Title: Book the Best San Ysidro SPA Resorts from CA $206 - Spa Hotels in San Ysidro, CA | Expedia.ca [San Ysidro Travel Guide](https://expedia.ca/San-Ysidro.dx8380)[Hotels in San Ysidro](https://expedia.ca/San-Ysidro-Hotels.d8380.Travel-Guide-Hotels)[Vacation Rentals in San Ysidro](https://expedia.ca/San-Ysidro-Vacation-Rentals.d8380.Travel-Guide-VacationRentals)[Flights to San Ysidro](https://expedia.ca/Cheap-Flights-To-San-Ysidro.d8380.Travel-Guide-Flights)[Things to do in San Ysidro](https://expedia.ca/Things-To-Do-In-San-Ysidro.d8380.Travel-Guide-Activities)[San Ysidro Car Rentals](https://expedia.ca/Car-Rentals-In-San-Ysidro.d8380.Car-Rental-Guide)[San Ysidro Vacation Packages](https://expedia.ca/San-Ysidro.d8380.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/1641e603bba22aeb090af9b9cb277d0e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Mona Zambrano # Find Spa Hotels in San Ysidro, CA from CA $206 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Ysidro Spa Hotels Tonight [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-10-31&endDate=2025-11-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-11-01&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top San Ysidro Spa Hotels ![Reception](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/8496a8ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/8c14c190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/3af899ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/5c2bbbc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Island Palms Hotel & Marina Point Loma 8.8/10 Excellent (1569) "Staff were great and friendly, good food and drink, clean and good central location. " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Mick CA $179 CA $206 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Plus-Island-Palms-Hotel-Marina.h9660.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/858/c5325c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/900/858/543624c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/858/93b051f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse](https://images.trvl-media.com/lodging/1000000/10000/900/858/36c2b78d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Mission Bay Spa and Marina Mission Bay 8.4/10 Very good (1563) "The view was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $236 CA $346 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information) ![Body treatments, aromatherapy, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/b1fc21d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/2df2def5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/ed2e1ba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, ocean views ](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/06f19e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Bayfront Downtown San Diego 8.6/10 Excellent (1795) "Best hotel in San Diego!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Howie CA $188 CA $287 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/4877ef6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/1194fa32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/c517acec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/3a963240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cordova Hotel on Coronado Island Historic Downtown Coronado 8.8/10 Excellent (1004) "Cute property and easy walk to beach. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) olivia CA $196 CA $257 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Coronado-Hotels-El-Cordova-Hotel-On-Coronado-Island.h11395.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/7cb5b7d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/f0d27d94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/52554aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/cc6aac5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Humphreys Half Moon Inn Point Loma 9.2/10 Wonderful (2605) "Great views of the harbour, clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lizzie CA $208 CA $267 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Humphreys-Half-Moon-Inn.h36183.Hotel-Information) ![Facials, 2 treatment rooms, massages](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/920d9520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/ca66f35a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, white sand](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/31f9c777.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hospitality Suite, 1 King Bed, Bay View | Living room](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/d02824a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Diego Bayview Downtown San Diego 8.6/10 Excellent (1019) "The pool area was really nice and clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ana CA $189 CA $260 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-The-Westin-San-Diego-Downtown.h27516.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/d9cbfe80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2540b7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/99024d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loews Coronado Bay Resort Silver Strand 8.8/10 Excellent (1049) "The property was nice, and so was the staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) clay CA $278 CA $373 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ![Dinner served](https://images.trvl-media.com/lodging/1000000/990000/982500/982408/41f8be82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 5:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/990000/982500/982408/7806cdf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/990000/982500/982408/a9075ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/1000000/990000/982500/982408/029abbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni San Diego Hotel at the Ballpark Downtown San Diego 9.2/10 Wonderful (2053) "Professional staff, great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ryan CA $256 CA $360 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Omni-San-Diego-Hotel.h982408.Hotel-Information) ![Premier Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/fde0003f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/76794add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/6257cb78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Handlery Hotel Mission Valley 8.2/10 Very good (2193) "The hotel is very clean, pool and spa are fantastic, the food at the hotel was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eugene [](https://www.expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Couples treatment rooms, body treatments, hot stone massages](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/cba9a8a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/43ef19cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/7442075b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Legacy Resort Hotel & Spa Mission Valley 9.2/10 Wonderful (2927) "Amazing place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) daniel CA $237 CA $272 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16®ionId=8380&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top San Ysidro Hotel Reviews ![Hampton Inn & Suites by Hilton San Diego SeaWorld](//images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "Amazing " [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Best Western Seven Seas](//images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 10/10 Excellent "Nice comfy beds, beautiful property,large, good service, seperate enclosed hot tub" [](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](//images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "The staff was friendly. The rooms were clean. It had a great bar and outdoor area to relax. " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Kings Inn San Diego](//images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "All of the above" [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](//images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Balcony view and healthy breakfast! Excellent customer service!" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Bay Club Hotel & Marina](//images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Will definitely stay here again" [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "The staff were friendly. The room was clean but there were some issues in the room. Shower head was not completely sealed. There there spots on the ceiling in the bathroom and the some baseboards were messed up. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "An excellent classic beachfront hotel. We have visited the property for several years, but this is the first time that we stayed in the hotel. It lived up to all of our expectations. Located on the famous Coronado Beach, the hotel offers six different dining alternatives, each maintaining a distinctive focus and personality. Loved Nobu in particular. Nice shops. Amazing beach!!" [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "standard room, only thing we kind of have issues with was our key wasn't working properly when leaving the parking, so we would just press on the call button then they'll eventually open the gate." [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in San Ysidro? > Treat yourself to some time in a luxurious spa hotel and you won't regret it. Travelers recommend the popular shops and gourmet restaurants in San Ysidro. Enjoy the live music and beaches during your vacation. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your weekend away. ### What's there to see and do in San Ysidro? > Take in some sights and attractions while you're in San Ysidro by visiting San Ysidro Border Crossing, Las Americas Premium Outlets, and San Diego Zoo. If you have a little extra time during your trip, you might want to check out Mission Bay and Hotel del Coronado. ### What is a San Ysidro spa hotel? > Spa hotels in San Ysidro provide lodging and have an on-site spa offering services including therapies and body treatments. Some also offer in-room treatments. 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