Title: Visit South Main: Best of South Main, Houston Travel 2026 | Expedia Tourism - Expedia.ca [Hotels in South Main](https://expedia.ca/South-Main-Houston-Hotels.0-n553248635976386992-0.Travel-Guide-Filter-Hotels)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[South Main Car Rentals](https://expedia.ca/Car-Rentals-In-South-Main.d553248635976386992.Car-Rental-Guide)[South Main Vacations](https://expedia.ca/South-Main.d553248635976386992.Destination-Travel-Guides) # South Main ## Houston ![Aerial view of Hermann park in Houston with Japanese Garden, zoo, Space Adventure playground](https://images.trvl-media.com/place/553248635976386992/633bd53d-8369-45ed-9507-93d6ecf02186.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![South Main](https://images.trvl-media.com/place/1503/2eeb9f80-ebf6-42ad-9574-1d77038420db.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit South Main Things to do Hotels Where to stay [Houston travel guide](https://expedia.ca/Houston.dx178265) --- ### Popular places to visit ![Texans Vs Bears ](https://images.trvl-media.com/place/1503/e9e0c365-cf4d-4e4b-b714-f9dd65c34baf.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### NRG Stadium 4.5/5(10 reviews) Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [](https://expedia.ca/NRG-Stadium-Astrodome.d553248635929331916.Vacation-Attraction) ![NFL Experience](https://images.trvl-media.com/place/1503/79f85336-9389-4f19-a086-bdba1925534e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### George R. Brown Convention Center 4/5(23 reviews) During your trip, find out what's happening at George R. Brown Convention Center, a top convention center in Houston. Experience the entertainment choices and acclaimed art scene in this vibrant area. [](https://expedia.ca/George-R-Brown-Convention-Center-Houston.d501247.Vacation-Attraction) ![Houston_MinuteMaidPark_6034772_1](https://images.trvl-media.com/place/6034772/6d7d1cbe-28b6-4078-86cd-2bb274c4f722.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Daikin Park 4.5/5(29 reviews) Catch an event at Daikin Park during your trip to Houston. Experience the entertainment choices and lively festivals in this vibrant area. [](https://expedia.ca/Daikin-Park-Downtown-Houston.d6034772.Vacation-Attraction) ![At the main entrance.](https://images.trvl-media.com/place/1503/00b4e1ca-e78a-46ba-93de-a793739a6117.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Toyota Center 4/5(24 reviews) Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed theater scene and entertainment choices in this vibrant area. [](https://expedia.ca/Toyota-Center-Downtown-Houston.d6082241.Vacation-Attraction) ![Space Center Houston which includes interior views](https://images.trvl-media.com/place/6163111/0a492b74-6d09-47ca-8bcb-439f43fd5709.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Space Center Houston 4.5/5(66 reviews) This iconic “mission control” was immortalized for its role in the first moon landing. [](https://expedia.ca/Space-Center-Houston-Nassau-Bay.d6163111.Vacation-Attraction) ![www.alamy.com](https://images.trvl-media.com/place/501253/9f806038-e019-4ef0-8e59-8c564c0cb29c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### NASA Johnson Space Center 4.5/5(81 reviews) After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event. [](https://expedia.ca/NASA-Johnson-Space-Center-Nassau-Bay.d501253.Vacation-Attraction) ### Things to do ![Houston Space Center](https://mediaim.expedia.com/localexpert/1341309/02135dd9-3195-40c1-a500-25efe978e608.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Space Center Houston Admission Ticket CA $45 per adult **92%** of travellers recommend [](https://expedia.ca/things-to-do/space-center-houston-admission-ticket.a1341309.activity-details) ![Astroville Tunnel Tour of Downtown Houston](https://mediaim.expedia.com/localexpert/1358845/93d97319-081a-4fec-9e57-9de4737dfee7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Astroville Tunnel Tour of Downtown Houston (Air-Conditioned) CA $34 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/astroville-tunnel-tour-of-downtown-houston-air-conditioned.a1358845.activity-details) ![Houston: Sloomoo Institute Entry Ticket](https://mediaim.expedia.com/localexpert/48181877/0194cadc-0356-4ecd-a787-6fed90663fc8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston: Sloomoo Institute Entry Ticket CA $44 per adult [](https://expedia.ca/things-to-do/houston-sloomoo-institute-entry-ticket.a48181877.activity-details) ![Houston Museum of Natural Science: Cockrell Butterfly Center](https://mediaim.expedia.com/localexpert/44625315/13581a0d-ea47-46d7-8fcf-d3fc7aa4909c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Museum of Natural Science: Butterfly Center Ticket CA $21 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/houston-museum-of-natural-science-butterfly-center-ticket.a44625315.activity-details) ![Houston: Museum of Natural Science General Admission Ticket](https://mediaim.expedia.com/localexpert/44624726/7df2f7a9-1343-48ce-acab-88df62f142d4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Museum of Natural Science General Admission Ticket CA $34 per adult **98%** of travellers recommend [](https://expedia.ca/things-to-do/houston-museum-of-natural-science-general-admission-ticket.a44624726.activity-details) ![Houston: Holocaust Museum Houston Entry Ticket](https://mediaim.expedia.com/localexpert/47985204/cc6c178c-7c2f-47f0-8536-736f4d600e99.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston: Holocaust Museum Houston Entry Ticket CA $30 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/houston-holocaust-museum-houston-entry-ticket.a47985204.activity-details) [See all activities in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities) --- ## South Main Hotel Deals ![Wyndham Houston near NRG Park/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/99a71929_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Wyndham Houston near NRG Park/Medical Center 8686 Kirby Drive Houston TX CA $127 CA $149 total Apr 5 - Apr 6 includes taxes & fees Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful staff ... 7/10 Good! (1,263 reviews) Thankful for very last minute accommodation when our VRBO and host were not accessible, but can't ever remember having to pay 40.00 for parking for each car. Unfortunate and expensive pivots for this one night stay! May have been better off driving the 3+ hours back home. Reviewed on Mar 23, 2026 [](https://expedia.ca/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=21297&PinnedHotelID=21297&HadPinnedHotel=true®ionId=553248635976386992) ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/109ddc6c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 5353 Westheimer Rd Houston TX CA $143 CA $168 total Apr 5 - Apr 6 includes taxes & fees Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ... 8.4/10 Very Good! (3,606 reviews) Everything was not price correctly nor was the property clean Reviewed on Mar 23, 2026 [](https://expedia.ca/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=20116&PinnedHotelID=20116&HadPinnedHotel=true®ionId=553248635976386992) ![Hotel Zaza Houston Museum District](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/0f950f88_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Zaza Houston Museum District 5701 Main Street Houston TX Book a stay at this luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ... 9/10 Wonderful! (1,926 reviews) Great vibe Reviewed on Mar 22, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=07%2F04%2F2026&endDate=08%2F04%2F2026&selected=3306&PinnedHotelID=3306&HadPinnedHotel=true®ionId=553248635976386992) [](https://expedia.ca/Hotel-Search?startDate=07%2F04%2F2026&endDate=08%2F04%2F2026&selected=3306&PinnedHotelID=3306&HadPinnedHotel=true®ionId=553248635976386992) ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/5506d9bf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Royal Sonesta Houston Galleria 2222 West Loop South Houston TX CA $168 CA $197 total Apr 18 - Apr 19 includes taxes & fees Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ... 8.6/10 Excellent! (1,711 reviews) I had a great stay Reviewed on Mar 24, 2026 [](https://expedia.ca/Hotel-Search?startDate=18%2F04%2F2026&endDate=19%2F04%2F2026&selected=878652&PinnedHotelID=878652&HadPinnedHotel=true®ionId=553248635976386992) ![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/d170df91_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Club Quarters Hotel Downtown, Houston 1085 Rusk Street Houston TX CA $136 CA $159 total Apr 9 - Apr 10 includes taxes & fees Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ... 8.6/10 Excellent! (4,070 reviews) Perfect Reviewed on Mar 23, 2026 [](https://expedia.ca/Hotel-Search?startDate=09%2F04%2F2026&endDate=10%2F04%2F2026&selected=1156923&PinnedHotelID=1156923&HadPinnedHotel=true®ionId=553248635976386992) ![Blossom Hotel Houston, Curio Collection by Hilton](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2505x3y0-1cfabad9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Blossom Hotel Houston, Curio Collection by Hilton 7118 Bertner Ave Houston TX CA $220 CA $258 total Apr 12 - Apr 13 includes taxes & fees Book a stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges, and a rooftop terrace. Our guests praise the pool and the helpful staff in ... 9/10 Wonderful! (3,759 reviews) I love the blossom. The only hotel i will stay everytime im in houston Reviewed on Mar 24, 2026 [](https://expedia.ca/Hotel-Search?startDate=12%2F04%2F2026&endDate=13%2F04%2F2026&selected=58985846&PinnedHotelID=58985846&HadPinnedHotel=true®ionId=553248635976386992) [See all 6,405 properties in South Main](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=25%2F03%2F2026&endDate=26%2F03%2F2026®ionId=553248635976386992) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check South Main hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=2026-03-24&endDate=2026-03-25)[Mar 24 - Mar 25](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=2026-03-24&endDate=2026-03-25) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=2026-03-25&endDate=2026-03-26)[Mar 25 - Mar 26](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=2026-03-25&endDate=2026-03-26) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026)[Mar 27 - Mar 29](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[Apr 3 - Apr 5](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026) --- ### Other neighbourhoods around South Main ![Whether or not you're a little bit country, Rodeo Houston is a BLAST!! Each spring you're able to grab some great BBQ, catch some live country music acts, and check out the good looking cowboys riding for 8 seconds of fame!! A Texas MUST DO!](https://images.trvl-media.com/place/1503/18186f36-2267-4279-b375-1bb94762cced.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Astrodome 5/5(1 area review) If you're spending time in Astrodome, check out sights like NRG Stadium or NRG Astrodome and hop on the metro to see more the city at Stadium Park/Astrodome Station or Smith Lands Station. [](https://expedia.ca/Houston-Astrodome.dx553248635976007975) ![Aerial view of Hermann park in Houston with Japanese Garden, zoo](https://images.trvl-media.com/place/6143504/f45257e8-ab2c-4d2e-9332-ef0898a9cb17.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Texas Medical Center 4.5/5(2 area reviews) Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience. [](https://expedia.ca/Houston-Texas-Medical-Center.dx6143504) ![TMC](https://images.trvl-media.com/place/1503/58fd4720-60ea-4071-96b7-0d260c453508.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Museum District Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city. [](https://expedia.ca/Houston-Houston-Museum-District.dx6164045) ![TMC](https://images.trvl-media.com/place/1503/58fd4720-60ea-4071-96b7-0d260c453508.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### South Central Houston 5/5(1 area review) If you're spending time in South Central Houston, check out sights like Children's Museum of Houston or Houston Natural Science Museum and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station. [](https://expedia.ca/Houston-South-Central-Houston.dx553248635976476176) ![EyeEm Custom Shoots Q4 2018](https://images.trvl-media.com/place/3000663145/5fc14982-6419-4f20-a21b-2dee7a209053.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Montrose 3.5/5(4 area reviews) Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area. [](https://expedia.ca/Houston-Montrose.dx3000663145) ![White Oak and Buffalo Bayou Rivers confluence, Downtown Houston, Texas, United States of America](https://images.trvl-media.com/place/553248635074842911/efd49955-b5d4-4334-9f25-c05c51a02456.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### River Oaks Gardens and monuments are just a few things travelers like about River Oaks. A stop by River Oaks Country Club is also recommended if you've got time to explore the area. [](https://expedia.ca/Houston-River-Oaks.dx553248635074842911) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # South Main ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app