
Opelousas Vacation Packages
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- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
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Your Opelousas Vacation
There's no better way to embark on an adventure than with one of our vacation packages to Opelousas. The rich history and cultural experiences are a couple of the countless reasons to spend some time in this interesting city. Be sure to spend time sightseeing during your trip to Opelousas. Louisiana Orphan Train Museum and St. Landry Catholic Church are some well-known attractions to check out. Don't delay visiting this destination any longer. Your dream Opelousas vacation is a couple of clicks away with Expedia.
Opelousas Hotel Deals

Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd Opelousas LA
Fully refundableReserve now, pay when you stay
The price is CA $97 per night from Nov 29 to Nov 30
CA $97
CA $114 total
Nov 29 - Nov 30
includes taxes & fees
7/10 Good! (786 reviews)
"The property overall was run down. Someone had a dog that barked at all hours of the night."
Reviewed on Nov 11, 2026

Hampton Inn Opelousas
1700 Commerce Blvd Opelousas LA
Fully refundableReserve now, pay when you stay
The price is CA $145 per night from Dec 13 to Dec 14
CA $145
CA $170 total
Dec 13 - Dec 14
includes taxes & fees
8.4/10 Very good! (388 reviews)
"Great friendly staff, always provides us with great service"
Reviewed on Nov 9, 2026

Holiday Inn Express & Suites Opelousas by IHG
5696 I-49 N Service Rd Opelousas LA
Fully refundable
The price is CA $180 per night from Dec 13 to Dec 14
CA $180
CA $212 total
Dec 13 - Dec 14
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Opelousas attractions
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.







