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South Carolina Lowcountry Vacation Rentals

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Our top choices for South Carolina Lowcountry vacation rentals

1. Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Amazing Airstream, Beaufort, SC-Enjoy the Journey!
Beaufort
9.4 out of 10, Exceptional, (29 reviews)
"Such a quaint, eclectic Airstream! Loved the decor. It was such a neat place to stay. We were visiting Paris Island because my son will be in basic soon. We hope to stay here again soon! Corner was such a great host. All of his recommendations for food and attractions were on point. Perfect visit."
United States
hunter j.
The price is CA $125
CA $245 total
includes taxes & fees
Sep 20 - Sep 21
Amazing Airstream, Beaufort, SC-Enjoy the Journey!

2. The Grey Pearl on Port Royal's Battery Creek

The Grey Pearl on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (38 reviews)
"Great property "
United States
Caleb C.
The price is CA $127
CA $278 total
includes taxes & fees
Sep 20 - Sep 21
The Grey Pearl on Port Royal's Battery Creek

3. Charming Coastal Casa on Beaufort's Battery Creek

Charming Coastal Casa on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (52 reviews)
"The view was worth it, peaceful"
United States
Amanda
The price is CA $151
CA $294 total
includes taxes & fees
Sep 25 - Sep 26
Charming Coastal Casa on Beaufort's Battery Creek

4. Mariners' Nautical Nest on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (46 reviews)
"Perfect location "
United States
Jayda M.
The price is CA $133
CA $289 total
includes taxes & fees
Sep 23 - Sep 24
Mariners' Nautical Nest on Port Royal's Battery Creek

5. Gorgeous Waterfront Battery Creek Retreat

Gorgeous Waterfront Battery Creek Retreat
Beaufort
10.0 out of 10, Exceptional, (121 reviews)
"The location was lovely and made for the perfect getaway. "
United States
Jim S.
The price is CA $133
CA $289 total
includes taxes & fees
Sep 24 - Sep 25
Gorgeous Waterfront Battery Creek Retreat

6. The Drift at Port Royal on Battery Creek

The Drift at Port Royal on Battery Creek
Beaufort
10.0 out of 10, Exceptional, (10 reviews)
"Great property and clean. Easy move in and out. We would recommend this rental for others staying in the area."
United States
Robert F.
The price is CA $133
CA $289 total
includes taxes & fees
Sep 23 - Sep 24
The Drift at Port Royal on Battery Creek

7. New Downtown 2bd w. Modern Southern Charm

New Downtown 2bd w. Modern Southern Charm
Historic District
10.0 out of 10, Exceptional, (27 reviews)
"Great location, very comfortable, easy parking, and easy walk to Bay St. shops and restaurants."
United States
Tim
New Downtown 2bd w. Modern Southern Charm

8. Harbor Island Beach Retreat - Steps to Ocean!

Harbor Island Beach Retreat - Steps to Ocean!
Saint Helena Island
9.8 out of 10, Exceptional, (57 reviews)
"The host was very accomodating. The condo was lovely. The access to the beach and surrounding sights was great"
United States
Michelle R.
The price is CA $117
CA $549 total
includes taxes & fees
Sep 23 - Sep 24
Harbor Island Beach Retreat - Steps to Ocean!

9. Lazy Dog Acres

Lazy Dog Acres
Ehrhardt
10.0 out of 10, Exceptional, (41 reviews)
"A great stay! I thought Issac the sweet pup was the star of the trip but husband voted for the homemade warm breakfast muffin, "
United States
Ann
The price is CA $94
CA $133 total
includes taxes & fees
Oct 1 - Oct 2
Lazy Dog Acres

10. King Bed | Non-Smoking

King Bed | Non-Smoking
Ridgeland SC
10.0 out of 10, Exceptional, (237 reviews)
"Good location, easy access to restaurants nearby."
United States
Anonymous traveller
The price is CA $123
CA $144 total
includes taxes & fees
Sep 21 - Sep 22
King Bed | Non-Smoking

11. St Helena Island Condo - 1/2 Mi to Beach

St Helena Island Condo - 1/2 Mi to Beach
Beachwalk
10.0 out of 10, Exceptional, (91 reviews)
"As advertised. Very clean, great view of the ocean and easy access to the beach. Part of a gated community but was easy to get in and out of. The community is very beautiful. Advertised as pet friendly and it was - the owners even had dog bowls and a blanket to put on the couch for the dog. Would stay here again in a heart beat!"
United States
Dale B.
The price is CA $148
CA $522 total
includes taxes & fees
Sep 23 - Sep 24
St Helena Island Condo - 1/2 Mi to Beach

12. Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue

Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue
Walterboro
9.8 out of 10, Exceptional, (19 reviews)
"The cottage was perfect for our out of town guests for the wedding."
United States
Becky B.
The price is CA $278
CA $381 total
includes taxes & fees
Sep 21 - Sep 22
Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue

13. Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue

Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue
WALTERBORO
10.0 out of 10, Exceptional, (22 reviews)
"Clean room great location, beautiful stay!"
United States
Morgan K.
The price is CA $278
CA $381 total
includes taxes & fees
Sep 21 - Sep 22
Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue

14. All Inn on Edisto - Cozy Studio Condo Close to Everything

All Inn on Edisto - Cozy Studio Condo Close to Everything
Edisto Beach
9.8 out of 10, Exceptional, (186 reviews)
"Great location, nice setting, clean, and has everything needed for either a short or extended stay. "
United States
Randy B.
The price is CA $138
CA $274 total
includes taxes & fees
Sep 21 - Sep 22
All Inn on Edisto - Cozy Studio Condo Close to Everything

15. 3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL

3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL
Historic District
9.8 out of 10, Exceptional, (104 reviews)
"Enjoyed our stay. Cute and comfortable. Wish we were able to take better advantage of the big back yard. A pleasant walk to the downtown area."
United States
Richard S.
The price is CA $231
CA $526 total
includes taxes & fees
Oct 4 - Oct 5
3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL

16. Frippin Fun Vacation - Fripp Island

Frippin Fun Vacation - Fripp Island
Saint Helena Island
9.0 out of 10, Wonderful, (47 reviews)
"Perfect one bedroom condo and in a great location.."
United States
Wendie C.
The price is CA $138
CA $403 total
includes taxes & fees
Sep 22 - Sep 23
Frippin Fun Vacation - Fripp Island

17. Luxury Penthouse near Beach, Tiki Hut, Coligny

Luxury Penthouse near Beach, Tiki Hut, Coligny
South End
10.0 out of 10, Exceptional, (119 reviews)
"Had a great stay. Definitely recommend."
United States
Thomas K.
The price is CA $21
CA $527 total
includes taxes & fees
Sep 23 - Sep 24
Luxury Penthouse near Beach, Tiki Hut, Coligny

18. Modern Edisto Beach Cottage - Near Golf & Resort - INCLUDES AMENITIES - Sleeps 4

Modern Edisto Beach Cottage - Near Golf & Resort - INCLUDES AMENITIES - Sleeps 4
Edisto Beach
9.6 out of 10, Exceptional, (12 reviews)
"Great place everything was clean, comfortable and a perfect size for a weekend getaway."
United States
Iboga S.
The price is CA $136
CA $437 total
includes taxes & fees
Sep 23 - Sep 24
Modern Edisto Beach Cottage - Near Golf & Resort - INCLUDES AMENITIES - Sleeps 4

19. Cozy Edisto Condo-Close to the Beach!

Cozy Edisto Condo-Close to the Beach!
Edisto Beach
9.0 out of 10, Wonderful, (119 reviews)
"Great place"
United States
Annah B.
The price is CA $132
CA $266 total
includes taxes & fees
Sep 21 - Sep 22
Cozy Edisto Condo-Close to the Beach!

20. C & N Lodging, Bluffton, SC

C & N Lodging, Bluffton, SC
Bluffton
9.8 out of 10, Exceptional, (11 reviews)
"Great place to stay. Charming decor, comfortable bed. Great communication with host. "
United States
Erika H.
The price is CA $176
CA $325 total
includes taxes & fees
Sep 21 - Sep 22
C & N Lodging, Bluffton, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Lowcountry Hotel Reviews

Find out more about South Carolina Lowcountry

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with South Carolina Lowcountry. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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