South Main
Houston
Visit South Main
Things to do
Houston's Official City & Mural Tour!
CA $64
per adult
88% of travellers recommend
Houston: Space Center Houston Admission Ticket
CA $43
per adult
92% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
CA $155
per adult
92% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
CA $43
per adult
96% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
CA $17
per adult
Meow Wolf's Radio Tave in Houston
CA $57
per adult
84% of travellers recommend
South Main Hotel Deals
Wyndham Houston near NRG Park/Medical Center
8686 Kirby Drive Houston TX
The price is CA $126 per night from Aug 3 to Aug 4
CA $126
CA $148 total
Aug 3 - Aug 4
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful staff ...
7/10 Good! (1,335 reviews)
"I was very disappointed with my stay at this hotel. The property is extremely dated, from the old furniture to the worn-out bathroom, and it feels like it hasn’t been updated in years. Even basic amenities were lacking—there wasn’t a smart TV, and no shampoo or towels were provided until I specifically ..."
Reviewed on Jul 10, 2026
Hotel Zaza Houston Museum District
5701 Main Street Houston TX
The price is CA $286 per night from Jul 12 to Jul 13
CA $286
CA $398 total
Jul 12 - Jul 13
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,014 reviews)
"Gorgeous view from the balcony! Bed and linens super comfortable. The steam shower was absolutely heavenly, water pressure and temp SOOOOO good!! Room service and food was great, and I loved how helpful the staff was. They brought by ice, water, and a snack without me asking once I had been there ..."
Reviewed on Jul 9, 2026
Grand Tuscany Hotel
12801 Northwest Fwy Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $131 per night from Jul 19 to Jul 20
CA $131
CA $154 total
Jul 19 - Jul 20
includes taxes & fees
Book a stay at this family-friendly hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the pool and the helpful ...
8/10 Very good! (159 reviews)
"Pool was way too small."
Reviewed on Jul 9, 2026
Club Quarters Hotel Downtown, Houston
1085 Rusk Street Houston TX
The price is CA $129 per night from Jul 25 to Jul 26
CA $129
CA $151 total
Jul 25 - Jul 26
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,336 reviews)
"The service was great! Everyone was so kind and attentive."
Reviewed on Jul 11, 2026
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
5353 Westheimer Rd Houston TX
The price is CA $185 per night from Aug 10 to Aug 11
CA $185
CA $217 total
Aug 10 - Aug 11
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very good! (4,251 reviews)
"Great property for a solo traveler"
Reviewed on Jul 10, 2026
Marriott Marquis Houston
1777 Walker Street Houston TX
The price is CA $338 per night from Aug 3 to Aug 4
CA $338
CA $436 total
Aug 3 - Aug 4
includes taxes & fees
Book a stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,162 reviews)
"Loved this hotel. Probably the nicest hotel I have ever stayed at and I am very well traveled. The pool was incredible and everything we imagined, plenty of food options available on site, and staff were very friendly. Would book again in a heartbeat!"
Reviewed on Jul 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Main
Find the best South Main areas and neighborhoods for the activities you enjoy most.
Downtown Houston
Known for its abundant dining options and live music, there's plenty to explore in Downtown Houston. Top attractions like Daikin Park and Toyota Center are major draws, and you can catch the metro at Central Station Main or Main Street Square Station to see more of the city.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.
Texas Medical Center
Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
