Search Residences in Panacea from CA $146

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Find vacation rentals that suit your style

cabin image
Cabins
Cabins
Cottage image
Cottages
Cottages

Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3
No exact matches found, but these alternatives could be just right

Recommended hotels in Panacea

A pink door with a window, set in a corrugated metal exterior with wooden trim.

1. The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (200 reviews)
"Other than everything close perfect spot"
United States
Dashawn
The price is CA $146
CA $163 total
includes taxes & fees
Dec 6 - Dec 7
The Panacea Motel
A bedroom with a bed, a TV mounted on the wall, a microwave, and a small shelf with toiletries.

2. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
9.0 out of 10, Wonderful, (2 reviews)
"Great communication. Comfortable"
United States
Faith V.
The price is CA $198
CA $239 total
includes taxes & fees
Nov 8 - Nov 9
Cozy Panacea Retreat #3 (King)
A cozy living room with a brown leather sofa, a dining table set with plates, and a view of the sea through large windows.

3. romantic get away for 2 right on the Ochlockonee river

romantic get away for 2 right on the Ochlockonee river
Panacea
6.0 out of 10, (2 reviews)
"Wonderful accommodations-clean and comfortable. "
United States
Laurie K.
The price is CA $182
CA $421 total
includes taxes & fees
Nov 8 - Nov 9
romantic get away for 2 right on the Ochlockonee river
A modern kitchen with a wooden countertop, a built-in sink, and a dining area with a table and chairs.

4. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat
Panacea
9.8 out of 10, Exceptional, (28 reviews)
"Great place to stay while fishing"
United States
Benjamin S.
The price is CA $182
CA $420 total
includes taxes & fees
Nov 9 - Nov 10
Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat
A covered outdoor area with a wooden deck, white furniture, and a view of the water.

5. Tiny Tides Waterfront Cottage

Tiny Tides Waterfront Cottage
Panacea
10.0 out of 10, Exceptional, (14 reviews)
"What a perfect escape! We thoroughly enjoyed our stay at Tiny Tides. The cozy, comfortable vibe, the peaceful location, and the easy access to everything made our trip truly special. We had a fantastic time and will definitely be back soon!"
United States
Jason W.
The price is CA $221
CA $530 total
includes taxes & fees
Nov 8 - Nov 9
Tiny Tides Waterfront Cottage
A modern building with a covered porch, a clear view of the water, and a well-maintained lawn.

6. Private beach winter escape on the bay with fishing and kayaks

Private beach winter escape on the bay with fishing and kayaks
Panacea
10.0 out of 10, Exceptional, (5 reviews)
"Wonderful view and beautiful home. Enjoyed making memories at this place"
United States
Toby H.
The price is CA $281
CA $648 total
includes taxes & fees
Nov 8 - Nov 9
Private beach winter escape on the bay with fishing and kayaks
A porch with wicker chairs and a small table, overlooking a lake and trees.

7. Point & Paddle Waterfront Retreat @Alligator Point

Point & Paddle Waterfront Retreat @Alligator Point
Alligator Point
10.0 out of 10, Exceptional, (2 reviews)
"We really enjoyed the place. It was quiet, cozy, and perfect for a quick getaway with our family. I would highly recommend others checking this place out and tho we don’t visit the area much we would love staying here again!"
United States
Scott A.
The price is CA $265
CA $650 total
includes taxes & fees
Nov 8 - Nov 9
Point & Paddle Waterfront Retreat @Alligator Point
A bedroom with a bed, a wooden door, a small table, a mirror, and a window.

8. Queen Kitchenette by the Bay #16

Queen Kitchenette by the Bay #16
Panacea
10.0 out of 10, Exceptional, (1 review)
The price is CA $198
CA $239 total
includes taxes & fees
Nov 10 - Nov 11
Queen Kitchenette by the Bay #16
A bedroom with a bed, a wooden door, a small table, a mirror, and a window.

9. 09) Queen Kitchenette by the Bay

09) Queen Kitchenette by the Bay
Panacea
The price is CA $198
CA $239 total
includes taxes & fees
Nov 8 - Nov 9
09) Queen Kitchenette by the Bay
A bedroom with a bed, a wooden door, a small table, a mirror, and a window.

10. Queen Kitchenette by the Bay #11

Queen Kitchenette by the Bay #11
Panacea
The price is CA $198
CA $239 total
includes taxes & fees
Nov 9 - Nov 10
Queen Kitchenette by the Bay #11
A small kitchen area with a wooden countertop, a coffee maker, a chair, and a table lamp.

11. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
The price is CA $198
CA $239 total
includes taxes & fees
Nov 8 - Nov 9
Cozy Panacea Retreat #3 (King)
A small kitchen area with a wooden countertop, a coffee maker, a chair, and a table lamp.

12. Cozy Panacea Retreat #7 (King)

Cozy Panacea Retreat #7 (King)
Panacea
The price is CA $198
CA $239 total
includes taxes & fees
Nov 8 - Nov 9
Cozy Panacea Retreat #7 (King)
A bedroom with a bed, a wooden door, a small table, a mirror, and a window.

13. Queen Kitchenette by the Bay #13

Queen Kitchenette by the Bay #13
Panacea
The price is CA $198
CA $239 total
includes taxes & fees
Nov 8 - Nov 9
Queen Kitchenette by the Bay #13
A bedroom with a bed, a wooden door, a small table, a mirror, and a window.

14. Queen Kitchenette by the Bay #10

Queen Kitchenette by the Bay #10
Panacea
The price is CA $198
CA $237 total
includes taxes & fees
Nov 16 - Nov 17
Queen Kitchenette by the Bay #10
A bedroom with a bed, a wooden door, a small table, a mirror, and a window.

15. Queen Kitchenette by the Bay #15

Queen Kitchenette by the Bay #15
Panacea
The price is CA $198
CA $239 total
includes taxes & fees
Nov 10 - Nov 11
Queen Kitchenette by the Bay #15
A bedroom with a bed, a wooden door, a small table, a mirror, and a window.

16. Queen Kitchenette by the Bay #14

Queen Kitchenette by the Bay #14
Panacea
The price is CA $198
CA $239 total
includes taxes & fees
Nov 10 - Nov 11
Queen Kitchenette by the Bay #14
A kitchen with a wooden countertop, a sink, and cabinets. There are shelves above the countertop holding various kitchen items.

17. Perfect Panacea 1 Bedroom Apt, #2

Perfect Panacea 1 Bedroom Apt, #2
Panacea
The price is CA $198
CA $239 total
includes taxes & fees
Nov 10 - Nov 11
Perfect Panacea 1 Bedroom Apt, #2
A modern kitchen with a central island, bar stools, stainless steel appliances, and a view of the outdoors.

18. Breezy Home w/ Grills, Pool & Beach Access!

Breezy Home w/ Grills, Pool & Beach Access!
Sopchoppy
10.0 out of 10, Exceptional, (28 reviews)
"We enjoyed the home and felt absolute comfort. We enjoyed direct beach access, bikes rides, and the pool access. We visited Alligator Point, Wakulla Springs, and St. George Island while there."
United States
Crystal
The price is CA $306
CA $771 total
includes taxes & fees
Nov 24 - Nov 25
Breezy Home w/ Grills, Pool & Beach Access!
A bedroom with a bed, a wooden door, a small table, a mirror, and a window.

19. Queen Kitchenette by the Bay #8

Queen Kitchenette by the Bay #8
Panacea
The price is CA $246
CA $293 total
includes taxes & fees
Nov 8 - Nov 9
Queen Kitchenette by the Bay #8
A wooden deck with wicker chairs and a long table, overlooking a beach and ocean.

20. The Best Beach-Front House “Get-A-Way” in Florida

The Best Beach-Front House “Get-A-Way” in Florida
Panacea
10.0 out of 10, Exceptional, (101 reviews)
"Wonderful place on the beach. My sister and I had a great time here. I especially love that the beach is dog-friendly!"
United States
Lisa R.
The price is CA $401
CA $894 total
includes taxes & fees
Nov 15 - Nov 16
The Best Beach-Front House “Get-A-Way” in Florida
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

See all hotels in Panacea
A coastal resort with beachfront villas and a clear blue sky.

Top reviews in Panacea

A fountain with a dolphin statue in a courtyard, surrounded by buildings with arched windows and a pool with blue mosaic tiles.
Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville

10/10 Excellent

Clean room, good choice in the middle of nowhere
Canada
Detlev
Reviewed January 11, 2026
Best Western Wakulla Inn & Suites

Explore a world of travel with Expedia