Title: Book the Best Southern Illinois SPA Resorts from CA $92 - Spa Hotels in Southern Illinois, IL | Expedia.ca [Southern Illinois Travel Guide](https://expedia.ca/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.ca/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Vacation Rentals in Southern Illinois](https://expedia.ca/Southern-Illinois-Vacation-Rentals.d6233859.Travel-Guide-VacationRentals)[Flights to Southern Illinois](https://expedia.ca/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Illinois.d6233859.Car-Rental-Guide)[Southern Illinois Vacation Packages](https://expedia.ca/Southern-Illinois.d6233859.Destination-Travel-Guides) ![Fort Massac State Park showing a statue or sculpture, a lake or waterhole and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208712-Southern-Illinois.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Southern Illinois, IL from CA $92 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Illinois Spa Hotels Tonight [Sep 23 - Sep 24](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-09-23&endDate=2025-09-24&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-09-24&endDate=2025-09-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-09-26&endDate=2025-09-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southern Illinois Spa Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/b6b6aa46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/a5bed563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/bd52110c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Mt. Vernon Mount Vernon 9.6/10 Exceptional (1466) "Loved our stay" CA $131 CA $148 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Non Smoking](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/bea2db9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/4df2fec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/43f13195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Mount Vernon Mount Vernon 8.8/10 Excellent (1023) "Our stay was very good. " CA $172 CA $193 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1720000/1710800/1710768/eb3ef88a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/2000000/1720000/1710800/1710768/af31ff58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1720000/1710800/1710768/2b4f4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1720000/1710800/1710768/faff3ffc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Marriott Effingham Effingham 9.0/10 Wonderful (472) "Nice, quality hotel" CA $133 CA $147 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Effingham-Hotels-Fairfield-Inn-Suites-Marriott-Effingham.h1710768.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Larger Room)](https://images.trvl-media.com/lodging/3000000/2670000/2662200/2662110/ed2d0598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2670000/2662200/2662110/ec191b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/3000000/2670000/2662200/2662110/ce62cabd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/3000000/2670000/2662200/2662110/6e8d1c28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus MidAmerica Hotel Mascoutah 9.0/10 Wonderful (1006) "Staff was very helpful..military discount.. Clean rooms and breakfast lounge.." CA $155 CA $172 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Collinsville-Hotels-Best-Western-Plus-MidAmerica-Hotel.h2662110.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/08714d2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/98936ea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/63665e0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/c64614a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Effingham North Effingham 8.4/10 Very good (955) "Clean nice hotel" CA $123 CA $136 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Effingham-Hotels-Quality-Inn-Effingham.h82513.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/100000/99000/98915/e697fbb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels](https://images.trvl-media.com/lodging/1000000/100000/99000/98915/1a7f3449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/100000/99000/98915/594403fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/100000/99000/98915/15cad0bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Metropolis, IL Metropolis 7.2/10 Good (525) "Good people " CA $83 CA $92 total includes taxes & fees Sep 24 - Sep 25 [](https://www.expedia.ca/Metropolis-Hotels-Motel-6-Metropolis.h98915.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/6cba26b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/8e4b3d15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/140c98cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/25e2a26d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Effingham Effingham 9.2/10 Wonderful (1009) "Loved the quietness during our stay. " CA $134 CA $150 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Effingham-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Effingham.h50093.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/910000/904900/904826/edc9d870.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904900/904826/9c7ac0a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/904900/904826/1b7c58f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/910000/904900/904826/f51b759a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Fairview Heights - St. Louis Fairview Heights 7.4/10 Good (506) "The rooms are nice, the breakfast is really good and the staff are friendly and helpful." CA $111 CA $125 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Fairview-Heights-Hotels-Four-Points-By-Sheraton-St-Louis-Fairview-Heights.h904826.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/7000000/6600000/6594500/6594436/bd13b43c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/7000000/6600000/6594500/6594436/06b2dd57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6600000/6594500/6594436/d006a943.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6600000/6594500/6594436/e3462d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Hotel & Suites - Newton Newton 9.2/10 Wonderful (316) "Clean, pet friendly, nice breakfast,nice bar area staff was helpful and friendly " CA $133 CA $148 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Effingham-Hotels-Cobblestone-Hotel-Suites-Newton.h6594436.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42035/fff178d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42100/42035/8cf4bdc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42100/42035/277e17ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42100/42035/228e608d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Collinsville Eastport 9.6/10 Exceptional (1010) "Had a great stay! Will stay again. " CA $144 CA $165 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Collinsville.h42035.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-07&endDate=2025-10-08®ionId=6233859&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Southern Illinois Hotel Reviews ![Drury Plaza Hotel Mt. Vernon](//images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Outstandingly clean facility staffed by people who almost felt like family. They took pride and where they worked and made me feel like I was coming home." [](https://expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Drury Inn & Suites St. Louis O'Fallon, IL](//images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d2bc121f_y.jpg) ### Drury Inn & Suites St. Louis O'Fallon, IL 10/10 Excellent "Drury is nicely located around the commercial area of O'Fallon. Good restaurants near the hotel. Great staff. Room is clean. I would recommend this place." [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![Comfort Suites Mount Vernon](//images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "The pool and gym are open 24 hrs, and its pet friendly!" [](https://expedia.ca/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](//images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "They need to teach the housekeeping staff to not park their carts in the middle of the hallway. This makes it really hard to navigate the hallway with luggage. " [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Best Western Plus Pontoon Beach](//images.trvl-media.com/lodging/3000000/2700000/2695400/2695352/01153352_y.jpg) ### Best Western Plus Pontoon Beach 10/10 Excellent "Everyone was nice. The staff that checked us in was a man of few words but the ladies that check us out were 10/10!! " [](https://expedia.ca/St-Louis-Hotels-Best-Western-Plus-Pontoon-Beach.h2695352.Hotel-Information) ![Country Inn & Suites by Radisson, Effingham, IL](//images.trvl-media.com/lodging/1000000/920000/914400/914400/f2163f3d_y.jpg) ### Country Inn & Suites by Radisson, Effingham, IL 10/10 Excellent "Great staff" [](https://expedia.ca/Effingham-Hotels-Country-Inn-Suites-By-Radisson.h914400.Hotel-Information) ![Quality Inn O'Fallon IL - St. Louis](//images.trvl-media.com/lodging/1000000/70000/64700/64675/8890354b_y.jpg) ### Quality Inn O'Fallon IL - St. Louis 10/10 Excellent "I have stayed here several times over the past 2 years and like it. My room is clean and the location vey convenient at a reasonable price. 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