Find hotels in Isla Santa María from CA $63

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Feb 14 - Feb 15
Tomorrow
Feb 15 - Feb 16
Next weekend
Feb 20 - Feb 22
In two weeks
Feb 27 - Mar 1

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Isla Santa María hotels

Interior

PENGUIN HOSTEL

PENGUIN HOSTEL
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"Love the stay, very welcoming atmosphere, wonderful owners, I recommend this to everyone"
United States
LEO
The price is CA $33
CA $68 total
Feb 15 - Feb 16
PENGUIN HOSTEL
Terrace/patio

ECO HOSTAL ISLA AZUL

ECO HOSTAL ISLA AZUL
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"Loved that they had purified water to refill your water bottle instead of buying plastic! Staff were incredibly kind. "
Canada
Jaclyn
The price is CA $191
CA $249 total
Feb 15 - Feb 16
ECO HOSTAL ISLA AZUL
Breakfast, dinner served; local and international cuisine, ocean views

Ikala Galapagos Hotel

Ikala Galapagos Hotel
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (131 reviews)
"Gorgeous property and wonderful staff!"
United States
Robyn
The price is CA $301
CA $331 total
Feb 15 - Feb 16
Ikala Galapagos Hotel
Terrace/patio

Hotel Cucuve

Hotel Cucuve
4.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (274 reviews)
"Best place we stayed at in Ecuador. Clean, friendly and affordable. "
United States
Djoanna
The price is CA $270
CA $297 total
Feb 15 - Feb 16
Hotel Cucuve
Exterior

Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (130 reviews)
"Very clean room, great staff and excellent location."
United States
Tomasz
The price is CA $383
CA $422 total
Feb 15 - Feb 16
Angermeyer Waterfront Inn
Front of property

Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (125 reviews)
"Beautiful property "
Canada
David
The price is CA $301
CA $331 total
Feb 26 - Feb 27
Blu Galapagos Sustainable Waterfront Lodge
Exterior

Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
4.5 star property
Puerto Ayora
9.2 out of 10, Wonderful, (93 reviews)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"
United States
Jonathan
The price is CA $765
CA $850 total
Mar 17 - Mar 18
Finch Bay Galapagos Hotel
Terrace/patio

Hotel La Casa de Judy

Hotel La Casa de Judy
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (166 reviews)
"We received an upgrade on the room with an ocean view. The room was clean, the staff friendly, breakfast was good, and the place is convenient to a laundry place and the downtown as well as the Darwin research center. "
United States
Heidi
The price is CA $129
CA $150 total
Mar 15 - Mar 16
Hotel La Casa de Judy
Standard Triple Room

Capitan Max B&B

Capitan Max B&B
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (211 reviews)
"Clean , friendly staff, accommodating "
United States
Anna
Capitan Max B&B
Living area

El Barranco Galapagos

El Barranco Galapagos
2.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (44 reviews)
"Very comfortable hotel with good service and nice staff."
United States
jairo
The price is CA $247
CA $247 total
Feb 24 - Feb 25
El Barranco Galapagos
Family Suite | Balcony view

Posada del Mar

Posada del Mar
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (219 reviews)
"This place is amazing, I only came across the lounge and kitchen on the higher floor on my second day but by far the best room during my trip"
United States
Sharath
The price is CA $96
CA $96 total
Feb 15 - Feb 16
Posada del Mar
Outdoor pool

Maidith Galapagos Inn

Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (110 reviews)
"Overall excellent choice for a family stay in Puerto Ayora. Rooms are very clean and spacious and short walk to main ferry pier and lots of restaurants and shopping. "
United States
Aaron
The price is CA $172
CA $172 total
Feb 24 - Feb 25
Maidith Galapagos Inn
Jetted tub

Hotel Fiesta

Hotel Fiesta
3.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (390 reviews)
"Perfect place to stay "
United States
Carol
The price is CA $211
CA $211 total
Feb 20 - Feb 21
Hotel Fiesta
Beach nearby, white sand

Hotel Ninfa

Hotel Ninfa
3.5 star property
Puerto Ayora
8.4 out of 10, Very good, (225 reviews)
"Great, clean, and convenient place. Good location close to docks. Walkable to the Main Street. Hotel rooms clean with good service and breakfast. We stayed here two seperate times during Galapagos and would stay again. "
Canada
Aly
Hotel Ninfa
Water view

Twin Hotel Galapagos

Twin Hotel Galapagos
3.0 star property
Bella Vista
8.4 out of 10, Very good, (45 reviews)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
Canada
Chelsea
The price is CA $125
CA $125 total
Mar 15 - Mar 16
Twin Hotel Galapagos
Outdoor pool

Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (32 reviews)
"Great staff! Cute room and pool/hot tub"
United States
Andrew
The price is CA $204
CA $204 total
Feb 19 - Feb 20
Fernandina Hotel & Spa Galápagos
Exterior

Mainao

Mainao
3.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (35 reviews)
"Great place to stay"
United States
Pavel
The price is CA $213
CA $234 total
Mar 2 - Mar 3
Mainao
Interior

Hotel el descanso del Guia

Hotel el descanso del Guia
3.5 star property
Puerto Ayora
8.8 out of 10, Excellent, (189 reviews)
"Rooms were clean and spacious. Staff were friendly and very accommodating. Price was very reasonable. Pool was great."
Canada
Michael
The price is CA $93
CA $93 total
Mar 3 - Mar 4
Hotel el descanso del Guia
Dining

Grand Hotel Leon Marino Galapagos

Grand Hotel Leon Marino Galapagos
3.0 star property
Puerto Ayora
8.6 out of 10, Excellent, (17 reviews)
"Staff was very friendly and location convenient. Modern interior."
United Kingdom
Marc
The price is CA $126
CA $126 total
Feb 16 - Feb 17
Grand Hotel Leon Marino Galapagos
Garden view

Galapagos Dreams

Galapagos Dreams
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (128 reviews)
"Friendly, helpful staff. Good hot breakfast."
United States
Tony
Galapagos Dreams
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Isla Santa María attractions

Swimming with sea turtles was one of the many amazing moments of my Galapagos adventure. Like most of the other animals, they went about their business without seeming to even notice the people around.
Photo by Tove Martin
Open Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
See properties
Bedtime in the Galapagos #golden
Photo by Delen Wong
Open Photo by Delen Wong

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
See properties

Learn more about Isla Santa María

Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María.

See all hotels in Isla Santa María
Sea lions soaking in some rays on the island of espanola in the Galapagos. Unfortunately no mai tai's on this beach. #LifeAtExpedia #nature
Photo by Delen Wong
Open Photo by Delen Wong

Top Isla Santa María Hotel Reviews

Posada del Mar

Posada del Mar

10/10 Excellent
"The room was adequate but the amenities were terrific. We were catching a later ferry and they stored our luggage and allowed us to use the facilities until we left for the ferry. "
Mari-Lee 1-night trip
Posted 18 hours ago
Posada del Mar

More cheap stays in Isla Santa María

Hostal Casa Cascada

Hostal Casa Cascada

Pje. 1 Puerto Ayora Galápagos Islands
The price is CA $32 per night from Mar 5 to Mar 6
CA $32
CA $63 total
Mar 5 - Mar 6
9.6/10 Exceptional! (5 reviews)

Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Maidith Galapagos Inn and Ikala Galapagos Hotel. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best vacation rentals that Isla Santa María has to offer?
Villa Galapagos: Located near Isla Santa María, this vacation home rental is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
What is staying in Isla Santa María like?
Travelers to Isla Santa María will find plenty to explore and enjoy. There are 210 hotels and other accommodations in larger region. Find out more about Isla Santa María.
What should I see while I'm in Isla Santa María?
Favorite places to visit include Galápagos National Park, Post Office Bay, and Punta Suarez. Check out what more to see and do in Expedia's Isla Santa María guide.
What's the weather like in Isla Santa María?
The hottest months are usually March and February with an average temp of 79°F, while the coldest months are September and October with an average of 72°F. Average annual precipitation for Isla Santa María is 13 inches.