Title: Hotels by La Quinta Inn & Suites in Port Isabel from CA $192 | Expedia.ca [Port Isabel Travel Guide](https://expedia.ca/Port-Isabel.dx184007)[Hotels in Port Isabel](https://expedia.ca/Port-Isabel-Hotels.d184007.Travel-Guide-Hotels)[Vacation Rentals in Port Isabel](https://expedia.ca/Port-Isabel-Vacation-Rentals.d184007.Travel-Guide-VacationRentals)[Flights to Port Isabel](https://expedia.ca/Cheap-Flights-To-Port-Isabel.d184007.Travel-Guide-Flights)[Things to do in Port Isabel](https://expedia.ca/Things-To-Do-In-Port-Isabel.d184007.Travel-Guide-Activities)[Port Isabel Car Rentals](https://expedia.ca/Car-Rentals-In-Port-Isabel.d184007.Car-Rental-Guide)[Port Isabel Vacation Packages](https://expedia.ca/Port-Isabel.d184007.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/6eb3b856eb8d266fbe19de2b663e7a1b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in Port Isabel from CA $192 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 17 - Nov 18](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-11-17&endDate=2025-11-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 18 - Nov 19](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-11-18&endDate=2025-11-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Port Isabel La Quinta Inn & Suites Hotels ![Gazebo](https://images.trvl-media.com/lodging/1000000/990000/987100/987074/a90911d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/987100/987074/8bba8b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/990000/987100/987074/40f6def8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/990000/987100/987074/935cdcdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Brownsville North Brownsville 8.6/10 Excellent (1000) "Expedia did everything took care of everything.When we got to hotel at the counter they had everything for us.Was very clean so comfortable.Best pillows ever.We want to stay one more night." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Biby CA $167 CA $192 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Brownsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Brownsville-North.h987074.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-02&endDate=2025-12-03®ionId=184007&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPort-Isabel-Hotels-La-Quinta-Inn-Suites.0-0-d184007--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPort-Isabel-Hotels-La-Quinta-Inn-Suites.0-0-d184007--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Port Isabel Hotel Reviews ![Isla Grand Beach Resort](//images.trvl-media.com/lodging/1000000/10000/9100/9005/ea4039fe_y.jpg) ### Isla Grand Beach Resort 10/10 Excellent "Good " [](https://expedia.ca/South-Padre-Island-Hotels-Isla-Grand-Beach-Resort.h9005.Hotel-Information) ### La Copa Inn Beach Hotel 10/10 Excellent "Great place " [](https://expedia.ca/South-Padre-Island-Hotels-La-Copa-Inn-Beach-Hotel.h1091955.Hotel-Information) ### Sand Rose Beach Resort 10/10 Excellent "It was clean and staff was courteous. " [](https://expedia.ca/South-Padre-Island-Hotels-Sand-Rose-Beach-Resort.h97048597.Hotel-Information) ### Holiday Inn Express Hotel & Suites South Padre Island by IHG 10/10 Excellent "Yes room was nice and clean. Staff was great! Short walk to the beach Good breakfast buffet. We really enjoyed ourselves Will definitely be back " [](https://expedia.ca/South-Padre-Island-Hotels-Holiday-Inn-Express-Hotel-Suites-South-Padre-Island.h1194363.Hotel-Information) ### Best Western Beachside Inn 10/10 Excellent "Friendliness of Staff." [](https://expedia.ca/South-Padre-Island-Hotels-Best-Western-Beachside-Inn.h797201.Hotel-Information) ### Margaritaville Beach Resort South Padre Island 10/10 Excellent "Everything was good and decent especially when you have good state troopers around making sure everything is good and in order. The vent in the bathrooms doesn’t appear to be working and breakfast prices were a bit high. Other than that everything was great." [](https://expedia.ca/South-Padre-Island-Hotels-Pearl-South-Padre.h21996.Hotel-Information) ### El Delfín Lodge 10/10 Excellent "Receptionist was very nice. We showed up early and he offered to call us when the room was ready, which he did. Had a few perishables from the trip and he allowed us to store them temporarily in the fridge until the room was ready." [](https://expedia.ca/South-Padre-Island-Hotels-El-Delfin-Lodge.h76149536.Hotel-Information) ![Hilton Garden Inn South Padre Island Beachfront](//images.trvl-media.com/lodging/4000000/3510000/3508900/3508863/a7c9c9bc_y.jpg) ### Hilton Garden Inn South Padre Island Beachfront 10/10 Excellent "The property was pet friendly." [](https://expedia.ca/South-Padre-Island-Hotels-Hilton-Garden-Inn-South-Padre-Island-Beachfront.h3508863.Hotel-Information) ### Holiday Inn Resort South Padre Island - Beach Front by IHG 10/10 Excellent "Nice area, loved the heated pool, close to everything. 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