Oronoco Vacation Rentals

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Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3

Our top choices for Oronoco vacation homes

A two-story house with a covered patio and a pathway leading to the entrance.

1. Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (172 reviews)
"This was perfect place for our 2 night stay. Clean and comfortable and at the right price!"
United States
Pam N.
The price is CA $146
CA $252 total
includes taxes & fees
Nov 9 - Nov 10
Magical Nest Hideaway
A modern kitchen with white cabinets, a built-in oven, and a coffee maker.

2. UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK

UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK
East Side Pioneers
The price is CA $145
CA $320 total
includes taxes & fees
Nov 14 - Nov 15
UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK
A living room with a dark blue armchair, a black entertainment unit with a TV displaying a scenic view, a white door, and a window with a view of a car outside.

3. 1mile to Mayo 2 step entry Brave Covered By Faith

1mile to Mayo 2 step entry Brave Covered By Faith
Parkway
10.0 out of 10, Exceptional, (11 reviews)
"This was a PERFECT place to stay if you're going to the Mayo!Jessica is very easy to work with and incredibly responsive!"
United States
Kristin T.
The price is CA $119
CA $373 total
includes taxes & fees
Nov 10 - Nov 11
1mile to Mayo 2 step entry Brave Covered By Faith
A wooden tray with a bottle and a remote control on a table, with a sofa and decorative pillows in the background.

4. Little Nest | 2 mi to Mayo Clinic, 2 bed w/Lg Yard

Little Nest | 2 mi to Mayo Clinic, 2 bed w/Lg Yard
Rochester
10.0 out of 10, Exceptional, (1 review)
"The Little Nest was a perfect place for us to stay while in Rochester. It was easy access to where we needed to be check-in was a breeze and Becca our host was above and beyond."
United States
pat o.
The price is CA $183
CA $552 total
includes taxes & fees
Nov 11 - Nov 12
Little Nest | 2 mi to Mayo Clinic, 2 bed w/Lg Yard
A dining room with a white table, white chairs, a chandelier, and a potted plant.

5. Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
East Side Pioneers
9.4 out of 10, Exceptional, (25 reviews)
"Very clean place with a very welcoming environment made us feel right at home!!"
United States
Nadaley W.
The price is CA $131
CA $313 total
includes taxes & fees
Nov 11 - Nov 12
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
A living room with a sectional sofa, a dining table, and a kitchen in the background.

6. Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Washington
10.0 out of 10, Exceptional, (49 reviews)
"Great place to stay. Near Mayo, grocery, and other shopping. Very dog friendly. Would stay again."
United States
Ann G.
The price is CA $255
CA $318 total
includes taxes & fees
Nov 20 - Nov 21
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
A bedroom with a bed, two bedside tables, a nightstand, a lamp, and a curtain.

7. Luxurious Sweet Escape stunning custom Home!

Luxurious Sweet Escape stunning custom Home!
Rochester
10.0 out of 10, Exceptional, (3 reviews)
"The home more than met our needs for the length of time that we stayed. The host was easy to contact and was prompt in her responses. Would recommend if anyone needs to stay in Rochester."
United States
Patrick F.
The price is CA $466
CA $648 total
includes taxes & fees
Dec 3 - Dec 4
Luxurious Sweet Escape stunning custom Home!
A modern kitchen with stainless steel appliances, white cabinetry, and a window with a view of greenery.

8. The Little House | 1 mi from downtown, Love Pets!

The Little House | 1 mi from downtown, Love Pets!
Slatterly Park
10.0 out of 10, Exceptional, (23 reviews)
"Beautiful little house and comfortable stay."
United States
Cheryl P.
The price is CA $170
CA $383 total
includes taxes & fees
Nov 22 - Nov 23
The Little House | 1 mi from downtown, Love Pets!
A living room with a brown armchair, a grey sofa, a small table with a lamp, and a window with curtains.

9. 1mile Mayo 2 step entry Encourage CoveredByFaith

1mile Mayo 2 step entry Encourage CoveredByFaith
Parkway
10.0 out of 10, Exceptional, (2 reviews)
"Nice little place and close to the Mayo Clinic. It was perfect. "
United States
Philip
The price is CA $144
CA $407 total
includes taxes & fees
Nov 23 - Nov 24
1mile Mayo 2 step entry Encourage CoveredByFaith
A modern two-story house with a black garage door, large windows, and a small balcony.

10. 1st Luxury Residential Elevator rooftop deck

1st Luxury Residential Elevator rooftop deck
Rochester
The price is CA $407
CA $616 total
includes taxes & fees
Nov 9 - Nov 10
1st Luxury Residential Elevator rooftop deck
A kitchen with white cabinets, a stove, oven, microwave, and a sink.

11. 2 Blks St Marys 2 Main Fl Beds Bath CoveredByFaith

2 Blks St Marys 2 Main Fl Beds Bath CoveredByFaith
Kutzky Park
10.0 out of 10, Exceptional, (105 reviews)
"The location was great as a family member recovered from surgery. A short walk to St Mary’s!"
United States
Carla L.
The price is CA $154
CA $418 total
includes taxes & fees
Nov 16 - Nov 17
2 Blks St Marys 2 Main Fl Beds Bath CoveredByFaith
A neatly arranged bedroom with a bed, bedside table, lamp, and a dresser with a mirror.

12. Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.

Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.
Rochester
10.0 out of 10, Exceptional, (11 reviews)
"Nice place to stay, close to all the activities we wanted to do."
United States
Kimberly K.
The price is CA $224
CA $665 total
includes taxes & fees
Nov 9 - Nov 10
Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.
A modern kitchen with wooden cabinets, a stainless steel refrigerator, and a built-in oven.

13. 2-bedroom house Walk to Silver Lake & Downtown Rochester

2-bedroom house Walk to Silver Lake & Downtown Rochester
Northrup
2-bedroom house Walk to Silver Lake & Downtown Rochester
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a dishwasher, and a window with a view of greenery.

14. ColorHouse | 1 mi to Mayo Clinic, No Stairs Entry

ColorHouse | 1 mi to Mayo Clinic, No Stairs Entry
East Side Pioneers
9.0 out of 10, Wonderful, (15 reviews)
"Great place!"
United States
Jeremiah E.
The price is CA $210
CA $473 total
includes taxes & fees
Nov 11 - Nov 12
ColorHouse | 1 mi to Mayo Clinic, No Stairs Entry
A modern kitchen with a central island, bar stools, and a view of the backyard through large sliding doors.

15. Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester
Slatterly Park
10.0 out of 10, Exceptional, (46 reviews)
"Immaculate house with room for us to spread out! Perfect stay."
United States
Sarah F.
The price is CA $282
CA $352 total
includes taxes & fees
Nov 15 - Nov 16
Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester
A residential deck with a glass railing, a covered area with a sloped roof, and a view of a tree-lined landscape.

16. Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
Rochester
10.0 out of 10, Exceptional, (6 reviews)
"We enjoyed our stay here. Nice location easy to get to things in Rochester. "
United States
Jonathan P.
The price is CA $465
CA $581 total
includes taxes & fees
Nov 10 - Nov 11
Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
A living room with a flat-screen TV on a wooden stand, a gray sofa, and a blue armchair.

17. Close to Mayo/Shops, 1 step entry Covered By Faith

Close to Mayo/Shops, 1 step entry Covered By Faith
Rochester
9.8 out of 10, Exceptional, (13 reviews)
"The host was so incredibly responsive whenever we had questions, the house was incredibly clean and welcoming, and we enjoyed our stay there."
United States
Anonymous traveller
The price is CA $146
CA $406 total
includes taxes & fees
Nov 10 - Nov 11
Close to Mayo/Shops, 1 step entry Covered By Faith
A dining area with a wooden floor, a table with chairs, a rug, and a window with blinds.

18. HartHouse | 5 Min Walk to Mayo St Marys, Historic Kutzky

HartHouse | 5 Min Walk to Mayo St Marys, Historic Kutzky
Kutzky Park
10.0 out of 10, Exceptional, (4 reviews)
"Fun neighborhood good bars and restaurants "
United States
David M.
HartHouse | 5 Min Walk to Mayo St Marys, Historic Kutzky
A modern kitchen with dark wooden cabinets, a central island with bar stools, and pendant lighting.

19. Custom Luxury Rambler in Highland Hills, Rochester

Custom Luxury Rambler in Highland Hills, Rochester
Rochester
10.0 out of 10, Exceptional, (1 review)
"Hi, I gave 5 stars but wanted to give a few tips. Please have extra bedding & pillows available. "
United States
Whitney M.
Custom Luxury Rambler in Highland Hills, Rochester
A bedroom with a large bed, a ceiling light, a window with curtains, a wall-mounted TV, and a bookshelf.

20. Mayo Clinic Cottage - Power Bed & Recliners

Mayo Clinic Cottage - Power Bed & Recliners
Northrup
Mayo Clinic Cottage - Power Bed & Recliners
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top reviews in Oronoco

A modern dining area with high tables, chairs, and pendant lighting.
Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
Rochester

10/10 Excellent

The staff was courteous and flexible.
Canada
Anthony
Reviewed September 23, 2026
Hampton Inn & Suites Rochester-North

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