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Hotels in South Main, Houston from CA $55

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South Main hotels and places to stay

City view from property
The Whitehall Houston
4.0 star property
8.2 out of 10, Very good, (1001)
"I had a great one-night stay at the Whitehall. The room was well-appointed and very comfortable. The hotel is run by Sotherly and they had some nice touches - lemon cookies in the room, a veteran-focused foundation that they make you aware of, etc. The 1st floor bar, with an outside space, looked awesome. I just didn't have time to visit. The location is fine - a little on the outer edge of that side of downtown. I was close to my venue, so it was perfect for me. The only thing to note...
The price is CA $212
CA $249 total
includes taxes & fees
May 30 - May 31
The Whitehall Houston
Exterior
The Royal Sonesta Houston Galleria
4.0 star property
8.2 out of 10, Very good, (1005)
"Had a enjoyable time. Beautiful place, will come back "
The price is CA $244
CA $319 total
includes taxes & fees
May 24 - May 25
The Royal Sonesta Houston Galleria
Outdoor banquet area
C. Baldwin, Curio Collection by Hilton
4.0 star property
8.2 out of 10, Very good, (654)
"I brought a date for a one night turn around trip to Houston . The hotel was great and we hardly left the grounds between the food, bar & the atmosphere "
The price is CA $205
CA $272 total
includes taxes & fees
May 26 - May 27
C. Baldwin, Curio Collection by Hilton
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Lobby
Hyatt Place Houston Medical Center
3.0 star property
9.0 out of 10, Wonderful, (644)
"Everything was fine but the parking garage is confusing, you need arrows on the ground "
The price is CA $170
CA $199 total
includes taxes & fees
May 27 - May 28
Hyatt Place Houston Medical Center
Outdoor pool, pool umbrellas
Courtyard by Marriott Houston Medical Center/NRG Park
3.0 star property
8.6 out of 10, Excellent, (1003)
"Very nice rooms and very clean. Host was very courteous and most helpful. Check in was a breeze and we will certainly stay there again. Excellent stay. "
The price is CA $126
CA $148 total
includes taxes & fees
May 31 - Jun 1
Courtyard by Marriott Houston Medical Center/NRG Park
International cuisine
InterContinental Houston, an IHG Hotel
4.0 star property
9.4 out of 10, Exceptional, (1001)
"Very professional and polite staff. Room was very clean and updated. Very pleased with stay at this hotel. Will book there again! "
The price is CA $219
CA $276 total
includes taxes & fees
Jun 15 - Jun 16
InterContinental Houston, an IHG Hotel
Exterior
Springhill Suites by Marriott Houston Dwntn/Convention Cntr
2.5 star property
8.4 out of 10, Very good, (999)
"Great location "
The price is CA $149
CA $176 total
includes taxes & fees
May 30 - May 31
Springhill Suites by Marriott Houston Dwntn/Convention Cntr
Exterior
JW Marriott Houston Downtown
5.0 star property
9.2 out of 10, Wonderful, (1000)
"Excellent location particularly for Astros fans in town!"
The price is CA $311
CA $383 total
includes taxes & fees
Jun 16 - Jun 17
JW Marriott Houston Downtown
Exterior
Sonder The Hogg Palace
3.5 star property
8.4 out of 10, Very good, (611)
"booked this for my bday week and it immediately felt like a second home to me. I hope and I will to come back here again this same year. I wish I could live here permanently, it’s so perfect! that queen bed felt like a king to me. the wood floor did feel pretty fragile so i was kinda scared walking bc i didn’t wanna break any floors, but other than that, i’d love to come back to the same room and hopefully for longer."
The price is CA $159
CA $186 total
includes taxes & fees
Jun 5 - Jun 6
Sonder The Hogg Palace
Sports facility
Best Western Plus Downtown Inn & Suites
3.0 star property
9.4 out of 10, Exceptional, (1002)
"Super location "
The price is CA $172
CA $201 total
includes taxes & fees
May 23 - May 24
Best Western Plus Downtown Inn & Suites
Meeting facility
The Westin Oaks Houston at the Galleria
4.0 star property
8.8 out of 10, Excellent, (1003)
"The staff was on point! This hotel is in excellent proximity to eateries, lounges, and shopping plazas! We will definitely make this our go to hotel when visiting the Galleria area. "
The price is CA $293
CA $346 total
includes taxes & fees
May 24 - May 25
The Westin Oaks Houston at the Galleria
Outdoor pool, cabanas (surcharge), pool umbrellas
Four Seasons Hotel Houston
5.0 star property
9.2 out of 10, Wonderful, (1022)
"Awesome and Clean "
The price is CA $653
CA $768 total
includes taxes & fees
May 23 - May 24
Four Seasons Hotel Houston
Indoor pool
SureStay Plus Hotel by Best Western Houston Medical Center
2.5 star property
7.8 out of 10, Good, (1056)
"Our purpose was only to keep our appointments at MD Anderson. They had everything we needed including a very convenient shuttle service. The staff was very friendly and helpful. "
The price is CA $147
CA $172 total
includes taxes & fees
May 24 - May 25
SureStay Plus Hotel by Best Western Houston Medical Center
LCD TV, pay movies, MP3 dock
Homewood Suites by Hilton Houston Near the Galleria
3.0 star property
8.4 out of 10, Very good, (1002)
"Nice property in a good location. Staff was friendly and accommodating. "
The price is CA $156
CA $184 total
includes taxes & fees
May 30 - May 31
Homewood Suites by Hilton Houston Near the Galleria
Desk, blackout drapes, iron/ironing board, free rollaway beds
Hampton Inn Houston-Near The Galleria
2.5 star property
7.8 out of 10, Good, (1001)
"Property had a very friendly staff."
The price is CA $138
CA $162 total
includes taxes & fees
May 27 - May 28
Hampton Inn Houston-Near The Galleria
Exterior
Days Inn & Suites by Wyndham Downtown/University of Houston
2.0 star property
8.0 out of 10, Very good, (488)
"We liked that it was clean, reasonably priced and close to the University of Houston. They had a good breakfast as well. "
The price is CA $91
CA $107 total
includes taxes & fees
Jun 3 - Jun 4
Days Inn & Suites by Wyndham Downtown/University of Houston
Breakfast, lunch, dinner served; southern cuisine
Houston Marriott West Loop by The Galleria
4.0 star property
8.2 out of 10, Very good, (731)
"Friendly staff. Rooms could be updated "
The price is CA $195
CA $232 total
includes taxes & fees
May 23 - May 24
Houston Marriott West Loop by The Galleria
Exterior
Residence Inn by Marriott Houston by The Galleria
3.0 star property
8.0 out of 10, Very good, (672)
"Shopping "
The price is CA $119
CA $140 total
includes taxes & fees
May 27 - May 28
Residence Inn by Marriott Houston by The Galleria
Lobby
Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
6.2 out of 10, (1000)
"They can do a better breakfast then just fruit bar and coffee"
The price is CA $104
CA $122 total
includes taxes & fees
May 19 - May 20
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Business centre
OYO Hotel Houston Tx Medical Center Nrg Stadium
2.5 star property
4.0 out of 10, (377)
"Nothing short of amazing shall I say 😂"
The price is CA $55
CA $70 total
includes taxes & fees
May 30 - May 31
OYO Hotel Houston Tx Medical Center Nrg Stadium
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See all available properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Main

Hotels in top Houston neighborhoods Learn more about South Main
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

3 out of top 10 points of interest in this area
4/5(79 area reviews)

Known for its abundant dining options and live music, there's plenty to explore in Downtown Houston. Top attractions like Toyota Center and Minute Maid Park are major draws, and you can catch the metro at Central Station Main or Theater District Station to see more of the city.

Find hotels in Downtown Houston

Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center, an IHG Hotel and Wyndham Houston near NRG Park/Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 90 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.

Recent Reviews in South Main

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

5/5 Excellent
"The rooms aren’t as clean as I expected. "
A verified traveller stayed at Club Quarters Hotel Downtown, Houston
Posted 2 days ago
Club Quarters Hotel Downtown, Houston