A calm lake with mountains in the background.

Find Business Hotels in Seneca, SC from CA $112

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Check availability on Seneca Business Hotels

Our top choices for Seneca business-friendly hotels

An outdoor patio area with a fire pit, seating, and string lights.

1. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (902 reviews)
"Great stay!"
United States
Melissa
The price is CA $142
CA $156 total
includes taxes & fees
Dec 12 - Dec 13
Tru by Hilton Seneca Clemson
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

2. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (767 reviews)
"Great place to stay when visiting Clemson!"
United States
Lloyd
The price is CA $169
CA $186 total
includes taxes & fees
Dec 3 - Dec 4
Hampton Inn & Suites Seneca-Clemson Area
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

3. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.2 out of 10, Wonderful, (292 reviews)
"nice,clean hotel."
United States
Steve
The price is CA $171
CA $188 total
includes taxes & fees
Nov 22 - Nov 23
Fairfield Inn & Suites Seneca Clemson Univ Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

4. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,001 reviews)
"We’ve enjoyed staying at Lakeside Lodge several times over the past few years and have always had a very pleasant experience each time! We will be staying again next time we’re in Clemson!"
United States
Karen
The price is CA $155
CA $193 total
includes taxes & fees
Nov 19 - Nov 20
Lakeside Lodge Clemson
A hotel lobby with a sofa, armchairs, a coffee station, and a reception desk.

5. Quality Inn Seneca US-123

Quality Inn Seneca US-123
2.5 star property
Seneca
8.0 out of 10, Very good, (770 reviews)
"Clean rooms clean parking area nice staff all good"
United States
Barry
The price is CA $114
CA $134 total
includes taxes & fees
Dec 1 - Dec 2
Quality Inn Seneca US-123
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

6. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (700 reviews)
"The room was clean and had no odors. But the place is seriously dated even though it was clean."
United States
Greg
The price is CA $133
CA $147 total
includes taxes & fees
Dec 1 - Dec 2
Best Western Seneca-Clemson
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

7. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (799 reviews)
"Everyone was nice and helpful and made me feel welcome"
United States
Jason
The price is CA $102
CA $112 total
includes taxes & fees
Dec 1 - Dec 2
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (120 reviews)
"Perfect location for getting away in a quiet cabin!"
United States
Lori
The price is CA $133
CA $209 total
includes taxes & fees
Dec 13 - Dec 14
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A modern bedroom with a large bed, a sofa, and a built-in wardrobe.

9. Perfect 1-bedroom hotel suites with AC in fabulous Seneca- ROOM 2

Perfect 1-bedroom hotel suites with AC in fabulous Seneca- ROOM 2
Downtown
The price is CA $205
CA $316 total
includes taxes & fees
Nov 15 - Nov 16
Perfect 1-bedroom hotel suites with AC in fabulous Seneca- ROOM 2
A fire pit with four Adirondack chairs in a grassy area surrounded by trees.

10. 8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
3.0 star property
Seneca
10.0 out of 10, Exceptional, (1 review)
"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."
United States
Jason
The price is CA $419
CA $749 total
includes taxes & fees
Nov 27 - Nov 28
8 Mi to Clemson: Peaceful Family Home w/ Yard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Frequently asked questions

How much do business-friendly hotels in Seneca cost?
You'll pay between CA $112 and CA $749 per night for business-friendly hotels in Seneca. Terrific deals on stays that are suitable for work-related travellers are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Seneca?
Seneca has multiple business-friendly hotels with a total average guest review rating of 9.9. One of the most popular is Hampton Inn & Suites Seneca-Clemson Area. Put your laptop bag down and relax at this 2.5-stars option, which includes hypo-allergenic bedding and a swimming pool. Corporate travellers also recommend Best Western Seneca-Clemson. It has a 2.5-stars rating and amenities such as a swimming pool and pool sun loungers.
How many business-friendly hotels are there in Seneca?
When your job takes you to Seneca, there are 4 business-friendly hotels to choose from. These stays combine a suitable location with the conveniences corporate travellers need.
Why book your business-friendly hotel in Seneca with Expedia?
With conveniences like meeting rooms, laundry facilities and free WiFi, our business-friendly hotels come with all you'll need to complete the job — and then chill! Enter your destination and travel dates and Expedia will help you plan the rest.
How can I find cheap business-friendly hotels in Seneca?
Click on the "business friendly" filter, listed under the "traveller experience" heading, to find cheap business-friendly hotels in Seneca. Then refine your search by your nightly budget. Looking for properties away from the city centre is another good way to save.

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