Title: Hotels by La Quinta Inn & Suites in Roxana from CA $79 | Expedia.ca [Roxana Travel Guide](https://expedia.ca/Roxana.dx3000346551)[Hotels in Roxana](https://expedia.ca/Roxana-Hotels.d3000346551.Travel-Guide-Hotels)[Vacation Rentals in Roxana](https://expedia.ca/Roxana-Vacation-Rentals.d3000346551.Travel-Guide-VacationRentals)[Flights to Roxana](https://expedia.ca/Cheap-Flights-To-Roxana.d3000346551.Travel-Guide-Flights)[Roxana Car Rentals](https://expedia.ca/Car-Rentals-In-Roxana.d3000346551.Car-Rental-Guide)[Roxana Vacation Packages](https://expedia.ca/Roxana.d3000346551.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in Roxana from CA $79 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 24 - Dec 25](https://www.expedia.ca/Hotel-Search?regionId=3000346551&startDate=2025-12-24&endDate=2025-12-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 25 - Dec 26](https://www.expedia.ca/Hotel-Search?regionId=3000346551&startDate=2025-12-25&endDate=2025-12-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=3000346551&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=3000346551&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Roxana La Quinta Inn & Suites ![Deluxe Room, 1 King Bed, Non Smoking (Deluxe Executive Room)](https://images.trvl-media.com/lodging/1000000/50000/40200/40129/ea762edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/40200/40129/9141e4c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40129/2f819757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40129/ee0978d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North [](https://www.expedia.ca/St-Louis-Hotels-La-Quinta-Inn-By-Wyndham-St-Louis-Hazelwood-Airport-North.h40129.Hotel-Information) Hazelwood 6.6/10 (1007) "Staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Courtney CA $84 CA $102 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/St-Louis-Hotels-La-Quinta-Inn-By-Wyndham-St-Louis-Hazelwood-Airport-North.h40129.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/77e26325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/67c9e775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/2d66b8eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/e7762532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Collinsville - St. Louis [](https://www.expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Collinsville-St-Louis.h9642754.Hotel-Information) Eastport 7.2/10 Good (1004) "Everything was nice and clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Avanjanae CA $113 CA $130 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Collinsville-St-Louis.h9642754.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/c5041840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/1a232cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/a9eaceec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/079daa32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis [](https://www.expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OFallon.h201286.Hotel-Information) O'Fallon 6.0/10 (1000) "Clean bed and room. Very nice staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nita CA $69 CA $79 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OFallon.h201286.Hotel-Information) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/dfd22323.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking (Mobility Accessible)](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/7068f006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/f969f8e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/9075cfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Pontoon Beach [](https://www.expedia.ca/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Pontoon-Beach.h424254.Hotel-Information) Granite City 7.6/10 Good (514) "The hotel staff was exceptionally accommodating. Would stay here over anywhere in the area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kari CA $119 CA $137 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Pontoon-Beach.h424254.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-07&endDate=2026-01-08®ionId=3000346551&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FRoxana-Hotels-La-Quinta-Inn-Suites.0-0-d3000346551--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FRoxana-Hotels-La-Quinta-Inn-Suites.0-0-d3000346551--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Roxana Hotel Reviews ![Pear Tree Inn St. Louis Near Union Station](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/0bb9dbf3_y.jpg) ### Pear Tree Inn St. Louis Near Union Station 10/10 Excellent "Yes, very friendly staff, clean room " [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Near-Union-Station.h26572.Hotel-Information) ![Drury Inn & Suites St. Louis Union Station](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4_y.jpg) ### Drury Inn & Suites St. Louis Union Station 10/10 Excellent "Great stay Drury is always on point" [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e_y.jpg) ### Hyatt Regency St. Louis at The Arch 10/10 Excellent "The staff were incredible!! Jeremiah in guest services is an absolute gem! " [](https://expedia.ca/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Home2 Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510729/104b5741_y.jpg) ### Home2 Suites by Hilton St. Louis Downtown 10/10 Excellent "Great stay which is consistent for the Home 2 Suites. " [](https://expedia.ca/St-Louis-Hotels-Home2-Suites-St-Louis-Downtown.h76510729.Hotel-Information) ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 10/10 Excellent "The room was ever nice and comfortable. The hotel was was very beautiful and staff was very nice and friendly. Will definitely stay again" [](https://expedia.ca/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton 10/10 Excellent "In addition to being very near the Fox Theatre, the concept of the property was appealing during my search. My wife and i absolutely loved everything about this property: decor, the penthouse art lounge, the food and most importantly, the service and friendliness from ALL staff members! We will definitely stay here again on our next visit." [](https://expedia.ca/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) ![Live by Loews - St.Louis](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/4c39e93f_y.jpg) ### Live by Loews - St.Louis 10/10 Excellent "Clean room, great restaurant and bar down stairs " [](https://expedia.ca/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758_y.jpg) ### 21C Museum Hotel St Louis 10/10 Excellent "Clean room, nice linens, great view!" [](https://expedia.ca/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![Hampton Inn St. Louis-Downtown (At the Gateway Arch)](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/w3837h2560x0y0-a6354f1b_y.jpg) ### Hampton Inn St. Louis-Downtown (At the Gateway Arch) 10/10 Excellent "Staff was so nice and helpful." 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