The historic Dutch Romanesque Revival style Cathedral of Saint John the Evangelist or La Cathedrale St-Jean built in 1916 on Cathedral Street in downtown Lafayette, Louisiana, USA

Opelousas Vacation Rentals

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Our top choices for Opelousas vacation rentals

Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes
4.0 star property
Lafayette
The price is CA $160
CA $328 total
includes taxes & fees
Jul 7 - Jul 8
Enclave 3 Bedroom Luxury Homes

Enclave 1 Bedroom Suites

Enclave 1 Bedroom Suites
3.0 star property
Lafayette
9.0 out of 10, Wonderful, (12 reviews)
"This was a great place to stay. I would definitely rebook this location."
United States
Jessica
The price is CA $108
CA $209 total
includes taxes & fees
Jul 6 - Jul 7
Enclave 1 Bedroom Suites

The Royal Inn

The Royal Inn
4.0 star property
Lafayette
The price is CA $148
CA $331 total
includes taxes & fees
Jul 7 - Jul 8
The Royal Inn

Magazine Inn

Magazine Inn
3.5 star property
Lafayette
The price is CA $151
CA $333 total
includes taxes & fees
Jun 30 - Jul 1
Magazine Inn

Rampart Inn

Rampart Inn
4.0 star property
Lafayette
The price is CA $161
CA $338 total
includes taxes & fees
Jun 29 - Jun 30
Rampart Inn

Decatur Inn

Decatur Inn
4.0 star property
Lafayette
The price is CA $161
CA $338 total
includes taxes & fees
Jun 28 - Jun 29
Decatur Inn

Poydras Inn

Poydras Inn
4.0 star property
Lafayette
The price is CA $150
CA $326 total
includes taxes & fees
Jun 29 - Jun 30
Poydras Inn

Enclave 2 Bedroom Luxury Homes

Enclave 2 Bedroom Luxury Homes
3.0 star property
Lafayette
9.6 out of 10, Exceptional, (5 reviews)
"Super clean and quiet. Beds are very comfortable."
United States
April
The price is CA $159
CA $305 total
includes taxes & fees
Jun 28 - Jun 29
Enclave 2 Bedroom Luxury Homes

Esplanade Inn

Esplanade Inn
4.0 star property
Lafayette
The price is CA $142
CA $317 total
includes taxes & fees
Jun 26 - Jun 27
Esplanade Inn

Walk to Downtown Scene

Walk to Downtown Scene
2.0 star property
Downtown Lafayette
The price is CA $154
CA $296 total
includes taxes & fees
Jun 30 - Jul 1
Walk to Downtown Scene

Maison D'Memoire Bed & Breakfast Cottages

Maison D'Memoire Bed & Breakfast Cottages
4.0 star property
Rayne
9.6 out of 10, Exceptional, (97 reviews)
"We enjoy the history of the property. Hosts are such delightful people!"
United States
Susan
The price is CA $245
CA $277 total
includes taxes & fees
Jun 30 - Jul 1
Maison D'Memoire Bed & Breakfast Cottages

Spacious Corporate Lodging in Downtown Lafayette

Spacious Corporate Lodging in Downtown Lafayette
2.0 star property
McComb-Veazey
The price is CA $334
CA $658 total
includes taxes & fees
Jun 30 - Jul 1
Spacious Corporate Lodging in Downtown Lafayette

Spacious 4BR Retreat in the Heart of Lafayette

Spacious 4BR Retreat in the Heart of Lafayette
2.0 star property
Freetown - Port Rico
The price is CA $174
CA $346 total
includes taxes & fees
Jul 1 - Jul 2
Spacious 4BR Retreat in the Heart of Lafayette

Magnolia House in Lafayette

Magnolia House in Lafayette
2.0 star property
McComb-Veazey
10.0 out of 10, Exceptional, (1 review)
The price is CA $236
CA $418 total
includes taxes & fees
Jul 21 - Jul 22
Magnolia House in Lafayette

Work Crew Haven Spacious Corporate Lodging

Work Crew Haven Spacious Corporate Lodging
2.0 star property
McComb-Veazey
The price is CA $943
CA $1,487 total
includes taxes & fees
Jul 1 - Jul 2
Work Crew Haven Spacious Corporate Lodging

Peaceful and Private Retreat

Peaceful and Private Retreat
2.0 star property
Downtown Lafayette
2.0 out of 10, (1 review)
"Changed the location and received no notification of it until driving to the place"
United States
Nicole
The price is CA $176
CA $312 total
includes taxes & fees
Jul 7 - Jul 8
Peaceful and Private Retreat

Third Street House in Lafayette

Third Street House in Lafayette
2.0 star property
McComb-Veazey
2.0 out of 10, (1 review)
"Upon arrival i was taken aback. There was a tarp on the roof on signs of construction in the front yard. In order to get into the home you have to walk around the house to the back door. Upon entry there were signs of water damage in the ceiling. Fast forward l....had electricity upon check-in but after returning, about 5 hours later the electricity said look for me.....yeah not an ounce of electricity at the residence. The home could really use an update. Aside from the electrcity issue, i felt...
United States
Anonymous traveller
The price is CA $203
CA $379 total
includes taxes & fees
Jul 1 - Jul 2
Third Street House in Lafayette

Corporate Comfort Ideal Accommodation for Work Crews

Corporate Comfort Ideal Accommodation for Work Crews
2.0 star property
McComb-Veazey
The price is CA $463
CA $843 total
includes taxes & fees
Jul 21 - Jul 22
Corporate Comfort Ideal Accommodation for Work Crews

Evangeline A in Lafayette

Evangeline A in Lafayette
2.0 star property
McComb-Veazey
10.0 out of 10, Exceptional, (1 review)
"Such a cute little gem, right outside of downtown Lafayette. The house was lovely inside and out. The recent renovations and layout of the house makes it feel so much bigger than it is. The vaulted ceilings, and beautiful attention to details in the interior design made this a new place to stay when we visit! "
United States
William
The price is CA $108
CA $179 total
includes taxes & fees
Jun 30 - Jul 1
Evangeline A in Lafayette

Steps From Downtown Minutes to the Airport

Steps From Downtown Minutes to the Airport
2.0 star property
McComb-Veazey
10.0 out of 10, Exceptional, (1 review)
"Great place and everything worked as should Lots Of rooms"
United States
joseph
The price is CA $179
CA $353 total
includes taxes & fees
Jul 6 - Jul 7
Steps From Downtown Minutes to the Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Opelousas Hotel Reviews

Find out more about Opelousas

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Opelousas. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Opelousas?

Yes, we give you a choice of vacation rentals in Opelousas close to Louisiana Orphan Train Museum, or you can select a more remote option if you're looking for extra privacy while you relax. Opelousas is known for its casinos and cafes. Make sure you have time to check out the art and churches during your trip.

What are some of the best vacation rentals that Opelousas has to offer?

Enclave 1 Bedroom Suites: This vacation home rental near Opelousas has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Amenities like a coffee maker and free parking are also available for your convenience.

How many vacation rentals are there in Opelousas?

Choose from 5 Expedia vacation rentals in Opelousas for a memorable vacation.

What’s there to see and do in Opelousas?

Cultural attractions include Louisiana Orphan Train Museum and Fireman's Museum, whereas South Park is one spot to enjoy nature. Evangeline Downs Racetrack & Casino and Opelousas Historic District are other places to visit while you're in town.

What are vacation rentals like in Opelousas?

Vacation rentals are privately owned accommodations you can reserve for several days or more in Opelousas. Vacation rentals feature amenities such as kitchens and laundry facilities to help you enjoy your stay. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great option for a small group gathering.