Hotels by La Quinta Inn & Suites in St. Louis from CA $104

A large white building with a dome and a statue in front, surrounded by fountains and trees.

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Our top choices for St. Louis La Quinta Inn & Suites

A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

A modern hotel lobby with a cityscape view, a reception desk, and ambient lighting.

A modern dining area with multiple tables and chairs, large windows offering a view of the outdoors, and a mix of natural and artificial lighting.

A modern hotel lobby with a seating area, a desk, and large windows offering a view of the outside.

1. La Quinta Inn & Suites by Wyndham St Louis Route 66

St. Louis

Crystal

CA $150

CA $175 total

includes taxes & fees

Oct 4 - Oct 5

A hotel with a covered entrance, a tower with signage, and a landscaped area with planters.

A covered outdoor seating area with a pergola, surrounded by landscaped bushes and a paved walkway.

A hotel room with purple walls, a flat-screen TV, a bed, a dining table with chairs, a sofa, and a window with curtains.

A hotel room with two beds, a desk, a TV, and a window with curtains.

2. La Quinta Inn & Suites by Wyndham St. Louis Westport

Westport

Gary

CA $114

CA $133 total

includes taxes & fees

Oct 25 - Oct 26

A reception area with a cityscape mural, a snack bar, and a refrigerator.

A breakfast bar with a toaster, coffee maker, and a refrigerator stocked with beverages and pastries.

A hotel room with a large bed, a sofa, a desk, and a window with curtains.

A kitchen with wooden cabinets, a refrigerator, and shelves stocked with snacks and beverages.

3. La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Hazelwood

Troy

CA $85

CA $104 total

includes taxes & fees

Oct 4 - Oct 5

A lobby with a blue sofa, patterned cushions, a reception desk, and a mural of a moon and arch.

A hotel with a central entrance, multiple floors, and a clear sky.

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

A breakfast bar with a microwave, coffee makers, and a fruit display.

4. La Quinta Inn & Suites by Wyndham Pontoon Beach

Granite City

Weldon

CA $154

CA $177 total

includes taxes & fees

Sep 29 - Sep 30

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Top St. Louis Hotel Reviews

Hyatt Regency St. Louis at The Arch

10/10 Excellent

"Amazing stay. I would book again!"

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Everyone was very pleasant to work with. Everyone was very knowledgeable and helpful. Will use again"

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"The only thing I wasn't happy about was that I called the day before to inquire about early check in and was told you call a few hours before check in to see if it was possible. I called about 5 hours before check in and was told it was on a first come first serve basis starting at 1 pm. I got there exactly at 1 only to be told no rooms were available. Such an inconvenience. I feel as though there could be a lot more transparency or straightforwardness in this aspect. Outside of that, great hotel and enjoyed the stay with its amenities"

21C Museum Hotel St Louis

10/10 Excellent

"Such a cool and trendy boutique hotel with all the amenities. Beautiful building. Paid parking around d the corner. 20 minutes walk to the Gateway Arch. So nice to get back to the hotel in the evening, have a few drinks at the bar and finish the evening with a visit to the pool area with hot tub, sauna, and steam room as well as the lap pool. Staff were incredible, so friendly and knowledgeable. Kristos and all the other bartenders were super friendly and made us some great cocktails. Would definitely recommend to friends and family and would stay again if we were back in the area."

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"I wish that the Pear Inn Hotel provided shuttle service to their guests."

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"We loved our stay. Everything was clean and the bed was the most comfortable hotel bed I’ve slept on. We had a blast. The breakfast was delicious."

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent

"Our room was very nice. The room and bathroom were spacious and bed was very comfortable. Hospitality was superb! Highly recommend."

Courtyard by Marriott St. Louis Downtown/Convention Center

10/10 Excellent

"The place was great!!!!!!!"

Tru By Hilton St. Louis Downtown

10/10 Excellent

"Although they had a very busy weekend, they made sure to accommodate our needs and were very patient and understanding. I would stay here again if I visit the Midwest again."

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Find Hotels by La Quinta Inn & Suites in St. Louis from CA $104

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for St. Louis La Quinta Inn & Suites

1. La Quinta Inn & Suites by Wyndham St Louis Route 66

2. La Quinta Inn & Suites by Wyndham St. Louis Westport

3. La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

4. La Quinta Inn & Suites by Wyndham Pontoon Beach

Top St. Louis Hotel Reviews

Hyatt Regency St. Louis at The Arch

Pear Tree Inn St. Louis Airport

Drury Plaza Hotel St. Louis Union Station

21C Museum Hotel St Louis

Pear Tree Inn St. Louis Near Union Station

Clayton Plaza Hotel & Extended Stay

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Courtyard by Marriott St. Louis Downtown/Convention Center

Tru By Hilton St. Louis Downtown

Explore a world of travel with Expedia