Title: 10 Best Hotels in South Main, Houston for 2026 | Expedia.ca

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# Hotels in South Main, Houston 

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## Go beyond your typical stay in South Main

Apart hotel

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&lodging=APART_HOTEL)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&travelerType=family_friendly)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&lodging=APARTMENT)

Spa

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&amenities=SPA_ON_SITE)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&amenities=POOL)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&amenities=HOT_TUB)

Condo

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&lodging=CONDO)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&amenities=PETS)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&amenities=WATER_PARK)

Villa

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&lodging=VILLA)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-12-17&d1=2025-12-17&endDate=2025-12-19&d2=2025-12-19&lodging=COTTAGE)

## Check prices for these dates

Tonight

[Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-12-03&endDate=2025-12-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 4 - Dec 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-12-04&endDate=2025-12-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## South Main hotels and places to stay

![Lobby](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/0afdb877.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/a1271476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/d9fe05fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/d9a5db5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Houston near Medical Center- NRG Stadium

South Main

8.6/10

Excellent

(1011)

"Was a great stay and rigjt next to the stadium all around recomended"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jason

CA $130

CA $152 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information)

![Hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/3135be14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/1e7f9dd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/572f60ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/c101e36a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites NRG Park - Medical Center

South Main

6.6/10

(1000)

"Everything was great"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Yeimi

CA $87

CA $102 total

includes taxes & fees

Dec 30 - Dec 31

[](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/a95a0099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/ad9ee504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/793de3f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/dcd59221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Houston near NRG Park/Medical Center

South Main

7.2/10

Good

(1195)

"Love this place. Been staying here for many years. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Reynaldo

CA $182

CA $212 total

includes taxes & fees

Dec 4 - Dec 5

[](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information)

![Gazebo](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/ab4b9445.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/6b2e094a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/98547457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/54d3b468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wingate Houston near NRG Park/Medical Center

South Main

6.6/10

(984)

"Great staff, excellent service and convenient to the area we were wanting to be. Room was clean and bed was very comfortable."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Roy

CA $180

CA $211 total

includes taxes & fees

Dec 4 - Dec 5

[](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/168bdeac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/b0f701b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/14da1a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/13fb2418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Candlewood Suites Houston Medical Center by IHG

South Main

7.4/10

Good

(820)

"Yes the where"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

CA $88

CA $103 total

includes taxes & fees

Dec 24 - Dec 25

[](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/1dfc3b1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/e09cf385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/6748ac8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/125b6430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Place Houston Medical Center

Texas Medical Center, 3.1 km from South Main

9.2/10

Wonderful

(2156)

"Nice hotel, excellent rooms with comfy beds! Only stayed one night but definitely a nice place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carey

CA $162

CA $191 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/Houston-Hotels-Hyatt-Place-Houston-Medical-Center.h88130440.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/db7ae93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/d347e4bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/b2836bab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/40a5bc26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Blossom Hotel Houston, Curio Collection by Hilton

Texas Medical Center, 3.5 km from South Main

9.0/10

Wonderful

(3615)

"We had a great time at the hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniel

CA $184

CA $215 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/f81e2b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/e6bebcd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/7c5c6c1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/536185d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt House Houston Medical Center

Texas Medical Center, 3.1 km from South Main

9.2/10

Wonderful

(1176)

"I had a great stay! I travel to Houston several times a year and this is one of my favorite places to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Star

CA $162

CA $190 total

includes taxes & fees

Jan 3 - Jan 4, 2026

[](https://www.expedia.ca/Houston-Hotels-Hyatt-House-Houston-Medical-Center.h83750993.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13300/13295/c40a6103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Composer) | Dining room](https://images.trvl-media.com/lodging/1000000/20000/13300/13295/f9f8ae11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, free minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/13300/13295/a617bbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/13300/13295/dd9a3669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Lancaster Hotel

Downtown Houston, 11.1 km from South Main

9.8/10

Exceptional

(1000)

"Great amenities and hospitality "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Varun

CA $272

CA $319 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Houston-Hotels-The-Lancaster-Hotel.h13295.Hotel-Information)

![Sundeck](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f8ddb5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/8964faa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f2e085ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Houston Plaza/Medical Center

4.4 km from South Main

8.4/10

Very good

(1717)

"Clean rooms, comfortable bed, & friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thomas

CA $129

CA $153 total

includes taxes & fees

Dec 22 - Dec 23

[](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information)

![Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/9a708987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/55e246fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/e4ab6d84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/b1e04b0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Houston/Galleria

The Galleria, 8.7 km from South Main

9.0/10

Wonderful

(1159)

"Confortable bed, quiet ron and nice breakfast!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Juan

CA $180

CA $253 total

includes taxes & fees

Dec 12 - Dec 13

[](https://www.expedia.ca/Houston-Hotels-Hyatt-Regency-HoustonGalleria.h10620692.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/109ddc6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/ec3f4d74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Down comforters, in-room safe, blackout drapes, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/71078c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton Hotel & Suites Houston by the Galleria

8.9 km from South Main

8.2/10

Very good

(3020)

"Great hotel. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Duane

CA $174

CA $205 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/w3840h2429x0y4-3c0050af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 6:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/2272dc89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/w3840h2556x0y4-ddcde99b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Royal Sonesta Houston Galleria

The Galleria, 8.8 km from South Main

8.4/10

Very good

(1434)

"Great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Curtis

CA $180

CA $211 total

includes taxes & fees

Dec 19 - Dec 20

[](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/3cd063c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/ba6c768a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/8c22d1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/e16d70bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Whitehall Houston

Houston Central Business District, 10 km from South Main

8.6/10

Excellent

(1895)

"Great stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anita

CA $155

CA $182 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/8293c765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Snack bar](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/b3a01060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/cadce26d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/07164eba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Houston Medical Center, TX

Texas Medical Center, 4.7 km from South Main

9.4/10

Exceptional

(1018)

"Clean room and nice staff"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Guillermo

CA $144

CA $169 total

includes taxes & fees

Dec 22 - Dec 23

[](https://www.expedia.ca/Houston-Hotels-Hilton-Garden-Inn-Houston-Medical-Center.h66425729.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/e83f776d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, individually furnished, desk](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/b72d00fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/29e4bd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/efa6f907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InterContinental Houston by IHG

Texas Medical Center, 4.1 km from South Main

9.2/10

Wonderful

(1000)

"Clean room, excellent staff, kind and respectful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

DIANA

CA $164

CA $220 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Houston-Hotels-InterContinental-Houston-Medical-Center.h23830866.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/73000000/72510000/72510000/72509948/02126088.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, soundproofing](https://images.trvl-media.com/lodging/73000000/72510000/72510000/72509948/a772e6cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/73000000/72510000/72510000/72509948/7f2b0483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/73000000/72510000/72510000/72509948/40188cb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Houston – Downtown North by IHG

Northside, 13.7 km from South Main

9.2/10

Wonderful

(613)

"Nice staff and very clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Luis

CA $139

CA $162 total

includes taxes & fees

Dec 19 - Dec 20

[](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Express-Suites-Houston-N-Downtown.h72509948.Hotel-Information)

![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/e02c73c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/18c0750c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/be7d736f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/8863ac84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Haven Inn & Suites Downtown Houston

North Houston, 18.8 km from South Main

9.4/10

Exceptional

(1000)

"Very clean and safe, would stay again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Krimson

[](https://www.expedia.ca/Houston-Hotels-Haven-Inn-Suites-Downtown-Houston.h18122141.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/33000000/32710000/32701900/32701841/ac108c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/33000000/32710000/32701900/32701841/0ca2f795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/33000000/32710000/32701900/32701841/532fe87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/33000000/32710000/32701900/32701841/adf4ab30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Houston - Memorial City Centre by IHG

18.4 km from South Main

8.8/10

Excellent

(1000)

"Clean, quiet and will return "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lauren

CA $133

CA $156 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Express-Suites-Houston-Memorial-City-Centre.h32701841.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/51d97881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/8cd20a4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/w3840h2558x0y0-562426d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Americas-Houston

10.4 km from South Main

9.4/10

Exceptional

(1592)

"Clean, great location and super convenient food options!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Valerie

CA $197

CA $234 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-17&endDate=2025-12-18&regionId=553248635976386992&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most. 

- Downtown Houston
- The Galleria
- Texas Medical Center
- Montrose
- Northside

![Discovery Green which includes city views, a square or plaza and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23540-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Discovery Green showing a park, a skyscraper and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34453-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/507000/507468-downtown-houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/507000/507497-downtown-houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Discovery Green showing a statue or sculpture, a high-rise building and modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34451-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800037)

![Downtown Houston map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:s%7CrtDz%7BbeQiQ_%40eEcBgCkDuQ%7D_%40m%5EeQ%7EMi%5DoAePiLi%60%40m%40%7DTlCsl%40pNj%5CxWzUxS%60Bv%7CAhmAcg%40ncAuI%60DmZx%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=WgKNf3zxiTWREKGzy8I1t3uy5Hs=)

### Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800037)

![](https://mediaim.expedia.com/destination/1/733d46a93b53c864b5c00945f6416b51.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/d7dc12b9d267be169566d38db8ea7eac.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/01538c9f6eb646ea96e3df2059618b27.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/374a9a687602bd093583e97522a04bc6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/9/aadfd687906d99829a520409ec046d47.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=501263)

![The Galleria map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7DxptDn%7DteQ_AcXqKr%40mHsB%7BXT%5DgYeZY%3F%7D%60%40jGi%40rA_HxCyFTuIpzAsBbBt%7D%40fw%40%60NdA%7Ce%40szAdB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5e77b0krOIeDwBK5_jkO84swezY=)

### The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=501263)

![](https://mediaim.expedia.com/destination/1/f4655cac96c82fca6c00f4ab3162178c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/29187be13ac57fa24b0f672247c7afbc.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/52a59f2a0bfb2cf153bbc44f917f7275.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/9/921ad7f5733a42c9202d8d16c78f3830.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6143504)

![Texas Medical Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wbftD%7C%60keQyBu%40u%5DkXgZySqC%7EG%7DEnG%7DQrDyAw%60%40aa%40gYrCsKe%5BcW%7CM_UbGi%40%60LmLjQmE%5DmPvB%60%40vEoQhGyJnDgKjKlC%7DDbTqAUq%40lDrYtHbGdd%40nKsDlOe%40bW%60Oj%40d_%40%7BFd%40%3FdRmCpA%3FdAtC%7CDL%60_%40eF%3F%7B%40uFiDf%40AqAwBB%7BC%60Ae%40yCm%40OlBhOjId%60%40hAnC&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=-txg4h32BKxrIPBjQzTWKWRnz0I=)

### Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6143504)

![Menil Collection which includes interior views and art](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23619-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Menil Collection featuring interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23623-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Menil Collection showing interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34667-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Menil Collection featuring a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34665-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34668-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=3000663145)

![Montrose map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wiptDf%7CieQmBWy%7E%40R%7BAe%40qByG_CiCwQJiG%60%40X%7BBoAyGIeOwDsLe%40qDh%40uJ%7D%40sCSsDuCkJJyE%60AsGLaMnD%7DQBcLreAQGwItTKI_MvFAb%40a%40rNdApW%40nf%40l%5D%60BlBnFpdBf%40tTElUyoA%5C&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=FA9GMjOoslAVD7SwHDyMnspJbfU=)

### Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663145)

![](https://mediaim.expedia.com/destination/7/b249298face16fd5795cf74face8ed8d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/7f180593ef78263134eb6f20e72fd6c3.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635976387525)

![Northside map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:muquD%60e%7DeQS_uAwHCiF%7B%40eOkIi%40dAf%40oAhOnIfFz%40%7CHB%3Ff%40bqCs%40%3FqP%7CBA%3FgKkUFzCeb%40%60u%40%5BJlx%40tq%40%3FV%7BOrD_GhAsKxG%7BG%40aB%7DS%7CJwIgSn%5Bo%5Bc%60A%5EUanAmEqAsFwCcGr%40yITqExA%7BBMQkXpJAEkNiFDBaS%7EFaJ%7E%5Eq%5EoBszBgmA%5Ci%40myAgFF%3FeAiDFIoIsYFYcEaBmFuoAj%40eaAgCNf%60%40__AZZzv%40hGx%5Ez%40VJvAk%40l%40HnI%7DQD%40pkA%60%40rMqSJ%3FfEoB%40AgEsKB_%40k%7EAaEyFoC%3F_EkEcEuCtCAY_SmKBBbIqHDgDgDu%40mBGcFnPF%60J_%40CwLqy%40ZD%7Ef%40aG%40%40tMw%40bJEvGcq%40RJyg%40aLC%3FsBzBcFjHC%3Fs%5DkFnBwCxBiS%60W_D%3FW%7Bl%40zd%40mG%3FmGlLM%3FbD%7ENoBhi%40i%40bVaArH%7D%40o%40geB%7DXJMif%40fJGUux%40tdCy_%40vB%7ERj%40dRlOEDtK%7BOHC%7EKnBA%40%7CK%60bBi%40x%40dbBpIVltA%7D%40jIn%40nmCg%40i%40mgCOgAiM%7EG%5D%7BqAmFC%3FrCcHA%40nC%7D%5E%40CaQaVT%40%5EsNaMoARg%40wGj%5DwEl%60A%7DOOe%5D%7EHAHzZdScDvJVw%40csCiLcAcDfBcDf%40Iyh%40jVOHwZvZvNMqfBayCg%7D%40Sc%60%40kq%40E%40u%40%7DF%40AqEyP%3FKkWkZNI%7DZee%40Zl%40eF%7CBC%40%60C%60D%3FGiVxpAk%40NpO%60KIPbn%40ve%40O%5Bqz%40jd%40OEya%40vLEAmHts%40W%5Da_B%60lCrjCjZ_CtfB%7CAXsObgDc%40JxYj%5E%5EpaAzrCvuCXjEtQfl%40vZqG%60R%7DN%7EP%7C%40%7CUhHdSmSrCuBzWvDzNeEbf%40uYnGwRwe%40cCd_ArSfu%40s%60%40%7E%60%40u_%40%7EZiKhk%40dQtm%40uAxaB_JDIpSkK%7CJfFfLC%7EHsK%7DBku%40dDj%40fJaLmAApX%7CLxDcItPeIlFuF%7CNkc%40fN%7BOpNoA%7E%5BsLdPiPjb%40ut%40nYq%40ti%40gNr%5EbAlaAsfC%7EwCkDKw%40mJtCcGavBu%40aZuJoEBn%40%7C%7EAyq%40%5CgCp%5C%7B%60B%3F%5DcfAgwCbuA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=SL4qRZsnUhbIVHkfA1was5maM1w=)

### Northside

While you're in Northside, take in top sights like The Heights Theater or Greenspoint Mall, and hop on the metro to see more the city at Northline Transit Center/HCC Station or Melbourne/North Lindale Station. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976387525)

## Top South Main Hotel Reviews

![Blossom Hotel Houston, Curio Collection by Hilton](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/db7ae93f_y.jpg)

### Blossom Hotel Houston, Curio Collection by Hilton

10/10 Excellent

"Everything about our stay was excellent. "

[](https://expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information)

![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg)

### Hilton Houston Plaza/Medical Center

10/10 Excellent

"Great"

[](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information)

![Magnolia Hotel Houston, A Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg)

### Magnolia Hotel Houston, A Tribute Portfolio Hotel

10/10 Excellent

"Good location, beautiful room and seamless checkin"

[](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information)

![SpringHill Suites by Marriott Houston Intercontinental Arprt](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/69d373fc_y.jpg)

### SpringHill Suites by Marriott Houston Intercontinental Arprt

10/10 Excellent

"Great hotel, good price, clean and close to the hotel "

[](https://expedia.ca/Houston-Hotels-SpringHill-Suites-By-Marriott-Houston-Intercontinental-Arprt.h2964240.Hotel-Information)

![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191_y.jpg)

### Crowne Plaza Houston Med Ctr-Galleria Area by IHG

10/10 Excellent

"My room was very clean and the service outstanding"

[](https://expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information)

![DoubleTree by Hilton Hotel Houston - Greenway Plaza](https://images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg)

### DoubleTree by Hilton Hotel Houston - Greenway Plaza

10/10 Excellent

"Great room, quiet and elegant. Enjoyed the stay greatly. "

[](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information)

![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg)

### The Royal Sonesta Houston Galleria

10/10 Excellent

"Great service "

[](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information)

![The Whitehall Houston](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg)

### The Whitehall Houston

10/10 Excellent

"Kelvin chatted with me and upgraded our room because we were celebrating a late honeymoon! "

[](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information)

![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg)

### Club Quarters Hotel Downtown, Houston

10/10 Excellent

"The room was very clean. The staff was outstanding!"

[](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information)

## Frequently asked questions

### What are the best hotels in South Main that travellers recommend?

> For families, [Wingate Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) is another great option. With a complimentary continental breakfast to fuel your adventures and a refreshing outdoor pool, it caters superbly to parents and kids alike. The accessible fitness centre allows for some family fun, while the hotel's pet-friendly policies make it a fantastic choice for those traveling with furry companions. With a focus on convenience and value, this hotel provides excellent amenities while keeping everyone comfortable.

### What are the best family hotels in South Main?

> Another excellent option is the [Candlewood Suites Houston Medical Center by IHG](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information), which boasts a family-friendly atmosphere with its free cribs, connecting rooms, and a sofa bed, making it great for families needing extra space. Guests appreciate the convenience of in-room kitchen amenities like a microwave and dishwasher, allowing for easy meal prep during your stay. It has a review score of 7.6, reflecting its appeal to families on the go.
> 
>   
> For those seeking a place with a pool, the [Quality Inn & Suites NRG Park - Medical Center](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information) is a great choice. With its inviting pool area, free meals for children, and options for rollaway beds at no extra charge, families can enjoy a splash-filled vacation while also benefiting from daily housekeeping and snack options.
> 
>   
> Lastly, the [Wyndham Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) features child-friendly window designs and connecting rooms, catering specifically to families' needs. The presence of kitchenettes adds to the convenience, allowing families to prepare snacks or meals together. This property has a traveller rating of 7.2, making it a reliable choice for family stays.
> 
>   
> These hotels exemplify quality and convenience, ensuring that your family's adventure in South Main is both enjoyable and comfortable.

### What hotels in South Main offer free breakfast?

> Another great choice is [Quality Inn & Suites NRG Park - Medical Center](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information), which also provides a free breakfast, including options for those on the go. This family-friendly hotel offers spacious suites with balconies and patios, allowing families to unwind outdoors. The outdoor pool invites guests to relax and enjoy the Texas sunshine, while the complimentary area shuttle makes it simple to explore the attractions nearby.
> 
>   
> For those traveling without children, the [Wingate Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) presents a delightful blend of comfort and accessibility. With an outdoor pool and fitness centre, it caters to adults looking for a rejuvenating getaway. The hotel's continental breakfast is another perk that guarantees a satisfying start to your morning adventures.

### What are the best budget hotels in South Main?

> For another appealing choice, [Candlewood Suites Houston Medical Center by IHG](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information) stands out with a review score of 7.6\. This property is superb for families, as it features kitchenettes in the rooms, allowing for meal preparation and snacks on the go. Kids can also enjoy the complimentary cribs and sofa beds, making it a comfortable stay for everyone. Additionally, the hotel offers a free area shuttle, which is great for exploring local attractions without the hassle of driving.
> 
>   
> If you're traveling with your partner or friends, the [Wyndham Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) offers a more relaxed atmosphere with a lower review score of 7.2\. This hotel features outdoor pool access and convenient amenities, including a kitchenette in some rooms, which can appeal to those looking for a home-like experience while away.
> 
>   
> No matter your travel group, these options in South Main cater to various needs while ensuring a comfortable and enjoyable stay.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a South Main hotel booking with Expedia?

### How much is the nightly rate at a South Main hotel?

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