A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Our top choices for Defiance apartments

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
The price is CA $194
CA $256 total
includes taxes & fees
Oct 11 - Oct 12
Great for Business Travelers! Pool + Gym

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is CA $100
CA $343 total
includes taxes & fees
Sep 16 - Sep 17
Stylish1BRStudioCleanQuietandCozy

3. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (9 reviews)
"Great comfortable mini apartment style."
United States
Ozzy
The price is CA $126
CA $259 total
includes taxes & fees
Sep 23 - Sep 24
2nd Street -Deck Suite (back entrance)

4. Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
Ballwin
7.8 out of 10, Good, (23 reviews)
"Rooms were clean and everything we needed for our stay."
United States
Keith K.
The price is CA $94
CA $205 total
includes taxes & fees
Sep 20 - Sep 21
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

5. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (17 reviews)
"Beautiful loft! Great location, walking distance to several restaurants on the river . "
United States
Christy D.
The price is CA $119
CA $242 total
includes taxes & fees
Sep 23 - Sep 24
2nd Street Loft - Riverview

6. Otto's Third | River View Loft by Borgia Church

Otto's Third | River View Loft by Borgia Church
Washington
The price is CA $422
CA $538 total
includes taxes & fees
Sep 16 - Sep 17
Otto's Third | River View Loft by Borgia Church

7. Family Friendly w/ Game Room in Quiet Neighborhood

Family Friendly w/ Game Room in Quiet Neighborhood
Wentzville
10.0 out of 10, Exceptional, (2 reviews)
"Nice house for our week in Lake St. Louis area. Accurate description of what you are getting and clean house. Would stay again if we are back in the area"
United States
Campbell W.
The price is CA $313
CA $669 total
includes taxes & fees
Sep 17 - Sep 18
Family Friendly w/ Game Room in Quiet Neighborhood

8. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.6 out of 10, Exceptional, (41 reviews)
"Great spot!"
United States
Anonymous traveller
The price is CA $82
CA $95 total
includes taxes & fees
Oct 4 - Oct 5
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

9. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is CA $141
CA $390 total
includes taxes & fees
Sep 17 - Sep 18
Dog-Friendly 2BR | Walk to Main Street

10. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (38 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is CA $143
CA $313 total
includes taxes & fees
Sep 20 - Sep 21
Historic Main Street Studio | Dog-Friendly

11. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
The price is CA $123
CA $379 total
includes taxes & fees
Sep 16 - Sep 17
6th street 101 - Walk to Main St

12. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (42 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
The price is CA $192
CA $580 total
includes taxes & fees
Sep 20 - Sep 21
Historic Main St 2BR | Steps to Shops

13. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (190 reviews)
"It was great! Clean and great communication with host."
United States
Natalie H.
The price is CA $155
CA $339 total
includes taxes & fees
Sep 16 - Sep 17
The Lofts of North Main Street

14. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is CA $124
CA $333 total
includes taxes & fees
Sep 16 - Sep 17
1st Capitol Mansion - Suite 401

15. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (117 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveller
The price is CA $135
CA $314 total
includes taxes & fees
Sep 16 - Sep 17
Prime Loft of Main Street

16. Main Street 2BR - Walk to Dining & Riverfront

Main Street 2BR - Walk to Dining & Riverfront
St. Charles Historic District
9.4 out of 10, Exceptional, (3 reviews)
"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"
United States
Billi G.
The price is CA $185
CA $459 total
includes taxes & fees
Sep 20 - Sep 21
Main Street 2BR - Walk to Dining & Riverfront

17. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
10.0 out of 10, Exceptional, (11 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
The price is CA $177
CA $386 total
includes taxes & fees
Sep 20 - Sep 21
Walk to Main | Pet-Friendly Yard & Workspace

18. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is CA $208
CA $534 total
includes taxes & fees
Sep 28 - Sep 29
Historic Main St. Customs House Upstairs Apartment

19. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (68 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is CA $193
CA $387 total
includes taxes & fees
Sep 20 - Sep 21
Amazing Renovated Historic Loft on Main Street

20. Historic Main St 1BR | Walk to Dining & Nightlife

Historic Main St 1BR | Walk to Dining & Nightlife
St. Charles Historic District
9.2 out of 10, Wonderful, (24 reviews)
"Great place, very fun. I’d stay again for sure. "
United States
Michael C.
The price is CA $188
CA $372 total
includes taxes & fees
Sep 17 - Sep 18
Historic Main St 1BR | Walk to Dining & Nightlife
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Apartments information

Number of reviews
609
Accommodation
113 Apartments
Lowest Price
CA $95
Highest Price
CA $669

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights, 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and Smart TVs. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: Located 18.7 mi/30.1 km away in Maryland Heights. Free WiFi and Smart TVs are included. The Lofts of North Main Street: Located in St. Charles, 19.2 mi/30.8 km away. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. Driftwood Den | Boho 2BR | Dog-Friendly: 19 mi/30.6 km away in St. Charles. Amenities include free WiFi. Historic Main Street Studio | Dog-Friendly: It's situated in St. Charles, 19.1 mi/30.8 km from Defiance.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.

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