Title: The Best Panama Cruise Ships | Expedia.ca [Panama Travel Guide](https://expedia.ca/Panama.dx142)[Panama Hotels](https://expedia.ca/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.ca/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.ca/Destinations-In-Panama.d142.Flight-Destinations)[Things to do in Panama](https://expedia.ca/Things-To-Do-In-Panama.d142.Travel-Guide-Activities)[Panama Car Rentals](https://expedia.ca/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.ca/Panama.d142.Destination-Travel-Guides) ![Panama which includes tropical scenes, island images and landscape views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25685-Panama.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Panama Cruises ## Compare and save ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=142&startDate=2025-10-10&endDate=2025-10-12&adults=2&lodging=CRUISE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=142&startDate=2025-10-17&endDate=2025-10-19&adults=2&lodging=CRUISE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=142&startDate=2025-10-31&endDate=2025-11-02&adults=2&lodging=CRUISE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=142&startDate=2025-11-28&endDate=2025-11-30&adults=2&lodging=CRUISE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Featured Cruise Ships in Panama ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Cruise-Ships.d142-aaCruiseShips.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Cruise-Ships.d142-aaCruiseShips.Travel-Guide-Accommodation) ## Top Panama Hotel Reviews ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Verry good i drove to albrook mall " [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Waymore Hotel Spa & Casino](//images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "I encourage family and friends to take a vacation to visit Panama " [](https://expedia.ca/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Megapolis Hotel Panamá](//images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "Very good conditions and very nice breakfast. Staff kind and clean property." [](https://expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Crowne plaza is close and convenient to the airport, reliable free shuttle, easy checkin, nice restaurant. We stay here often" [](https://expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Sheraton Grand Panama](//images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "The Sheraton is a large property, so the size lends itself to several dining options, a very large gym, spacious areas to hang out. WiFi coverage was excellent." [](https://expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Waldorf Astoria Panama](//images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Staff was exceptional in every area. Made me feel at home, helped me celebrate my birthday, can't thank them enough!" [](https://expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Decapolis Hotel Panama City](//images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Good price , location and tasty breakfast " [](https://expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Novotel Panama City](//images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "Great location, friendly helpful staff, nice clean rooms, although lighting could be improved, but everything else was fine. Highly recommend it" [](https://expedia.ca/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Arcadia Condo Suites](//images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534_y.jpg) ### Arcadia Condo Suites 10/10 Excellent "Had a wonderful time here. Definitely recommend. The views from the pool were amazing. Ladies ! the lightning in the bathroom isn't the best also thought my room would have a full size mirror. Staff were friendly. " [](https://expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ## Find out more about Panama ## Panama Cruise Ships information | Number of reviews | | | --- | --- | | Accommodation | Cruise Ships | | Lowest Price | | | Highest Price | |