Mission Bay Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Mission Bay

Price found within the past 48 hours. Click for updated prices.
Uptown Oasis San Jose Airport

Uptown Oasis San Jose Airport

3 out of 5
Rosemary
Price was CA $1,344, price is now CA $854 per person
CA $854
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to San Jose (SJC)
8/10 Very Good! (701 reviews)
Very cool retro. Felt like I stepped back into the 50's (though I wasn't alive then). Tiki style bar. Old school motel-restaurant. With s tropical vibe. Breakfast was good and a good price. Great staff.

Reviewed on May 6, 2026

Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square

5 out of 5
Fisherman's Wharf
Price was CA $7,447, price is now CA $4,538 per person
CA $4,538
per person
Jun 25 - Jun 30
found 15 hours ago
Roundtrip non-stop flight included
Vancouver (YVR) to San Francisco (SFO)
9.4/10 Exceptional! (400 reviews)
This is my favorite San Francisco hotel/condo. I’ve stayed here five times and highly recommend it.

Reviewed on May 6, 2026

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Price was CA $2,650, price is now CA $1,619 per person
CA $1,619
per person
Jul 5 - Jul 12
found 1 day ago
Roundtrip flight included
Toronto (YTO) to San Francisco (SFO)
9/10 Wonderful! (7,507 reviews)
The eggs were over cooked

Reviewed on May 15, 2026

The Grove Inn

The Grove Inn

3 out of 5
Western Addition
Price was CA $1,850, price is now CA $1,190 per person
CA $1,190
per person
Jul 7 - Jul 11
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to San Francisco (SFO)
9.2/10 Wonderful! (710 reviews)
Cute Inn. Comfortable. Keep in mind no parking. That is a challenge moving car. They have coffee and tea. Small frig. Great shower pressure. Comfy bed.

Reviewed on May 14, 2026

@ Marbella Lane - SJ Designer Home 3BR Ldry+p

@ Marbella Lane - SJ Designer Home 3BR Ldry+p

3 out of 5
Price was CA $5,953, price is now CA $3,904 per person
CA $3,904
per person
Jun 18 - Jun 23
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to San Jose (SJC)
No reviews

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
Union Square

Union Square

4/5(531 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Mission Bay Hotel Deals

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $300 per night from May 29 to May 30
CA $300
CA $354 total
May 29 - May 30
includes taxes & fees
9.6/10 Exceptional! (2,502 reviews)
Very clean, very accommodating.

Reviewed on May 12, 2026

LUMA Hotel San Francisco
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $204 per night from May 25 to May 26
CA $204
CA $297 total
May 25 - May 26
includes taxes & fees
9/10 Wonderful! (7,456 reviews)
The eggs were over cooked

Reviewed on May 15, 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $184 per night from May 29 to May 30
CA $184
CA $216 total
May 29 - May 30
includes taxes & fees
8.8/10 Excellent! (2,758 reviews)
Very good for business trips

Reviewed on May 14, 2026

Hilton San Francisco Financial District
See all 4,478 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Mission Bay vacation package cost?
Custom make your Mission Bay vacation package from as low as CA $854. Pick from any combination of hotels, flights and rental cars to build the getaway you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Mission Bay?
Bundle your flights and hotels, throw in extras such as activities or a rental car, and save with a Mission Bay vacation package. You won't just pick up big discounts on your adventure — you'll have a world of choice too. When you book with Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels all over the world. Your next epic adventure begins right here, right now!
Where should I stay in Mission Bay?
A trip to Mission Bay isn't complete without seeing Pier 39 and Alcatraz Island. Reserve a room close by and easily access these popular tourist attractions.
How far in advance should I book my Mission Bay vacation?
Smart travelers often book as early as possible. You can usually compare international fares on Expedia up to 12 months before your flight. If you've left booking to the last minute, fear not. Budget prices sometimes appear just weeks before departure dates.
What does an Expedia Mission Bay travel package include?
Choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on activities and tours. Want to pick your airfare class? That's possible too. The choice is all yours when it comes to putting together your perfect Mission Bay trip.
What should I know before booking a Mission Bay travel package?
You'll pick up great savings when you bundle your flights, hotels and rental cars into a package. Not only that, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're organizing an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Mission Bay Expedia vacation package?
You can, and with more than 550 airlines to choose from worldwide, you're not short on choice. Scroll through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Mission Bay vacation package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Mission Bay vacation package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still make the necessary changes, but your airline, hotel or car rental company may impose a fee. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Discover the most popular places to visit in Mission Bay

Chase Center San Francisco Skyline Aerial Photography

Chase Center

Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.

Chase Center

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

CA $67
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz Visit with Night Option and SF Bay Cruise

Alcatraz Visit with Night Option and SF Bay Cruise

CA $171
per adult
94% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

CA $149
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.