Roxana Vacation Packages

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Your Roxana Vacation

Let our vacation packages to Roxana inspire your next escape. There's tons to love about this exciting city, starting with the neighborhood of Old Jamestown, which is great for nature and walking. Fill your free time with tours of Fast Eddies Bon Air, Robert Wadlow Statue and Lewis and Clark Interpretive Center, some of the top attractions you should see during your trip to Roxana. Your dream Roxana vacation is a few clicks away. Search hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.

Top Roxana Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
Price was CA $1,150, price is now CA $1,046 per person
CA $1,046
per person
Sep 7 - Sep 14
found 21 hours ago
Roundtrip flight included
Montreal (YUL) to St. Louis (STL)
7.4/10 Good! (170 reviews)
Swimming pool is nice and large. Great for kids after a long day in the car.

Reviewed on Jul 3, 2026

Garden House Bed and Breakfast

Garden House Bed and Breakfast

2 out of 5
Price was CA $1,452, price is now CA $1,277 per person
CA $1,277
per person
Sep 7 - Sep 14
found 21 hours ago
Roundtrip flight included
Montreal (YUL) to St. Louis (STL)
8.4/10 Very good! (43 reviews)
Chris absolutely made our stay!!!! A great place, wonderful host, breakfast was great. If we go to Hannibal again, this is absolutely the place we will stay!!!!

Reviewed on Jun 22, 2026

Best Western On The River

Best Western On The River

2.5 out of 5
Price was CA $1,557, price is now CA $1,371 per person
CA $1,371
per person
Sep 7 - Sep 14
found 21 hours ago
Roundtrip flight included
Montreal (YUL) to St. Louis (STL)
8.6/10 Excellent! (1,011 reviews)
It was okay but really needs updating. The beds are awful. Lobby was nice . I would not stand again because $255 is to expensive

Reviewed on Jul 4, 2026

Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
Price was CA $1,945, price is now CA $1,739 per person
CA $1,739
per person
Sep 7 - Sep 14
found 21 hours ago
Roundtrip flight included
Montreal (YUL) to St. Louis (STL)
9/10 Wonderful! (30 reviews)
The owners have really outdone themselves with the remodel of this motel! They went above and beyond for our stay for our anniversary and are the nicest people. We will definitely stay again!

Reviewed on Jun 29, 2026

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
Price was CA $1,246, price is now CA $1,117 per person
CA $1,117
per person
Sep 7 - Sep 14
found 21 hours ago
Roundtrip flight included
Montreal (YUL) to St. Louis (STL)
7.4/10 Good! (1,007 reviews)
Noisy above the room

Reviewed on Jul 4, 2026

Ready to book your vacation to Roxana?

 

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Roxana Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $234 per night from Jul 17 to Jul 18
CA $234
CA $276 total
Jul 17 - Jul 18
includes taxes & fees
8.6/10 Excellent! (4,178 reviews)
"All good"

Reviewed on Jul 5, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $134 per night from Jul 12 to Jul 13
CA $134
CA $156 total
Jul 12 - Jul 13
includes taxes & fees
9/10 Wonderful! (3,266 reviews)
"Really enjoyed our stay. We would like to come back...."

Reviewed on Jul 5, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is CA $128 per night from Aug 2 to Aug 3
CA $128
CA $150 total
Aug 2 - Aug 3
includes taxes & fees
9.2/10 Wonderful! (3,065 reviews)
"Good and clean rooms"

Reviewed on Jul 5, 2026

Pear Tree Inn St. Louis Airport
See all 1,508 properties in Roxana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Stay near popular Roxana attractions

Wood River Refinery History Museum

You can spend an afternoon studying the exhibits at Wood River Refinery History Museum in Roxana.
See properties

Frequently asked questions

How much does a Roxana vacation package cost?
You'll find cheap prices from CA $1,046 on Expedia for your Roxana break. However, factors like the hotel choice, length of stay and season will determine how much your vacation to Roxana costs.
What are the cheapest months to go to Roxana?
January, February and November are great times to look for cheap Roxana vacation packages. Choosing to travel in less busy months means you'll typically find reduced prices on accommodations and flights.
How many days is enough for Roxana?
For your Roxana vacation, a few days will be enough to see all the highlights. Make sure to check out National Great Rivers Museum — it's one of the leading sights in this destination. If you're looking for more activities, think about basing yourself here and venturing off on some tours from Roxana.
How to find the best Roxana package deals?
Landing a cheap Roxana package deal is easy with Expedia. After you've entered your trip dates and destination under our "Packages" tab, set your budget, apply a few filters and browse what's available. You can fine-tune your search by "Amenities," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most pocket-friendly Roxana package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider travelling on a weekday, when prices are typically lower.
Is it cheaper to book a Roxana vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to booking flights and stays separately. Better still, you can personalize your Roxana getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Roxana?
If you have your Roxana vacation dates finalized, book as soon as you can to bag some terrific deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are perfect for travelling on a whim.
How to plan a trip to Roxana?

  1. Choose the best time to travel: Your schedule, favourite season and the type of weather you enjoy can all influence your decision on when to travel to Roxana.
  2. Calculate your budget: Make sure you have enough money to pay for everything from transportation and food to activities and airfares. Your accommodations will probably be the biggest expense during your trip to Roxana.
  3. Decide your trip length: Consider how much time you'd like to spend exploring Roxana. Plan your itinerary so you can get to all the activities and attractions you're interested in without rushing.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a personalized Roxana vacation package.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.