Texas Medical Center Vacation Packages

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Top Holiday Package Deals in Texas Medical Center

Price found within the past 48 hours. Click for updated prices.
Hyatt Place Houston/Galleria

Hyatt Place Houston/Galleria

3 out of 5
Greater Uptown
per person
Oct 13 - Oct 18
found 3 hours ago
Roundtrip flight included
Calgary (YYC) to Houston (IAH)
8.8/10 Excellent! (1,006 reviews)
Everything was great only a couple call outs Elevator speed (takes forever it’s only 10 floors) Breakfast selection Pool size Everything else great !!

Reviewed on Jul. 29, 2025

Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria

4 out of 5
The Galleria
per person
Oct 13 - Oct 18
found 3 hours ago
Roundtrip flight included
Calgary (YYC) to Houston (IAH)
8.8/10 Excellent! (1,001 reviews)
Great place to stay at for a short trip, lovely

Reviewed on Jul. 29, 2025

The Lancaster Hotel

The Lancaster Hotel

4 out of 5
Downtown Houston
per person
Sep 25 - Sep 28
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Houston (IAH)
9.6/10 Exceptional! (1,005 reviews)
Luxury, Impeccable service, friendly, quality amenities, great food, clean, quiet.

Reviewed on Jul. 29, 2025

La Colombe d'Or Hotel

La Colombe d'Or Hotel

5 out of 5
Montrose
per person
Sep 25 - Sep 28
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Houston (IAH)
9.2/10 Wonderful! (120 reviews)
Beautiful hotel with great pool, bar and restaurant. Helpful staff and spacious rooms. Quaint and lovely.

Reviewed on Jul. 26, 2025

Blossom Hotel Houston

Blossom Hotel Houston

4 out of 5
Texas Medical Center
per person
Oct 13 - Oct 18
found 3 hours ago
Roundtrip flight included
Calgary (YYC) to Houston (IAH)
9.2/10 Wonderful! (3,391 reviews)
Very nice hotel. Staff was amazing at check-in. Room was surprisingly spacious. Great place to stay if you are vistingbthe medical center area.

Reviewed on Jul. 30, 2025

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Discovery Green which includes city views, a square or plaza and a skyscraper

Downtown Houston

3 out of top 10 points of interest in this area
4/5(79 area reviews)

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Find hotels in Downtown Houston

Texas Medical Center Hotel Deals

Blossom Hotel Houston

Blossom Hotel Houston

4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
The price is CA $175 per night from Aug 28 to Aug 29
CA $175
CA $205 total
Aug 28 - Aug 29
includes taxes & fees
9/10 Wonderful! (3,431 reviews)
"this place is absolutely beautiful i will definitely be back"

Reviewed on Jul. 27, 2025

Blossom Hotel Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
The price is CA $126 per night from Aug 10 to Aug 11
CA $126
CA $149 total
Aug 10 - Aug 11
includes taxes & fees
8.2/10 Very Good! (1,487 reviews)
"Convenient to medical district"

Reviewed on Jul. 28, 2025

Hilton Houston Plaza/Medical Center
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
The price is CA $153 per night from Aug 5 to Aug 6
CA $153
CA $180 total
Aug 5 - Aug 6
includes taxes & fees
9/10 Wonderful! (1,838 reviews)
"I just didn’t realize the amount of kids i should’ve done more research it was like a summer program or something going on. But the staff was very helpful"

Reviewed on Jul. 28, 2025

Hyatt Place Houston Medical Center
See all 6,497 properties in Texas Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Texas Medical Center vacation package cost?
Much less than you might think — from only CA $781, in fact! By bundling flights, hotels and car rentals into a tailor-made vacation package, your getaway to Texas Medical Center is just a few clicks away.
How do I get a cheap travel package to Texas Medical Center?
Browse and lock in everything in the one place with our Texas Medical Center vacation packages. You'll discover bargains on flights, hotels, tours and more that'll keep your hip pocket happy and your adventurous spirit alive. And, with more than 550 airlines and 1,000,000 properties all over the world to select from, you'll have the flexibility to mix and match as you please.
Where should I stay in Texas Medical Center?
Choose a place close to Houston Zoo. This famous sight is in the middle of the action and on the must-see lists of many travelers.
What are the top hotels in Texas Medical Center?
Hilton Garden Inn Houston Medical Center, TX and Home2 Suites by Hilton Houston Medical Center, TX are two of the most well-known hotels in Texas Medical Center. Why not have a look at the rates and amenities at each and then decide?
How far in advance should I book my Texas Medical Center vacation?
Browse Expedia to compare international flights as soon as you know your travel dates. You can normally purchase a ticket up to a year in advance. If it's too early for your preferred air carrier, or you have to book last minute, don't stress. Low prices to Texas Medical Center occasionally appear just weeks before the date of departure.
What does an Expedia Texas Medical Center travel package include?
Expedia has all you need to lock in Texas Medical Center trip, but how your package is structured is your choice. Choose from a combination of rental cars, flights and hotels. In search of a few activities to keep you busy? Once you've made your booking, you can add them too. Whatever your style or budget, there's a package deal to match your needs.
What should I know before booking a Texas Medical Center travel package?
Our prices are already low. However, you'll snap up even more savings when you book your flights, hotels and car rentals together. With an Expedia travel package, you'll get transparent pricing and a terrific range of choice.
Can I choose my airline with a Texas Medical Center Expedia vacation package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines around the world. Our packages give you the flexibility to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Texas Medical Center vacation package?
It's difficult to predict what tomorrow might bring, so it's good to know that you can change or cancel your Texas Medical Center vacation package. If you made your booking in the last 24 hours, you may be eligible for a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to learn more.

Discover the most popular places to visit in Texas Medical Center

MD Anderson Cancer Center

Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.

MD Anderson Cancer Center

Things to do

Houston Museum of Natural Sciences: Planetarium Ticket

Houston Museum of Natural Sciences: Planetarium Ticket

CA $16
per adult
80% of travellers recommend
Houston Museum of Natural Sciences: Planetarium Ticket
Houston: Downtown Aquarium All Day Pass

Houston: Downtown Aquarium All Day Pass

CA $37
per adult
Houston: Downtown Aquarium All Day Pass
Houston: Houston Botanic Garden Entry Ticket

Houston: Houston Botanic Garden Entry Ticket

CA $16
per adult
Houston: Houston Botanic Garden Entry Ticket
See all activities in Houston
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.