
Wise Vacation Packages
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Save up to CA $1,096 when you book a flight and hotel together*
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Your Wise Vacation
Lock in a Wise vacation package and get set for an awesome adventure. With a reputation for its friendly locals and rural countryside, there's tons to like about this interesting city. A trip to Wise is a wonderful opportunity to do some sightseeing. Check out big-name attractions such as University of Virginias College at Wise, High Knob and Big Glades Community Square & Amphitheater. Stop daydreaming and start traveling. Check out the many options on Expedia today and put your Wise vacation plans in motion!
Wise Hotel Deals

The Inn at Wise
110 E Main Street, Wise, VA
Fully refundableReserve now, pay when you stay
The price is CA $164 per night from Aug 17 to Aug 18
CA $164
CA $182 total
Aug 17 - Aug 18
includes taxes & fees
9.2/10 Wonderful! (987 reviews)
"I was so happy to see the Inn restored to a useful Condition! Enjoyed immensely my 2day stay with the Quiet atmosphere and beauty of this building. Food was great and good selection. Hospitality was very Much a part of making my stay so enjoyable. It’s a Good start and will grow larger and ..."
Reviewed on Aug. 6, 2025

Best Western Of Wise
124 Woodland Drive SW, Wise, VA
Fully refundableReserve now, pay when you stay
The price is CA $134 per night from Aug 12 to Aug 13
CA $134
CA $150 total
Aug 12 - Aug 13
includes taxes & fees
7.8/10 Good! (479 reviews)
"Liked everything"
Reviewed on Jul. 15, 2025

Nottingham Turret Rm w Queen Bed, Near UVaWise & Main St, Private Detached Bath
Wise
The price is CA $161 per night from Aug 17 to Aug 18
CA $161
CA $210 total
Aug 17 - Aug 18
includes taxes & fees
10/10 Exceptional! (11 reviews)
Beautiful place!
"I enjoy this beautiful historic house when I’m in Wise!"
Reviewed on Jul. 9, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.