Title: Isla Santa María Vacation Rentals from CA $104: Short-Term Rentals for 2026 | Expedia.ca

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![Sea lions soaking in some rays on the island of espanola in the Galapagos. Unfortunately no mai tai's on this beach. #LifeAtExpedia #nature](https://images.trvl-media.com/place/739209696364867584/329f8833-28e7-41c2-a4af-1e9e3462ce94.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Delen Wong

![](https://images.trvl-media.com/place/739209696364867584/329f8833-28e7-41c2-a4af-1e9e3462ce94.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=739209696364867584&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=739209696364867584&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 8 - May 10](https://www.expedia.ca/Hotel-Search?regionId=739209696364867584&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 5 - Jun 7](https://www.expedia.ca/Hotel-Search?regionId=739209696364867584&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Isla Santa María vacation rentals

![Family Duplex, 2 Bedrooms, Private Bathroom, Garden View (Courtyard ) | Terrace/patio](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/ffb9bce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Studio Suite, 1 Bedroom, Non Smoking, Garden View | Private kitchen](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/c6f9521c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/392aa62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Ensuite (One bedroom King)](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/34c553bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Torre Mar Galapagos Boutique Suites

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Boutique-Suites.h16786878.Hotel-Information)

Puerto Ayora

9.2/10

Wonderful

(19 reviews)

"Very nice suite, clean, quiet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Masoud

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Boutique-Suites.h16786878.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/9468ea94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Quadruple Room, 1 Bedroom](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/95d1d08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Quadruple Room, 1 Bedroom | Private kitchen](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/7ebdf614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/e9355473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Suites

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Suites.h34937768.Hotel-Information)

Puerto Ayora

9.4/10

Exceptional

(24 reviews)

"Check was early and friendly staff Room was super clean and comfortable"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy

CA $114

CA $125 total

Feb 17 - Feb 18

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Suites.h34937768.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/a58537c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/d3c64b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/d98281b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/b8157967.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Bedroom Suite ON THE Second High Floor AT Ariana\`s Galapagos Hostal

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Queen-Bedroom-Suite-ON-THE-Second-High-Floor-AT-Arianas-Galapagos-Hostal.h102780548.Hotel-Information)

Puerto Ayora

CA $67

CA $104 total

Feb 17 - Feb 18

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Queen-Bedroom-Suite-ON-THE-Second-High-Floor-AT-Arianas-Galapagos-Hostal.h102780548.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/122000000/121720000/121711200/121711113/a8eb4c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![8 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121720000/121711200/121711113/32a60550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, books](https://images.trvl-media.com/lodging/122000000/121720000/121711200/121711113/e1c371cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/122000000/121720000/121711200/121711113/141f97bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Torre Mar Galapagos Villa

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Villa.h121711113.Hotel-Information)

Puerto Ayora, Santa Cruz Island

10/10

Exceptional

(1 review)

"We had a very nice time staying at Torre Mar. It was very conveniently located. We were 5 families...me (the mom) and my 4 kids, their spouses and 6 grandkids. Everyone had their own "suite". The advertising is a little confusing. I thought we were renting a "home", and then realized it was an apartment/hotel....but as I said, it was very nice for each family to have private space. The owner John was very friendly, although we did have some miscommunication issues, which is interesting...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Betty A.

CA $1,858

CA $2,397 total

Feb 20 - Feb 21

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Villa.h121711113.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/104000000/103430000/103424700/103424658/784c1849.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/104000000/103430000/103424700/103424658/6359bb06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/104000000/103430000/103424700/103424658/bea60ccd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103430000/103424700/103424658/45bbaa21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### KING SIZE BED & TWIN SIZE BED WITH PRIVATE BATHROOM ON SECOND FLOOR

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h103424658.Hotel-Information)

Puerto Ayora

CA $41

CA $74 total

Feb 14 - Feb 15

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h103424658.Hotel-Information)

![6 bedrooms, WiFi](https://images.trvl-media.com/lodging/125000000/124600000/124595200/124595164/9cc38edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![6 bedrooms, WiFi](https://images.trvl-media.com/lodging/125000000/124600000/124595200/124595164/ed6ecff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![6 bedrooms, WiFi](https://images.trvl-media.com/lodging/125000000/124600000/124595200/124595164/38c2bf2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/125000000/124600000/124595200/124595164/e0550d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious 6-bedroom building in superb Puerto Ayora with AC

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Spacious-6-Bedroom-Building-In-Superb-Puerto-Ayora-With-AC.h124595164.Hotel-Information)

Puerto Ayora

CA $44

CA $77 total

Feb 14 - Feb 15

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Spacious-6-Bedroom-Building-In-Superb-Puerto-Ayora-With-AC.h124595164.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/9465b582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/daa6d638.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/5328eb63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, stovetop, coffee/tea maker, blender](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/a87cb59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TWO Bedrooms Apartment ON THE Ground Floor IN Ariana\`s Galapagos Hostal

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h102721840.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(1 review)

"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Dean P.

CA $94

CA $135 total

Feb 16 - Feb 17

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h102721840.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/e9b7ef2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/4776976b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/a5ec6899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/8b0d2620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### GALAPAGOS DIVER ESTUDIO.

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h110134025.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(1 review)

"Perfect start to finish. Very clean! Drinking water provided. The host helped us with a small hiccup regarding our transfer so we were able to catch the ferry to San Cristóbal with no problem. Highly recommend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shannyn Z.

CA $75

CA $122 total

Feb 15 - Feb 16

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h110134025.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/104000000/103200000/103193000/103192998/1cd8189f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/104000000/103200000/103193000/103192998/80e1d3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103200000/103193000/103192998/c544ac54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103200000/103193000/103192998/c24a623e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### KING-SIZE BED OR TWO TWIN BEDS SUITE ON SECOND FLOOR WITH CITY VIEW BALCONY

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h103192998.Hotel-Information)

Puerto Ayora

CA $41

CA $74 total

Feb 14 - Feb 15

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h103192998.Hotel-Information)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f0249e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/5b0760b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f1c0fb19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, coffee/tea maker, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/6f52aa05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Vacacional en Puerto Ayora, Santa Cruz, Galápagos

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(1 review)

"Nice and beautiful house to stay very impressed "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $152

CA $180 total

Mar 1 - Mar 2

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information)

![Luxury Apartment, Balcony | Living area](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/39eae50b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/987560e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment, Balcony | Balcony](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/992ac688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment, Balcony | Living area](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/7209e130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galapagos Coliving Ecuador Casa Tuna

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Galapagos-Coliving-Ecuador-Casa-Tuna.h106882041.Hotel-Information)

Puerto Ayora

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Galapagos-Coliving-Ecuador-Casa-Tuna.h106882041.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/ebf60a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/753f38a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/b574e039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/d7cc9d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Two Bedroom house - The Galapagos Pearl Hotel

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(1 review)

"We stayed 3 nights in the "casa grande" associated with the Galapagos Pearl Hotel and could not have been more pleased. The casa has 2 bedrooms, a small kitchen, one bathroom, and is conveniently located right next to the pool and the outdoor dining area where Yolanda serves breakfast. Your room is cleaned every day. The garden surrounding the pool and casa is lush and full of geckos, cats, and beautiful plantings. Yolanda is from the Galapagos, she is a wonderful host and her daughter helped us...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura E.

CA $272

CA $343 total

Feb 14 - Feb 15

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/910a26ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/e5fb900f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/6cb34f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/59b60aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Jardin de Galápagos. 

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Jardin-De-Galapagos.h100640217.Hotel-Information)

Galápagos Islands

CA $92

CA $164 total

Feb 16 - Feb 17

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Jardin-De-Galapagos.h100640217.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/6e3cf51a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/f20e4de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/247eabf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace, books](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/9f903199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Island Life Two-Bedroom Galapagos Casita

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(3 reviews)

"We had a great time and are grateful to John and Donna for hosting us. The casita was very comfortable and quiet. Great wifi and air conditioning for when we needed to relax. Thank you again!"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Victoria K.

CA $210

CA $269 total

Mar 1 - Mar 2

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/406de75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/baa439a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/6408dac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/7a5abddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TWO Bedrooms Apartment ON THE First Floor IN Ariana\`s Galapagos Hostal

[](https://www.expedia.ca/Puerto-Ayora-Hotels-TWO-Bedrooms-Apartment-ON-THE-First-Floor-IN-Arianas-Galapagos-Hostal.h103058515.Hotel-Information)

Puerto Ayora

CA $94

CA $135 total

Feb 15 - Feb 16

[](https://www.expedia.ca/Puerto-Ayora-Hotels-TWO-Bedrooms-Apartment-ON-THE-First-Floor-IN-Arianas-Galapagos-Hostal.h103058515.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/e27d3e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/41f41cf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/735d660b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/8508134b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ¡Bienvenido a tu hogar isleño en Galápagos! 

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Bienvenido-A-Tu-Hogar-Isleno-En-Galapagos.h100177018.Hotel-Information)

Puerto Ayora

CA $111

CA $138 total

Feb 17 - Feb 18

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Bienvenido-A-Tu-Hogar-Isleno-En-Galapagos.h100177018.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/113000000/112680000/112676500/112676466/a8ae6adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112680000/112676500/112676466/9a885418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/113000000/112680000/112676500/112676466/6bc82d4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112680000/112676500/112676466/e8965b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Cozy-2-Bedroom-Apartment-In-Charming-Puerto-Ayora-With-AC.h112676466.Hotel-Information)

Puerto Ayora

CA $111

CA $138 total

Mar 2 - Mar 3

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Cozy-2-Bedroom-Apartment-In-Charming-Puerto-Ayora-With-AC.h112676466.Hotel-Information)

![2 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/23000000/22870000/22869400/22869358/0d93ae7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/23000000/22870000/22869400/22869358/0f077b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/23000000/22870000/22869400/22869358/63983c7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, books](https://images.trvl-media.com/lodging/23000000/22870000/22869400/22869358/4548d4a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### This two-bedroom is a perfect island getaway.

[](https://www.expedia.ca/Puerto-Ayora-Hotels-This-Two-Bedroom-Is-A-Perfect-Island-Getaway.h22869358.Hotel-Information)

Puerto Ayora, Santa Cruz Island

8.8/10

Excellent

(5 reviews)

"Donna communicated with us before our trip to provide information about arrival and to offer transportation assistance from the airport. Once we were there she offered to arrange tours, suggest dining places and made reservations for us. She did everything she could to make our stay easy and enjoyable. On one of the tours she was our guide. That was so helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cynthia H.

CA $210

CA $271 total

Feb 17 - Feb 18

[](https://www.expedia.ca/Puerto-Ayora-Hotels-This-Two-Bedroom-Is-A-Perfect-Island-Getaway.h22869358.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/937eb7c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/50fe223c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/ff40a829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/89f46e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Island life Duplex great for groups

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Duplex-Great-For-Groups.h121711100.Hotel-Information)

Puerto Ayora, Santa Cruz Island

CA $381

CA $491 total

Feb 22 - Feb 23

[](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Duplex-Great-For-Groups.h121711100.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/aa67740e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/2ebaba6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/77881106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/f2ba9c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### FAMILY SUITE in Puerto Ayora 

[](https://www.expedia.ca/Puerto-Ayora-Hotels-FAMILY-SUITE-In-Puerto-Ayora.h82555432.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(1 review)

"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nathan M.

CA $272

CA $310 total

Feb 15 - Feb 16

[](https://www.expedia.ca/Puerto-Ayora-Hotels-FAMILY-SUITE-In-Puerto-Ayora.h82555432.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-27&endDate=2026-02-28&regionId=739209696364867584&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Aparthotels

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Apartments

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Condos

[](https://www.expedia.ca/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-05-14&d1=2026-05-14&endDate=2026-05-17&d2=2026-05-17&lodging=CONDO)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-05-14&d1=2026-05-14&endDate=2026-05-17&d2=2026-05-17&lodging=VACATION_HOME)

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Isla+Santa+Mar%C3%ADa%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=739209696364867584&latLong=-1.290182%2C-90.42823&adults=2&startDate=2026-05-14&d1=2026-05-14&endDate=2026-05-17&d2=2026-05-17&lodging=CABIN)

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## Top Isla Santa María Hotel Reviews

![El Barranco Galapagos](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/910f927d_y.jpg)

### El Barranco Galapagos

10/10 Excellent

"Very helpful staff, nice clean room!"

[](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information)

![Hotel Ninfa](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08eca00e_y.jpg)

### Hotel Ninfa

10/10 Excellent

"Great spot, close to everything in "

[](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information)

![Hotel Fiesta](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/b440b32f_y.jpg)

### Hotel Fiesta

10/10 Excellent

"Great location. Staff was very friendly and helpful. Rooms were spacious and clean. Pool was refreshing after a hot day out."

[](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information)

![Galapagos Verde Azul](https://images.trvl-media.com/lodging/10000000/9580000/9577600/9577577/6a115ff5_y.jpg)

### Galapagos Verde Azul

10/10 Excellent

"Great hotel for the price"

[](https://expedia.ca/Puerto-Ayora-Hotels-Galapagos-Verde-Azul.h9577577.Hotel-Information)

![Capitan Max B&B](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48_y.jpg)

### Capitan Max B&B

10/10 Excellent

"I was feeling like in home at this place. I recommend for somebody that get an excellent service and staff. "

[](https://expedia.ca/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information)

![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/b6171efd_y.jpg)

### Hotel el descanso del Guia

10/10 Excellent

"Rooms were clean and spacious. Staff were friendly and very accommodating. Price was very reasonable. Pool was great."

[](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information)

![Galapagos Dreams](https://images.trvl-media.com/lodging/12000000/11700000/11698100/11698055/6897639d_y.jpg)

### Galapagos Dreams

10/10 Excellent

"Friendly, helpful staff. Good hot breakfast."

[](https://expedia.ca/Puerto-Ayora-Hotels-GALAPAGOS-DREAMS.h11698055.Hotel-Information)

![Fernandina Hotel & Spa Galápagos](https://images.trvl-media.com/lodging/91000000/90030000/90029600/90029511/27a5429e_y.jpg)

### Fernandina Hotel & Spa Galápagos

10/10 Excellent

"Great staff! Cute room and pool/hot tub"

[](https://expedia.ca/Puerto-Ayora-Hotels-HOTEL-FERNANDINA.h90029511.Hotel-Information)

![Blu Galapagos Sustainable Waterfront Lodge](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e_y.jpg)

### Blu Galapagos Sustainable Waterfront Lodge

10/10 Excellent

"Great room with amazing view. Incredible service "

[](https://expedia.ca/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information)

## Find out more about Isla Santa María

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Isla Santa María. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

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- [Québec Vacation Rentals ](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals)

## Frequently asked questions

### Can I find vacation rentals in Isla Santa María?

### What are some of the best vacation rentals that Isla Santa María has to offer?

### What’s there to see and do in Isla Santa María?

### What’s a vacation rental in Isla Santa María like?

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