Photo by Michael Schuier

Find hotels in South Carolina Lowcountry, SC from CA $84
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in South Carolina Lowcountry
Check prices for these dates
Our top choices for South Carolina Lowcountry hotels

Microtel Inn & Suites by Wyndham Walterboro
Microtel Inn & Suites by Wyndham WalterboroWalterboro
8.0 out of 10, Very good, (1,011 reviews)
The price is CA $131
CA $147 total
includes taxes & fees
Apr 7 - Apr 8

OYO Hampton South Carolina Hwy 278
OYO Hampton South Carolina Hwy 278Hampton
8.4 out of 10, Very good, (107 reviews)
The price is CA $136
CA $167 total
includes taxes & fees
Mar 31 - Apr 1

Beaufort Inn
Beaufort InnDowntown Beaufort
9.0 out of 10, Wonderful, (1,002 reviews)
The price is CA $261
CA $309 total
includes taxes & fees
Apr 5 - Apr 6

Hampton Inn Hardeeville
Hampton Inn HardeevilleHardeeville
8.8 out of 10, Excellent, (279 reviews)
The price is CA $158
CA $179 total
includes taxes & fees
Apr 5 - Apr 6

Comfort Inn & Suites Walterboro I-95
Comfort Inn & Suites Walterboro I-95Walterboro
8.4 out of 10, Very good, (1,008 reviews)
The price is CA $156
CA $174 total
includes taxes & fees
Apr 19 - Apr 20

Fairfield by Marriott Inn & Suites Hardeeville I-95
Fairfield by Marriott Inn & Suites Hardeeville I-95Hardeeville
9.0 out of 10, Wonderful, (332 reviews)
The price is CA $164
CA $185 total
includes taxes & fees
Apr 12 - Apr 13

Hilton Garden Inn Hilton Head
Hilton Garden Inn Hilton HeadHilton Head Island
8.6 out of 10, Excellent, (1,004 reviews)
The price is CA $170
CA $187 total
includes taxes & fees
Apr 12 - Apr 13

Motel 6 Walterboro, SC
Motel 6 Walterboro, SCWalterboro
8.2 out of 10, Very good, (1,402 reviews)
The price is CA $83
CA $93 total
includes taxes & fees
Apr 1 - Apr 2

Palmera Inn and Suites
Palmera Inn and SuitesSouth End
9.0 out of 10, Wonderful, (1,240 reviews)
The price is CA $145
CA $192 total
includes taxes & fees
Apr 19 - Apr 20

Holiday Inn Express Bluffton at Hilton Head Area by IHG
Holiday Inn Express Bluffton at Hilton Head Area by IHGBluffton
9.0 out of 10, Wonderful, (1,004 reviews)
The price is CA $176
CA $194 total
includes taxes & fees
Apr 12 - Apr 13

Best Western Plus Bluffton / Hilton Head Hotel
Best Western Plus Bluffton / Hilton Head HotelBluffton
9.4 out of 10, Exceptional, (191 reviews)
The price is CA $177
CA $194 total
includes taxes & fees
Apr 19 - Apr 20

SpringHill Suites by Marriott Beaufort
SpringHill Suites by Marriott BeaufortBeaufort
9.4 out of 10, Exceptional, (1,023 reviews)
The price is CA $171
CA $188 total
includes taxes & fees
Apr 4 - Apr 5

Spark by Hilton Bluffton Hilton Head Island
Spark by Hilton Bluffton Hilton Head IslandBelfair
8.6 out of 10, Excellent, (189 reviews)
The price is CA $126
CA $139 total
includes taxes & fees
Apr 5 - Apr 6

Hampton Inn Yemassee/Point South
Hampton Inn Yemassee/Point SouthYemassee
8.8 out of 10, Excellent, (800 reviews)
The price is CA $189
CA $214 total
includes taxes & fees
Apr 12 - Apr 13

Tru by Hilton Beaufort, SC
Tru by Hilton Beaufort, SCBeaufort
9.0 out of 10, Wonderful, (767 reviews)
The price is CA $139
CA $153 total
includes taxes & fees
Apr 6 - Apr 7

Hilton Beachfront Resort & Spa Hilton Head Island
Hilton Beachfront Resort & Spa Hilton Head IslandMid Island
8.4 out of 10, Very good, (1,433 reviews)
The price is CA $295
CA $378 total
includes taxes & fees
Apr 12 - Apr 13

The Westin Hilton Head Island Resort & Spa
The Westin Hilton Head Island Resort & SpaMid Island
8.4 out of 10, Very good, (1,006 reviews)
The price is CA $261
CA $351 total
includes taxes & fees
Apr 12 - Apr 13

Best Western Plus Hardeeville Inn & Suites
Best Western Plus Hardeeville Inn & SuitesHardeeville
8.4 out of 10, Very good, (1,006 reviews)
The price is CA $142
CA $160 total
includes taxes & fees
Apr 1 - Apr 2

Best Western Of Walterboro
Best Western Of WalterboroWalterboro
7.6 out of 10, Good, (387 reviews)
The price is CA $153
CA $171 total
includes taxes & fees
Apr 1 - Apr 2

Holiday Inn Exp Walterboro by IHG
Holiday Inn Exp Walterboro by IHGWalterboro
8.6 out of 10, Excellent, (1,003 reviews)
The price is CA $224
CA $251 total
includes taxes & fees
Apr 19 - Apr 20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in South Carolina Lowcountry
Aparthotel

Bluewater Resort & Marina by Spinnaker Resorts
Bluewater Resort & Marina by Spinnaker ResortsNorth End
9.6 out of 10, Exceptional, (142 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southeastern United States attractions
Learn more about South Carolina Lowcountry
Head to sights like Highway 21 Drive-In Theater and Beaufort National Cemetery as you discover South Carolina Lowcountry.

Photo by Michael Schuier
Open Photo by Michael Schuier
Top South Carolina Lowcountry Hotel Reviews
Recent Reviews in South Carolina Lowcountry

Sonesta Resort Hilton Head Island
10/10 Excellent
More cheap stays in South Carolina Lowcountry

Red Roof Inn Hardeeville
1122 Hummingbird Lane Hardeeville SC
The price is CA $74 per night from Mar 31 to Apr 1
CA $74
CA $84 total
Mar 31 - Apr 1
includes taxes & fees
8/10 Very Good! (1,532 reviews)
Hotels in South Carolina Lowcountry with star rating

5 Star Hotels
3 properties
Explore a world of travel with Expedia
- Hotels near Bay Street
- Beaufort Hotels
- Guest Houses in Burton
- Beach Hotel Hotels in Burton
- Burton Hotels
- Inns in Burton
- Vacation Homes in Burton
- Resorts in Burton
- B&B in Coosawatchie
- Coosawatchie Hotels
- Beaufort County Hotels
- Colleton County Hotels
- Downtown Beaufort Hotels
- Inns in Gardens Corner
- Green Pond Hotels
- Resorts in Green Pond
- Habersham Hotels
- Hendersonville Hotels
- Hotels near Henry C. Chambers Waterfront Park
- Hotels near Highway 21 Drive-In Theater
- Beach Hotel Hotels in Historic District
- Boutique Hotels in Historic District
- Hotels with Kitchenettes in Historic District
- Pet-Friendly Hotels in Historic District
- Spa Hotels in Historic District
- Historic District Hotels
- Historic Downtown Hotels
- Cheap Hotels in Jacksonboro
- Luxury Hotels in Jacksonboro
- Jacksonboro Hotels
- Resorts in Jacksonboro
- Adults Only Resorts & in Ladys Island
- Honeymoon Resorts and in Ladys Island
- Ladys Island Hotels
- Inns in Ladys Island
- Resorts in Ladys Island
- B&B in Laurel Bay
- Laurel Bay Hotels
- Inns in Laurel Bay
- Motels in Laurel Bay
- Lobeco Hotels
- Hotels near Marine Corps Air Station Beaufort
- Adults Only Resorts & in Pigeon Point
- All Inclusive Resorts and in Pigeon Point
- Beach Hotel Hotels in Pigeon Point
- Cheap Hotels in Pigeon Point
- Hotels with Waterslides in Pigeon Point
- Pet-Friendly Hotels in Pigeon Point
- Pigeon Point Hotels
- Farmstay in Seabrook
- Guest Houses in Seabrook
- Beach Hotel Hotels in Seabrook
- Boutique Hotels in Seabrook
- Golf Hotels in Seabrook
- Seabrook Hotels
- Inns in Seabrook
- Lodges in Seabrook
- Resorts in Seabrook
- Townhomes in Seabrook
- Sheldon Hotels
- Resorts in Sheldon
- Luxury Hotels in The Bluff
- Hotel Wedding Venues Hotels in The Bluff
- The Bluff Hotels
- Hotels near The Colleton Center
- Hotels near University of South Carolina-Beaufort
- Hotels with Wifi in Uptown
- Hotels with Kitchenettes in Uptown
- B&B in Walterboro
- Cheap Hotels in Walterboro
- Historic Hotels in Walterboro
- Hotels with a Pool in Walterboro
- Hotels with Wifi in Walterboro
- Hotels with Bar in Walterboro
- Hotels with Free Breakfast in Walterboro
- Lgbt Friendly Hotels in Walterboro
- Luxury Hotels in Walterboro
- Pet-Friendly Hotels in Walterboro
- Walterboro Hotels
- Resorts in Walterboro
- Walterboro - St. George Hotels
- Wiggins Hotels
- Cheap Hotels in Yemassee
- Hotels with Wifi in Yemassee
- Luxury Hotels in Yemassee
- Pet-Friendly Hotels in Yemassee
- Yemassee Hotels
- Hotels near Yemassee Station












































































































































