South Carolina Lowcountry Vacation Rentals

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Our top choices for South Carolina Lowcountry vacation rentals

Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Tranquility by the Beach 1st Fl Sleeps 6,King Bed
Mid Island
9.4 out of 10, Exceptional, (55 reviews)
"Nice condo. Easy walk to beach."
United States
A. D.
The price is CA $161
CA $430 total
includes taxes & fees
May 3 - May 4
Tranquility by the Beach 1st Fl Sleeps 6,King Bed

The Grey Pearl on Port Royal's Battery Creek

The Grey Pearl on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (22 reviews)
"Great property "
United States
Caleb C.
The price is CA $126
CA $281 total
includes taxes & fees
Apr 6 - Apr 7
The Grey Pearl on Port Royal's Battery Creek

Bluffton Getaway w/ Fenced Yard: 7 Mi to Beach!

Bluffton Getaway w/ Fenced Yard: 7 Mi to Beach!
3.0 star property
Edgefield
10.0 out of 10, Exceptional, (1 review)
"It was like home away frim home. "
United States
Willie
Bluffton Getaway w/ Fenced Yard: 7 Mi to Beach!

Mariners' Nautical Nest on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (31 reviews)
"We so loved our stay! Our stay was AMAZING! Great location, great views, and the downtown area is very close and easy to get to. Cannot wait to rebook your place!! "
United States
Glenn G.
The price is CA $158
CA $317 total
includes taxes & fees
Apr 21 - Apr 22
Mariners' Nautical Nest on Port Royal's Battery Creek

Gorgeous Waterfront Battery Creek Retreat

Gorgeous Waterfront Battery Creek Retreat
Beaufort
9.8 out of 10, Exceptional, (100 reviews)
"Great stay! Private, cozy, and quiet with a great view of the water and marsh."
United States
Jad
The price is CA $132
CA $288 total
includes taxes & fees
Apr 6 - Apr 7
Gorgeous Waterfront Battery Creek Retreat

Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Amazing Airstream, Beaufort, SC-Enjoy the Journey!
Beaufort
9.6 out of 10, Exceptional, (24 reviews)
"We love this place. I stay here frequently and enjoy every time. Close and convenient to everything Beaufort has to offer."
United States
Nate P.
The price is CA $124
CA $243 total
includes taxes & fees
Apr 5 - Apr 6
Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Fiddler's Cove 2BR Villa: 1 Block to Beach with Pools & Pickleball

Fiddler's Cove 2BR Villa: 1 Block to Beach with Pools & Pickleball
Mid Island
9.8 out of 10, Exceptional, (7 reviews)
"We had a great stay. The condo was clean and comfortable. Enjoyed all the amenities that were offered at the location. Short 5 minute walk to the beach. "
United States
DAVID C.
Fiddler's Cove 2BR Villa: 1 Block to Beach with Pools & Pickleball

All Inn on Edisto - Cozy Studio Condo Close to Everything

All Inn on Edisto - Cozy Studio Condo Close to Everything
Edisto Beach
9.8 out of 10, Exceptional, (156 reviews)
"Excellent cute little studio apartment. Thoroughly enjoyed coming back and resting after a long day of work."
United States
Cabell G.
The price is CA $138
CA $274 total
includes taxes & fees
Apr 15 - Apr 16
All Inn on Edisto - Cozy Studio Condo Close to Everything

Ocean Front & pool view. Hunting Island pass included

Ocean Front & pool view. Hunting Island pass included
Beachwalk
9.8 out of 10, Exceptional, (67 reviews)
"great stay at a great location "
United States
Greg B.
The price is CA $276
CA $551 total
includes taxes & fees
Apr 5 - Apr 6
Ocean Front & pool view. Hunting Island pass included

Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue

Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue
WALTERBORO
10.0 out of 10, Exceptional, (16 reviews)
"Clean room great location, beautiful stay!"
United States
Morgan K.
The price is CA $276
CA $379 total
includes taxes & fees
Apr 5 - Apr 6
Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue

Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue

Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue
Walterboro
9.6 out of 10, Exceptional, (13 reviews)
"Clean room Beautiful Highly recommend "
United States
Taylor P.
The price is CA $276
CA $379 total
includes taxes & fees
Apr 5 - Apr 6
Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue

Disney's Hilton Head Island Resort

Disney's Hilton Head Island Resort
3.5 star property
Mid Island
9.6 out of 10, Exceptional, (128 reviews)
"While the rooms are overdue a refurbishment, this place is a wondeful resort. "
United States
Chad
Disney's Hilton Head Island Resort

'wright by the Beach': Hilton Head Condo w/ Perks

'wright by the Beach': Hilton Head Condo w/ Perks
3.0 star property
Mid Island
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our stay. We loved the ocean theme at the apartment. Very clean rooms. Kids enjoyed swimming in the indoor pool, parents enjoyed hot tub and sauna especially on rainy days. They have indoor and outdoor pools. We liked walking on the boardwalk to the beach. We highly recommend this place and would love to return there again. "
United States
Victor
The price is CA $128
CA $417 total
includes taxes & fees
Apr 30 - May 1
'wright by the Beach': Hilton Head Condo w/ Perks

Charming Coastal Casa on Beaufort's Battery Creek

Charming Coastal Casa on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (45 reviews)
"Clean, cozy, and close to Parris Island!"
United States
Jeremy G.
The price is CA $187
CA $359 total
includes taxes & fees
Apr 19 - Apr 20
Charming Coastal Casa on Beaufort's Battery Creek

Modern Coastal Escape on Beaufort's Battery Creek

Modern Coastal Escape on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (36 reviews)
"Super cute condo, comfy accommodations super close to Parris Island. Way better than staying at a hotel."
United States
Kristine I.
The price is CA $191
CA $362 total
includes taxes & fees
Apr 5 - Apr 6
Modern Coastal Escape on Beaufort's Battery Creek

Heart of Historic Bluffton BEST LOCATION, Charming Cottage THIS IS THE ONE

Heart of Historic Bluffton BEST LOCATION, Charming Cottage THIS IS THE ONE
Old Town Bluffton
9.4 out of 10, Exceptional, (136 reviews)
"Property was in a great location and everything was clean."
United States
Miranda
The price is CA $244
CA $488 total
includes taxes & fees
Apr 26 - Apr 27
Heart of Historic Bluffton BEST LOCATION, Charming Cottage THIS IS THE ONE

Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown

Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown
Sea Pines
10.0 out of 10, Exceptional, (83 reviews)
"Great location!"
United States
Jessica G.
The price is CA $216
CA $534 total
includes taxes & fees
Apr 11 - Apr 12
Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown

King Suite at The Emerald, Spa Bathroom w. Robes!

King Suite at The Emerald, Spa Bathroom w. Robes!
Historic District
9.6 out of 10, Exceptional, (33 reviews)
"Wonderful stay, had everything we needed and loves the location. We will be staying here again!"
United States
Leah R.
The price is CA $164
CA $311 total
includes taxes & fees
Apr 8 - Apr 9
King Suite at The Emerald, Spa Bathroom w. Robes!

SeaClusion-Oceanview, Mini split AC, Beach Chairs

SeaClusion-Oceanview, Mini split AC, Beach Chairs
South End
9.6 out of 10, Exceptional, (61 reviews)
"Location cleanliness cozy the beach 3min walk its a great spot"
United States
kenneth
The price is CA $123
CA $374 total
includes taxes & fees
Apr 16 - Apr 17
SeaClusion-Oceanview, Mini split AC, Beach Chairs

Bluffton Retreat, Pet Friendly

Bluffton Retreat, Pet Friendly
Bluffton
10.0 out of 10, Exceptional, (21 reviews)
"Host was very responsive to our needs."
United States
Margie S.
The price is CA $271
CA $475 total
includes taxes & fees
Apr 7 - Apr 8
Bluffton Retreat, Pet Friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Lowcountry Hotel Reviews

Find out more about South Carolina Lowcountry

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with South Carolina Lowcountry. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.