooms clean and comfortable with all néeded amenities. Located near downtown and accessible to shopping. Will stay here again if in the area. "

[](https://expedia.ca/Clarksdale-Hotels-Casa-DAmore-Adorable-Home-Less-Than-12-Mile-From-Downtown-Clarksdale.h113243634.Hotel-Information)

![Hampton Inn Clarksdale](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/e34ceb08_y.jpg)

### Hampton Inn Clarksdale

10/10 Excellent

"Our room was very nice and the young lady at the desk was informative and friendly. I would definitely stay here again if I find myself back in Clarksdale. "

[](https://expedia.ca/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information)

![Auberge Clarksdale Blues Hostel](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/82cb9926_y.jpg)

### Auberge Clarksdale Blues Hostel

10/10 Excellent

"We stayed here for a few days in January, and there were few guests at the time. We loved it! It was beautiful, clean, and well-run. "

[](https://expedia.ca/Clarksdale-Hotels-Auberge-Clarksdale-Blues-Hostel.h38924451.Hotel-Information)

![Quality Inn](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/766fdf07_y.jpg)

### Quality Inn

10/10 Excellent

"Evwrything was extremely excellent!!"

[](https://expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information)

![Travelers Hotel](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/cc59a6f5_y.jpg)

### Travelers Hotel

10/10 Excellent

"Very nice, "

[](https://expedia.ca/Clarksdale-Hotels-Travelers-Hotel.h34868083.Hotel-Information)

![Cottage on riverbank one mile from Clarksdale in gated community](https://images.trvl-media.com/lodging/79000000/79000000/78996000/78995934/9f913091_y.jpg)

### Cottage on riverbank one mile from Clarksdale in gated community

10/10 Excellent

"The property was wonderful. The beds are absolutely the most comfortable ever, as was the sofa. Very quiet and peaceful. Just what we were looking for."

[](https://expedia.ca/Clarksdale-Hotels-Cottage-On-The-Sunflower-River.h78995934.Hotel-Information)

![Sunset Log Cabin](https://images.trvl-media.com/lodging/97000000/96760000/96758600/96758575/07f49a54_y.jpg)

### Sunset Log Cabin

10/10 Excellent

"A true cabin experience but feels comfortable like home. It is close to the road but I was able to tune out the car noises. The view of sunset is amazing even in the winter time with the already harvested cotton field. All the necessary accessories are provided and very close to town. I’d suggest staying here. "

[](https://expedia.ca/Clarksdale-Hotels-Sunset-Log-Cabin.h96758575.Hotel-Information)

![Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS](https://images.trvl-media.com/lodging/102000000/101150000/101144900/101144826/12bbff96_y.jpg)

### Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS

10/10 Excellent

"On a quiet street with nice homes just a two minute drive or walk to the music center. "

[](https://expedia.ca/Clarksdale-Hotels-Get-To-BLUES-In-At-Rustys-Roost.h101144826.Hotel-Information)

![Americas Best Value Inn & Suites Clarksdale](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/c0e992b8_y.jpg)

### Americas Best Value Inn & Suites Clarksdale

10/10 Excellent

"Yes"

[](https://expedia.ca/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information)

## More cheap stays in Lyon

![Americas Best Value Inn & Suites Clarksdale](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/c0e992b8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Americas Best Value Inn & Suites Clarksdale

350 South State Street Clarksdale MS

CA $98

CA $107 total

Feb 22 - Feb 23

includes taxes & fees

5.8/10 (410 reviews)

[](https://expedia.ca/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information)

![Quality Inn](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/766fdf07_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Quality Inn

818 South State Street Clarksdale MS

CA $121

CA $131 total

Mar 1 - Mar 2

includes taxes & fees

7.4/10 Good! (718 reviews)

[](https://expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information)

![Hampton Inn Clarksdale](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/e34ceb08_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS

CA $185

CA $201 total

Mar 1 - Mar 2

includes taxes & fees

8.2/10 Very Good! (350 reviews)

[](https://expedia.ca/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information)

![Travelers Hotel](https://images.trvl-media.com/lodging/35000000/34870000/34868100/34868083/cc59a6f5_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Travelers Hotel

212 3rd St Clarksdale MS

CA $207

CA $226 total

Feb 21 - Feb 22

includes taxes & fees

9.8/10 Exceptional! (279 reviews)

[](https://expedia.ca/Clarksdale-Hotels-Travelers-Hotel.h34868083.Hotel-Information)

![Auberge Clarksdale Blues Hostel](https://images.trvl-media.com/lodging/39000000/38930000/38924500/38924451/82cb9926_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Auberge Clarksdale Blues Hostel

164 Delta Ave Clarksdale MS

[Get rates](https://expedia.ca/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=38924451&PinnedHotelID=38924451&HadPinnedHotel=true&regionId=553248634998705303)

9.6/10 Exceptional! (93 reviews)

[](https://expedia.ca/Clarksdale-Hotels-Auberge-Clarksdale-Blues-Hostel.h38924451.Hotel-Information)

![High Cotton Condos](https://images.trvl-media.com/lodging/8000000/7380000/7374500/7374432/7583d1b4_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### High Cotton Condos

249 Delta Ave Clarksdale MS

[Get rates](https://expedia.ca/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=7374432&PinnedHotelID=7374432&HadPinnedHotel=true&regionId=553248634998705303)

8.8/10 Excellent! (6 reviews)

[](https://expedia.ca/Clarksdale-Hotels-High-Cotton-Condos.h7374432.Hotel-Information)

## Hotels in Lyon with star rating

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

3 properties

[](https://expedia.ca/3Star-Lyon-Hotels.s30-0-d553248634998705303.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

6 properties

[](https://expedia.ca/2Star-Lyon-Hotels.s20-0-d553248634998705303.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Lyon?

> This area is the most convenient for visitors as it's where you'll find the limited lodging options and easy access to the main roads. Lyon is a very small town, so the "best" area is essentially the most central and accessible part.
> 
>   
> For solo travellers or couples passing through, staying directly in Lyon offers a practical stop.

### When is the best time to go to Lyon?

> These periods offer pleasant weather, with mild temperatures and less humidity, making it ideal for exploring the area comfortably. You'll find it's a great time for outdoor activities without the intense heat of summer or the cooler temperatures of winter.
> 
>   
> Spring brings blooming flora and a generally uplifting atmosphere, great for those who enjoy strolls and appreciating natural beauty.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Lyon hotel booking with Expedia?

### How much is the nightly rate at a Lyon hotel?

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