Santa Lucia Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santa Lucia vacation rentals

Townhouse in Ciampino

Plaza Rooms Ciampino
9.6 out of 10, Exceptional, (89 reviews)
"Very helpful, friendly people and pleasant area to stay. "
United Kingdom
Andrew
The price is CA $121
CA $140 total
includes taxes & fees
Mar 5 - Mar 6
Plaza Rooms Ciampino

Townhouse in Cinecitta

Camere IV Miglio
9.6 out of 10, Exceptional, (14 reviews)
"Staff was very nice and they kept and maintained the room very clean. "
United States
Jason
The price is CA $319
CA $368 total
includes taxes & fees
Mar 13 - Mar 14
Camere IV Miglio

Camping in Gianicolense Suburb

hu Roma Camping In Town
8.2 out of 10, Very good, (2,431 reviews)
"Friendly, courteous staff! Meticulous grounds, felt safe at all times! Fantastic restaurant!!"
United States
Michele
The price is CA $68
CA $85 total
includes taxes & fees
Mar 1 - Mar 2
hu Roma Camping In Town

Townhouse in Rome City Centre

Villa della Fonte - Trastevere
9.8 out of 10, Exceptional, (163 reviews)
"This is the perfect charming hotel stay if you prefer a small, quiet hotel with a helpful friendly staff, close to all the sites and culture of Rome. We couldn’t have asked for a better place to lay our heads after two magical days, especially for the price. "
United States
Leif
Villa della Fonte - Trastevere

Townhouse in Rome City Centre

Aenea Superior Inn
9.6 out of 10, Exceptional, (1,012 reviews)
"Great service, clean room, quiet, good location, walkable to many sites. Definitely will stay there again!! "
United States
Elena
The price is CA $196
CA $235 total
includes taxes & fees
Mar 3 - Mar 4
Aenea Superior Inn

Townhouse in Rome City Centre

Hanky Suite
9.6 out of 10, Exceptional, (93 reviews)
"Great location! Lovely apartment and staff very welcoming! "
United Kingdom
Jessica
The price is CA $139
CA $172 total
includes taxes & fees
Mar 5 - Mar 6
Hanky Suite

Apartment in Rome City Centre

JOIVY Cavour 238
9.2 out of 10, Wonderful, (10 reviews)
"✨ My stay at Joivys in Rome was amazing! A cozy place, great vibes, and the perfect location to enjoy the city. I felt comfortable, welcomed, and everything was spotless. Would definitely stay here again! 🇮🇹❤️ "
United States
Andres
The price is CA $141
CA $263 total
includes taxes & fees
Mar 2 - Mar 3
JOIVY Cavour 238

Townhouse in Rome City Centre

Domus Corsini
9.2 out of 10, Wonderful, (170 reviews)
"Great location. Clean, comfortable, and located in a safe area. Host was always accessible."
United States
SHAKIRA
The price is CA $197
CA $233 total
includes taxes & fees
Mar 3 - Mar 4
Domus Corsini

Townhouse in Rome City Centre

San Pietro Boutique Rooms
10.0 out of 10, Exceptional, (926 reviews)
"Great place to stay in Rome. Quiet and less crowded. "
United States
Tanya
The price is CA $236
CA $276 total
includes taxes & fees
Mar 4 - Mar 5
San Pietro Boutique Rooms

Townhouse in Ostiense

B&B di Paolo S.
9.0 out of 10, Wonderful, (131 reviews)
"It was very well kept and easy access to the city and vatican. Very clean. "
Canada
Aliasger
The price is CA $116
CA $147 total
includes taxes & fees
Mar 3 - Mar 4
B&B di Paolo S.

Aparthotel in Gianicolense

Numa Rome Trastevere
9.2 out of 10, Wonderful, (74 reviews)
"Exelente "
Mexico
ANA
The price is CA $159
CA $195 total
includes taxes & fees
Mar 5 - Mar 6
Numa Rome Trastevere

Townhouse in Rome City Centre

Relais Maddalena
9.4 out of 10, Exceptional, (816 reviews)
"Great close trevi Fountain only 5 min Walking "
Canada
Julia
The price is CA $323
CA $375 total
includes taxes & fees
Mar 2 - Mar 3
Relais Maddalena

Vacation Home in San Giovanni

Beautiful Terrace on Rome
9.8 out of 10, Exceptional, (218 reviews)
"Great place"
United States
Christopher A.
The price is CA $138
CA $231 total
includes taxes & fees
Mar 3 - Mar 4
Beautiful Terrace on Rome

Townhouse in Rome City Centre

First Floor
8.6 out of 10, Excellent, (461 reviews)
"Santins was very helpful with transportation from port to hotel as well as helping us the train arrangements, can’t thank her enough for all her help. Wonderful place to stay"
Canada
Ester
The price is CA $199
CA $239 total
includes taxes & fees
Mar 1 - Mar 2
First Floor

Townhouse in Rome City Centre

Cavour LR Collection
8.8 out of 10, Excellent, (105 reviews)
"Staff was very helpful & accommodating Perfect location to walk to the train "
United States
Mindy
The price is CA $172
CA $209 total
includes taxes & fees
Mar 15 - Mar 16
Cavour LR Collection
9.6 out of 10, Exceptional, (249 reviews)
"Gianmarco was great, very helpful .Location is close to transit .Area was safe and very walkable ."
Canada
Roger M.
The price is CA $146
CA $251 total
includes taxes & fees
Mar 2 - Mar 3
Trastevere Renovated Perfect Central Location Special offer

Townhouse in Rome City Centre

Giuditta in Trastevere
9.6 out of 10, Exceptional, (274 reviews)
"Clean room, good location and fantastic staff "
United States
alberto
Giuditta in Trastevere
9.4 out of 10, Exceptional, (281 reviews)
"Fantastic service Clean room Always fresh towels Great location"
United States
STEFAN
The Inn at the Roman Forum Luxury Collection - The Inn At The Roman Forum

Townhouse in Rome City Centre

Excellence Suite
8.6 out of 10, Excellent, (1,088 reviews)
"Staff was friendly check in was easy as well they do have shuttle service to an from the airport for a fee which is a little pricey but if u don’t want to use the train I would recommend there service not to many of them have that service, my room was nice an clean bed was absolutely comfortable too I would stay here again. "
United States
yvonne
The price is CA $139
CA $172 total
includes taxes & fees
Mar 2 - Mar 3
Excellence Suite

Townhouse in Rome City Centre

Window on Rome
9.6 out of 10, Exceptional, (296 reviews)
"Nice clean tidy place - excellent location - very friendly host"
United Kingdom
Chaim
Window on Rome
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Lucia Hotel Reviews

Find out more about Santa Lucia

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Lucia. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Santa Lucia?

Yes, there are vacation rentals near popular sights in Santa Lucia, or you can choose a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals that Santa Lucia has to offer?

Oriana Homèl Roma: This vacation home rental outside of Santa Lucia is in the city center and equipped with air-conditioning and a TV to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What’s there to see and do in Santa Lucia?

Explore the area and family-friendly sights such as Bioparco di Roma, or get out into nature at a spot like Villa Borghese. While in the area, you can also visit popular places like Spanish Steps and Trevi Fountain.

What’s a vacation rental in Santa Lucia like?

Vacation rentals are private properties where you can stay for a few weeks or just a few days in Santa Lucia. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so you'll have all the comforts of home. If you're concerned about cleanliness, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great option for families.