Panacea Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

Photo by Barbara Brogdon

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    Save up to CA $1,096 when you book a flight and hotel together*
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Your Panacea Vacation

When you book a vacation package to Panacea, you can relax and enjoy your getaway knowing that all your travel plans have been worked out ahead of time. Discover the wonders of this city while based in a neighborhood like Ochlockonee Bay, which is great for nature. Up for some sightseeing? A trip to Panacea isn't complete without visiting Mashes Sand Beach, Ochlockonee River State Park and other popular attractions. Check out Expedia's wide range of travel options and start organizing your ideal vacation to Panacea now.

Top Panacea Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Quality Inn Tallahassee near University

Quality Inn Tallahassee near University

2.5 out of 5
Price was CA $1,393, price is now CA $1,198 per person
CA $1,198
per person
Sep 20 - Sep 25
found 21 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Tallahassee (TLH)
6.8/10 (302 reviews)
The WiFi service sucks

Reviewed on Aug. 9, 2025

DoubleTree by Hilton Hotel Tallahassee

DoubleTree by Hilton Hotel Tallahassee

4 out of 5
Capitol Hill
Price was CA $2,541, price is now CA $2,004 per person
CA $2,004
per person
Sep 20 - Sep 25
found 21 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Tallahassee (TLH)
7.6/10 Good! (1,009 reviews)
Great hotel to stay at in the FSU area.

Reviewed on Aug. 18, 2025

Country Inn & Suites by Radisson, Midway - Tallahassee West

Country Inn & Suites by Radisson, Midway - Tallahassee West

2.5 out of 5
Price was CA $1,543, price is now CA $1,278 per person
CA $1,278
per person
Sep 20 - Sep 25
found 21 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Tallahassee (TLH)
7.6/10 Good! (1,003 reviews)
Great pillows, comfortable bed, clean room

Reviewed on Aug. 17, 2025

La Familia Stay Inn

La Familia Stay Inn

2 out of 5
Price was CA $2,582, price is now CA $2,194 per person
CA $2,194
per person
Sep 20 - Sep 25
found 21 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Tallahassee (TLH)
5.2/10 (19 reviews)
It was clean. Room needs upgrade

Reviewed on May 4, 2025

Hampton Inn & Suites Tallahassee Capitol - University

Hampton Inn & Suites Tallahassee Capitol - University

2.5 out of 5
Railroad Square Art District
Price was CA $2,283, price is now CA $1,954 per person
CA $1,954
per person
Sep 20 - Sep 25
found 21 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Tallahassee (TLH)
9.2/10 Wonderful! (1,001 reviews)
The breakfast was really bad

Reviewed on Aug. 15, 2025

Ready to book your vacation to Panacea?

 

Choose your dates

Panacea Hotel Deals

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

Alligator Point
The price is CA $971 per night from Aug 23 to Aug 24
CA $971
CA $2,654 total
Aug 23 - Aug 24
includes taxes & fees
9.8/10 Exceptional! (98 reviews)
"We had an awesome time. Wonderful well stocked home. We will definitely be back."

Reviewed on Jul. 27, 2025

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
The Panacea Motel

The Panacea Motel

2 out of 5
1545 Coastal Hwy, Panacea, FL
The price is CA $149 per night from Aug 24 to Aug 25
CA $149
CA $166 total
Aug 24 - Aug 25
includes taxes & fees
9/10 Wonderful! (108 reviews)
"Historical little place but clean and comfortable. Met the manager and she was a busy little gal and willing to help! A/C works great!"

Reviewed on Aug. 16, 2025

The Panacea Motel
Secluded Florida Beach Bungalow SPECIAL!!! 10% OFF ANYTIME JUNE 6-JUNE 13TH

Secluded Florida Beach Bungalow SPECIAL!!! 10% OFF ANYTIME JUNE 6-JUNE 13TH

Panacea, FL
9.8/10 Exceptional! (221 reviews)
"The retro/beach themes of the house were cool. The house was very clean and had everything we needed. Loved the screened in porch. Tides affected beach access at the end of the street, but there are other public beach access available."

Reviewed on Aug. 12, 2025

Get rates
Secluded Florida Beach Bungalow SPECIAL!!! 10% OFF ANYTIME JUNE 6-JUNE 13TH
See all 496 properties in Panacea
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Panacea

USS Mohawk CGC Veterans Memorial Reef

You can find out about the history of Panacea with a visit to USS Mohawk CGC Veterans Memorial Reef. Wander around the natural setting in this relaxing area, or simply enjoy its seafood restaurants.

USS Mohawk CGC Veterans Memorial Reef

Frequently asked questions

How much does a Panacea vacation package cost?
You can grab a vacation package to this popular destination from CA $1,198 on Expedia. But how much your vacation to Panacea costs will depend on the length of stay, season and hotel choice.
What are the cheapest months to go to Panacea?
December, January and February are the best times to search for cheap Panacea vacation packages. Travelling in less busy months means you can typically find reduced prices on hotels and flights.
How many days is enough for Panacea?
The ideal duration of your Panacea vacation depends on what you'd like to do and see. Usually, a handful of days to a week will give you enough time to hit all the main sights and discover some hidden spots along the way.
How to find the best Panacea package deals?
Bagging a cheap Panacea package deal is a cinch with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can fine-tune your search by "Area," "Amenities," "Property type" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Panacea package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book a Panacea vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, hotel and car rental into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component individually. And you'll still enjoy the flexibility to create a tailored Panacea vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Panacea?
If you have your Panacea travel dates finalized, book as soon as you can to grab some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for jetting off on a whim.
How to plan a trip to Panacea?

  1. Choose your dates: What you plan to do in Panacea and your preferred season will help you decide when to travel.
  2. Work out your budget: Ensure you have enough money to pay for everything from transportation and dining out to airfares and activities. Your hotel will probably be the biggest expense during your trip to Panacea.
  3. Set the duration of your trip: Start by listing all the activities and attractions you want to experience in Panacea. Then, estimate how long you'll need at each, including any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a tailored Panacea vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.