Title: Panacea Vacation Rentals from CA $2,686: Short-Term Rentals for 2026 | Expedia.ca

[Panacea Travel Guide](https://expedia.ca/Panacea.dx3000431554)[Hotels in Panacea](https://expedia.ca/Panacea-Hotels.d3000431554.Travel-Guide-Hotels)[Panacea Car Rentals](https://expedia.ca/Car-Rentals-In-Panacea.d3000431554.Car-Rental-Guide)[Panacea Vacation Packages](https://expedia.ca/Panacea.d3000431554.Destination-Travel-Guides)

![Sunset over a lake at Panacea, northern Florida, USA | NONE |](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Panacea vacation rentals

![Beach](https://images.trvl-media.com/lodging/113000000/112950000/112942400/112942331/e5db1abd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112950000/112942400/112942331/bc45e68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/113000000/112950000/112942400/112942331/b2afa767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/113000000/112950000/112942400/112942331/a4523a31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Panacea Retreat #3 (King)

[](https://www.expedia.ca/Panacea-Hotels-Cozy-Panacea-Retreat-3.h112942331.Hotel-Information)

Panacea

8.0/10

Very good

(1 review)

"The room is a typical motel room as expected. Loved the retro fridge and microwave!Hosts were extremely accommodating and friendly. Thank you"

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Janine C.

CA $169

CA $215 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Cozy-Panacea-Retreat-3.h112942331.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/123000000/122120000/122111100/122111093/b0e689e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122120000/122111100/122111093/2d8aa8b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/123000000/122120000/122111100/122111093/6c75a857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/123000000/122120000/122111100/122111093/1f3d2a77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### romantic get away for 2 right on the Ochlockonee river

[](https://www.expedia.ca/Panacea-Hotels-Romantic-Get-Away-For-2-Right-On-The-Ochlockonee-River.h122111093.Hotel-Information)

Panacea

10/10

Exceptional

(1 review)

"Wonderful accommodations-clean and comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laurie K.

CA $178

CA $429 total

includes taxes & fees

Feb 10 - Feb 11

[](https://www.expedia.ca/Panacea-Hotels-Romantic-Get-Away-For-2-Right-On-The-Ochlockonee-River.h122111093.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/117000000/116790000/116784100/116784001/a1fd53d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/117000000/116790000/116784100/116784001/b2492e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116784100/116784001/6a1354bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/117000000/116790000/116784100/116784001/20ef87c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private Beach & Dock - Quiet Waterfront Retreat on Ochlockonee Bay

[](https://www.expedia.ca/Panacea-Hotels-Private-Beach-Dock-Quiet-Waterfront-Retreat-On-Ochlockonee-Bay.h116784001.Hotel-Information)

Panacea

CA $202

CA $570 total

includes taxes & fees

Feb 18 - Feb 19

[](https://www.expedia.ca/Panacea-Hotels-Private-Beach-Dock-Quiet-Waterfront-Retreat-On-Ochlockonee-Bay.h116784001.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/121000000/120280000/120270500/120270445/29b9886d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/121000000/120280000/120270500/120270445/9a035d54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120280000/120270500/120270445/9e91ad83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sun loungers, beach towels](https://images.trvl-media.com/lodging/121000000/120280000/120270500/120270445/713cab07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Point & Paddle Waterfront Retreat @Alligator Point

[](https://www.expedia.ca/Panacea-Hotels-Alligator-Point-Paddle-Pond-Home-Short-Walk-To-The-Beach.h120270445.Hotel-Information)

Alligator Point

10/10

Exceptional

(1 review)

"Not only is this house adorable and roomy, it is the perfect mix of secluded and convenient. I hosted my girls for a little weekend birthday celebration and we had the best time watching the sunset from the dock, then enjoying a bonfire with smores! We played games and laughed well in to the night before finally retiring to the super comfy beds. The next morning we took the short walk to the beach and enjoyed discovering all types of nature while walking through the beaches of bald point state...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Holley C.

CA $383

CA $820 total

includes taxes & fees

Mar 4 - Mar 5

[](https://www.expedia.ca/Panacea-Hotels-Alligator-Point-Paddle-Pond-Home-Short-Walk-To-The-Beach.h120270445.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547023/debbcb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547023/2d400668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547023/17d21d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547023/c0425b17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Panacea Retreat #3 (King)

[](https://www.expedia.ca/Panacea-Hotels-Cozy-Panacea-Retreat-3.h121547023.Hotel-Information)

Panacea

CA $169

CA $215 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Cozy-Panacea-Retreat-3.h121547023.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547053/4acea5b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547053/8504ddb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547053/81dd3aeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547053/70ef9d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Panacea Retreat #7 (King)

[](https://www.expedia.ca/Panacea-Hotels-Cozy-Panacea-Retreat-7.h121547053.Hotel-Information)

Panacea

CA $169

CA $215 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Cozy-Panacea-Retreat-7.h121547053.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/122000000/121880000/121872500/121872496/676a078e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/122000000/121880000/121872500/121872496/25ea066f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/122000000/121880000/121872500/121872496/99d04bec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![On the beach](https://images.trvl-media.com/lodging/122000000/121880000/121872500/121872496/a6cfc0b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### This Cape Cod style beauty will make you fall in love with the Forgotten Coast!

[](https://www.expedia.ca/Panacea-Hotels-This-Cape-Cod-Style-Beauty-Will-Make-You-Fall-In-Love-With-The-Forgotten-Coast.h121872496.Hotel-Information)

Alligator Point

10/10

Exceptional

(5 reviews)

"By the way, this place has been amazing watching the dolphin play in the shallows every day and the beautiful sunrises, easy access down the street to the beach for fishing and walking. This is exactly what the doctor ordered. The home is beautifully and the views are extraordinary. Comfy bed in master looking out over the gulf. We spent most of our time on the huge deck. You have a really great place here."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David L.

CA $433

CA $861 total

includes taxes & fees

Feb 20 - Feb 21

[](https://www.expedia.ca/Panacea-Hotels-This-Cape-Cod-Style-Beauty-Will-Make-You-Fall-In-Love-With-The-Forgotten-Coast.h121872496.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547082/0af239f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547082/98483b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547082/48a381b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547082/13e11b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 09) Queen Kitchenette by the Bay

[](https://www.expedia.ca/Panacea-Hotels-09-Queen-Kitchenette-By-The-Bay.h121547082.Hotel-Information)

Panacea

CA $192

CA $241 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-09-Queen-Kitchenette-By-The-Bay.h121547082.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547164/366856fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547164/6edfdcd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547164/eb981fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547164/383e28c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Kitchenette by the Bay #15

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-15.h121547164.Hotel-Information)

Panacea

CA $192

CA $241 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-15.h121547164.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547124/8277bb47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547124/a6a220d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547124/7ccf5fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547124/fc8b590d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Kitchenette by the Bay #12

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-12.h121547124.Hotel-Information)

Panacea

CA $192

CA $241 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-12.h121547124.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547148/c13195b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547148/9609ba16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547148/124ab8cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547148/5142474a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Kitchenette by the Bay #14

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-14.h121547148.Hotel-Information)

Panacea

CA $192

CA $241 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-14.h121547148.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547174/e6dd40c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547174/84444893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547174/7083d6e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547174/deeee0a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Kitchenette by the Bay #16

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-16.h121547174.Hotel-Information)

Panacea

CA $192

CA $241 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-16.h121547174.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547095/f1e8b85e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547095/27152a55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547095/825655e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547100/121547095/4b3c6320.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Kitchenette by the Bay #10

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-10.h121547095.Hotel-Information)

Panacea

CA $192

CA $241 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-10.h121547095.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547110/dacdf48b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547110/ed3a4685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547110/8e791adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547110/96116d33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Kitchenette by the Bay #11

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-11.h121547110.Hotel-Information)

Panacea

CA $192

CA $241 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-11.h121547110.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547139/9d969f5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547139/9f07c512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547139/3bc0390e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547139/78c013f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Kitchenette by the Bay #13

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-13.h121547139.Hotel-Information)

Panacea

CA $192

CA $241 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-13.h121547139.Hotel-Information)

![On the beach](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/da44be87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/cb91d7d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace, DVD player, foosball](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/6ddf58b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/8fcbe9b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

[](https://www.expedia.ca/Panacea-Hotels-7-Bedroom-Beach-House-With-POOL-Gulf-Front-And-Bay-Front.h19008298.Hotel-Information)

Alligator Point

10/10

Exceptional

(122 reviews)

"Love this house! Plenty of beds, great views and the house was stocked as well as I’ve ever seen in a rental property (I’m serious!!!). Thank you!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Scott G.

CA $957

CA $2,686 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-7-Bedroom-Beach-House-With-POOL-Gulf-Front-And-Bay-Front.h19008298.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/116000000/115460000/115458600/115458502/ccee74a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/116000000/115460000/115458600/115458502/e0212a42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/116000000/115460000/115458600/115458502/07b6fb25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115460000/115458600/115458502/09177221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### NEW - St. Teresa Beach Escape w/ Private Beach Acc

[](https://www.expedia.ca/Panacea-Hotels-NEW-St-Teresa-Beach-Escape-W-Private-Beach-Acc.h115458502.Hotel-Information)

Lanark Village

CA $274

CA $765 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-NEW-St-Teresa-Beach-Escape-W-Private-Beach-Acc.h115458502.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547191/99ff6b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547191/37429d6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547191/46192bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/122000000/121550000/121547200/121547191/f0a1f85d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Kitchenette by the Bay #17

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-17.h121547191.Hotel-Information)

Panacea

CA $224

CA $279 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Queen-Kitchenette-By-The-Bay-17.h121547191.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/92000000/91690000/91683300/91683282/7c4c9d37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/92000000/91690000/91683300/91683282/e77af822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91690000/91683300/91683282/ae947836.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace, books](https://images.trvl-media.com/lodging/92000000/91690000/91683300/91683282/948acf56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spring Break & Beyond — Waterfront Living, Wraparound Deck & Boating Access!

[](https://www.expedia.ca/Panacea-Hotels-Waterfront-Luxury-Home-With-Dock.h91683282.Hotel-Information)

Alligator Point

10/10

Exceptional

(4 reviews)

"Great house and location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erin P.

[](https://www.expedia.ca/Panacea-Hotels-Waterfront-Luxury-Home-With-Dock.h91683282.Hotel-Information)

![1 bedroom, desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112980000/112971700/112971601/4dd911d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112980000/112971700/112971601/0dd7d7b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels](https://images.trvl-media.com/lodging/113000000/112980000/112971700/112971601/9bfe8e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/113000000/112980000/112971700/112971601/0759e8a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Panacea Cozy Retreat #4 (DQ)

[](https://www.expedia.ca/Panacea-Hotels-Panacea-Cozy-Retreat-4.h112971601.Hotel-Information)

Panacea

CA $240

CA $298 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panacea-Hotels-Panacea-Cozy-Retreat-4.h112971601.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-22&endDate=2026-02-23&regionId=3000431554&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cottages

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Cabins

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Private vacation homes

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Condos

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Apartments

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Houseboats

[](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America&regionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-05-08&d1=2026-05-08&endDate=2026-05-11&d2=2026-05-11&lodging=HOUSE_BOAT)

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## Top Panacea Hotel Reviews

![Hideaway Beach Cottage on waterfront with amazing views.](https://images.trvl-media.com/lodging/89000000/89000000/88994400/88994349/3f6eb453_y.jpg)

### Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent

"Host is amazing! Thank you Agnus for sharing your hospitality and house. The property is beautiful and exactly as expected. Sunrises and sunsets on the river doesn’t get any better than this location. Lots of space and a really comfortable bed. The rv park next door was extremely quiet and not an issue. Near by restaurants were amazing— Angelo’s, Trident , tropical trader are must do!!I see why this host and property get 5 star reviews over and over again. I can’t think of anything that would make this vacation any better. "

[](https://expedia.ca/Panacea-Hotels-Hideaway-Beach-Cottage-On-Waterfront-With-Amazing-Views.h88994349.Hotel-Information)

![Best deal at Alligator Point](https://images.trvl-media.com/lodging/34000000/33490000/33486800/33486730/f2e6bb56_y.jpg)

### Best deal at Alligator Point

10/10 Excellent

"All excellent."

[](https://expedia.ca/Panacea-Hotels-Best-Deal-At-Alligator-Point.h33486730.Hotel-Information)

![PRIVATE LUXURY BEACHFRONT HOME!](https://images.trvl-media.com/lodging/56000000/55370000/55361200/55361115/c761bdff_y.jpg)

### PRIVATE LUXURY BEACHFRONT HOME!

10/10 Excellent

"We absolutely loved this house. It is extremely well appointed throughout. Location unbeatable. Owner was very helpful and very easy to contact. We will definitely rent this house again."

[](https://expedia.ca/Panacea-Hotels-NEW-5-Bedroom-5-Bathroom-Beachfront-Home-With-Views-From-Every-Room.h55361115.Hotel-Information)

![Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +](https://images.trvl-media.com/lodging/108000000/107290000/107284100/107284077/5342dafe_y.jpg)

### Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

10/10 Excellent

"What a wonderful way to spend a few days. Great listing, well equipped with everything you could possibly need for fun time at the beach. Each day begins with a sunrise right over the water. Even in the winter, this home is well equipped for a great time. I especially enjoyed the stars and spending the evening by the fire, in the hot tub and sauna. Would stay again. Thank you so much for the hospitality, Osbourne."

[](https://expedia.ca/Panacea-Hotels-Private-Beachfront-W-Golf-Cart.h107284077.Hotel-Information)

![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg)

### The Panacea Motel

10/10 Excellent

"The room was clean. the ac was great"

[](https://expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information)

![Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach](https://images.trvl-media.com/lodging/99000000/98480000/98476700/98476634/9da6b804_y.jpg)

### Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach

10/10 Excellent

"Melynda is an amazing host. Melynda's home is what all other vacation rentals should aspire to become. The house is spotless and well stocked. The amenities are amazing. The beds are comfortable and you will miss the shower when you get home. The location is fantastic. The neighbor is very kind. The beach is quiet. We walked for miles every day and collected huge shells. Our dogs loved the walks and the dolphins put on quite a show. The sunrises and sunsets are phenomenal and I hope everyone can experience a foggy day while at Alligator point...pure magic. We cooked from scratch meals every day and had literally everything we needed. We look forward to returning to this home. Melynda goes above and beyond to care for her guests and her home. "

[](https://expedia.ca/Panacea-Hotels-Oceanfront-Private-Beach-Beautifully-Decorated-Remodeled-On-121-Acres.h98476634.Hotel-Information)

![ Charming Alligator Point "Old Florida” Beach Cottage ](https://images.trvl-media.com/lodging/35000000/34590000/34581200/34581134/2c943c28_y.jpg)

###  Charming Alligator Point "Old Florida” Beach Cottage 

10/10 Excellent

"The cottage is perfectly clean and furnished with many cozy touches as well as beautiful art. Wendy is one of the most friendly and welcoming hosts of any place where we've visited. What we enjoy the most about the house is the location in a quiet, non-crowded area away from traffic, with only the birds and sea life surrounding us. The view of sunrise and sunset from the screened porch is beyond compare!"

[](https://expedia.ca/Panacea-Hotels-Charming-Alligator-Point-Old-Florida-Beach-Cottage.h34581134.Hotel-Information)

![Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay](https://images.trvl-media.com/lodging/107000000/106380000/106377800/106377762/82e3e83b_y.jpg)

### Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay

10/10 Excellent

"Vert nice house, very clean and confortable , perfect for relax and fish on the dock, amazing fish, really nice host....ty nancy "

[](https://expedia.ca/Panacea-Hotels-Waterfront-Home-200-Ft-Pier1st-Floor.h106377762.Hotel-Information)

![The Best Beach-Front House “Get-A-Way” in Florida](https://images.trvl-media.com/lodging/69000000/68410000/68408000/68407918/0a19b2c0_y.jpg)

### The Best Beach-Front House “Get-A-Way” in Florida

10/10 Excellent

"Everything we needed!"

[](https://expedia.ca/Panacea-Hotels-The-Best-Beach-Front-House-Get-A-Way-In-Florida.h68407918.Hotel-Information)

## Find out more about Panacea

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Panacea. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

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- [Vacation Homes in Panacea ](https://expedia.ca/Panacea-Private-Vacation-Homes.d3000431554-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cottages in Panacea ](https://expedia.ca/Panacea-Cottages.d3000431554-aaCottages.Travel-Guide-Accommodation)
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- [B&B in Panacea ](https://expedia.ca/Panacea-Bed-And-Breakfast.d3000431554-aaBedAndBreakfast.Travel-Guide-Accommodation)

## Frequently asked questions

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