Title: Book The Best Hotels in Panacea, FL for 2026 from CA $122 - Fully Refundable Options - Expedia.ca [Panacea Travel Guide](https://expedia.ca/Panacea.dx3000431554)[Vacation Rentals in Panacea](https://expedia.ca/Panacea-Vacation-Rentals.d3000431554.Travel-Guide-VacationRentals)[Panacea Car Rentals](https://expedia.ca/Car-Rentals-In-Panacea.d3000431554.Car-Rental-Guide)[Panacea Vacation Packages](https://expedia.ca/Panacea.d3000431554.Destination-Travel-Guides) ![Sunset over a lake at Panacea, northern Florida, USA | NONE |](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd/coastal-bay-sunset-seagulls-golden-hour-reflection-marsh-grass.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Panacea, FL from CA $122 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Panacea Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&amenities=PETS) Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&amenities=OCEAN_VIEW) Pool [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&amenities=POOL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&travelerType=family_friendly) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&lodging=COTTAGE) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&lodging=APARTMENT) Condo [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&lodging=CONDO) ## Check prices for these dates Tonight [Dec 6 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2025-12-06&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 7 - Dec 8](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2025-12-07&endDate=2025-12-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 499 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Exterior](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cottage | Terrace/patio](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/1434ed07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/41d5ba19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio | Living area](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f2711545.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Panacea Motel Panacea 9.0/10 Wonderful (135) "A v nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Harry [](https://www.expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/99ac7a1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/83d33573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/1d7bfd3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/0434072d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Wakulla Springs Crawfordville 9.4/10 Exceptional (1001) "Great stay. Boat tour was enjoyable. Quiet relaxing place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) PATRICIA [](https://www.expedia.ca/Tallahassee-Hotels-The-Lodge-At-Wakulla-Springs.h5411745.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/f9b0d233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/8b183b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/4f65d9b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/4ed5cee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wildwood Inn Crawfordville 8.6/10 Excellent (1002) "Enjoyed our stay and would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey CA $159 CA $182 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Crawfordville-Hotels-Wildwood-Inn.h1532906.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/bb4da5df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/aa3b7e23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/a49c599c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/fc5eefa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St James Bay Golf & Pickleball Resort Carrabelle 9.0/10 Wonderful (366) "The facility and amenities were wonderful! Everyone was so friendly and helpful. Our pup enjoyed his stay also. We will be back for sure! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy CA $195 CA $215 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Carrabelle-Hotels-St-James-Bay-Golf-Club.h23962755.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/9ff25f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/a52a90f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/d2b9dc16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/25adabe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Wakulla Inn & Suites Crawfordville 8.8/10 Excellent (945) "Great hotel. Very good customer service and very clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) claudina CA $154 CA $171 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/f34571a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/413778f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/b073fdcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Condo, 2 Double Beds, River View | Private kitchen](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/e1c75ab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Moorings Hotel and Marina Carrabelle 8.4/10 Very good (39) "Hotel was really nice and convenient to everything we wanted to do in the area. Very quiet and peaceful. Bed was a little uncomfortable, but that's a personal preference thing and I won't fault them for that. Really nice staff and easy check in and check out. Would definitely return!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl CA $185 CA $205 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Carrabelle-Hotels-The-Moorings-Hotel-And-Marina.h103241082.Hotel-Information) ![Suite, Courtyard View | Bathroom](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/870a062f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/551331a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/6ead64bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/d32c866d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Old Carrabelle Hotel Carrabelle CA $188 CA $208 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Carrabelle-Hotels-The-Old-Carrabelle-Hotel.h121767092.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/4470f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/9928e089.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/0c5660d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/c81957b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Franklin Inn Carrabelle 7.8/10 Good (453) "JJ was great great location clean room comfortable bed and good value. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal CA $110 CA $122 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Carrabelle-Hotels-Franklin-Inn.h45034076.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-20&endDate=2025-12-21®ionId=3000431554&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Panacea, FL Showing deals for:**Dec 19 - Dec 21** ### Image gallery for The Panacea Motel ![Exterior](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Panacea Motel Panacea **9.0/10**Wonderful (135 reviews) 10% off CA $160 CA $356 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=95071987&adults=2) ### Image gallery for Hideaway Beach Cottage on waterfront with amazing views. ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/89000000/89000000/88994400/88994349/3f6eb453.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hideaway Beach Cottage on waterfront with amazing views. Panacea **10/10**Exceptional (57 reviews) 10% off CA $247 CA $871 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=88994349&adults=2) ### Image gallery for Coastal Getaway on canal-steps to the beach ![Terrace/patio](https://images.trvl-media.com/lodging/79000000/78440000/78437300/78437246/22f909a1.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Coastal Getaway on canal-steps to the beach Panacea **9.8/10**Exceptional (58 reviews) 10% off CA $178 CA $442 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=78437246&adults=2) ### Image gallery for 5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/75000000/74830000/74824400/74824331/169d337b.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### 5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch Panacea **10/10**Exceptional (79 reviews) 5% off CA $316 CA $1,176 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=74824331&adults=2) ### Image gallery for CONDO Water front, bay breeze, fishing paradise and family friendly 2 bedroom ![Outdoor pool](https://images.trvl-media.com/lodging/36000000/35160000/35159200/35159189/85f95ba1.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### CONDO Water front, bay breeze, fishing paradise and family friendly 2 bedroom Panacea **9.4/10**Exceptional (111 reviews) 10% off CA $160 CA $651 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=35159189&adults=2) ### Image gallery for Point & Paddle Waterfront Retreat @Alligator Point ![Sun loungers, beach towels](https://images.trvl-media.com/lodging/121000000/120280000/120270500/120270445/23c0dcf6.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Point & Paddle Waterfront Retreat @Alligator Point Panacea **10/10**Exceptional (1 review) 20% off CA $221 CA $896 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=120270445&adults=2) ### Image gallery for Sunsets & Serenity: Tranquil Waterfront Escape on the Ochlockonee in Panacea ![Terrace/patio](https://images.trvl-media.com/lodging/72000000/72000000/71999100/71999023/87ae0e0d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Sunsets & Serenity: Tranquil Waterfront Escape on the Ochlockonee in Panacea Panacea **9.6/10**Exceptional (20 reviews) 10% off CA $280 CA $1,125 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=71999023&adults=2) ### Image gallery for Gulf Coast Getaway Steps To Beach Dog Friendly Fenced Yard Ground Level Bedrooms ![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/77000000/76790000/76789600/76789558/b93bcea1.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Gulf Coast Getaway Steps To Beach Dog Friendly Fenced Yard Ground Level Bedrooms Panacea **10/10**Exceptional (38 reviews) 10% off CA $298 CA $1,131 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=76789558&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Hotels.d3000431554.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Hotels.d3000431554.Travel-Guide-Hotels) ## Learn more about Panacea Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails. [See all hotels in Panacea](https://www.expedia.ca/Hotel-Search?startDate=2025-12-20&endDate=2025-12-21&adults=2®ionId=3000431554) ![Sunset over a lake at Panacea, northern Florida, USA | NONE |](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd.jpg?impolicy=fcrop&w=267&h=399&p=1&q=high) ### Stay near popular Panacea attractions [](https://expedia.ca/Bald-Point-State-Park-Hotels.0-l553248621532654045-0.Travel-Guide-Filter-Hotels) ![Bald Point State Park](https://mediaim.expedia.com/destination/1/a26f5e12f28d6a9b90f0a1284fcb27fc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Bald Point State Park You can take time to visit Bald Point State Park during your travels to Alligator Point. Stroll along the beaches in this relaxing area, or seek out the fishing spots. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654045) [](https://expedia.ca/Alligator-Point-Beach-Hotels.0-l553248635983992302-0.Travel-Guide-Filter-Hotels) #### Alligator Point Beach Why not spend a lazy afternoon at Alligator Point Beach during your trip to Alligator Point? [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635983992302) [](https://expedia.ca/Mashes-Sand-Beach-Hotels.0-l553248635983994375-0.Travel-Guide-Filter-Hotels) #### Mashes Sand Beach Why not spend a lazy afternoon at Mashes Sand Beach during your trip to Panacea? Amble around this relaxing area's beaches, or seek out the fishing spots. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635983994375) [](https://expedia.ca/USS-Mohawk-CGC-Veterans-Memorial-Reef-Hotels.0-l553248621561885546-0.Travel-Guide-Filter-Hotels) #### USS Mohawk CGC Veterans Memorial Reef You can find out about the history of Panacea with a visit to USS Mohawk CGC Veterans Memorial Reef. Wander around the natural setting in this relaxing area, or simply enjoy its seafood restaurants. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561885546) ## More cheap stays in Panacea ![Best Western Wakulla Inn & Suites](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/9ff25f41_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Wakulla Inn & Suites 3292 Coastal Hwy 98 Crawfordville FL CA $154 CA $171 total Jan 1 - Jan 2, 2026 includes taxes & fees 8.6/10 Excellent! (944 reviews) [](https://expedia.ca/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information) ![Franklin Inn](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/4470f88b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Franklin Inn 1589 US-98 Carrabelle FL CA $110 CA $122 total Dec 10 - Dec 11 includes taxes & fees 7.8/10 Good! (453 reviews) [](https://expedia.ca/Carrabelle-Hotels-Franklin-Inn.h45034076.Hotel-Information) ![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Panacea Motel 1545 Coastal Hwy Panacea FL [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F12%2F2025&endDate=21%2F12%2F2025&selected=95071987&PinnedHotelID=95071987&HadPinnedHotel=true®ionId=3000431554) 9/10 Wonderful! (135 reviews) [](https://expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![The Moorings Hotel and Marina ](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/f34571a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Moorings Hotel and Marina 1000 Hwy 98 Carrabelle FL CA $185 CA $205 total Dec 10 - Dec 11 includes taxes & fees 8.4/10 Very Good! (39 reviews) [](https://expedia.ca/Carrabelle-Hotels-The-Moorings-Hotel-And-Marina.h103241082.Hotel-Information) ![Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!](https://images.trvl-media.com/lodging/122000000/121250000/121245500/121245426/1c35e8cb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets! Crawfordville FL CA $214 CA $487 total Dec 9 - Dec 10 includes taxes & fees 10/10 Exceptional! (2 reviews) [](https://expedia.ca/Crawfordville-Hotels-Shell-Point-Canal-Front-Home-Come-Enjoy-A-Carefree-Comfortable-Stay-In-Paradise.h121245426.Hotel-Information) ![Pet friendly Kayak with the manatees](https://images.trvl-media.com/lodging/109000000/108410000/108408700/108408667/dad3a8f0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pet friendly Kayak with the manatees Crawfordville FL [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F12%2F2025&endDate=21%2F12%2F2025&selected=108408667&PinnedHotelID=108408667&HadPinnedHotel=true®ionId=3000431554) 9.8/10 Exceptional! (44 reviews) [](https://expedia.ca/Crawfordville-Hotels-Charming-3-Bedroom-House-With-AC-And-WiFi-In-Crawfordville.h108408667.Hotel-Information) ## Hotels in Panacea with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 45 properties [](https://expedia.ca/3Star-Panacea-Hotels.s30-0-d3000431554.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 35 properties [](https://expedia.ca/2Star-Panacea-Hotels.s20-0-d3000431554.Travel-Guide-Filter-Hotels) ## Find out more about Panacea ### Top reasons to visit Panacea - **Scenic Beaches:** Panacea boasts beautiful, inviting beaches perfect for relaxation and fun in the sun. - **Outdoor Adventures:** Enjoy recreational activities in nearby national and state parks, ideal for nature lovers. - **Charming Neighborhoods:** Explore family-friendly areas with friendly locals that enhance the coastal experience. - **Diverse Accommodations:** Find a range of pet-friendly lodging options, from cozy guesthouses to comfortable motels. - **Ideal Base for Exploration:** Panacea's central location makes it a great starting point for discovering nearby attractions. ### Find great hotels near Panacea Discover the charm of Panacea, Florida, where a variety of lodging options await you. Whether you’re looking for a cozy guesthouse or a comfortable motel, you’ll find pet-friendly accommodations that cater to your adventure and business needs. Explore top hotels and vacation homes that provide a welcoming atmosphere, ensuring a memorable stay in this picturesque coastal town. - **[Hyatt House Tallahassee Capitol – University: ](https://www.expedia.ca/Tallahassee-Hotels-Hyatt-House-Tallahassee-Capitol-Univer.h58811398.Hotel-Information)** This 3-star hotel offers a welcoming atmosphere tailored for both family and business travellers. Located 46.7km from Panacea, it features a range of amenities that include a Business Centre and accessible meeting rooms, making it perfect for professionals on the go. Families will appreciate the thoughtful touches such as cribs for infants and safety window guards for children. Additionally, the hotel is pet-friendly, allowing you to bring your furry companions along for the adventure. With its blend of comfort and practicality, it's an excellent choice for a well-rounded vacation experience. - **[Best Western Wakulla Inn & Suites: ](https://www.expedia.ca/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information)** Situated only 9.7km from Panacea, this hotel is ideal for those seeking adventure alongside business amenities. With a 24-hour Business Centre and multiple meeting rooms, it caters to corporate needs while also providing a playground for outdoor enthusiasts. Guests can embark on nearby adventures like hiking, snorkeling, or sailing. Whether you're winding down after a day of meetings or seeking thrills in nature, the Best Western Wakulla Inn & Suites offers a perfect blend of professional and recreational opportunities. - **[Magnuson Hotel Wildwood Inn: ](https://www.expedia.ca/Crawfordville-Hotels-Wildwood-Inn.h1532906.Hotel-Information)** Located 11.3km from Panacea, this 3-star hotel combines adventure, business facilities, and a pet-friendly environment. Its business amenities include accessible meeting rooms and a Business Centre, making it a suitable option for travelling professionals. Guests can indulge in various outdoor activities such as mountain biking, fishing, and sailing nearby. The hotel also welcomes pets, which makes it a great choice for those who want to bring their four-legged friends along. It's a versatile option for visitors looking for both work and play. ### Where to stay in Panacea Panacea, Florida, offers a delightful blend of serene beaches and outdoor adventures, making it an ideal spot for a relaxing getaway. Just a short stroll from the coast, you'll find charming neighborhoods with a family-friendly atmosphere and friendly locals. Explore the stunning shoreline, indulge in romantic escapes, and soak up the coastal vibe that defines this picturesque region. With its central location, Panacea serves as a perfect base for discovering nearby attractions and creating unforgettable memories. - **[Alligator Point: ](https://www.expedia.ca/Alligator-Point-Hotels.d553248635975849030.Travel-Guide-Hotels)** Nestled along the Gulf Coast, Alligator Point is a charming village near Panacea known for its tranquil beaches and outdoor experiences. The village offers a serene atmosphere, especially from May to July when visitor numbers peak. Here, you can indulge in activities such as golfing, or relax at the local resorts. The nearby beach and national state park provide stunning scenery, while the wetlands serve as a habitat for diverse wildlife, making it perfect for nature enthusiasts and photographers alike. - **[Saint Teresa: ](https://www.expedia.ca/Saint-Teresa-Hotels.d3000432006.Travel-Guide-Hotels)** Located just a stone's throw away from Panacea, Saint Teresa is a delightful village that attracts visitors seeking a peaceful retreat. With peak travel times in March and June to July, this area is well-loved for its beautiful beaches and outdoor recreational opportunities. Golfing enthusiasts will find several courses nearby, while the surrounding national state park and wetlands offer ample chances for exploration and relaxation. Saint Teresa is an ideal spot to enjoy the natural beauty of Florida’s coast. - **[Ochlockonee Bay: ](https://www.expedia.ca/Ochlockonee-Bay-Hotels.d553248635975855809.Travel-Guide-Hotels)** Ochlockonee Bay, another picturesque village near Panacea, is a haven for those who crave adventure and scenic views. Travellers flock here from May to July, drawn by its outdoor activities and stunning landscapes. The village features a range of recreational areas and resorts, perfect for unwinding after a day of exploration. With its proximity to beautiful beaches and the national state park, Ochlockonee Bay offers a unique blend of relaxation and adventure, making it a must-visit on your Florida getaway. ### Things to do in and around Panacea Panacea, Florida, offers a delightful getaway for those seeking beach and outdoor adventures amidst beautiful scenery. Visitors can explore various attractions, including recreational areas and educational spots, while enjoying the comforts of local resorts. Whether you're looking to relax by the beach or engage in outdoor activities, Panacea provides a perfect blend of leisure and exploration, making it an ideal destination for a memorable vacation. **Shopping** In Panacea, the local shopping includes the [Flea Market Tallahassee](https://www.expedia.ca/Flea-Market-Tallahassee-Hotels.0-l553248621587242546-0.Travel-Guide-Filter-Hotels), 40.2km away, offering a vibrant atmosphere. If you're up for a drive, check out the [Tallahassee Downtown Market](https://www.expedia.ca/Tallahassee-Downtown-Market-Hotels.0-l553248621533122360-0.Travel-Guide-Filter-Hotels) and [Governor's Square Mall](https://www.expedia.ca/Governors-Square-Mall-Hotels.0-l6127864-0.Travel-Guide-Filter-Hotels), both 46.7km away, for a mix of entertainment and unique finds. **Recreation** Experience the [St. James Bay Golf Club](https://www.expedia.ca/St-James-Bay-Golf-Club-Hotels.0-l553248621532653555-0.Travel-Guide-Filter-Hotels), where you can enjoy a round of golf amidst beautiful landscapes just 20.9km from Panacea. For relaxation, Woolley Park and Morrison Hammock Scenic Area, both nearby, offer serene environments perfect for unwinding and connecting with nature. **Adventure** The [Tallahassee-Saint Marks Historic Railroad Trail State Park](https://www.expedia.ca/Tallahassee-Saint-Marks-Historic-Railroad-Trail-State-Park-Hotels.0-l553248621563220102-0.Travel-Guide-Filter-Hotels), located 43.5km from Panacea, invites you to hike through picturesque landscapes. Similarly, the [Tallahassee-St. Marks Historic Railroad State Trail](https://www.expedia.ca/Tallahassee-St-Marks-Historic-Railroad-State-Trail-Hotels.0-l553248621532654100-0.Travel-Guide-Filter-Hotels), 46.7km away, offers stunning scenery. Experience the serene beauty of the [Saint Marks Trail](https://www.expedia.ca/Saint-Marks-Trail-Hotels.0-l553248621532654052-0.Travel-Guide-Filter-Hotels), situated 45.1km from Panacea. **Nightlife** In Panacea, [Theatre Tallahassee](https://www.expedia.ca/Theatre-Tallahassee-Hotels.0-l553248621561885522-0.Travel-Guide-Filter-Hotels) is a captivating destination for nightlife. Located 49.9km away, it offers a blend of culture and entertainment, perfect for a romantic evening or a family outing. Enjoy a memorable performance in a welcoming atmosphere that highlights the local arts scene. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Panacea To save money during your visit to Panacea, Florida, consider travelling in July or between December and January when prices are lower. Aim to book your stay for a Monday, as it offers the best rates compared to Fridays. Use Expedia's search tool to find budget-friendly accommodations by arranging prices from lowest to highest. Additionally, consider booking a package that combines your hotel with flights and activities for further savings. Take advantage of the area's free activities and explore local sights on foot or via affordable public transport to keep costs down. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Panacea are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Panacea is Monday. The most expensive day to stay in Panacea is Friday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your options based on your budget, preferred location, and desired type of accommodation. To find the best prices and deals, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your Panacea hotel reservation with your flights and activities through an Expedia package. ### Find the best attractions in Panacea Panacea, Florida, is an ideal destination for beach lovers and outdoor enthusiasts seeking scenic beauty. Visitors can explore local attractions such as Panacea Park and enjoy the nearby national and state parks, as well as stunning islands. With its inviting beaches and natural landscapes, Panacea offers a perfect getaway for those looking to unwind in nature and experience the great outdoors. - **[Alligator Point Beach: ](https://www.expedia.ca/Alligator-Point-Beach-Hotels.0-l553248635983992302-0.Travel-Guide-Filter-Hotels)** Experience the laid-back beach vibes at Alligator Point Beach, where you can relax on soft sands, swim in crystal-clear waters, and enjoy stunning sunsets over the Gulf of Mexico. - **[Bald Point State Park: ](https://www.expedia.ca/Bald-Point-State-Park-Hotels.0-l553248621532654045-0.Travel-Guide-Filter-Hotels)** Embrace adventure and breathtaking scenery at Bald Point State Park. Explore winding trails, spot diverse wildlife, and take in panoramic views of the coastline, perfect for hiking and birdwatching enthusiasts. - **[USS Mohawk CGC Veterans Memorial Reef: ](https://www.expedia.ca/USS-Mohawk-CGC-Veterans-Memorial-Reef-Hotels.0-l553248621561885546-0.Travel-Guide-Filter-Hotels)** Dive into history at the USS Mohawk CGC Veterans Memorial Reef. This unique underwater site honours veterans while offering an incredible opportunity for snorkelling and diving among vibrant marine life. ### Best time to go to Panacea The best time to visit Panacea can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Panacea falls in July and August. August has average visitor numbers and mostly sunny weather. The coolest average temperature in Panacea falls in January, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 53.6°F (12.0°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 57.6°F (14.2°C) | Light Rain | Mostly Sunny | Average | Average | | March | 62.4°F (16.9°C) | Light Rain | Mostly Sunny | Average | Average | | April | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Moderately High | Average | | May | 74.8°F (23.8°C) | Light Rain | Mostly Sunny | Average | Slightly High | | June | 80.4°F (26.9°C) | Moderate Rain | Mostly Sunny | Moderately High | Average | | July | 81.7°F (27.6°C) | Moderate Rain | Mostly Sunny | Moderately High | Slightly Low | | August | 81.7°F (27.6°C) | Moderate Rain | Mostly Sunny | Average | Average | | September | 78.4°F (25.8°C) | Light Rain | Mostly Sunny | Average | Slightly High | | October | 71.1°F (21.7°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly High | | November | 61.9°F (16.6°C) | Light Rain | Mostly Sunny | Moderately Low | Average | | December | 57.6°F (14.2°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly Low | ### The nearest major airports for your trip to Panacea If you're planning a visit to Panacea, Florida, the nearest major airport is Tallahassee International Airport ([TLH](https://www.expedia.ca/Tallahassee-Intl-Airport-Hotels.0-aTLH-0.Travel-Guide-Filter-Hotels)), situated 41.8km away. For accommodation, consider the [DoubleTree by Hilton Hotel Tallahassee](https://www.expedia.ca/Tallahassee-Hotels-DoubleTree-By-Hilton-Hotel-Tallahassee.h25028.Hotel-Information) and [Hotel Duval](https://www.expedia.ca/Tallahassee-Hotels-Hotel-Duval.h9568.Hotel-Information), both 8.0km from TLH, offering convenient airport shuttle services. Another option is the Hotel Indigo Tallahassee - Collegetown, located 6.4km from the airport. All these hotels provide easy access to the airport, ensuring a seamless travel experience during your stay in Panacea. ## Recent reviews of Panacea hotels ![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg) ### The Panacea Motel 5/5 Excellent "Excellent stay! Very clean and spacious room! Staff was friendly and helpful " A verified traveller stayed at The Panacea Motel Posted 3 days ago [](https://expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.](https://images.trvl-media.com/lodging/97000000/96100000/96093100/96093081/74dd4b58_y.jpg) ### Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs. 5/5 Excellent "We LOVED our stay at the Tiki House. The location is on our favorite part of Alligator Point (Mud Cove). Our son loves to cast the net for the Mullet and Shrimp that come into the Mud Cove area during this time of year. Loved the large kitchen bar that was perfect for our traditional Thanksgiving meal. The screened porch is so comfortable along with the wonderful views from the adjoining deck. We enjoyed everything about the Tiki House. Thank you, Russ and Tam, for another wonderful memory at Alligator Point!!" A verified traveller stayed at Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs. Posted 4 days ago [](https://expedia.ca/Panacea-Hotels-Unique-Beach-Front-Gathering-Spot-For-Family.h96093081.Hotel-Information) ![Coastal Getaway on canal-steps to the beach](https://images.trvl-media.com/lodging/79000000/78440000/78437300/78437246/22f909a1_y.jpg) ### Coastal Getaway on canal-steps to the beach 5/5 Excellent "Nice and clean, comfortable beds and a nice quiet area. We had everything we needed." A verified traveller stayed at Coastal Getaway on canal-steps to the beach Posted 10 days ago [](https://expedia.ca/Panacea-Hotels-Coastal-Getaway-On-Canal-Steps-To-The-Beach.h78437246.Hotel-Information) ![PRIVATE LUXURY BEACHFRONT HOME!](https://images.trvl-media.com/lodging/56000000/55370000/55361200/55361115/c761bdff_y.jpg) ### PRIVATE LUXURY BEACHFRONT HOME! 5/5 Excellent "Great amenities and very clean." A verified traveller stayed at PRIVATE LUXURY BEACHFRONT HOME! Posted 2 weeks ago [](https://expedia.ca/Panacea-Hotels-NEW-5-Bedroom-5-Bathroom-Beachfront-Home-With-Views-From-Every-Room.h55361115.Hotel-Information) ![Hideaway Beach Cottage on waterfront with amazing views.](https://images.trvl-media.com/lodging/89000000/89000000/88994400/88994349/3f6eb453_y.jpg) ### Hideaway Beach Cottage on waterfront with amazing views. 5/5 Excellent "Awesome little hideaway! Peaceful retreat to rejuvenate with top shelf sunsets, amazing. Close to restaurants, sea lab, Mash’s Sand beach, Alligator Point and State park. Host was super too." A verified traveller stayed at Hideaway Beach Cottage on waterfront with amazing views. Posted 2 weeks ago [](https://expedia.ca/Panacea-Hotels-Hideaway-Beach-Cottage-On-Waterfront-With-Amazing-Views.h88994349.Hotel-Information) ![NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!](https://images.trvl-media.com/lodging/119000000/118720000/118717600/118717563/eedfea7d_y.jpg) ### NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property! 5/5 Excellent "The best place to stay in Panacea. Very spacious and a bathroom for each bedroom. It doesn’t get any better than this." A verified traveller stayed at NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property! Posted 3 weeks ago [](https://expedia.ca/Panacea-Hotels-Spacious-4BR45BA-Bald-Point-Beach-Home-Perfect-For-Families-Groups.h118717563.Hotel-Information) ![7 Bedroom Beach House with POOL!! Gulf Front and Bay Front](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/df15e6fc_y.jpg) ### 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front 5/5 Excellent "Our family had a great time. There was plenty of space for everyone to be alone when they needed it, but absolutely plenty of space to come together. Kitchen was fully stocked with all of the pots/pans/utensils needed. The house is right on the water with convenient access. The front yard was perfect for our dog. The beach amenities were great. Contact with the host was quick and easy. We loved it and would love to come back. " A verified traveller stayed at 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front Posted 1 month ago [](https://expedia.ca/Panacea-Hotels-7-Bedroom-Beach-House-With-POOL-Gulf-Front-And-Bay-Front.h19008298.Hotel-Information) !["Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8 ](https://images.trvl-media.com/lodging/64000000/63080000/63079600/63079590/63c77c39_y.jpg) ### "Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8 5/5 Excellent "This is our 2nd time visiting. We absolutely love this house and the view! " A verified traveller from Carrollton GA stayed at "Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8 Posted 1 month ago [](https://expedia.ca/Panacea-Hotels-Shifting-Sands-Private-Beach-Front-3-Bd.h63079590.Hotel-Information) ![Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi](https://images.trvl-media.com/lodging/27000000/26600000/26599500/26599452/09f71ac2_y.jpg) ### Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi 5/5 Excellent "This is such a unique home with added touches to the decor that just made us feel like we were at a beach cottage with lots of history. Communication with Allison was and has always been top-notch. She gets back to us usually within a few hours with any questions, sometimes sooner. Also, love having access to both the bay and the Gulf of America!" A verified traveller stayed at Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi Posted 1 month ago [](https://expedia.ca/Panacea-Hotels-Happy-Shack-BEACH-BAY-Kayak.h26599452.Hotel-Information) ## Frequently asked questions ### What are the best budget hotels in Panacea? ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Panacea hotel booking with Expedia? ### How much is the nightly rate at a Panacea hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [2 Star Hotels in Carrabelle ](https://www.expedia.ca/2Star-Carrabelle-Hotels.s20-0-d86458.Travel-Guide-Filter-Hotels) - [Farmstay in Alligator Point ](https://www.expedia.ca/Alligator-Point-Agritourism.d553248635975849030-aaAgritourism.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Alligator Point ](https://www.expedia.ca/Alligator-Point-Hotels-Beach-Hotel.0-0-d553248635975849030-tBeachHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Alligator Point ](https://www.expedia.ca/Alligator-Point-Hotels-Cheap-Hotels.0-0-d553248635975849030-tCheapHotels.Travel-Guide-Filter-Hotels) - 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