A flock of birds flying in formation against a clear blue sky.

South Carolina Lowcountry Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for South Carolina Lowcountry vacation rentals

1. Gorgeous Waterfront Battery Creek Retreat

Gorgeous Waterfront Battery Creek Retreat
Beaufort
10.0 out of 10, Exceptional, (120 reviews)
"The location was lovely and made for the perfect getaway. "
United States
Jim S.
The price is CA $131
CA $287 total
includes taxes & fees
Sep 14 - Sep 15
Gorgeous Waterfront Battery Creek Retreat

2. Deluxe 2 Full Beds | Walterboro

Deluxe 2 Full Beds | Walterboro
Walterboro SC
10.0 out of 10, Exceptional, (98 reviews)
"The location is perfect for a quick getaway from Charleston."
United States
Anonymous traveller
The price is CA $85
CA $108 total
includes taxes & fees
Sep 14 - Sep 15
Deluxe 2 Full Beds | Walterboro

3. The Grey Pearl on Port Royal's Battery Creek

The Grey Pearl on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (38 reviews)
"Great property "
United States
Caleb C.
The price is CA $125
CA $279 total
includes taxes & fees
Sep 14 - Sep 15
The Grey Pearl on Port Royal's Battery Creek

4. The Drift at Port Royal on Battery Creek

The Drift at Port Royal on Battery Creek
Beaufort
10.0 out of 10, Exceptional, (9 reviews)
"Great property and clean. Easy move in and out. We would recommend this rental for others staying in the area."
United States
Robert F.
The price is CA $131
CA $287 total
includes taxes & fees
Sep 11 - Sep 12
The Drift at Port Royal on Battery Creek

5. Charming Coastal Casa on Beaufort's Battery Creek

Charming Coastal Casa on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (52 reviews)
"The view was worth it, peaceful"
United States
Amanda
The price is CA $131
CA $287 total
includes taxes & fees
Sep 13 - Sep 14
Charming Coastal Casa on Beaufort's Battery Creek

6. Steps to Pool & Beach: St. Helena Island Escape!

Steps to Pool & Beach: St. Helena Island Escape!
Saint Helena Island
9.8 out of 10, Exceptional, (63 reviews)
"The property is beautiful. Steps to the pool and an easy walk to the beach."
United States
Debbie’s C.
The price is CA $86
CA $499 total
includes taxes & fees
Sep 13 - Sep 14
Steps to Pool & Beach: St. Helena Island Escape!

7. Mariners' Nautical Nest on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (45 reviews)
"Perfect location "
United States
Jayda M.
The price is CA $139
CA $297 total
includes taxes & fees
Sep 14 - Sep 15
Mariners' Nautical Nest on Port Royal's Battery Creek

8. Harbor Island Beach Retreat - Steps to Ocean!

Harbor Island Beach Retreat - Steps to Ocean!
Saint Helena Island
9.8 out of 10, Exceptional, (57 reviews)
"The host was very accomodating. The condo was lovely. The access to the beach and surrounding sights was great"
United States
Michelle R.
The price is CA $116
CA $541 total
includes taxes & fees
Sep 11 - Sep 12
Harbor Island Beach Retreat - Steps to Ocean!

9. King Bed | Non-Smoking

King Bed | Non-Smoking
Ridgeland SC
10.0 out of 10, Exceptional, (237 reviews)
"Offers good value given all that comes with your stay here."
United States
Anonymous traveller
The price is CA $93
CA $110 total
includes taxes & fees
Sep 11 - Sep 12
King Bed | Non-Smoking

10. Lazy Dog Acres

Lazy Dog Acres
Ehrhardt
10.0 out of 10, Exceptional, (41 reviews)
"A great stay! I thought Issac the sweet pup was the star of the trip but husband voted for the homemade warm breakfast muffin, "
United States
Ann
The price is CA $103
CA $143 total
includes taxes & fees
Oct 1 - Oct 2
Lazy Dog Acres

11. All Inn on Edisto - Cozy Studio Condo Close to Everything

All Inn on Edisto - Cozy Studio Condo Close to Everything
Edisto Beach
9.8 out of 10, Exceptional, (185 reviews)
"Great location, nice setting, clean, and has everything needed for either a short or extended stay. "
United States
Randy B.
The price is CA $161
CA $301 total
includes taxes & fees
Sep 15 - Sep 16
All Inn on Edisto - Cozy Studio Condo Close to Everything

12. 3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL

3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL
Historic District
9.8 out of 10, Exceptional, (104 reviews)
"Enjoyed our stay. Cute and comfortable. Wish we were able to take better advantage of the big back yard. A pleasant walk to the downtown area."
United States
Richard S.
The price is CA $205
CA $488 total
includes taxes & fees
Sep 23 - Sep 24
3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL

13. Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Tranquility by the Beach 1st Fl Sleeps 6,King Bed
Mid Island
9.2 out of 10, Wonderful, (68 reviews)
"We really enjoyed our stay! The pool was great, and we especially loved the easy access to the less crowded beach!"
United States
Abigail H.
The price is CA $136
CA $397 total
includes taxes & fees
Sep 14 - Sep 15
Tranquility by the Beach 1st Fl Sleeps 6,King Bed

14. Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue

Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue
WALTERBORO
10.0 out of 10, Exceptional, (22 reviews)
"Clean room great location, beautiful stay!"
United States
Morgan K.
The price is CA $274
CA $375 total
includes taxes & fees
Sep 14 - Sep 15
Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue

15. St Helena Island Condo - 1/2 Mi to Beach

St Helena Island Condo - 1/2 Mi to Beach
Beachwalk
10.0 out of 10, Exceptional, (89 reviews)
"As advertised. Very clean, great view of the ocean and easy access to the beach. Part of a gated community but was easy to get in and out of. The community is very beautiful. Advertised as pet friendly and it was - the owners even had dog bowls and a blanket to put on the couch for the dog. Would stay here again in a heart beat!"
United States
Dale B.
The price is CA $146
CA $510 total
includes taxes & fees
Sep 23 - Sep 24
St Helena Island Condo - 1/2 Mi to Beach

16. Oceanfront St Helena Island Condo w/ Beach Access!

Oceanfront St Helena Island Condo w/ Beach Access!
Saint Helena Island
9.8 out of 10, Exceptional, (82 reviews)
"Very peaceful, clean, and sade."
United States
Richard P.
The price is CA $152
CA $608 total
includes taxes & fees
Sep 26 - Sep 27
Oceanfront St Helena Island Condo w/ Beach Access!

17. Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue

Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue
Walterboro
9.8 out of 10, Exceptional, (19 reviews)
"The cottage was perfect for our out of town guests for the wedding."
United States
Becky B.
The price is CA $274
CA $375 total
includes taxes & fees
Sep 14 - Sep 15
Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue

18. Relax & Regroup at the Beach- Let's think about Fall. Check us out!

Relax & Regroup at the Beach- Let's think about Fall. Check us out!
Fripp Island
9.8 out of 10, Exceptional, (112 reviews)
"Perfect spot for a quiet getaway. We loved our stay!"
United States
Jennifer M.
The price is CA $279
CA $698 total
includes taxes & fees
Sep 11 - Sep 12
Relax & Regroup at the Beach- Let's think about Fall. Check us out!

19. A Room With a View-1 BR Efficiency Condo Close to Everything.

A Room With a View-1 BR Efficiency Condo Close to Everything.
Edisto Beach
9.6 out of 10, Exceptional, (153 reviews)
"As advertised Cute little room with a view. Close to beaches and local restaurants. Super secluded and safe!!"
United States
Blake
The price is CA $143
CA $279 total
includes taxes & fees
Sep 13 - Sep 14
A Room With a View-1 BR Efficiency Condo Close to Everything.

20. Modern Edisto Beach Cottage - Near Golf & Resort - INCLUDES AMENITIES - Sleeps 4

Modern Edisto Beach Cottage - Near Golf & Resort - INCLUDES AMENITIES - Sleeps 4
Edisto Beach
9.6 out of 10, Exceptional, (12 reviews)
"Great place everything was clean, comfortable and a perfect size for a weekend getaway."
United States
Iboga S.
The price is CA $132
CA $431 total
includes taxes & fees
Sep 28 - Sep 29
Modern Edisto Beach Cottage - Near Golf & Resort - INCLUDES AMENITIES - Sleeps 4
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top South Carolina Lowcountry Hotel Reviews

Find out more about South Carolina Lowcountry

Everything you need to know about South Carolina Lowcountry vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the South Carolina Lowcountry vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect South Carolina Lowcountry vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

South Carolina Lowcountry vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in South Carolina Lowcountry. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A South Carolina Lowcountry vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of South Carolina Lowcountry vacation rentals we have selected for you start as low as CA $286 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on South Carolina Lowcountry rentals

At Expedia, we put the best South Carolina Lowcountry vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top South Carolina Lowcountry rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream South Carolina Lowcountry vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around South Carolina Lowcountry. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Explore a world of travel with Expedia