Title: Book the Best BUSINESS Hotels in Downtown San Diego in 2025 | Expedia.ca [Downtown San Diego Travel Guide](https://expedia.ca/San-Diego-Downtown-San-Diego.dx800123)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Downtown San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-San-Diego.d800123.Car-Rental-Guide)[Downtown San Diego Vacations](https://expedia.ca/Downtown-San-Diego.d800123.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480742-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Downtown San Diego, CA from CA $244 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Downtown San Diego Business Hotels Tonight [Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=800123&startDate=2025-10-22&endDate=2025-10-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=800123&startDate=2025-10-23&endDate=2025-10-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=800123&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=800123&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Downtown San Diego Business Hotels ![3 restaurants, breakfast, lunch, dinner served; seafood](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Body treatments, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/ffc5e031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/917a1c42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/0c2ef40d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pendry San Diego Downtown San Diego 9.2/10 Wonderful (1002) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christian CA $358 CA $488 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![Presidential Suite, 2 Bedrooms, Non Smoking | Living room](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/daaed037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/aa3e65d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/b76d2e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, Bay View (Balcony) | Living room](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/0ac5494a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alma San Diego Downtown, a Tribute Portfolio Hotel Downtown San Diego 9.0/10 Wonderful (831) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Florinda CA $162 CA $244 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/San-Diego-Hotels-Alma-San-Diego-Downtown.h2133509.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24600/24548/70a722a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24600/24548/1833e214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/24600/24548/8153cf41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24600/24548/269f0284.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Westgate Hotel Downtown San Diego 9.0/10 Wonderful (1001) "Excellent hotel to stay, dinning , lobby entertainment and the gym/ pool is perfect for workout and relaxation. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa CA $247 CA $336 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/San-Diego-Hotels-Westgate-Hotel.h24548.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/e9d3f965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/8f9c8a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/de4da698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/29ee9bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Republic San Diego, Autograph Collection Downtown San Diego 9.0/10 Wonderful (1138) "Clean room and very nice staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randy CA $209 CA $283 total includes taxes & fees Nov 22 - Nov 23 [](https://www.expedia.ca/San-Diego-Hotels-Hotel-Republic-San-Diego.h898447.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, City View | View from room](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/a25502e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/46c12abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/97d1106b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/f34abdc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Vacation Club®, San Diego Downtown San Diego 9.4/10 Exceptional (1000) "The hotel is great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deon CA $213 CA $247 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/San-Diego-Hotels-Marriott-Vacation-Club-Pulse.h17865.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1120000/1117800/1117726/31af7836.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1120000/1117800/1117726/61de1a5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1120000/1117800/1117726/15b3c3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1120000/1117800/1117726/0d76e349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott Downtown San Diego 9.0/10 Wonderful (1019) "Room was great, breakfast was good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trista Theresa CA $233 CA $270 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/San-Diego-Hotels-The-Guild-Hotel.h1117726.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/w4000h2664x0y0-982a04e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/0f34ec95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/3b915004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking, Balcony](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/139a6c49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel by Marriott San Diego Downtown Gaslamp Quarter Downtown San Diego 8.8/10 Excellent (940) "Amazing hotel and amazing staff at the front desk and bar " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert B CA $233 CA $270 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/San-Diego-Hotels-AC-Hotel-By-Marriott-San-Diego-Downtown-Gaslamp-Quarter.h87137975.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/e71c0bc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/d6c34b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/10ea342c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/61ab8b94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The US Grant, a Luxury Collection Hotel, San Diego Downtown San Diego 9.0/10 Wonderful (1003) "The staff was excellent and attentive. It was centrally located to all we wished to visit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $368 CA $427 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-THE-US-GRANT.h10802.Hotel-Information) ![60-inch flat-screen TV with cable channels, TV, pay movies](https://images.trvl-media.com/lodging/1000000/480000/477000/476989/915cb89b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/480000/477000/476989/6612b3ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | Living area](https://images.trvl-media.com/lodging/1000000/480000/477000/476989/651eee83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/477000/476989/w3837h2557x3y3-fb76a9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Gaslamp Quarter Downtown San Diego 9.0/10 Wonderful (217) "Hotel is conveniently located. Hotel is clean and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darleen CA $240 CA $339 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Gaslamp-Quarter.h476989.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/330000/327500/327441/338bb608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327500/327441/77c0542b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/330000/327500/327441/27f733a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking (View)](https://images.trvl-media.com/lodging/1000000/330000/327500/327441/dfc0f891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Downtown Downtown San Diego 8.8/10 Excellent (1000) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda CA $227 CA $263 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Downtown.h327441.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-05&endDate=2025-11-06®ionId=800123&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Price trends for hotels in Downtown San Diego | Less expensive | More expensive | Next month | | --- | --- | --- | | December | July | CA $260 | | Month | Price | | --- | --- | | January | CA $280 | | February | CA $343 | | March | CA $340 | | April | CA $399 | | May | CA $396 | | June | CA $450 | | July | CA $487 | | August | CA $429 | | September | CA $467 | | October | CA $235 | | November | CA $260 | | December | CA $215 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Downtown San Diego. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Top Downtown San Diego Hotel Reviews ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Older property but great location. Friendly staff and lots nearby. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](//images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Amazing staff! From front desk to dinning and bar area! Safe area, walking distance to restaurants " [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter](//images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a0a6825c_y.jpg) ### Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter 10/10 Excellent "It was a very nice place to stay at! The people were welcoming and the environment was clean! It was a great experience to stay at, thank you. " [](https://expedia.ca/San-Diego-Hotels-Residence-Inn-By-Marriott-San-Diego-DowntownGaslamp-Quarter.h2918129.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "The only negative is you have to pay for parking daily $35 and a fee " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![The Horton Grand, Downtown/Gaslamp Quarter](//images.trvl-media.com/lodging/1000000/20000/11100/11026/ce3fee83_y.jpg) ### The Horton Grand, Downtown/Gaslamp Quarter 10/10 Excellent "Such a beautiful hotel. So much history, if you stay here, make sure you read about their history on the website. We chose this place for a last minute one night, romantic getaway. It did not disappoint. We were able to walk to Seaport Village and to the Gaslamp district. Everything was so close." [](https://expedia.ca/San-Diego-Hotels-The-Horton-Grand.h11026.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "The hotel is beautiful and conveniently located near Seaport Village, offering everything you need within walking distance. You and your family can fully enjoy your stay without having to venture far—Seaport Village and the hotel itself provide plenty to experience. The dining options are both affordable and excellent. There is truly no better hotel to choose from." [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Clean rooms, great staf, convenient to restaurant's, ferry to coronado island and train system " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Marriott Marquis San Diego Marina](//images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee_y.jpg) ### Marriott Marquis San Diego Marina 10/10 Excellent "Amazing view- absolutely beautiful property. Worth the stay." [](https://expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) ![Holiday Inn Express San Diego Downtown by IHG](//images.trvl-media.com/lodging/1000000/50000/40700/40681/a459623d_y.jpg) ### Holiday Inn Express San Diego Downtown by IHG 10/10 Excellent "Clean corner room, great breakfast, safe and affordable " [](https://expedia.ca/San-Diego-Hotels-Holiday-Inn-Express-San-Diego-Downtown.h40681.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in Downtown San Diego with Expedia? > Expedia is here to help you find a fantastic business-friendly hotel when work takes you out of town. From free parking and WiFi to on-site restaurants and cafés, our stays come with all you'll need to settle that big contract. ### How can I find cheap business-friendly hotels in Downtown San Diego? > Expedia can help you easily find cheap business-friendly hotels in Downtown San Diego. Head to our "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work and rest comfortably, like free WiFi and included breakfast. 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