Large rocks and a sandy beach with sparse vegetation.

Isla Santa María Vacation Rentals

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Our top choices for Isla Santa María vacation rentals

Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.2 out of 10, Wonderful, (24 reviews)
"Place was spotless! Very accommodating and helpful staff."
Canada
Nicholas
The price is CA $186
CA $186 total
Jul 6 - Jul 7
Torre Mar Galapagos Boutique Suites

Suites

Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (24 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is CA $107
CA $118 total
Jul 2 - Jul 3
Suites

Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is CA $128
CA $149 total
Jul 2 - Jul 3
Villa Galapagos

Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
The price is CA $153
CA $182 total
Jul 20 - Jul 21
Galapagos Coliving Ecuador Casa Tuna

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is CA $97
CA $125 total
Jul 2 - Jul 3
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (23 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is CA $160
CA $216 total
Jul 4 - Jul 5
Modern apartment with 18 feet ceilings and private terrace with view to a park

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is CA $217
CA $309 total
Jul 8 - Jul 9
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is CA $98
CA $141 total
Jul 2 - Jul 3
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

Pinzón Apartment in Puerto Ayora

Pinzón Apartment in Puerto Ayora
Puerto Ayora
The price is CA $85
CA $126 total
Jul 7 - Jul 8
Pinzón Apartment in Puerto Ayora

Galarous Island Suite comfortable and cozy

Galarous Island Suite comfortable and cozy
Puerto Ayora
The price is CA $54
CA $82 total
Jul 2 - Jul 3
Galarous Island Suite comfortable and cozy

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is CA $142
CA $192 total
Jul 2 - Jul 3
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Five minutes from the Malecon Santa Cruz - Puerto Ayora.

Five minutes from the Malecon Santa Cruz - Puerto Ayora.
Puerto Ayora
The price is CA $166
CA $248 total
Jul 2 - Jul 3
Five minutes from the Malecon Santa Cruz - Puerto Ayora.

Comfortable and cozy Galarous Island Suite

Comfortable and cozy Galarous Island Suite
Puerto Ayora
The price is CA $128
CA $156 total
Jul 14 - Jul 15
Comfortable and cozy Galarous Island Suite

Galarous island apartments

Galarous island apartments
Puerto Ayora
The price is CA $142
CA $170 total
Jul 2 - Jul 3
Galarous island apartments

A nice place to stay with the family with spacious rooms

A nice place to stay with the family with spacious rooms
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Javier and Marí were wonderful hosts. They were gracious, helpful, and friendly. They were very accommodating and gave us a number of great recommendations of places to eat, stores to go to, and things to do. They can also set up tours as needed."
United States
Jeffrey R.
The price is CA $38
CA $72 total
Jul 6 - Jul 7
A nice place to stay with the family with spacious rooms

Galapagos Apartment-Darwin

Galapagos Apartment-Darwin
Puerto Ayora
The price is CA $85
CA $126 total
Jul 2 - Jul 3
Galapagos Apartment-Darwin

Galarous serve you with quality and warmth in your home

Galarous serve you with quality and warmth in your home
Puerto Ayora
The price is CA $114
CA $142 total
Jul 2 - Jul 3
Galarous serve you with quality and warmth in your home

TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is CA $98
CA $141 total
Jul 3 - Jul 4
TWO Bedrooms Apartment ON THE First Floor Forest View

Near the sea-Darwin Apartment

Near the sea-Darwin Apartment
Puerto Ayora
The price is CA $99
CA $143 total
Jul 2 - Jul 3
Near the sea-Darwin Apartment

Dominga Terrace

Dominga Terrace
Unknown
The price is CA $78
CA $141 total
Jul 14 - Jul 15
Dominga Terrace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isla Santa María Hotel Reviews

Find out more about Isla Santa María

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Isla Santa María. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Isla Santa María?

Yes, we have vacation rentals in Isla Santa María near Galápagos National Park, or you can go with a more secluded option if you're looking for extra privacy while you relax.

What are some of the best vacation rentals that Isla Santa María has to offer?

Villa Galapagos: Visitors like this Isla Santa María vacation home rental. It is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What’s there to see and do in Isla Santa María?

Family-friendly attractions include Galápagos National Park, whereas Post Office Bay is a spot to enjoy the outdoors. Other places in town to visit include Punta Suarez.

What’s a vacation rental in Isla Santa María like?

Vacation rentals are private accommodations you can stay in for several days or longer in Isla Santa María. Vacation rentals provide amenities such as WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from public hotel elevators and busy reception areas while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family trip.