Title: 4 Stars Hotels in Panacea, Florida  - Find Cheap Panacea Hotels With 4 Stars | Expedia.ca

[Panacea Travel Guide](https://expedia.ca/Panacea.dx3000431554)[Hotels in Panacea](https://expedia.ca/Panacea-Hotels.d3000431554.Travel-Guide-Hotels)[Vacation Rentals in Panacea](https://expedia.ca/Panacea-Vacation-Rentals.d3000431554.Travel-Guide-VacationRentals)[Flights to Panacea](https://expedia.ca/Cheap-Flights-To-Panacea.d3000431554.Travel-Guide-Flights)[Panacea Car Rentals](https://expedia.ca/Car-Rentals-In-Panacea.d3000431554.Car-Rental-Guide)[Panacea Vacation Packages](https://expedia.ca/Panacea.d3000431554.Destination-Travel-Guides)

![Beautiful uncrowned beaches](https://images.trvl-media.com/place/553248635975849030/3897830d-0364-4ff9-a71f-9d53f3b3a805.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Barbara Brogdon

# 4 Stars Hotels in Panacea, Florida 

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## Check availability on Panacea 4 Star Hotels

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[Jan 3 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2026-01-03&endDate=2026-01-04&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

[See all hotels in Panacea](https://www.expedia.ca/Hotel-Search?startDate=2026-01-17&endDate=2026-01-18&adults=2&regionId=3000431554)

![Sunset over a lake at Panacea, northern Florida, USA | NONE |](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd.jpg?impolicy=fcrop&w=267&h=399&p=1&q=high)

## Top Panacea Hotel Reviews

## Find out more about Panacea

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Panacea are calling your name. Known for providing first-rate service in amazing locations, each of the Panacea 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Panacea. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Panacea, Florida, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Panacea hotels with 4 Stars provide everything you need to unwind in style.

## Frequently asked questions

### How much does it cost to stay in a 4-star hotel in Panacea?

> - Search for the lowest price

### What's the difference between 5-star and 4-star hotels in Panacea?

### Does Panacea have any 4-star all-inclusive resorts?

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