
Pickens County Vacation Packages
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Your Pickens County Vacation
Make planning your next big adventure quick and easy with a Pickens County vacation package. Whether it's the cuisine, nature or something else that draws you to this destination, our packages will help you experience it all. Start your trip to Pickens County with a couple of days in Clemson visiting popular sights like Memorial Stadium and South Carolina Botanical Gardens. Powdersville is another top city that lures travellers from near and far. Falls Park on the Reedy and Bon Secours Wellness Arena are two of the top places to see here. Expedia has hotels, flights, car rentals and more to help you create your own customized Pickens County vacation today.
Top vacation destinations in Pickens County

Central
Pickens County Hotel Deals

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
The price is CA $135 per night from Jul 21 to Jul 22
CA $135
CA $150 total
Jul 21 - Jul 22
includes taxes & fees
8.2/10 Very good! (1,010 reviews)
"Everyone was very accommodating. I wish the dog space was a little larger but everything met my needs."
Reviewed on Jul 9, 2026

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
The price is CA $198 per night from Jul 13 to Jul 14
CA $198
CA $220 total
Jul 13 - Jul 14
includes taxes & fees
9.8/10 Exceptional! (838 reviews)
"Loved everything about this hotel . Stay away from the Inn at Clemson !"
Reviewed on Jul 9, 2026

Inn @ Clemson
1303 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
The price is CA $104 per night from Jul 13 to Jul 14
CA $104
CA $116 total
Jul 13 - Jul 14
includes taxes & fees
8/10 Very good! (1,004 reviews)
"Clean and comfortable stay."
Reviewed on Jul 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Stay near popular Pickens County attractions
What to do in Pickens County

Paranormal Walking Tour by Greenville Ghost Tours
CA $50
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.













