Greene County Vacation Rentals

Compare and save

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Aug 15 - Aug 17
In two weeks
Aug 22 - Aug 24
In one month
Sep 5 - Sep 7
In two months
Oct 3 - Oct 5

Featured Vacation Homes in Greene County

Grafton Escape #2 - River views! Pool! Walking distance to bars/restaurants
Relax on the deck with a scenic view of the water and city skyline.

Grafton Escape #2 - River views! Pool! Walking distance to bars/restaurants

10.0 out of 10, Exceptional, (68)
"Perfect location and set up for ourselves and another couple. Michelle is an awesome hoey"
Grafton Escape #2 - River views! Pool! Walking distance to bars/restaurants
Charming Escape in Grafton!
Relax in this serene sunroom with a view of the lake and grassy field, featuring a sofa, chair, and round table with a plant.

Charming Escape in Grafton!

10.0 out of 10, Exceptional, (9)
"Great location, very nice, clean, with everything you need. I wish the weather would have been a little better. We would definitely stay again. "
Charming Escape in Grafton!
Charming 3BR/2BA home—peaceful country vibes, perfect for relaxing stays!
Relax in a spacious living area with a tufted sofa and ceiling fan, offering a comfortable seating space and a view of the outdoors.

Charming 3BR/2BA home—peaceful country vibes, perfect for relaxing stays!

6.8 out of 10, (3)
"The house was great and Nicole was a great host. "
Charming 3BR/2BA home—peaceful country vibes, perfect for relaxing stays!
Escape the city to quiet and picturesque Golden Eagle, IL..
Enjoy a spacious kitchen with a central island and bar stools, complemented by a cozy seating area with a sofa and chairs.

Escape the city to quiet and picturesque Golden Eagle, IL..

10.0 out of 10, Exceptional, (353)
"We had such a great time staying at the red barn. Everything was awesome and we enjoyed the atmosphere and peace and quiet while we were there. Thanks again for your hospitality "
Escape the city to quiet and picturesque Golden Eagle, IL..
McClusky Trail Guesthouse Convenient Access to Jerseyville, Grafton & Alton
Compact kitchen with appliances, including a microwave, stove, and sink, and a small dining area with two chairs.

McClusky Trail Guesthouse Convenient Access to Jerseyville, Grafton & Alton

10.0 out of 10, Exceptional, (18)
"Adorable place and great communication with the owner! "
The price is CA $146
CA $301 total
includes taxes & fees
Aug 11 - Aug 12
McClusky Trail Guesthouse Convenient Access to Jerseyville, Grafton & Alton
A perfect weekend gateway!
Relax on the patio surrounded by a stone wall and a metal door, with a round table and six chairs.

A perfect weekend gateway!

10.0 out of 10, Exceptional, (54)
"We love the property. Walking distance to everything. Spacious, clean, two patios to enjoy and plenty of room."
A perfect weekend gateway!
Historic Haven off the River Road
Enjoy cooking in this well-equipped kitchen with a gas stove, microwave, and large sink.

Historic Haven off the River Road

10.0 out of 10, Exceptional, (3)
"Nice area, clean house, excellent location."
Historic Haven off the River Road
Charming upper level of 3-bedroom house in Grafton, IL
Enjoy cooking in this well-equipped kitchen with a black stove, sink, and coffee bar.

Charming upper level of 3-bedroom house in Grafton, IL

10.0 out of 10, Exceptional, (1)
"The stay was phenomenal. The location was a block away from everything. Restaurants, bars, shops, and gas stations were accessible within a rock’s throw. The host was there if I needed her. The house was perfect for me and my group. Everyone was very impressed."
The price is CA $447
CA $833 total
includes taxes & fees
Aug 11 - Aug 12
Charming upper level of 3-bedroom house in Grafton, IL
Farmhouse 80 Acres Rec Room Peddle Boat Lake Fishing Nature Trl 2 ml to Grafton
Relax in this traditional room with a dining table, comfortable chair, and plush rug.

Farmhouse 80 Acres Rec Room Peddle Boat Lake Fishing Nature Trl 2 ml to Grafton

10.0 out of 10, Exceptional, (118)
"Its like coming home."
The price is CA $189
CA $352 total
includes taxes & fees
Aug 13 - Aug 14
Farmhouse 80 Acres Rec Room Peddle Boat Lake Fishing Nature Trl 2 ml to Grafton
RAFTON INN VACATION RENTAL
Enjoy cooking in this well-lit kitchen with a stainless steel refrigerator, oven, and microwave.

RAFTON INN VACATION RENTAL

9.4 out of 10, Exceptional, (10)
"Best place we have stayed in Grafton so far! Easy walk location to everything! We were very pleased with this VRBO!"
RAFTON INN VACATION RENTAL
Plainview Vineyard Retreat by StayLage
Welcome to the charming Fasting Room of Plainview Vineyard, featuring a traditional design with a cozy porch and a unique wine bottle sculpture.

Plainview Vineyard Retreat by StayLage

2.0 star property
10.0 out of 10, Exceptional, (1)
"Quiet place to relax after a long day. Clean and will rent again if given the choice. "
The price is CA $146
CA $602 total
includes taxes & fees
Aug 12 - Aug 13
Plainview Vineyard Retreat by StayLage
Victorian Carlinville home on Rt. 66
Relax on the classic porch with two comfortable chairs and a small table, surrounded by lush greenery and a charming door.

Victorian Carlinville home on Rt. 66

10.0 out of 10, Exceptional, (8)
"We will stay there again if we're in the area."
Victorian Carlinville home on Rt. 66
Walk to Mississippi River: Grafton Townhome!
Fridge, microwave, stovetop, dishwasher

Walk to Mississippi River: Grafton Townhome!

10.0 out of 10, Exceptional, (1)
"Beautiful property, very clean and the beds were comfortable! We will definitely be back! "
Walk to Mississippi River: Grafton Townhome!
PICKLEBALL, Heated Pool, Game Room, Outdoor Oasis, Tennis, Basketball, & woods!
Relax by the serene fountain and enjoy the pool area with lounge chairs and potted plants.

PICKLEBALL, Heated Pool, Game Room, Outdoor Oasis, Tennis, Basketball, & woods!

9.8 out of 10, Exceptional, (77)
"Fabulous"
PICKLEBALL, Heated Pool, Game Room, Outdoor Oasis, Tennis, Basketball, & woods!
4-Bdrm 3 bath house in Grafton with large patio, WiFi and very walkable. Fun!!!
Outdoor dining

4-Bdrm 3 bath house in Grafton with large patio, WiFi and very walkable. Fun!!!

10.0 out of 10, Exceptional, (2)
"The place is perfect for anything you want to do on Main Street. Great Food, Shopping, atmosphere. Loved coming back and enjoying our nights on the deck."
4-Bdrm 3 bath house in Grafton with large patio, WiFi and very walkable. Fun!!!
Confluence Cabin Grafton, IL
Surrounded by lush greenery, this cabin-style building offers a porch and deck with outdoor lighting.

Confluence Cabin Grafton, IL

9.8 out of 10, Exceptional, (36)
"I’d recommend for a place to stay in Grafton "
Confluence Cabin Grafton, IL
Riverside Home - Modern meets comfort
Relax in this stylish living room with a sofa, armchair, and flat-screen TV.

Riverside Home - Modern meets comfort

10.0 out of 10, Exceptional, (52)
"Great property for a quick stay."
The price is CA $186
CA $472 total
includes taxes & fees
Aug 12 - Aug 13
Riverside Home - Modern meets comfort
River Life Landing - Cozy, Relaxing home along Mississippi River - Grafton, IL
Enjoy a serene outdoor space with a picnic table and comfortable seating, surrounded by a railing and overlooking a body of water.

River Life Landing - Cozy, Relaxing home along Mississippi River - Grafton, IL

River Life Landing - Cozy, Relaxing home along Mississippi River - Grafton, IL
Peace on the Prairie Too - Tiny House, Pets Allowed, No cleaning fee.
Enjoy cooking in this well-equipped kitchen with a microwave, oven, and dishwasher.

Peace on the Prairie Too - Tiny House, Pets Allowed, No cleaning fee.

9.8 out of 10, Exceptional, (52)
"House was clean with lots of stuff to do! Very quiet get away"
The price is CA $136
CA $174 total
includes taxes & fees
Aug 14 - Aug 15
Peace on the Prairie Too - Tiny House, Pets Allowed, No cleaning fee.
1870's Estate Style Home with private courtyard.
Outdoor dining

1870's Estate Style Home with private courtyard.

10.0 out of 10, Exceptional, (6)
"Very friendly host and beautiful home. Perfect location for a stay in Grafton "
1870's Estate Style Home with private courtyard.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Greene County Hotel Reviews

William Watson Hotel

William Watson Hotel

10/10 Excellent
"Nice comfortable place and close to family "
Robert 1-night trip
Posted 5 days ago
William Watson Hotel