Title: Book the Best Southeastern United States SPA Resorts - Spa Hotels in Southeastern United States | Expedia.ca [Southeastern United States Travel Guide](https://expedia.ca/Southeastern-United-States.dx6209937)[Hotels in Southeastern United States](https://expedia.ca/Southeastern-United-States-Hotels.d6209937.Travel-Guide-Hotels)[Vacation Rentals in Southeastern United States](https://expedia.ca/Southeastern-United-States-Vacation-Rentals.d6209937.Travel-Guide-VacationRentals)[Flights to Southeastern United States](https://expedia.ca/Cheap-Flights-To-Southeastern-United-States.d6209937.Travel-Guide-Flights)[Southeastern United States Car Rentals](https://expedia.ca/Car-Rentals-In-Southeastern-United-States.d6209937.Car-Rental-Guide)[Southeastern United States Vacation Packages](https://expedia.ca/Southeastern-United-States.d6209937.Destination-Travel-Guides) ![Universal Studios Orlando which includes a castle](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22555-Universal-Studios-Orlando.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Southeastern United States - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeastern United States Spa Hotels Tonight [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6209937&startDate=2025-10-31&endDate=2025-11-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6209937&startDate=2025-11-01&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6209937&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6209937&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeastern United States Spa Hotels ![10 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/14000000/13320000/13319600/13319510/10874301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/14000000/13320000/13319600/13319510/4e39a809.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/14000000/13320000/13319600/13319510/7d3a611b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/14000000/13320000/13319600/13319510/a086f6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harrah's Cherokee – A Caesars Rewards Destination Cherokee 8.6/10 Excellent (3039) "Good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy CA $387 CA $484 total includes taxes & fees Nov 8 - Nov 9 [](https://www.expedia.ca/Cherokee-Hotels-Harrahs-Cherokee-Casino-Resort.h13319510.Hotel-Information) ![Couples treatment rooms, body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/1000000/900000/891200/891178/bdd79048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/900000/891200/891178/1fbd348e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/900000/891200/891178/09c14df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/891200/891178/ab1be3a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carnegie Hotel & Spa Johnson City 9.8/10 Exceptional (1284) "Location was near plenty of places to eat. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carrie CA $270 CA $318 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Johnson-City-Hotels-Carnegie-Hotel-Spa.h891178.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1470000/1460500/1460425/f7fc38d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/2000000/1470000/1460500/1460425/2ac14176.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/2000000/1470000/1460500/1460425/eadb38ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, open 5:30 AM to midnight, cabanas (surcharge)](https://images.trvl-media.com/lodging/2000000/1470000/1460500/1460425/cca9a672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rosen Shingle Creek Orlando 9.4/10 Exceptional (4099) "Always a great experience when we stay here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marla CA $150 CA $169 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Orlando-Hotels-Rosen-Shingle-Creek.h1460425.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1490000/1489300/1489240/a90679f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1490000/1489300/1489240/f2b37206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1490000/1489300/1489240/072646b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1490000/1489300/1489240/e5ab48db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Port Canaveral, FL Cape Canaveral 9.0/10 Wonderful (2888) "Very nice hotel with a very short drive to cruise terminals." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Skyler CA $191 CA $214 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Cape-Canaveral-Hotels-Country-Inn-Suites-By-Radisson.h1489240.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/0212aa65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Ocean View | Living area](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/edac1497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/ae3152a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/w495h217x0y6-f026e9f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harborside at Charleston Harbor Resort and Marina Mount Pleasant 8.6/10 Excellent (2013) "Lovely hotel in a great location, I highly recommend it! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond CA $118 CA $199 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/Charleston-Hotels-Harborside-At-Charleston-Harbor-Resort-And-Marina.h67652.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4410000/4408100/4408039/5e3aaa71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch, dinner served; sushi](https://images.trvl-media.com/lodging/5000000/4410000/4408100/4408039/f5e4827f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake](https://images.trvl-media.com/lodging/5000000/4410000/4408100/4408039/c8099ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4410000/4408100/4408039/57f8ea14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Grand Orlando Resort Bonnet Creek Orlando 8.8/10 Excellent (2796) "Great hotel!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leeanne CA $188 CA $274 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Orlando-Hotels-Wyndham-Grand-Orlando-Resort-Bonnet-Creek.h4408039.Hotel-Information) ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/e77d9aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/79d31a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/981feca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cheeca Lodge & Spa Matecumbe 9.2/10 Wonderful (1265) "This resort was amazing!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $278 CA $407 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/e7ff60a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/364a95a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 7:30 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/b66654c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/e23881fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beau Rivage Downtown Biloxi 9.2/10 Wonderful (1410) "Nice Hotel! Staff very friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $180 CA $235 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Biloxi-Hotels-Beau-Rivage.h199634.Hotel-Information) ![Private beach, white sand, beach cabanas, sun loungers](https://images.trvl-media.com/lodging/1000000/810000/809000/808920/65d99be5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/810000/809000/808920/0bdf76db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/1000000/810000/809000/808920/3a47c465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809000/808920/b6ab9541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Sands Beach Boutique Inn - 1 Acre Private Beach Vilano Beach 8.8/10 Excellent (628) "such a beautiful Inn it has so much to do or you can do nothing we stayed on the beach view side and it was very pretty breakfast every morning was hot and fresh, super delicious " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) EDWARD CA $124 CA $138 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/St-Augustine-Hotels-Ocean-Sands-Beach-Inn.h808920.Hotel-Information) ![Deep-tissue massages, Swedish massages, body scrubs, facials](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/2c58a908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/298d55e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/bf4d999e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/6049152a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palace Casino Resort Summerville 9.2/10 Wonderful (2919) "Always an amazing stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $110 CA $123 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Biloxi-Hotels-Palace-Casino-Resort.h1652862.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15®ionId=6209937&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southeastern United States ### Top Southeastern United States attractions for a relaxing vacation In the Southeastern United States, a wealth of luxurious spa hotels awaits those seeking relaxation and rejuvenation. The serene beaches of the Florida Keys offer not only breathtaking sunsets but also an array of oceanfront spas where treatments utilise local ingredients like sea salt and coconut oil. Just a short drive away, the historic charm of Savannah, Georgia, invites guests to explore its lush, tree-lined squares before unwinding in one of its boutique hotels featuring full-service day spas. For the adventurous, the Great Smoky Mountains provide a perfect backdrop for hiking and exploration, with several lodges offering spa facilities that incorporate natural elements and views of the stunning scenery. Additionally, the vibrant city of New Orleans boasts exquisite spa hotels that combine indulgent treatments with the unique culture of the city, including jazz-infused relaxation sessions. Finally, the picturesque coastal towns of South Carolina, such as Charleston and Hilton Head, offer both rich history and tranquil spa experiences, perfect for unwinding after a day of exploring cobblestone streets or pristine beaches. With these diverse locations, each providing unique spa experiences and the opportunity for adventure, families can find the perfect blend of relaxation and excitement. ## Top Southeastern United States Hotel Reviews ![DoubleTree by Hilton at the Entrance to Universal Orlando](//images.trvl-media.com/lodging/1000000/10000/5400/5398/4997b5df_y.jpg) ### DoubleTree by Hilton at the Entrance to Universal Orlando 10/10 Excellent "Access " [](https://expedia.ca/Orlando-Hotels-DoubleTree-By-Hilton-At-The-Entrance-To-Universal-Orlando.h5398.Hotel-Information) ![Rosen Inn at Pointe Orlando](//images.trvl-media.com/lodging/1000000/10000/8900/8892/8068a653_y.jpg) ### Rosen Inn at Pointe Orlando 10/10 Excellent "Está muy linda " [](https://expedia.ca/Orlando-Hotels-Rosen-Inn-At-Pointe-Orlando.h8892.Hotel-Information) ![Holiday Inn & Suites Orlando SW - Celebration Area by IHG](//images.trvl-media.com/lodging/1000000/10000/7900/7855/e4318c5d_y.jpg) ### Holiday Inn & Suites Orlando SW - Celebration Area by IHG 10/10 Excellent "Great place." [](https://expedia.ca/Orlando-Hotels-Holiday-Inn-Orlando-SW-Celebration-Area.h7855.Hotel-Information) ![Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando](//images.trvl-media.com/lodging/1000000/30000/23200/23110/ade3b60d_y.jpg) ### Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando 10/10 Excellent "Staff was very helpful and nice. Our villa was beautiful. Loved every bit of it and will definitely stay again " [](https://expedia.ca/Orlando-Hotels-Sheraton-Vistana-Resort-Villas.h23110.Hotel-Information) ![Universal's Cabana Bay Beach Resort](//images.trvl-media.com/lodging/6000000/5970000/5963300/5963292/63940f45_y.jpg) ### Universal's Cabana Bay Beach Resort 10/10 Excellent "Clean rooms with great access to pools" [](https://expedia.ca/Orlando-Hotels-Universals-Cabana-Bay-Beach-Resort.h5963292.Hotel-Information) ![DoubleTree by Hilton Hotel Orlando at SeaWorld](//images.trvl-media.com/lodging/1000000/20000/18900/18874/69019073_y.jpg) ### DoubleTree by Hilton Hotel Orlando at SeaWorld 10/10 Excellent "Clean rooms and property. The breakfast buffet was great. I would definitely stay there again" [](https://expedia.ca/Orlando-Hotels-DoubleTree-By-Hilton-Hotel-Orlando-At-SeaWorld.h18874.Hotel-Information) ![Fontainebleau Miami Beach](//images.trvl-media.com/lodging/2000000/1200000/1190600/1190549/4c5e4651_y.jpg) ### Fontainebleau Miami Beach 10/10 Excellent "Amazing luxury experience ! Bit overpriced resort food but worth it! " [](https://expedia.ca/Miami-Hotels-Fontainebleau-Miami-Beach.h1190549.Hotel-Information) ![Hilton Vacation Club Mystic Dunes Orlando](//images.trvl-media.com/lodging/1000000/900000/891000/890951/0b826e24_y.jpg) ### Hilton Vacation Club Mystic Dunes Orlando 10/10 Excellent "Clean by see" [](https://expedia.ca/Orlando-Hotels-Mystic-Dunes-Resort-Golf-Club-By-Diamond-Resorts.h890951.Hotel-Information) ![Gaylord Opryland Resort & Convention Center](//images.trvl-media.com/lodging/1000000/30000/21400/21317/bfce5669_y.jpg) ### Gaylord Opryland Resort & Convention Center 10/10 Excellent "We stayed in the Cascade wing, which was very accessible. The resort was clean and inviting and well kept. Dining was great, with a range of restaurant types. Shopping however was a little disappointing, each shop sold basically the same stuff. Not a lot of boutique or name brand items. Resort felt safe. Good value. Excited to return again! " [](https://expedia.ca/Nashville-Hotels-Gaylord-Opryland-Resort-Convention-Center.h21317.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels near Chatuge Lake](https://www.expedia.ca/Chatuge-Lake-Hotels.0-l6361294-0.Travel-Guide-Filter-Hotels) - [Hotels near Clarks Hill Lake](https://www.expedia.ca/Clarks-Hill-Lake-Hotels.0-l553248635976193722-0.Travel-Guide-Filter-Hotels) - [Hotels near Deals Gap](https://www.expedia.ca/Deals-Gap-Hotels.0-l553248635976197257-0.Travel-Guide-Filter-Hotels) - [Hotels near Elk River](https://www.expedia.ca/Elk-River-Hotels.0-l681967134005264384-0.Travel-Guide-Filter-Hotels) - [Hotels near Great Smoky Mountains National Park](https://www.expedia.ca/Great-Smoky-Mountains-National-Park-Hotels.0-l6025878-0.Travel-Guide-Filter-Hotels) - [Hotels near Hiwassee River](https://www.expedia.ca/Hiwassee-River-Hotels.0-l681967869528219648-0.Travel-Guide-Filter-Hotels) - [Hotels near Lake Seminole](https://www.expedia.ca/Lake-Seminole-Hotels.0-l553248635976194042-0.Travel-Guide-Filter-Hotels) - [Hotels near Tennessee River](https://www.expedia.ca/Tennessee-River-Hotels.0-l681069047849709568-0.Travel-Guide-Filter-Hotels) - [Flights to Cherohala Skyway](https://www.expedia.ca/Cheap-Flights-To-Cherohala-Skyway.d553248635997959187.Travel-Guide-Flights) - [Chatuge Lake](https://www.expedia.ca/Chatuge-Lake-United-States-of-America.d6361294.Vacation-Attraction) - [Great Smoky Mountains National Park](https://www.expedia.ca/Great-Smoky-Mountains-National-Park-United-States-of-America.d6025878.Vacation-Attraction) - [Car rentals near Great Smoky Mountains National Park](https://www.expedia.ca/Car-Rentals-In-Great-Smoky-Mountains-National-Park.d6025878.Car-Rental-Guide) - [Full-Size Car Rentals near Great Smoky Mountains National Park](https://www.expedia.ca/Fullsize-Car-Rentals-In-Great-Smoky-Mountains-National-Park.d6025878-tFullsize.Car-Rental-Guide-Class) - [Suv Car Rentals near Great Smoky Mountains National Park](https://www.expedia.ca/SUV-Car-Rentals-In-Great-Smoky-Mountains-National-Park.d6025878-tSUV.Car-Rental-Guide-Class) - [Book Spa Hotels in Southeastern United States on Expedia.com](https://www.expedia.com/Southeastern-United-States-Hotels-Spa-Hotel.0-0-d6209937-tSpaHotel.Travel-Guide-Filter-Hotels)