Title: Pickens County Vacation Rentals from CA $152: Short-Term Rentals for 2026 | Expedia.ca [Pickens County Hotels](https://expedia.ca/Destinations-In-Pickens-County.d553248635083907325.Hotel-Destinations)[Pickens County Car Rentals](https://expedia.ca/Destinations-In-Pickens-County.d553248635083907325.Car-Rental-Destinations)[Pickens County Vacations](https://expedia.ca/Pickens-County.d553248635083907325.Destination-Travel-Guides) ![A great spot for sunsets! For a video guide of this destination, please visit: https://www.hdcarolina.com/episode/sassafras-mountain](https://images.trvl-media.com/place/6348031/3bb247cb-6423-45f6-a6a6-840c399ca45c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts ![](https://images.trvl-media.com/place/6348031/3bb247cb-6423-45f6-a6a6-840c399ca45c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Pickens County ![](https://mediaim.expedia.com/destination/1/37a5b84dadafa74cfb0eac38a6f52509.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Clemson [](https://expedia.ca/Clemson-Vacation-Rentals.d6594.Travel-Guide-VacationRentals) ## Our top choices for Pickens County vacation rentals ![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/afe0f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Courtyard View | Front of property](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/f825207a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/b26b87ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Courtyard View | Living area](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/3f2de599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carolina Camp Cedar [](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) Pickens 10/10 Exceptional (1 review) "This place was super clean and super cute! Convenient to everything I needed. I enjoyed the quietness." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $129 CA $265 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/de87b393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/1a9df087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/394f1525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/77000000/76930000/76929000/76928997/w945h710x0y32-a770d4e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lazy Bear Retreat by the Creek [](https://www.expedia.ca/Pickens-Hotels-Lazy-Bear-Retreat-By-The-Creek.h76928997.Hotel-Information) Pickens 10/10 Exceptional (49 reviews) "What a beautiful little getaway! Great communication with owner, easy to find the location and entry. Everything was very clean and working as it should. Loved the hot tub." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Molly CA $117 CA $251 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Pickens-Hotels-Lazy-Bear-Retreat-By-The-Creek.h76928997.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/efec02d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/69fcdbfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/fc94d8c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, table tennis](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/ad2b1b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Vacation Mountain Home [](https://www.expedia.ca/Pickens-Hotels-Luxury-Vacation-Mtn-Home.h66026894.Hotel-Information) Pickens 9.8/10 Exceptional (25 reviews) "Everything was perfect from the hot tub to the comfort of the beds!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly C. CA $154 CA $453 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Pickens-Hotels-Luxury-Vacation-Mtn-Home.h66026894.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/23000000/22130000/22120400/22120360/w799h599x1y1-a20a5639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22130000/22120400/22120360/83b0dc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player](https://images.trvl-media.com/lodging/23000000/22130000/22120400/22120360/w3200h1537x0y0-2c240375.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22130000/22120400/22120360/72ad9aac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peace-in-the-Forest Retreat - Singles, Couples, Artists, Forest Lovers [](https://www.expedia.ca/Pickens-Hotels-Peace-In-The-Forest-Retreat-Singles.h22120360.Hotel-Information) Pickens 10/10 Exceptional (276 reviews) "We really enjoyed our stay. Close to town, easy to get around." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angie E. CA $123 CA $275 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Pickens-Hotels-Peace-In-The-Forest-Retreat-Singles.h22120360.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/108000000/107780000/107773400/107773310/7a59f7da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/108000000/107780000/107773400/107773310/74e49b03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107780000/107773400/107773310/c6cccc88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/108000000/107780000/107773400/107773310/2d362c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Romantic Cottage Getaway, tucked peacefully in the woods [](https://www.expedia.ca/Pickens-Hotels-Romantic-Cottage-Getaway.h107773310.Hotel-Information) Pickens 10/10 Exceptional (16 reviews) "Amazing secluded retreat!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen N. CA $220 CA $277 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Pickens-Hotels-Romantic-Cottage-Getaway.h107773310.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/83fe6802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/f5e918bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/7c7b67a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/94af1b49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gnome Hill Cottage - A Rustic Pet-Friendly Cottage In The Woods [](https://www.expedia.ca/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) Cleveland 9.8/10 Exceptional (109 reviews) "We absolutely loved our stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla R. CA $150 CA $197 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) ![Signature Cottage, 2 Bedrooms | Living room](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/a4df93b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/b86441f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/9cd5859a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | Private kitchen](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/0d77f138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson Memorabilia House [](https://www.expedia.ca/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information) Clemson 9.8/10 Exceptional (9 reviews) "We enjoyed our stay, it was the perfect size for our family of four. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley CA $122 CA $325 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/8dd3309b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/0ab2e017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/56576d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/bf825374.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Apple Cottage [](https://www.expedia.ca/Pickens-Hotels-Country-Apple-Cottage.h103157886.Hotel-Information) Pickens 10/10 Exceptional (32 reviews) "Great place close to Clemson. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos V. CA $110 CA $228 total includes taxes & fees Mar 4 - Mar 5 [](https://www.expedia.ca/Pickens-Hotels-Country-Apple-Cottage.h103157886.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/0fa322d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/fcc5512f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/66271ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, travel crib, WiFi](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/6ea9c430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ballgame Bungalow, Entire 2BR/2BA Apt in Clemson [](https://www.expedia.ca/Clemson-Hotels-Ballgame-Bungalow.h99942155.Hotel-Information) Clemson 9.2/10 Wonderful (9 reviews) "We had a great stay in this clean and centrally located two bedroom place - including quick communication with the property managers when we had some problems with the WiFi! Loved the location, will absolutely visit again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Agatha L. CA $152 CA $485 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Clemson-Hotels-Ballgame-Bungalow.h99942155.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/104000000/103370000/103361200/103361112/22dee56f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103370000/103361200/103361112/4e0f5deb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103370000/103361200/103361112/a9077bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103370000/103361200/103361112/278c31c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mountains-Lakes-Parks-Winery-Privacy-Serenity Leaf Peeping Paradise [](https://www.expedia.ca/Cleveland-Hotels-Cabin-5-Min-To-Table-Rock-State-Park-SC-2b2b-Wfin-Basement-In-Blue-Ridge-Mnts.h103361112.Hotel-Information) Cleveland 10/10 Exceptional (15 reviews) "Amazing stay 10/10 will definitely be back." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Justacoupleofbroskis CA $197 CA $480 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Cleveland-Hotels-Cabin-5-Min-To-Table-Rock-State-Park-SC-2b2b-Wfin-Basement-In-Blue-Ridge-Mnts.h103361112.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/b7a1f289.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/830174bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/7411cba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, foosball, books](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/d57b249b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Welcome To Downtown Pickens close to Clemson and Lake Keowee [](https://www.expedia.ca/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information) Pickens 9.8/10 Exceptional (31 reviews) "Great location, close to great restaurants and downtown. Beautiful area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom B. CA $148 CA $360 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35600000/35592200/35592109/039950d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/36000000/35600000/35592200/35592109/622086bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/36000000/35600000/35592200/35592109/16a0fe2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/36000000/35600000/35592200/35592109/81607464.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson Lover's Dream Cottage [](https://www.expedia.ca/Anderson-Hotels-Tiger-Lovers-Dream-Cottage.h35592109.Hotel-Information) Clemson 10/10 Exceptional (64 reviews) "The cottage was above our expectations, just as advertised and better!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Katherine Z. CA $308 CA $443 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Anderson-Hotels-Tiger-Lovers-Dream-Cottage.h35592109.Hotel-Information) ![Dining tables](https://images.trvl-media.com/lodging/92000000/91920000/91913000/91912972/73f5a22e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/92000000/91920000/91913000/91912972/944134be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, shampoo](https://images.trvl-media.com/lodging/92000000/91920000/91913000/91912972/9fa6aed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91920000/91913000/91912972/8b3a0cd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish Studio Loft Apartment with cool mid-century vibes [](https://www.expedia.ca/Pickens-Hotels-Stylish-Studio-Loft-Apartment-With-Cool-Mid-Century-Vibes.h91912972.Hotel-Information) Pickens 10/10 Exceptional (7 reviews) "Super cute property and host was very nice. Plan on staying here any time I visit my sister. One of the best we’ve stayed at by far. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Holly B. CA $239 CA $405 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Pickens-Hotels-Stylish-Studio-Loft-Apartment-With-Cool-Mid-Century-Vibes.h91912972.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/124000000/123080000/123079900/123079862/64855080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123080000/123079900/123079862/8ec136fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/124000000/123080000/123079900/123079862/2f3ce45f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/124000000/123080000/123079900/123079862/fd742f6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riverfront Cabin Retreat w/ Hot Tub! Blue Heron [](https://www.expedia.ca/Easley-Hotels-Riverfront-Cabin-Retreat-W-Hot-Tub-Blue-Heron.h123079862.Hotel-Information) Easley 10/10 Exceptional (1 review) "Loved the host & amenities. Quiet and serene. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) April and Julien P. [](https://www.expedia.ca/Easley-Hotels-Riverfront-Cabin-Retreat-W-Hot-Tub-Blue-Heron.h123079862.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/0e18a612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/7923d847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/87fa1a3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/33804100.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Black Bear Hideaway [](https://www.expedia.ca/Pickens-Hotels-Black-Bear-Hideaway.h120648317.Hotel-Information) Pickens 9.6/10 Exceptional (4 reviews) "Great location to hiking trails." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeromy S. CA $123 CA $327 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Pickens-Hotels-Black-Bear-Hideaway.h120648317.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/90000000/89680000/89679000/89678964/82cce3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89680000/89679000/89678964/943398f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi](https://images.trvl-media.com/lodging/90000000/89680000/89679000/89678964/f826e74c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/90000000/89680000/89679000/89678964/f0cde57a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TigerTown Retreat - Comfort Minutes from Campus [](https://www.expedia.ca/Central-Hotels-3br-APT-Perfect-Location-Clemson-Games-Visits.h89678964.Hotel-Information) Central 10/10 Exceptional (13 reviews) "Property was as described and having an awesome Mexican Restaurant right next door was a definite plus! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet S. CA $178 CA $399 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Central-Hotels-3br-APT-Perfect-Location-Clemson-Games-Visits.h89678964.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/90000000/89510000/89505000/89504913/8b116785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89510000/89505000/89504913/w834h995x3y0-be130cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89510000/89505000/89504913/765d396e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/90000000/89510000/89505000/89504913/3f8a1f50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson Memorabilia House Frank Howard III’s Home [](https://www.expedia.ca/Clemson-Hotels-Clemson-Memorabilia-House-Frank-Howard-IIIs-Home.h89504913.Hotel-Information) Clemson 8.6/10 Excellent (17 reviews) "The house was really cute and very clean. The host was Amaya extremely responsive. Thank you!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) juan m. CA $115 CA $361 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Clemson-Hotels-Clemson-Memorabilia-House-Frank-Howard-IIIs-Home.h89504913.Hotel-Information) ![TV, fireplace, books](https://images.trvl-media.com/lodging/71000000/70950000/70943300/70943253/06f40529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/71000000/70950000/70943300/70943253/1131e813.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, books](https://images.trvl-media.com/lodging/71000000/70950000/70943300/70943253/310ad29d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/71000000/70950000/70943300/70943253/73abdc40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Happy Trails: Jacuzzi, Lookout Tower, Views! [](https://www.expedia.ca/Pickens-Hotels-Happy-Trails-Jacuzzi.h70943253.Hotel-Information) Pickens 10/10 Exceptional (4 reviews) "Great stay at this beautiful home!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan E. CA $209 CA $934 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Pickens-Hotels-Happy-Trails-Jacuzzi.h70943253.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/123000000/122110000/122105200/122105164/4442828c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122110000/122105200/122105164/40f570e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/123000000/122110000/122105200/122105164/42239cc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/123000000/122110000/122105200/122105164/2bcbdb10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Contemporary Hideout | 7min to Clemson University [](https://www.expedia.ca/Central-Hotels-Contemporary-Hideout-7min-To-Clemson-University.h122105164.Hotel-Information) Central CA $183 CA $472 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Central-Hotels-Contemporary-Hideout-7min-To-Clemson-University.h122105164.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119930000/119922300/119922213/a87451e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119930000/119922300/119922213/58f4802e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/120000000/119930000/119922300/119922213/941cd831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119930000/119922300/119922213/d8cb60e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Upscale Lodge Sleeps 9 Dog Friendly Near CU [](https://www.expedia.ca/Central-Hotels-Upscale-Lodge-Sleeps-9-Dog-Friendly-Near-CU.h119922213.Hotel-Information) Central CA $252 CA $510 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Central-Hotels-Upscale-Lodge-Sleeps-9-Dog-Friendly-Near-CU.h119922213.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-10&endDate=2026-03-11®ionId=553248635083907325&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=VR_SPRING_PROMO_553248635083907325) ## Find vacation rentals that suit your style Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=Pickens+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635083907325&latLong=34.883449%2C-82.707357&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=APART_HOTEL) Cabins [](https://www.expedia.ca/Hotel-Search?destination=Pickens+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635083907325&latLong=34.883449%2C-82.707357&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=CABIN) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Pickens+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635083907325&latLong=34.883449%2C-82.707357&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=APARTMENT) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Pickens+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635083907325&latLong=34.883449%2C-82.707357&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=COTTAGE) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Pickens+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635083907325&latLong=34.883449%2C-82.707357&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=VACATION_HOME) Condos [](https://www.expedia.ca/Hotel-Search?destination=Pickens+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635083907325&latLong=34.883449%2C-82.707357&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=CONDO) Villas [](https://www.expedia.ca/Hotel-Search?destination=Pickens+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635083907325&latLong=34.883449%2C-82.707357&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=VILLA) Houseboats [](https://www.expedia.ca/Hotel-Search?destination=Pickens+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635083907325&latLong=34.883449%2C-82.707357&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=HOUSE_BOAT) Chalets [](https://www.expedia.ca/Hotel-Search?destination=Pickens+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635083907325&latLong=34.883449%2C-82.707357&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Pickens-County.d553248635083907325.Vacation-Rental-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Pickens-County.d553248635083907325.Vacation-Rental-Destinations) ## Top Pickens County Hotel Reviews ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Everything was great. The room was perfect, the staff was super helpful and breakfast was outstanding. Thank you for a wonderful stay" [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. 10/10 Excellent "Everything was great! " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "The room was exceptionally clean. We particularly appreciated the services of a refreshed room daily. The staff was extremely friendly, helpful, and courteous. We plan to make this hotel our choice whenever we visit Greenville in the future. The Stewarts" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Awsome service and room" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Our king-size room was very spacious. All of the staff that we encountered were very courteous and helpful!" [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Cleanliness " [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Room was clean and spacious. Breakfast has a variety of hot and cold items." [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "Clean room, spacious and everyone was friendly. Soda has very cold drinks. They also keep the ground s well kept." [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Hotel Hartness](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6_y.jpg) ### Hotel Hartness 10/10 Excellent "Sarah provide exceptional service " [](https://expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ## Find out more about Pickens County **Everything you need to know about** **Pickens County** **vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Pickens County vacation rental for you. At Expedia, you can take your pick from [private vacation homes](https://www.expedia.ca/aa/PrivateVacationHomes), [apartments](https://www.expedia.ca/aa/Apartments), cottages, [cabins](https://www.expedia.ca/aa/Cabins), villas... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Pickens County vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Pickens County vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Pickens County. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Pickens County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. The selection of Pickens County vacation rentals we have selected for you start as low as CA $152 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Pickens County rentals** At Expedia, we put the best Pickens County vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Pickens County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Pickens County vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Pickens County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Popular Pickens County Cities - All accommodation types in Pickens County - [Clemson Vacation Rentals ](https://expedia.ca/Clemson-Vacation-Rentals.d6594.Travel-Guide-VacationRentals) - [Vacation Homes in Pickens County ](https://expedia.ca/Pickens-County-Private-Vacation-Homes.d553248635083907325-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cottages in Pickens County ](https://expedia.ca/Pickens-County-Cottages.d553248635083907325-aaCottages.Travel-Guide-Accommodation) - [Cabin Rentals in Pickens County ](https://expedia.ca/Pickens-County-Cabins.d553248635083907325-aaCabins.Travel-Guide-Accommodation) - [Apartments in Pickens County ](https://expedia.ca/Pickens-County-Apartments.d553248635083907325-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in Pickens County ](https://expedia.ca/Pickens-County-Condos.d553248635083907325-aaCondos.Travel-Guide-Accommodation) - [B&B in Pickens County ](https://expedia.ca/Pickens-County-Bed-And-Breakfast.d553248635083907325-aaBedAndBreakfast.Travel-Guide-Accommodation) - [RV Parks in Pickens County ](https://expedia.ca/Pickens-County-RV-Parks.d553248635083907325-aaRVParks.Travel-Guide-Accommodation) - [Villas in Pickens County ](https://expedia.ca/Pickens-County-Villas.d553248635083907325-aaVillas.Travel-Guide-Accommodation) - [Farmstay in Pickens County ](https://expedia.ca/Pickens-County-Agritourism.d553248635083907325-aaAgritourism.Travel-Guide-Accommodation) - [Motels in Pickens County ](https://expedia.ca/Pickens-County-Motels.d553248635083907325-aaMotels.Travel-Guide-Accommodation) - [Guest Houses in Pickens County ](https://expedia.ca/Pickens-County-Guest-Houses.d553248635083907325-aaGuestHouses.Travel-Guide-Accommodation) - [Lodges in Pickens County ](https://expedia.ca/Pickens-County-Lodges.d553248635083907325-aaLodges.Travel-Guide-Accommodation) - [Chalets in Pickens County ](https://expedia.ca/Pickens-County-Chalets.d553248635083907325-aaChalets.Travel-Guide-Accommodation) - [Resorts in Pickens County ](https://expedia.ca/Pickens-County-Resort-Hotels.d553248635083907325-aaResortHotels.Travel-Guide-Accommodation) - [Aparthotels in Pickens County ](https://expedia.ca/Pickens-County-Apart-Hotels.d553248635083907325-aaApartHotels.Travel-Guide-Accommodation) - [Inns in Pickens County ](https://expedia.ca/Pickens-County-Inns.d553248635083907325-aaInns.Travel-Guide-Accommodation) - [Houseboats in Pickens County ](https://expedia.ca/Pickens-County-Houseboats.d553248635083907325-aaHouseboats.Travel-Guide-Accommodation) - [Condo Resorts in Pickens County ](https://expedia.ca/Pickens-County-Condominium-Resort.d553248635083907325-aaCondominiumResort.Travel-Guide-Accommodation)