Pickens County Vacation Packages

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Your Pickens County Vacation

Make planning your next big adventure quick and easy with a Pickens County vacation package. Whether it's the cuisine, nature or something else that draws you to this destination, our packages will help you experience it all. Start your trip to Pickens County with a couple of days in Clemson visiting popular sights like Memorial Stadium and South Carolina Botanical Gardens. Powdersville is another top city that lures travellers from near and far. Falls Park on the Reedy and Bon Secours Wellness Arena are two of the top places to see here. Expedia has hotels, flights, car rentals and more to help you create your own customized Pickens County vacation today.

Top vacation destinations in Pickens County

Todd Creek Falls
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Central

Central

Pickens County Hotel Deals

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
The price is CA $146 per night from Apr 22 to Apr 23
CA $146
CA $162 total
Apr 22 - Apr 23
includes taxes & fees
8.2/10 Very Good! (1,001 reviews)
standard hotel and amenities, all that was needed

Reviewed on Apr 8, 2026

Best Western Plus Clemson Hotel & Conference Center
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
The price is CA $276 per night from Apr 14 to Apr 15
CA $276
CA $306 total
Apr 14 - Apr 15
includes taxes & fees
9.8/10 Exceptional! (783 reviews)
hotel was great, modern, clean gorgeous

Reviewed on Apr 7, 2026

The Shepherd Hotel Downtown Clemson
The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
115 Market Street Clemson SC
The price is CA $220 per night from Apr 12 to Apr 13
CA $220
CA $244 total
Apr 12 - Apr 13
includes taxes & fees
9.8/10 Exceptional! (827 reviews)
Very nice hotel - very clean, beautiful decor.

Reviewed on Apr 9, 2026

The Inn at Patrick Square
See all 5,240 properties in Pickens County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Beach Vacations
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Family Vacations

Frequently asked questions

How much does a Pickens County vacation package cost?
Custom make your Pickens County vacation package from only . Pick from any combination of hotels, flights and rental cars to put together the trip you've been dreaming about for ages. Remember to add on a few experiences or tours!
How do I get a cheap travel package to Pickens County?
If you love getting an amazing deal, bundle your bookings into a Pickens County vacation package. Whether you're looking for flights, hotels, day tours or rental cars, you can book everything in one place. You'll have a wealth of choice at your fingertips too. Expedia has more than 550 airlines and 1,000,000 hotels across the globe to take your pick of. Fly with who you want, stay where you like and save some cash — now that's the perfect getaway!
What are the top hotels in Pickens County?
When it comes to hotels in Clemson, Comfort Inn & Suites Clemson - University Area and Inn @ Clemson are two excellent options. If you're visiting Easley, Best Western Greenville Airport Inn and La Quinta Inn & Suites by Wyndham Greenville Haywood look forward to welcoming you.
How far in advance should I book my Pickens County vacation?
To bag discount prices, book as early as you can. Airlines typically release flights, along with some of the lowest fares, nearly a year in advance. Hotels, car rental and experiences should also be booked early to avoid disappointment. If you've decided on a last-minute getaway in Pickens County, there are always plenty of great deals on Expedia. Book your escape today!
What does an Expedia Pickens County travel package include?
That depends on what you're looking for. If you're traveling by yourself, you might decide to bundle flights and hotels. Bringing the entire family to Pickens County? A travel package that includes flights, hotels and rental cars might suit you better. Expedia gives you the flexibility and freedom to tailor your travel package.
What should I know before booking a Pickens County travel package?
When you book your hotels, flights and car rentals together, you'll score great discounts. Whether you're planning a rural escape in a cottage or want to stay in a luxurious city hotel, Expedia will make it happen for less.
Can I choose my airline with a Pickens County Expedia vacation package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Search the available options and find out which airline suits your budget and needs.
If I'm not able to travel, can I cancel my Pickens County vacation package?
Don't stress if you're rethinking your Pickens County vacation package — it's possible to change or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We understand your circumstances can suddenly change, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.