Southern Illinois Vacation Packages
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Your Southern Illinois Vacation
When adventure is calling, answer it with a vacation package to Southern Illinois. Well known for its culture and history, this is one destination you'll never forget. Start your trip to Southern Illinois with a few nights in O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that draws travellers from far and wide. Lake Sara and Effingham Performance Centre are two of the leading places to see in this destination. Quit dreaming and get packing, because your Southern Illinois vacation is just clicks away with Expedia.
Top Southern Illinois Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Remodeled and Inviting Free EV
CA $1,164
per person
Nov 16 - Nov 19
found 24 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
9/10 Wonderful! (2 reviews)
It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it
Reviewed on Aug 7, 2026
Where to stay in Southern Illinois
Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
Eastport
If you're spending some time in Eastport, Splash City Family Waterpark and Gateway Conference Center are top sights worth seeing.
Uptown
If you're spending some time in Uptown, Kruta Bakery and World's Largest Catsup Bottle are top sights worth seeing.
Mulberry Hills
While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.
Alorton
Alorton is well-liked for its restaurants. If you'd like to do some sightseeing in the greater East St. Louis area, you might plan a trip to Frank Holten State Recreation Area or Arsenal BG Ballpark.
Historic Downtown Collinsville
While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.
Ready to book your vacation to Southern Illinois?
Southern Illinois Hotel Deals
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
CA $128
CA $145 total
Nov 1 - Nov 2
includes taxes & fees
9.2/10 Wonderful! (1,042 reviews)
"Lovely 3 night stay. Was greeted with a warm welcome, invited for happy hour and a dinner if we did not eat yet! Suite was clean, pool and hot tub area were clean as well. If in area again we will definitely book here!!!"
Reviewed on Oct 9, 2026
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
CA $158
CA $178 total
Oct 18 - Oct 19
includes taxes & fees
9.8/10 Exceptional! (1,831 reviews)
"This was the best hotel I’ve stayed in. The accommodations were outstanding with wonderful people managing the desk! Two young ladies helped us and it was amazing!"
Reviewed on Oct 9, 2026
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
CA $145
CA $168 total
Oct 19 - Oct 20
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Southern Illinois attractions
Garden of the Gods Recreation Area
9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
St. Claire Square Mall
8.4/10 (133 reviews)
You can browse for the perfect souvenirs at St. Claire Square Mall during your visit to Fairview Heights. Discover the top-notch restaurants and great live music in this family-friendly area.
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
Frequently asked questions
How much does a Southern Illinois vacation package cost?
From just CA $728, you can tailor make your Southern Illinois vacation package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Southern Illinois?
Bundle your flights and hotels with Expedia to save big on your next big adventure. With over 550 airlines and 1,000,000 hotels globally, your Southern Illinois vacation package can be tailored exactly to suit your budget. With all that extra money, why not throw in one or more awesome activities and tours? It's an easy way to unlock even more discounts. Your dream getaway to Southern Illinois is much closer than you thought!
What are the top hotels in Southern Illinois?
Take a look at Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for lots of travelers to Carbondale. If Marion is on your travel itinerary, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of popular options.
How far in advance should I book my Southern Illinois vacation?
Reward yourself with the widest variety at the lowest prices by booking your vacation to Southern Illinois early. Air carriers usually sell flight tickets around 12 months before departure, so reserve your spot ASAP. That said, Expedia is dedicated to giving you the best bargains around, so it's never a bad time to book your dream vacation!
What does an Expedia Southern Illinois travel package include?
That depends on what sort of trip you're contemplating. Southern Illinois vacation deals can include flights, hotels and car rentals. You can mix and match to create the travel package that suits you. You can also add on experiences and activities after you've booked to get even bigger discounts.
What should I know before booking a Southern Illinois travel package?
You'll score excellent savings when you combine your flights, hotels and rental cars into a package. Not only that, booking everything in one spot will make your trip planning easier. So why waste your money or time? Whether you're organizing a ritzy city getaway or a low-cost family road trip, explore our vacation packages today.
Can I choose my airline with a Southern Illinois Expedia vacation package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Browse the available options and see which airline fits your needs and budget.
If I'm not able to travel, can I cancel my Southern Illinois vacation package?
You can cancel your Southern Illinois booking if your plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
Explore a world of travel with Expedia
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- Adults Only Resorts & in Southern Illinois
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- Super 8 by Wyndham Du Quoin
- Drury Inn & Suites Marion
- B&B in Du Quoin
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- Villas in Galatia
- Cabin Rentals in Salem
- Hotels with Balconies in Marion
- Best location on Lake of Egypt by land and by water!
- Cabin Rentals in Omaha
- Mount Erie Hotels
- Modern Pond
- 3 Star Hotels in Royalton
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- Holiday Inn Express & Suites Mount Vernon by IHG
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- America's Best Inns Hotels in Waltonville
- Resorts in Harrisburg
- Farmstay in Dowell
- Cottages in Zeigler
- Eldorado Hotels
- Super 8 by Wyndham Salem
- Belle Prairie City Hotels
- Farmstay in Sunfield
- Hotels with smoking rooms in Marion
- Carmi Hotels
- Hotels with Hot Tubs in Carlyle
- Mcleansboro Hotels
- Hotels with an Indoor Pool in Harrisburg
- Keenes Hotels
- Rv Parks in Cutler
- Thompsonville Hotels
- Villas in Benton
- Apartments in Cisne
- Harrisburg Hotels
- Quality Inn & Suites Marion
- Villas in Buckner
- 3 Star Hotels in Keenes
- Cabin Rentals in Carlyle
- Best Western Plus Centralia Hotel & Suites
- Mount Vernon Hotels
- Treehouse w/ Hot Tub near Shawnee National Forest
- Apartments in Fairfield
- Flights from Toronto (YYZ) to Carbondale (MDH)
- Flights from Vancouver (YVR) to Mount Vernon (MVN)
- Flights to Ina
- Flights from Benton
- Flights to Fairfield
- Flights from Waltonville
- Flights from Carterville
- Flights from Mount Vernon
- Flights from Belle Rive
- Flights to Marion
- Flights to Centralia
- Flights to Southern Illinois
- Flights from Cutler
- Flights from Cisne
- Flights from Macedonia
- Flights to Benton
- Flights from Elkville
- Flights from Christopher
- Flights from Phoenix (PHX) to Carbondale (MDH)
- Flights to Du Quoin
- Flights from Cleveland (CLE) to Carbondale (MDH)
- Flights to Patoka
- Flights to Mount Vernon
- Flights to Flora
- Flights from Ewing
- Flights from Columbus (CMH) to Carbondale (MDH)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
