Large rocks and a sandy beach with sparse vegetation.

Isla Santa María Vacation Rentals

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Our top choices for Isla Santa María vacation rentals

1. Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (27 reviews)
"The host was so nice, kind, and friendly."
United States
Maho
The price is CA $180
CA $180 total
Aug 26 - Aug 27
Torre Mar Galapagos Boutique Suites

2. Suites

Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (24 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is CA $104
CA $115 total
Aug 26 - Aug 27
Suites

3. Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is CA $155
CA $210 total
Aug 28 - Aug 29
Modern apartment with 18 feet ceilings and private terrace with view to a park

4. Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is CA $111
CA $132 total
Aug 26 - Aug 27
Villa Galapagos

5. Galapagos Family Vacation 3 BR. Centrally located and Ocean View

Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Puerto Ayora
10.0 out of 10, Exceptional, (28 reviews)
"Great communication with host, gave us information ahead of time for laundry services and taxi. Clean and wonderful property close to everything and great views."
United States
Amanda
The price is CA $392
CA $691 total
Sep 14 - Sep 15
Galapagos Family Vacation 3 BR. Centrally located and Ocean View

6. Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is CA $211
CA $299 total
Aug 26 - Aug 27
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

7. Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is CA $138
CA $186 total
Aug 26 - Aug 27
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

8. TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is CA $95
CA $137 total
Aug 26 - Aug 27
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

9. Suite with spectacular ocean view, you will wake up to the sound of the sea.

Suite with spectacular ocean view, you will wake up to the sound of the sea.
Puerto Ayora
8.0 out of 10, Very good, (1 review)
The price is CA $124
CA $211 total
Aug 31 - Sep 1
Suite with spectacular ocean view, you will wake up to the sound of the sea.

10. Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
2.0 out of 10, (1 review)
"Beware of this scam, the owner did not receive our reservstion nor the money!"
United States
Maya
The price is CA $205
CA $233 total
Aug 26 - Aug 27
Galapagos Coliving Ecuador Casa Tuna

11. 2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is CA $94
CA $121 total
Aug 26 - Aug 27
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

12. FAMILY SUITE in Puerto Ayora

FAMILY SUITE in Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."
United States
Nathan M.
The price is CA $275
CA $312 total
Aug 26 - Aug 27
FAMILY SUITE in Puerto Ayora

13. Pinzón Apartment in Puerto Ayora

Pinzón Apartment in Puerto Ayora
Puerto Ayora
The price is CA $83
CA $122 total
Sep 6 - Sep 7
Pinzón Apartment in Puerto Ayora

14. Near Tortuga Bay Beach

Near Tortuga Bay Beach
Puerto Ayora
The price is CA $69
CA $107 total
Sep 5 - Sep 6
Near Tortuga Bay Beach

15. Dominga Terrace

Dominga Terrace
Unknown
The price is CA $73
CA $135 total
Sep 6 - Sep 7
Dominga Terrace

16. TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is CA $95
CA $137 total
Sep 5 - Sep 6
TWO Bedrooms Apartment ON THE First Floor Forest View

17. NEAR THE SEE-DARWIN APARTMENT

NEAR THE SEE-DARWIN APARTMENT
Puerto Ayora
The price is CA $124
CA $170 total
Aug 27 - Aug 28
NEAR THE SEE-DARWIN APARTMENT

18. Near the sea-Darwin Apartment

Near the sea-Darwin Apartment
Puerto Ayora
The price is CA $96
CA $138 total
Aug 27 - Aug 28
Near the sea-Darwin Apartment

19. ¡Bienvenido a tu hogar isleño en Galápagos!

¡Bienvenido a tu hogar isleño en Galápagos!
Puerto Ayora
The price is CA $113
CA $140 total
Aug 27 - Aug 28
¡Bienvenido a tu hogar isleño en Galápagos!

20. Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
The price is CA $113
CA $140 total
Aug 26 - Aug 27
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isla Santa María Hotel Reviews

Find out more about Isla Santa María

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Isla Santa María. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Isla Santa María?

Yes, we have vacation rentals in Isla Santa María near Galápagos National Park, or you can go with a more secluded option if you're looking for extra privacy while you relax.

What are some of the best vacation rentals that Isla Santa María has to offer?

Villa Galapagos: Visitors like this Isla Santa María vacation home rental. It is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What’s there to see and do in Isla Santa María?

Family-friendly attractions include Galápagos National Park, whereas Post Office Bay is a spot to enjoy the outdoors. Other places in town to visit include Punta Suarez.

What’s a vacation rental in Isla Santa María like?

Vacation rentals are private accommodations you can stay in for several days or longer in Isla Santa María. Vacation rentals provide amenities such as WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from public hotel elevators and busy reception areas while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family trip.