
Panacea Vacation Packages
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Your Panacea Vacation
When you book a vacation package to Panacea, you can relax and enjoy your getaway knowing that all your travel plans have been worked out ahead of time. Discover the wonders of this city while based in a neighborhood like Ochlockonee Bay, which is great for nature. Up for some sightseeing? A trip to Panacea isn't complete without visiting Mashes Sand Beach, Ochlockonee River State Park and other popular attractions. Check out Expedia's wide range of travel options and start organizing your ideal vacation to Panacea now.
Top Panacea Vacation Deals
Price found within the past 48 hours. Click for updated prices.

DoubleTree by Hilton Hotel Tallahassee
Capitol Hill
Price was CA $1,669, price is now CA $1,382 per person
CA $1,382
per person
Sep 6 - Sep 10
found 21 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Tallahassee (TLH)
7.4/10 Good! (1,005 reviews)
Pictures of the rooms on the website are not accurate. Did not get the room I booked and staff were unhelpful.in addressing the issue, request to be moved to a different room and was told nothing was available. Room had a very loud dehumidifier which had to run or the room smelled dank. The smallest shower enclosure I've ever been in, horrible shower head that barley worked. No microwave, no sitting chair or couch as indicated in the room description. Garage parking is very limited, no lifted trucks or high SUV can make it past the 2nd floor. Nothing to do in the immediate area.
Reviewed on Jun 21, 2026

BOB Hotels Tallahassee - Boutique on Budget
Price was CA $1,711, price is now CA $1,526 per person
CA $1,526
per person
Sep 6 - Sep 10
found 21 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Tallahassee (TLH)
9/10 Wonderful! (2,268 reviews)
Nice hotel, modern interior, good use of space in each room. Staff was very friendly. Breakfast had a tasty selection and free parking. A great value - will definitely stay again.
Reviewed on Jun 28, 2026

Staybridge Suites Tallahassee by IHG
Price was CA $1,611, price is now CA $1,450 per person
CA $1,450
per person
Sep 6 - Sep 10
found 21 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Tallahassee (TLH)
9/10 Wonderful! (1,000 reviews)
I have stayed in many hotels across the USA. This was the best. It hit every mark you would need. The lobby , clean inviting. The front desk, Holly was awesome. Friendly and did her job well. The room, clean bed comfortable and room was a suite equipped small kitchen, fridge etc. Not to ,ention the location was awesome, right off Interstate 10. Great convenience when traveling. A BIG plus was the beautiful patio out side for barbecuing, . Well maintained hotel down to the grounds around it. A DOG walk on the beautiful lake equipped with bags ..and a sidewalk to walk the dogs instead of poopy grass. All in all this deserves the hightrating because to top it off the wonderful breakfast was amazing and very clean. Good Job and cudos to a great place to stay!
Reviewed on Jun 25, 2026

La Familia Stay Inn
Price was CA $2,385, price is now CA $2,148 per person
CA $2,148
per person
Sep 6 - Sep 10
found 21 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Tallahassee (TLH)
5.6/10 (29 reviews)
Room was clean and staff was super nice. Really enjoyed my stay.
Reviewed on Dec 16, 2025

Hyatt House Tallahassee Capitol – University
Railroad Square Art District
Price was CA $1,665, price is now CA $1,527 per person
CA $1,527
per person
Sep 6 - Sep 10
found 21 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Tallahassee (TLH)
9/10 Wonderful! (1,694 reviews)
Very clean, great location.
Reviewed on Jun 27, 2026
Panacea Hotel Deals

Lighthouse- enjoy the water, bask in the view
Alligator Point FL
9.6/10 Exceptional! (9 reviews)
"Being right on the beach was excellent. The beach is very private because it is cutoff by houses."
Reviewed on Apr 14, 2026

The Panacea Motel
1545 Coastal Hwy Panacea FL
The price is CA $156 per night from Jul 13 to Jul 14
CA $156
CA $173 total
Jul 13 - Jul 14
includes taxes & fees
9/10 Wonderful! (184 reviews)
"The apartment we rented was very clean, and beautifully decorated. The staff was very helpful, friendly, and responsive to our needs."
Reviewed on Jun 27, 2026

Secluded Florida Beach Bungalow WEEKEND GETAWAY SPECIAL JULY 10-12 ONLY 199!
Panacea FL
10/10 Exceptional! (249 reviews)
"Great get away spot."
Reviewed on May 31, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.







